Research Topics
| Jurgen AngererSummaryAffiliation: University of Erlangen-Nuremberg Country: Germany Publications
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Detail Information
Publications
Acrylamide exposure via the diet: influence of fasting on urinary mercapturic acid metabolite excretion in humansMelanie I Boettcher
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen, Germany
Arch Toxicol 80:817-9. 2006..This confirms that the diet is the main source of environmental AA exposure in humans, apart from smoking. Other possible AA sources could be of minor quantitative importance only...
Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study populationEva C Hartmann
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
J Agric Food Chem 56:6061-8. 2008..The ratio GAMA/AAMA is significantly higher in the group of young children (6-10 years) with a median level of 0.5. A gender-related difference in internal exposure and metabolism was not observed...- Human biomonitoring: state of the artJurgen Angerer
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Int J Hyg Environ Health 210:201-28. 2007..For the evaluation of HBM results the German HBM Commission elaborates reference- and HBM-values... - Preliminary observations on perfluorinated compounds in plasma samples (1977-2004) of young German adults from an area with perfluorooctanoate-contaminated drinking waterMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, 44801 Bochum, Germany
Int J Hyg Environ Health 212:142-5. 2009..There was a close association between PFOS and PFOA-plasma levels. From this pilot study there are no indications for an increased exposure to PFCs of residents in Arnsberg in the years 1977-2004 prior to the contamination in 2006... - Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjectsBirgitta Kütting
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich Alexander University of Erlangen Nuremberg, Schillerstr 25 29, D 91054 Erlangen, Germany
Int J Hyg Environ Health 212:298-309. 2009.... - One-year follow-up of perfluorinated compounds in plasma of German residents from Arnsberg formerly exposed to PFOA-contaminated drinking waterJurgen Holzer
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, 44801 Bochum, Germany
Int J Hyg Environ Health 212:499-504. 2009..The observed decline in PFOA-concentrations indicates a slow elimination in humans. This finding in groups of the general population is in agreement with data on long elimination half-lives observed in occupationally exposed workers... - Penetration of beta-naphthylamine and o-toluidine through human skin in vitroLars Lüersen
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Arch Toxicol 80:644-6. 2006..2 vs. 0.8 h) and in high percentages (54 vs. 50%, respectively, of the applied dose within 24 h). A skin notation is therefore justified for these substances... - Contribution to the evaluation of reference values for PFOA and PFOS in plasma of children and adults from GermanyMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Bochum, Germany
Int J Hyg Environ Health 212:56-60. 2009.... - Acrylamide as environmental noxious agent: a health risk assessment for the general population based on the internal acrylamide burdenBirgitta Kütting
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich Alexander University of Erlangen Nuremberg, Schillerstr 25 29, D 91054 Erlangen, Germany
Int J Hyg Environ Health 212:470-80. 2009..However, carcinogenicity and mutagenicity are possible hazardous health effects for the general population... - Internal phthalate exposure over the last two decades--a retrospective human biomonitoring studyMatthias Wittassek
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Germany
Int J Hyg Environ Health 210:319-33. 2007.... - Influence of industrial sources on children's health--hot spot studies in North Rhine Westphalia, GermanyMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Bochum, Germany
