Michael Adamzik

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS
    M Adamzik
    Institut für Pharmakogenetik, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Eur Respir J 29:482-8. 2007
  2. ncbi request reprint Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 104:168-72. 2007
  3. doi request reprint The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme
    Nicolai El Hindy
    Department of Neurosurgery, University Duisburg Essen and University Hospital Essen, Essen, Germany
    J Surg Oncol 108:492-8. 2013
  4. doi request reprint Association of the CC genotype of the regulatory BCL2 promoter polymorphism (-938C>A) with better 2-year survival in patients with glioblastoma multiforme
    Nicolai El Hindy
    Department of Neurosurgery, Medical Faculty, University of Duisburg Essen, Essen, Germany
    J Neurosurg 114:1631-9. 2011
  5. doi request reprint Posttonsillectomy hemorrhage: blame on surgeons or genes?
    Diana Arweiler-Harbeck
    Department of Otorhinolaryngology, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    Laryngoscope 120:1784-7. 2010
  6. doi request reprint A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Basic Res Cardiol 103:598-610. 2008
  7. ncbi request reprint Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated
    Katharina Rump
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen and Universität Duisburg Essen, and Institut für Pharmakogenetik, Universitätsklinikum Essen and Universität Duisburg Essen, Essen, Germany
    Shock 40:430-6. 2013
  8. doi request reprint Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies
    Simon T Schäfer
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen and Universität Duisburg Essen, Essen, Germany
    Anesthesiology 118:1426-36. 2013
  9. doi request reprint Factor V Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndrome
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Crit Care Med 36:1776-9. 2008
  10. doi request reprint Comparison of thrombelastometry with simplified acute physiology score II and sequential organ failure assessment scores for the prediction of 30-day survival: a cohort study
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Shock 35:339-42. 2011

