M Aumailley

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Molecular basis of inherited skin-blistering disorders, and therapeutic implications
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, and Center for Molecular Medicine Cologne, University of Cologne, Germany
    Expert Rev Mol Med 8:1-21. 2006
  2. pmc The laminin family
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Cell Adh Migr 7:48-55. 2013
  3. pmc Effects of constitutively active GTPases on fibroblast behavior
    Z G Zhang
    Institute for Biochemistry II, Joseph Stelzmann Strasse 52, 50931 Cologne, Germany
    Cell Mol Life Sci 63:82-91. 2006
  4. pmc The role of laminins in basement membrane function
    M Aumailley
    Institut für Biochemie II, Medical Faculty, Cologne, Germany
    J Anat 193:1-21. 1998
  5. ncbi request reprint Laminin 5 processing and its integration into the ECM
    Monique Aumailley
    Institute for Biochemistry, Medical Faculty, University of Cologne, Joseph Stelzmann Str 52, Germany
    Matrix Biol 22:49-54. 2003
  6. ncbi request reprint Altered synthesis of laminin 1 and absence of basement membrane component deposition in (beta)1 integrin-deficient embryoid bodies
    M Aumailley
    Institute II for Biochemistry, University of Cologne, Germany
    J Cell Sci 113:259-68. 2000
  7. ncbi request reprint Laminins of the dermo-epidermal junction
    M Aumailley
    Institut II für Biochemie, Medical Faculty, Cologne, Germany
    Matrix Biol 18:19-28. 1999
  8. ncbi request reprint The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes
    V Wixler
    Institute for Biochemistry II, Medical Faculty, University of Cologne, Joseph Stelzmann Strasse 52, 50931 Cologne, Germany
    J Biol Chem 275:33669-78. 2000
  9. ncbi request reprint Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains
    V Wixler
    Institute for Biochemistry II, Medical Faculty of the University of Cologne, Germany
    FEBS Lett 445:351-5. 1999
  10. ncbi request reprint Fibroblasts contribute to the deposition of laminin 5 in the extracellular matrix
    Abdallah Elkhal
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Exp Cell Res 296:223-30. 2004

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Molecular basis of inherited skin-blistering disorders, and therapeutic implications
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, and Center for Molecular Medicine Cologne, University of Cologne, Germany
    Expert Rev Mol Med 8:1-21. 2006
    ....
  2. pmc The laminin family
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Cell Adh Migr 7:48-55. 2013
    ....
  3. pmc Effects of constitutively active GTPases on fibroblast behavior
    Z G Zhang
    Institute for Biochemistry II, Joseph Stelzmann Strasse 52, 50931 Cologne, Germany
    Cell Mol Life Sci 63:82-91. 2006
    ..In conclusion, the action of Rho GTPases appears to depend on the task cells are performing...
  4. pmc The role of laminins in basement membrane function
    M Aumailley
    Institut für Biochemie II, Medical Faculty, Cologne, Germany
    J Anat 193:1-21. 1998
    ..The consequent phenotypes highlight the pivotal role of laminins in determining heterogeneity in basement membrane functions...
  5. ncbi request reprint Laminin 5 processing and its integration into the ECM
    Monique Aumailley
    Institute for Biochemistry, Medical Faculty, University of Cologne, Joseph Stelzmann Str 52, Germany
    Matrix Biol 22:49-54. 2003
    ....
  6. ncbi request reprint Altered synthesis of laminin 1 and absence of basement membrane component deposition in (beta)1 integrin-deficient embryoid bodies
    M Aumailley
    Institute II for Biochemistry, University of Cologne, Germany
    J Cell Sci 113:259-68. 2000
    ....
  7. ncbi request reprint Laminins of the dermo-epidermal junction
    M Aumailley
    Institut II für Biochemie, Medical Faculty, Cologne, Germany
    Matrix Biol 18:19-28. 1999
    ..Furthermore, they are signaling molecules providing adjacent cells with diverse information by interacting with cell surface components...
  8. ncbi request reprint The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes
    V Wixler
    Institute for Biochemistry II, Medical Faculty, University of Cologne, Joseph Stelzmann Strasse 52, 50931 Cologne, Germany
    J Biol Chem 275:33669-78. 2000
    ..These results, together with the fact that full-length DRAL/FHL2 is found in cell adhesion complexes, suggest that it is an adaptor/docking protein involved in integrin signaling pathways...
  9. ncbi request reprint Identification of novel interaction partners for the conserved membrane proximal region of alpha-integrin cytoplasmic domains
    V Wixler
    Institute for Biochemistry II, Medical Faculty of the University of Cologne, Germany
    FEBS Lett 445:351-5. 1999
    ..The conserved membrane proximal region of the alpha3A chain was identified as the binding site for all four proteins. They, therefore, may be involved in the regulation of general functions of integrins...