Int J Hyg Environ Health 210:591-9. 2007.... - N-Acetyl-S-(1-carbamoyl-2-hydroxy-ethyl)-L-cysteine (iso-GAMA) a further product of human metabolism of acrylamide: comparison with the simultaneously excreted other mercaptuic acidsEva C Hartmann
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Erlangen, Germany
Arch Toxicol 83:731-4. 2009..We show that dietary doses of acrylamide (AA) cause an overload of detoxification via AAMA and lead to the formation of carcinogenic glycidamide (GA) in the human body... - Subjective complaints in persons under chronic low-dose exposure to lower polychlorinated biphenyls (PCBs)Horst Christoph Broding
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich Alexander Universität Erlangen Nuremberg, Schillerstrasse 25 and 29, 91054 Erlangen, Germany
Int J Hyg Environ Health 211:648-57. 2008..Subjects working in a PCB-contaminated building report more subjective complaints in comparison to non-exposed subjects, but the complaints are not related to current PCB plasma concentrations... - Dermal uptake and excretion of 4,4'-methylenedianiline during rotor blade production in helicopter industry--an intervention studyTobias Weiss
Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine, Friedrich Alexander University Erlangen Nürnberg IPASUM, Schillerstr 25 29, 91054 Erlangen, Germany
Ann Occup Hyg 55:886-92. 2011..The aim of the study presented here was to assess the internal dose of MDA and the suitability of various personal protection measures at the workplace... - Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children -- A comparison of two estimation models based on urinary DEHP metabolite levelsMatthias Wittassek
Institute and Outpatient Clinic of Occupational, Social and Enironmental Medicine, University of Erlangen Nuremberg, Germany
Int J Hyg Environ Health 210:35-42. 2007..Younger children seem to be more severely burdened, which may be due to a higher food consumption related to their bw, mouthing behaviour and/or playing near the ground... - Development and verification of a toxicokinetic model of polychlorinated biphenyl elimination in persons working in a contaminated buildingHorst Christoph Broding
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich Alexander Universität Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Chemosphere 68:1427-34. 2007..Despite a worldwide reduction, environmental exposure remains an issue; the assessment of an individual's level of exposure at a given time in retrospect requires valid toxicokinetic modeling of the different PCB congeners... - New reference value and the background exposure for the PAH metabolites 1-hydroxypyrene and 1- and 2-naphthol in urine of the general population in Germany: basis for validation of human biomonitoring data in environmental medicineMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Bochum, Germany
Int J Hyg Environ Health 211:447-53. 2008..Therefore, the commission recommends the following upper margins of background exposures for adult non-smokers: 1-naphthol less than 30 microg/l, 2-naphthol less than 20 microg/l... - 1,2-Dihydroxynaphthalene as biomarker for a naphthalene exposure in humansKatrin Klotz
University of Erlangen Nuremberg, Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Schillerstrasse 25 29, 91054 Erlangen, Germany
Int J Hyg Environ Health 214:110-4. 2011..Seven isomeric dihydroxynaphthalenes (DHN) were examined for their suitability as biomarkers in human biomonitoring and to get insights in human naphthalene metabolism... - Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamideEva C Hartmann
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nurnberg, Schillerstr 25 29, 91054, Erlangen, Germany
Arch Toxicol 85:601-6. 2011.... - Human biomonitoring studies in North Rhine-Westphalia, GermanyMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Universitatsstrasse 150, 44801 Bochum, Germany
Int J Hyg Environ Health 210:307-18. 2007..More recent studies suggest that there still is an increased internal exposure to metals, PAH and DNA damaging agents in children and women living very close to industrial sources... 
Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate-contaminated drinking waterJurgen Holzer
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Germany
Environ Health Perspect 116:651-7. 2008..40,000 residents in Arnsberg, Germany, had been exposed to drinking water contaminated with perfluorinated compounds (PFCs). Internal exposure of the residents of Arnsberg to six PFCs was assessed in comparison with reference areas...- Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicineThomas Schettgen
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, , Schillerstrasse 25/29, D-91054 Erlangen, Germany
Toxicol Lett 134:65-70. 2002..6 microg/l) in non-smokers compared with 89 pmol/g globin (or 2.4 microg/l) in smokers. Correlations were found between smoking habits and adduct levels of CEV and AAV... - Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general populationMelanie Isabell Boettcher
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, D-91054 Erlangen, Germany
Mutat Res 580:167-76. 2005..From these results compared to the mercapturic acids, we deduce a steady state for AA uptake, and we demonstrate a higher reactivity of GA in comparison to AA towards haemoglobin compared to glutathione in humans... - A first approach to estimate the internal exposure to acrylamide in smoking and non-smoking adults from GermanyThomas Schettgen
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, , Schillerstrasse 25/29, D-91054 Erlangen, Germany
Int J Hyg Environ Health 206:9-14. 2003..6 x 10(-3). Our results confirm a body burden to AA even in persons from the non-smoking general population in Germany that is most probably caused by dietary uptake. Smoking habits considerably contribute to the level of this adduct... - Reassessment of critical lead effects by the German Human Biomonitoring Commission results in suspension of the human biomonitoring values (HBM I and HBM II) for lead in blood of children and adultsMichael Wilhelm
Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Germany
Int J Hyg Environ Health 213:265-9. 2010..We conclude that any setting of an "effect threshold" for blood lead levels would be arbitrary and therefore unjustified. As a consequence the Commission suspends the HBM values for lead in blood of children and adults... - Determination of haemoglobin adducts of acrylamide and glycidamide in smoking and non-smoking persons of the general populationThomas Schettgen
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-University of Erlangen-Nuremberg, Germany
Int J Hyg Environ Health 207:531-9. 2004..Furthermore, our results might indicate that the dose-response curve for acrylamide is not linear. This would be in line with the results of animal experiments on rodents... - Influence of diet on exposure to acrylamide--reflections on the validity of a questionnaireBirgitta Kütting
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friederich Alexander University, Erlangen Nuremberg, Germany
Ann Nutr Metab 49:173-7. 2005..Acrylamide is a toxic substance classified by the International Agency of Research on Cancer, as well as the Deutsche Forschungsgemeinschaft, as a probable human carcinogen... - Di-n-butylphthalate and butylbenzylphthalate - urinary metabolite levels and estimated daily intakes: pilot study for the German Environmental Survey on childrenHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Erlangen, Germany
J Expo Sci Environ Epidemiol 17:378-87. 2007..For both phthalates and independent of the model, we found increasing daily intakes with decreasing age. Between 25% (creatinine model) and 50% (volume model) of the 2-4-year old children had daily intakes for DnBP above the TDI... - Naphthalene--an environmental and occupational toxicantRalf Preuss
University of Erlangen-Nuremberg, Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Schillerstrasse 25/29, 91054 Erlangen, Germany
Int Arch Occup Environ Health 76:556-76. 2003..Naphthoquinones play an important role in this context. Their adducts with macromolecules may be the parameters of choice for the estimation of effects to human health... - External and internal exposure to polycyclic aromatic hydrocarbons (PAH) among workers in the production of fire-proof materials - proposal of a biological monitoring guidance valueRalf Preuss
University of Erlangen-Nuremberg, Institute and Outpatient Clinic of Occupational, Social- and Environmental Medicine, Erlangen, Germany
Int J Hyg Environ Health 209:575-80. 2006..The following BMGVs for the non-smokers of this branch of industry are proposed: for 1-hydroxypyrene 18microg/g creatinine and for the sum of hydroxyphenanthrenes 77microg/g creatinine in urine measured at the end of the shift... - Pilot study on the perfluorooctanesulfonate and perfluorooctanoate exposure of the German general populationOliver Midasch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, 91054 Erlangen, Germany
