Research Topics
| Josef AltenbuchnerSummaryAffiliation: University of Stuttgart Country: Germany Publications
| Collaborators
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Detail Information
Publications
Characterization of a mannose utilization system in Bacillus subtilisTianqi Sun
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
J Bacteriol 192:2128-39. 2010..subtilis CCR system. Only in the double mutant with an HPr Ser46Ala mutation and a crh knockout mutation was CCR strongly reduced. In contrast, P(manR) and P(manP) were not inducible in a ccpA deletion mutant...
Regulation of mtl operon promoter of Bacillus subtilis: requirements of its use in expression vectorsKambiz Morabbi Heravi
Institut für Industrielle Genetik, Universitat Stuttgart, Germany
Microb Cell Fact 10:83. 2011..In this study, we investigated the regulation of the mtl genes in order to identify the elements needed to construct a strong mannitol inducible expression system in B. subtilis...
Construction of a dual-tag system for gene expression, protein affinity purification and fusion protein processingHassan Motejadded
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
Biotechnol Lett 31:543-9. 2009..After proteolytic cleavage the products were applied to a Ni-NTA column to remove protease and tags. Pure eGFP protein was obtained in the flow-through of the column in a yield of around 35% of the crude cell extract...
Self-inducible Bacillus subtilis expression system for reliable and inexpensive protein production by high-cell-density fermentationMarian Wenzel
Institut für Industrielle Genetik, Universitat Stuttgart, Stuttgart, Germany
Appl Environ Microbiol 77:6419-25. 2011..6%. The novel B. subtilis self-induction system thus makes a considerable contribution to improving product yield and reducing the costs associated with its technical application...
Biosynthesis of zeaxanthin in recombinant Pseudomonas putidaHolger Beuttler
Institute of Technical Biochemistry, Universitaet Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
Appl Microbiol Biotechnol 89:1137-47. 2011..Particularly, the addition of lecithin during cell cultivation increased volumetric productivity of Pseudomonas putida by a factor of 4.7 (51 mg/l vs. 239 mg/l)...
The Escherichia coli rhamnose promoter rhaP(BAD) is in Pseudomonas putida KT2440 independent of Crp-cAMP activationMarcel Jeske
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569, Stuttgart, Germany
Appl Microbiol Biotechnol 85:1923-33. 2010..Other global regulators like Crc, PtsN, and CyoB had no or minor effects on rhamnose-induced eGFP expression. Therefore, this expression system may also be generally useful for Pseudomonas and other gamma-proteobacteria...
Characterization of the tyrosine recombinase MrpA encoded by the Streptomyces coelicolor A3(2) plasmid SCP2*Lydia Warth
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
Arch Microbiol 193:187-200. 2011..The results define MrpA as a new site-specific tyrosine recombinase that acts with mrpS. In addition, we suggest that Y354 provides the nucleophile for DNA cleavage during recombination...
Optimization of an E. coli L-rhamnose-inducible expression vector: test of various genetic module combinationsAngelika Wegerer
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
BMC Biotechnol 8:2. 2008..A capable expression vector is mainly characterized by its production efficiency, stability and induction response. These features can be influenced by a variation of modifications and versatile genetic modules...
Development of a method for markerless gene deletion in Pseudomonas putidaNadja Graf
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
Appl Environ Microbiol 77:5549-52. 2011..The genes were efficiently disrupted and left a markerless chromosomal in-frame deletion...
Degradation of alkyl methyl ketones by Pseudomonas veronii MEK700Christina Onaca
Institut für Industrielle Genetik, Universitat Stuttgart, Allmandring 31, 70569 Stuttgart, Germany
J Bacteriol 189:3759-67. 2007..coli and purified by immobilized metal affinity chromatography. The protein exhibited high esterase activity towards short chain esters like ethyl acetate and 4-nitrophenyl acetate...
Cloning of the netropsin resistance genes from Streptomyces flavopersicus NRRL 2820Tina Stumpp
, , Allmandring 31, 70569 Stuttgart, Germany
J Basic Microbiol 45:355-62. 2005..Deletion analysis showed that both proteins are necessary for netropsin resistance indicating that the proteins form a heterodimeric ABC-transporter exporting netropsin...
Simultaneous expression of an arylacetonitrilase from Pseudomonas fluorescens and a (S)-oxynitrilase from Manihot esculenta in Pichia pastoris for the synthesis of (S)-mandelic acidSven Rustler
Institut fur Mikrobiologie, Universitat Stuttgart, Allmandring 31, Stuttgart, Germany
Appl Microbiol Biotechnol 80:87-97. 2008..The chiral analysis of the products formed revealed a high enantiomeric excess for the (S)-enantiomers...
Streptomyces coelicolor A3(2) plasmid SCP2*: deductions from the complete sequenceIris Haug
, , Allmandring 31, 70569 Stuttgart, Germany
Microbiology 149:505-13. 2003..IS1648 belongs to the IS3 family of insertion sequences. The second element, Tn5417, shows the highest similarity to the Tn4811 element located in the terminal inverted repeats of the Streptomyces lividans chromosome...