  10. ncbi request reprint Fibroblasts contribute to the deposition of laminin 5 in the extracellular matrix
    Abdallah Elkhal
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Exp Cell Res 296:223-30. 2004
    ..These studies show that, although laminin 5 is a product of epithelial cells, fibroblasts contribute to its integration into the extracellular matrix architecture...
  11. pmc Defective laminin 5 processing in cylindroma cells
    Lucy Tunggal
    Department of Dermatology, Medical Faculty, Institute for Biochemistry II, University of Cologne, Joseph Stelzmann Strasse 52, 50931 Koln, Germany
    Am J Pathol 160:459-68. 2002
    ..Together, the results show that multiple molecular defects, including alteration of laminin 5 and its integrin receptors, contribute to structural aberrations of the basement membrane and associated structures in cylindromas...
  12. ncbi request reprint Mechanical tension and integrin alpha 2 beta 1 regulate fibroblast functions
    Beate Eckes
    Department of Dermatology, University of Cologne, Cologne, Germany
    J Investig Dermatol Symp Proc 11:66-72. 2006
    ..Unraveling the integrated functions of fibroblasts, collagen integrin receptors, collagen fibrils, and mechanical tension will be important to understand the molecular mechanisms underlying tissue repair and fibrosis...
  13. ncbi request reprint Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of alpha2beta1 integrin
    Zhi Gang Zhang
    Department of Dermatology, Medical Faculty, University of Cologne, 50931 Cologne, Germany
    J Cell Sci 119:1886-95. 2006
    ..The deficits observed for alpha2-deficient fibroblasts appeared to be linked to alterations in the distribution of force-bearing focal adhesions and deregulation of Rho-GTPase activation...
  14. ncbi request reprint Dissociation of the complex between CD151 and laminin-binding integrins permits migration of epithelial cells
    Gretel Chometon
    Center for Biochemistry, Medical Faculty, University of Cologne, Germany
    Exp Cell Res 312:983-95. 2006
    ..Together, these results strongly suggest that dissociation of the CD151-integrin complex permits remodeling of epithelial cell interactions with the extracellular matrix and cell migration...
  15. ncbi request reprint A simplified laminin nomenclature
    Monique Aumailley
    Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany
    Matrix Biol 24:326-32. 2005
    ..The chain origin of a domain is specified by the chain nomenclature, such as alpha1L4a. The abbreviation LM is suggested for laminin. Otherwise, the nomenclature remains unaltered...
  16. ncbi request reprint Characterization of recombinant and natural forms of the human LIM domain-containing protein FHL2
    Haquima El Mourabit
    Center for Biochemistry, Faculty of Medicine, University of Cologne, Joseph Stelzmann Str 52, Cologne 50931, Germany
    Protein Expr Purif 32:95-103. 2003
    ..The results show that both the recombinant and the natural proteins are post-translationally modified and indicate that such modifications may lead to an abnormal electrophoretic behavior of natural human FHL2...
  17. ncbi request reprint Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes
    Corinna Herz
    Department of Dermatology, University Medical Center Freiburg, Hauptstrasse 7, 79104 Freiburg, Germany
    J Biol Chem 281:36082-90. 2006
    ..It is involved in organization and anchorage of the actin cytoskeleton to integrin-associated signaling platforms...
  18. pmc Keratinocytes from patients lacking collagen XVII display a migratory phenotype
    Kaisa Tasanen
    Department of Dermatology, University of Oulu, Oulu, Finland
    Am J Pathol 164:2027-38. 2004
    ..Together, the results unravel an unexpected role of collagen XVII in the regulation of keratinocyte migration...
  19. pmc Integrin-linked kinase is required for epidermal and hair follicle morphogenesis
    Katrin Lorenz
    Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany
    J Cell Biol 177:501-13. 2007
    ..We conclude that ILK plays important roles for epidermis and hair follicle morphogenesis by modulating integrin-mediated adhesion, actin reorganization, and plasma membrane dynamics in keratinocytes...
  20. ncbi request reprint Subpopulations of human dendritic cells display a distinct phenotype and bind differentially to proteins of the extracellular matrix
    Kristine Kohl
    Department of Dermatology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Eur J Cell Biol 86:719-30. 2007
    ..In summary, subpopulations of CD34DCs and MoDCs are phenotypically related to each other, but not identical and display differential binding to components of the extracellular matrix...
  21. pmc Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin
    Monika Krampert
    Department of Biology, Institute of Cell Biology, Eidgenössishe Technische Hochschule Zurich, 8093 Zurich, Switzerland
    Mol Biol Cell 15:5242-54. 2004
    ..These results suggest that a tightly regulated expression level of stromelysin-2 is required for limited matrix degradation at the wound site, thereby controlling keratinocyte migration...