Int J Hyg Environ Health 209:489-96. 2006..The ubiquitous internal exposure of the general population to PFOS and PFOA must lead to further activities primarily regarding clarification of sources, metabolism, pharmacokinetics, and health effects... - Pyrethroid exposure of the general population-is this due to dietThomas Schettgen
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, , Schillerstrasse 25/29, D-91054, Erlangen, Germany
Toxicol Lett 134:141-5. 2002..3 and 0.27 microg/l, respectively. The metabolic pattern found for these samples points out that pyrethroids are probably ingested orally with daily diet... - Current external and internal exposure to naphthalene of workers occupationally exposed to polycyclic aromatic hydrocarbons in different industriesRalf Preuss
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen, Germany
Int Arch Occup Environ Health 78:355-62. 2005.... - Strategic biomonitoring initiatives: moving the science forwardJurgen Angerer
Institute of Occupational, Social, and Environmental Medicine, University of Erlangen, D 91054 Erlangen, Germany
Toxicol Sci 93:3-10. 2006..As efforts and resources are expended to improve the ability to apply biomonitoring exposure data in the risk assessment process, it is equally important to communicate the significance of such data to the public... - Phthalates: metabolism and exposureMatthias Wittassek
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Erlangen, Germany
Int J Androl 31:131-8. 2008..Therefore, the concept of a cumulative TDI value may be more appropriate for the consideration of the overall exposure and the potential human health risks resulting from everyday and simultaneous exposure to several phthalates... - Investigations on permeation of mitomycin C through double layers of natural rubber glovesGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine of the University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Ann Occup Hyg 51:593-600. 2007..However, occupational exposure to antineoplastic drugs should be minimized, since there is insufficient knowledge regarding harmful effects from a long-term exposure to low doses... - Determination of secondary, oxidised di-iso-nonylphthalate (DINP) metabolites in human urine representative for the exposure to commercial DINP plasticizersHolger M Koch
Institut und Poliklinik für Arbeits, Sozial und Umweltmedizin, Schillerstrasse 25 29, 91054 Erlangen, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 847:114-25. 2007..9microg/l OH-MINP, 8.9microg/l oxo-MINP and 16.4microg/l carboxy-MINP. Metabolites strongly correlated with each other over all samples analyzed (R>0.99, p<0.0001)... - Determination of the major mercapturic acids of acrylamide and glycidamide in human urine by LC-ESI-MS/MSMelanie Isabell Boettcher
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25, Erlangen D-91054, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 824:283-94. 2005..The method therefore provides better insight into the metabolism of acrylamide in humans and furthermore supports risk assessments... - Excretion of mercapturic acids of acrylamide and glycidamide in human urine after single oral administration of deuterium-labelled acrylamideMelanie I Boettcher
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, Erlangen 91054, Germany
Arch Toxicol 80:55-61. 2006..Consequently a genotoxic potency of AA mediated by GA could be supposed to be comparable in rats and humans... - Internal exposure of the general population to DEHP and other phthalates--determination of secondary and primary phthalate monoester metabolites in urineHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, Erlangen D-91054, Germany
Environ Res 93:177-85. 2003..0 microg/L, for monoethylphthalate (MEP) 90.2 microg/L and for mono-n-octylphthalate (MOP)<1.0 microg/L (LOQ). These results will help to perform health risk assessments for the phthalate exposure of the general population... - Enhancement of percutaneous penetration of aniline and o-toluidine in vitro using skin barrier creamsGintautas Korinth
Institute and Out Patient Clinic of Occupational, Social and Environmental Medicine, University Erlangen Nuremberg, Schillerstrasse 25 29, D 91054 Erlangen, Germany
Toxicol In Vitro 22:812-8. 2008..The efficacy of skin creams to protect the percutaneous penetration of aromatic amines is not confirmed by our own experiments... - Evidence for increased internal exposure to lower chlorinated polychlorinated biphenyls (PCB) in pupils attending a contaminated schoolBernhard Liebl
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine of the University of Erlangen Nuremberg, Germany
Int J Hyg Environ Health 207:315-24. 2004..Compared to background levels the detected excess body burden was very low indicating no additional health risk. Exposure was not associated to any specific subjective complaints... - An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general populationHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen, Erlangen, Germany
