Research Topics
| S AulmannSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Transitions between flat epithelial atypia and low-grade ductal carcinoma in situ of the breastSebastian Aulmann
Institute of Pathology, Heidelberg University, Heidelberg, Germany
Am J Surg Pathol 36:1247-52. 2012..Our data demonstrate the presence of direct transitions between FEA and lg-DCIS and support the interpretation of FEA as part of the low-grade pathway in the development of breast cancer...
Invasive tubular carcinoma of the breast frequently is clonally related to flat epithelial atypia and low-grade ductal carcinoma in situSebastian Aulmann
Institute of Pathology, Heidelberg University, Heidelberg, Germany
Am J Surg Pathol 33:1646-53. 2009..Our data indicate, that in the majority of cases lg-DCIS and FEA are directly related to tubular breast cancer with a possible precursor role...
[Clonal association of flat epithelial atypia and tubular breast cancer]S Aulmann
Pathologisches Institut, Universitat Heidelberg, Im Neuenheimer Feld 220 221, 69120 Heidelberg
Pathologe 29:353-6. 2008..Our data indicate a possible precursor role of FEA in the development of tubular breast cancer...
Gains of chromosome region 3q26 in intraepithelial neoplasia and invasive squamous cell carcinoma of the vulva are frequent and independent of HPV statusS Aulmann
Institute of Pathology, University of Heidelberg, Germany
J Clin Pathol 61:1034-7. 2008..The aim of this study was to investigate the presence of chromosome 3q26 gains in the spectrum of precancerous lesions and invasive squamous cell carcinomas (SCCs) of the vulva...
[Ductal and lobular preneoplasia: role in breast cancer development]S Aulmann
Pathologisches Institut, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg, Deutschland
Pathologe 32:316-20. 2011..The aim of the present study was to evaluate the biological potential of these early low-grade lesions in the development of breast cancer...
Detection of the ASPSCR1-TFE3 gene fusion in paraffin-embedded alveolar soft part sarcomasS Aulmann
Institute of Pathology, Heidelberg University, Heidelberg, Germany
Histopathology 50:881-6. 2007..The aim of this study was to analyse the chromosomal breakpoints in paraffin-embedded tissue...
Reduction of CD44(+)/CD24(-) breast cancer cells by conventional cytotoxic chemotherapySebastian Aulmann
Institute of Pathology, Heidelberg University, 69120 Heidelberg, Germany
Hum Pathol 41:574-81. 2010..In conclusion, our findings challenge the proposed role of CD44(+)/CD24(-) cells as cancer stem cells in tumor resistance to chemotherapy as they apparently are not selected by conventional cytotoxic agents...
c-myc amplifications in primary breast carcinomas and their local recurrencesS Aulmann
Department of Pathology, University of Heidelberg, Heidelberg, Germany
J Clin Pathol 59:424-8. 2006..To evaluate the role of c-myc oncogene amplifications in the progression of invasive breast carcinomas...
Molecular characterisation of pancreatic ductal adenocarcinoma in patients under 40F Bergmann
Institute of Pathology and Department of Surgery, University of Heidelberg, Heidelberg, Germany
J Clin Pathol 59:580-4. 2006..Pancreatic ductal adenocarcinoma (PDAC) rarely affects people under 40...
The location of KIT and PDGFRA gene mutations in gastrointestinal stromal tumours is site and phenotype associatedR Penzel
The Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, D 69120 Heidelberg, Germany
J Clin Pathol 58:634-9. 2005..To assess the relation between KIT and PDGFRA mutations and the site of origin, histological phenotype, and pathomorphologically determined risk assessment in gastrointestinal stromal tumours (GISTs)...
Outcome analysis of patients with primary breast cancer initially treated at a certified academic breast unitJ Heil
Breast Unit, University of Heidelberg, Voss Strasse 9, D 69115 Heidelberg, Germany
Breast 21:303-8. 2012..Evaluation of oncological outcome and prognostic factors of patients with primary breast cancer treated at a certified academic breast unit...
[Concepts and problems of lobular neoplasia]H P Sinn
Pathologisches Institut, Universitatsklinikum, Im Neuenheimer Feld 220, 69120, Heidelberg, Germany
Pathologe 27:373-80. 2006..The molecular characteristics of LN are similar to those of invasive lobular carcinomas, indicating the nature of LN as a precursor lesion...
Quality of life after emergency vs. elective esophagectomy with cervical reconstructionL Schneider
Department of General Surgery, University of Heidelberg, Heidelberg, Germany
Scand J Surg 99:3-8. 2010..The aim of this study was to explore a potential difference in QOL between elective and emergency esophagectomy with collar reconstruction...
Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomasH Blaker
Institute of Pathology, University of Heidelberg, Germany
Scand J Gastroenterol 39:748-53. 2004..The aim of this study on small intestinal carcinomas was to analyze alternative mechanisms of activation of pathways that are typically affected in colorectal cancer...
[Villous adenoma within an urachal diverticulum associated with long-term mucusuria]S Macher-Goeppinger
Institut fur Pathologie, Universitat Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg
Pathologe 29:305-7. 2008..After surgical resection histologic examination showed a mucus producing, intestinally differentiated adenoma within the diverticulum. This finding explains both the recurrent infections and the 10-year history of mucusuria...
Apoptosis resistance in pigmented villonodular synovitisI Berger
Institute of Pathology, University of Heidelberg, 69120 Heidelberg, Germany
Histol Histopathol 20:11-7. 2005..Pigmented villonodular synovitis (PVNS) is a proliferative lesion originating from synovial tissue with a locally aggressive behaviour. We analysed the pathogenetic role of apoptosis resistance for sustained cell proliferation in PVNS...
[Lobular carcinoma in situ (LCIS): risk factor and precursor of invasive lobular breast cancer]S Aulmann
Pathologisches Institut, Universitäitsklinikum Heidelberg
Verh Dtsch Ges Pathol 91:208-13. 2007..Apparently, LCIS has a chimeric role in breast cancer development and is not only a risk factor but in some cases a precursor of ILC...