Detail Information

Publications25

  1. ncbi request reprint ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS
    M Adamzik
    Institut für Pharmakogenetik, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Eur Respir J 29:482-8. 2007
    ....
  2. ncbi request reprint Intravenous lidocaine after tracheal intubation mitigates bronchoconstriction in patients with asthma
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 104:168-72. 2007
    ..We tested the hypothesis that IV lidocaine attenuates intubation-evoked bronchoconstriction in patients with asthma...
  3. doi request reprint The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme
    Nicolai El Hindy
    Department of Neurosurgery, University Duisburg Essen and University Hospital Essen, Essen, Germany
    J Surg Oncol 108:492-8. 2013
    ..Functional genetic variants in the promoter of AQP1, modifying Aquaporin-1-expression, could be associated with altered survival in patients with GBM...
  4. doi request reprint Association of the CC genotype of the regulatory BCL2 promoter polymorphism (-938C>A) with better 2-year survival in patients with glioblastoma multiforme
    Nicolai El Hindy
    Department of Neurosurgery, Medical Faculty, University of Duisburg Essen, Essen, Germany
    J Neurosurg 114:1631-9. 2011
    ..The authors investigated the role of a common regulatory single-nucleotide polymorphism (-938C>A), which is located in the inhibitory P2 promoter of BCL2...
  5. doi request reprint Posttonsillectomy hemorrhage: blame on surgeons or genes?
    Diana Arweiler-Harbeck
    Department of Otorhinolaryngology, University Hospital of Essen, University of Duisburg Essen, Essen, Germany
    Laryngoscope 120:1784-7. 2010
    ..To investigate whether the insertion/deletion polymorphism (-94ins/delATTG) in the promoter of NF kappa B1 is associated with the risk of bleeding after tonsillectomy...
  6. doi request reprint A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Basic Res Cardiol 103:598-610. 2008
    ..We, therefore, sequenced the human AQP5 promoter to detect novel sequence variants which could impact upon AQP5 expression and contribute to the phenotypic variability of the renin-angiotensin-aldosterone system (RAAS)...
  7. ncbi request reprint Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated
    Katharina Rump
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen and Universität Duisburg Essen, and Institut für Pharmakogenetik, Universitätsklinikum Essen and Universität Duisburg Essen, Essen, Germany
    Shock 40:430-6. 2013
    ..Furthermore, neither terbutaline nor cAMP mitigated the LPS-evoked change of AQP1 and AQP5 expression. ..
  8. doi request reprint Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies
    Simon T Schäfer
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen and Universität Duisburg Essen, Essen, Germany
    Anesthesiology 118:1426-36. 2013
    ..Furthermore, we tested that lipopolysaccharide administration increases HIF-1α mRNA and protein in naive and endotoxin-tolerant monocytes...
  9. doi request reprint Factor V Leiden mutation is associated with improved 30-day survival in patients with acute respiratory distress syndrome
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Crit Care Med 36:1776-9. 2008
    ..The aim of this study was to investigate whether the factor V Leiden mutation (Arg506Gln) is associated with altered severity and/or mortality in acute respiratory distress syndrome...
  10. doi request reprint Comparison of thrombelastometry with simplified acute physiology score II and sequential organ failure assessment scores for the prediction of 30-day survival: a cohort study
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Shock 35:339-42. 2011
    ..01; odds ratio, 4.1), respectively, emphasizing the importance of the coagulation system in sepsis...
  11. doi request reprint Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patients
    Nicole Lambertz
    Department of Neurosurgery, Westdeutsches Tumorzentrum WTZ, University Hospital Essen, Hufelandstr 55, 45147, Essen, Germany
    J Neurooncol 112:297-305. 2013
    ..The intensity of edema correlates with the AQP5 A(-1364)C genotype. This suggests AQP5 as an interesting new candidate involved in peritumoral brain edema in meningioma patients...
  12. doi request reprint The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 118:123-33. 2013
    ....
  13. ncbi request reprint Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme
    Nicolai El Hindy
    Department of Neurosurgery, University Hospital, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    J Cancer Res Clin Oncol 136:1423-9. 2010
    ..We investigated potential associations of GNB3 genotypes with survival of patients with glioblastoma multiforme (GBM)...
  14. doi request reprint Aquaporin 5 gene promoter--1364A/C polymorphism associated with 30-day survival in severe sepsis
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Anesthesiology 114:912-7. 2011
    ..Therefore, we tested the hypothesis that the AQP5 promoter -1364A/C polymorphism is associated with increased 30-day survival in severe sepsis...
  15. pmc Comparison of thromboelastometry with procalcitonin, interleukin 6, and C-reactive protein as diagnostic tests for severe sepsis in critically ill adults
    Michael Adamzik
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen und Universität Duisburg Essen, Hufelandstr, 55, 45130 Essen, Germany
    Crit Care 14:R178. 2010
    ..We investigated whether thromboelastometry variables are suitable as biomarkers for severe sepsis in critically ill adults...
  16. ncbi request reprint An increased alveolar CD4 + CD25 + Foxp3 + T-regulatory cell ratio in acute respiratory distress syndrome is associated with increased 30-day mortality
    Michael Adamzik
    Klinik für Anästhesiologie and Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Intensive Care Med 39:1743-51. 2013
    ....
  17. ncbi request reprint Insertion/deletion polymorphism in the promoter of NFKB1 influences severity but not mortality of acute respiratory distress syndrome
    Michael Adamzik
    Institut für Pharmakogenetik, University Hospital Essen, University of Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany
    Intensive Care Med 33:1199-203. 2007
    ..This study investigated whether the insertion/deletion polymorphism in the promoter of NFKB1 is associated with severity and/or mortality in ARDS...
  18. doi request reprint A novel functional haplotype in the human GNAS gene alters Galphas expression, responsiveness to beta-adrenoceptor stimulation, and peri-operative cardiac performance
    Ulrich H Frey
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, D 45122 Essen, Germany
    Eur Heart J 30:1402-10. 2009
    ..We tested whether functional single nucleotide polymorphisms (SNPs) in the human Galphas (GNAS) gene modulate Galphas expression and assessed functional consequences...
  19. doi request reprint Prognostic relevance of the AQP5 -1364C>A polymorphism in primary breast cancer
    Sabine Kasimir-Bauer
    Klinik fur Frauenheilkunde und Geburtshilfe, Universitatsklinikum Essen, Hufelandstr 55, D 45122 Essen, Germany
    Mol Med Report 2:645-50. 2009
    ..Further investigations must include more than one AQP as well as factors promoting angiogenesis to elucidate the different modes of tumor cell dissemination...
  20. pmc Quantification of regulatory T cells in septic patients by real-time PCR-based methylation assay and flow cytometry
    Roman Tatura
    Institute of Medical Microbiology, University Hospital Essen, University of Duisburg Essen, Essen, Germany
    PLoS ONE 7:e49962. 2012
    ..Furthermore, QAMA is a reliable method, which is easier to standardize among laboratories and can thus improve reproducibility of Treg cell quantification...
  21. doi request reprint Aquaporin 1 (AQP1) expression is a novel characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomas
    Friedrich Otterbach
    Institute of Pathology and Neuropathology, University Hospital of Essen, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Breast Cancer Res Treat 120:67-76. 2010
    ..Our results strongly suggest that AQP1 expression is a new characteristic feature of a particularly aggressive subgroup of basal-like breast carcinomas...
  22. doi request reprint Darbepoetin alpha, a long-acting erythropoeitin derivate, does not alter LPS evoked myocardial depression and gene expression of Bax, Bcl-Xs, Bcl-XL, Bcl-2, and TNF-alpha
    Peter Brendt
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Shock 31:50-4. 2009
    ..This may suggest cardiac resistance to darbepoetin in LPS-mediated sepsis...
  23. ncbi request reprint Comparison of manual and automated nucleic acid extraction from whole-blood samples
    Kathrin Riemann
    Institute of Pharmacogenetics, University Hospital Essen, Essen, Germany
    J Clin Lab Anal 21:244-8. 2007
    ..No cross-contamination could be detected. While automated DNA extraction requires significantly less hands-on time, it is slightly more expensive than the manual extraction method...
  24. doi request reprint Alveolar extracellular 20S proteasome in patients with acute respiratory distress syndrome
    Stephan Urs Sixt
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, Essen, Germany
    Am J Respir Crit Care Med 179:1098-106. 2009
    ..Repair mechanisms resulting in alveolar protein degradation in acute respiratory distress syndrome (ARDS) are largely unknown...
  25. ncbi request reprint Conservative treatment of tracheal injuries
    Martin Beiderlinden
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Anesth Analg 100:210-4. 2005
    ....