Affiliation: University of Giessen
Kupke A, Becker S, Wewetzer K, Ahlemeyer B, Eickmann M, Herden C. Intranasal Borna Disease Virus (BoDV-1) Infection: Insights into Initial Steps and Potential Contagiosity. Int J Mol Sci. 2019;20: pubmed publisher
..Thus, this study provides important insights into the transmission of neurotropic viral infections with a zoonotic potential. ..
Ahlemeyer B, Baumgart Vogt E. Optimized protocols for the simultaneous preparation of primary neuronal cultures of the neocortex, hippocampus and cerebellum from individual newborn (P0.5) C57Bl/6J mice. J Neurosci Methods. 2005;149:110-20 pubmed
..Cytosine arabinofuranoside (AraC) treatment reduced the percentage of astrocytes only significantly in hippocampal cultures, however, increased the percentage of apoptotic neurons in hippocampal and cortical cultures. ..
Ahlemeyer B, Kehr K, Richter E, Hirz M, Baumgart Vogt E, Herden C. Phenotype, differentiation, and function differ in rat and mouse neocortical astrocytes cultured under the same conditions. J Neurosci Methods. 2013;212:156-64 pubmed publisher
..This finding should be taken into account when long-lasting glial reaction patterns are being studied. ..
Ahlemeyer B, Vogt J, Michel V, Hahn Kohlberger P, Baumgart Vogt E. Microporation is an efficient method for siRNA-induced knockdown of PEX5 in HepG2 cells: evaluation of the transfection efficiency, the PEX5 mRNA and protein levels and induction of peroxisomal deficiency. Histochem Cell Biol. 2014;142:577-91 pubmed publisher
..We succeeded to transiently knockdown PEX5 mRNA and its protein level leading to functional consequences similar as observed in peroxisome deficiencies. ..
Ahlemeyer B, Gottwald M, Baumgart Vogt E. Deletion of a single allele of the Pex11? gene is sufficient to cause oxidative stress, delayed differentiation and neuronal death in mouse brain. Dis Model Mech. 2012;5:125-40 pubmed publisher
..Our data might lead to the reconsideration of the clinical treatment of PBDs and the common way of using knockout mouse models for studying autosomal recessive diseases. ..