Miguel Angel Alejandre Alcazar
Affiliation: University of Cologne
Alejandre Alcázar M, Morty R, Lendzian L, Vohlen C, Oestreicher I, Plank C, et al
. Inhibition of TGF-? signaling and decreased apoptosis in IUGR-associated lung disease in rats. PLoS ONE. 2011;6:e26371 pubmed publisher
..Taken together, these data demonstrate a significant impact of IUGR on lung development and function and suggest that attenuated TGF-? signaling may contribute to the pathological processes of IUGR-associated lung disease. ..
AlcÃ¡zar M, Dinger K, Rother E, Ã–streicher I, Vohlen C, Plank C, et al
. Prevention of early postnatal hyperalimentation protects against activation of transforming growth factor-Î²/bone morphogenetic protein and interleukin-6 signaling in rat lungs after intrauterine growth restriction. J Nutr. 2014;144:1943-51 pubmed publisher
Dinger K, Mohr J, Vohlen C, Hirani D, Hucklenbruch Rother E, Ensenauer R, et al
. Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes. J Vis Exp. 2018;: pubmed publisher
..Therefore, a standardized methodology to study molecular mechanisms and the effect of novel treatments is essential. ..
Alcazar M, Boehler E, Rother E, Amann K, Vohlen C, von Horsten S, et al
. Early postnatal hyperalimentation impairs renal function via SOCS-3 mediated renal postreceptor leptin resistance. Endocrinology. 2012;153:1397-410 pubmed publisher
Thangaratnarajah C, Dinger K, Vohlen C, Klaudt C, Nawabi J, López García E, et al
. Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction. Am J Physiol Lung Cell Mol Physiol. 2017;313:L491-L506 pubmed publisher
..These new insights in pulmonary neuroimmune interaction offer potential strategies to enable lung growth. ..