Int J Hyg Environ Health 206:77-83. 2003..The transgressions of the TDI and RfD for DEHP are accompanied by considerable ubiquitous exposures to DnBP and BbzP, two phthalates under scrutiny for similar toxicological mechanisms... - Internal exposure of nursery-school children and their parents and teachers to di(2-ethylhexyl)phthalate (DEHP)Holger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstr. 25/29, D-91054 Erlangen, Germany
Int J Hyg Environ Health 207:15-22. 2004..To date no information on the biological activity and toxicity of oxidative metabolites of DEHP is available. Since these are the major metabolites of DEHP toxicological data on these metabolites is urgently needed... - Pilot study on the naphthalene exposure of German adults and children by means of urinary 1- and 2-naphthol levelsRalf Preuss
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Erlangen, Germany
Int J Hyg Environ Health 207:441-5. 2004..2 microg/g creatinine (non-smoking adults) and 23.5 microg/g creatinine (young children). It is concluded that 1- and 2-naphthol levels in urine are suitable for human biomonitoring of the naphthalene exposure in environmental medicine... - Analysis of ethenoguanine adducts in human urine using high performance liquid chromatography-tandem mass spectrometryLuis Mariano Gonzalez-Reche
Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Friedrich-Alexander University Erlangen-Nuremberg, Schillerstr. 25, D-91054 Erlangen, Germany
Toxicol Lett 134:71-7. 2002..The background level of the general population has to be taken into account, especially in the investigation of persons occupationally exposed to etheno-adduct forming chemicals... - Determination of DMF modified DNA base N4-methylcarbamoylcytosine in human urine using off-line sample clean-up, two-dimensional LC and ESI-MS/MS detectionKristina Hennebrüder
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, D 91054 Erlangen, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 822:124-32. 2005..In 10 out of 32 urine samples of occupationally to DMF exposed subjects NMC-C could be detected. The concentrations ranged up to 172 ng/L (1023 pmol/L) with a 95th percentile of 121 ng/L (720 pmol/L)... - Quantification of two urinary metabolites of organophosphorus flame retardants by solid-phase extraction and gas chromatography-tandem mass spectrometryBirgit Karin Schindler
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen Nuremberg, Schillerstrasse 25 29, 91054 Erlangen, Germany
Anal Bioanal Chem 395:1167-71. 2009..Twelve percent of the urine samples analysed tested positive for BCPP at concentrations from below the limit of detection to 0.85 microg/l; one sample contained 0.26 microg/l DBP... - Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalateHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054, Erlangen, Germany
Int Arch Occup Environ Health 78:223-9. 2005..Correlation of internal MnBP with MBzP exposure points to common sources of exposure for both phthalates. DnBP exposure seems, at least in part, to be connected with the use of body/skin care products and certain medications... - Di(2-ethylhexyl)phthalate (DEHP) exposure of voluntary plasma and platelet donorsHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen, Germany
Int J Hyg Environ Health 208:489-98. 2005..At present, discontinuous-flow devices should be preferred to avert conceivable health risks from plateletpheresis donors. Strategies to avoid DEHP exposure of donors during apheresis need to be developed... - New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHPHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054, Erlangen, Germany
Arch Toxicol 79:367-76. 2005..All secondary metabolites are unsusceptible to contamination. Furthermore, there are strong hints that the secondary oxidised DEHP metabolites-not DEHP or MEHP-are the ultimate developmental toxicants... - Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHPHolger M Koch
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25/29, 91054 Erlangen, Germany
Arch Toxicol 78:123-30. 2004..0 to 9.3. The excretion ratio of 5OH-MEHP to 5oxo-MEHP remained constant through time at 1.7 in the mean. After 44 h, 47% of the DEHP dose was excreted in urine, comprising MEHP (7.3%), 5OH-MEHP (24.7%) and 5oxo-MEHP (14.9%)... - Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometryRalf Preuss
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Schillerstrasse 25, D-91054 Erlangen, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 816:269-80. 2005..It will help to further explore the human metabolism of DEHP-an occupational and environmental toxicant of great concern... - Simultaneous determination of various aromatic amines and metabolites of aromatic nitro compounds in urine for low level exposure using gas chromatography-mass spectrometryTobias Weiss
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, , Schillerstrasse 25, D-91054 Erlangen, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 778:179-92. 2002..05 microg/l; 0.12 microg/l). We did not detect alpha- or beta-naphtylamine, 4-aminobiphenyl or metabolites of explosives in the samples...