Research Topics
Species | D AuerbachSummaryAffiliation: University of Potsdam Country: Germany Publications
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Detail Information
Publications
Expression of sarcomeric proteins and assembly of myofibrils in the putative myofibroblast cell line BHK-21/C13P F van der Ven
Department of Cell Biology, University of Potsdam, Germany
J Muscle Res Cell Motil 19:767-75. 1998..At the same time, its transfectability offers an invaluable tool for in vivo studies concerning binding properties of sarcomeric proteins...
Thick filament assembly occurs after the formation of a cytoskeletal scaffoldP F van der Ven
Department of Cell Biology, Institute of Zoophysiology and Cell Biology, University of Potsdam, Germany
J Muscle Res Cell Motil 20:569-79. 1999..We therefore conclude that the correct assembly of a cytoskeletal scaffold is a prerequisite for correct thick filament assembly and for the integration of the contractile apparatus into the myofibril...
A functional knock-out of titin results in defective myofibril assemblyP F van der Ven
Department of Cell Biology, University of Potsdam, Lennéstr 7a, D 14471 Potsdam, Germany
J Cell Sci 113:1405-14. 2000..These experiments provide the first direct evidence for the crucial role of titin in both thick filament formation as a molecular ruler and in the coordination of myofibrillogenesis...
Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilinP F van der Ven
Department of Cell Biology, University of Potsdam, D 14471 Potsdam, Germany
J Cell Biol 151:235-48. 2000..Since defects in the myotilin gene were recently reported to cause a form of autosomal dominant limb-girdle muscular dystrophy, our findings provide a further contribution to the molecular understanding of this disease...
Tissue-specific isoforms of chicken myomesin are generated by alternative splicingS Bantle
Institute for Cell Biology, Swiss Federal Institute of Technology, 8093 Zurich, Switzerland
J Biol Chem 271:19042-52. 1996..We postulate that myomesin, M-protein, and skelemin belong to the same subfamily of high molecular weight M-band-associated proteins of the immunoglobulin superfamily and that they probably have the same ancestor in evolution...
A novel marker for vertebrate embryonic heart, the EH-myomesin isoformI Agarkova
Institute of Cell Biology, ETH Zurich Honggerberg, CH 8093 Zurich, Switzerland
J Biol Chem 275:10256-64. 2000..It represents the major myomesin isoform at early embryonic stages of heart but is rapidly down-regulated around birth. Thus, the strict developmental regulation of the EH-myomesin makes it an ideally suited marker for embryonic heart...
