Affiliation: University of Mainz
Wang X, Ackermann M, Neufurth M, Wang S, Li Q, Feng Q, et al
. Restoration of Impaired Metabolic Energy Balance (ATP Pool) and Tube Formation Potential of Endothelial Cells under "high glucose", Diabetic Conditions by the Bioinorganic Polymer Polyphosphate. Polymers (Basel). 2017;9: pubmed publisher
Muller W, Ackermann M, Neufurth M, Tolba E, Wang S, Feng Q, et al
. A Novel Biomimetic Approach to Repair Enamel Cracks/Carious Damages and to Reseal Dentinal Tubules by Amorphous Polyphosphate. Polymers (Basel). 2017;9: pubmed publisher
Muller W, Relkovic D, Ackermann M, Wang S, Neufurth M, Paravić Radičević A, et al
. Enhancement of Wound Healing in Normal and Diabetic Mice by Topical Application of Amorphous Polyphosphate. Superior Effect of a Host⁻Guest Composite Material Composed of Collagen (Host) and Polyphosphate (Guest). Polymers (Basel). 2017;9: pubmed publisher
..We propose that "Ca⁻polyp-MPs", and particularly the host⁻guest "col/polyp-MPs" are useful for topical treatment of wounds. ..
Muller W, Neufurth M, Wang S, Ackermann M, Muñoz Espí R, Feng Q, et al
. Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ. Int J Mol Sci. 2018;19: pubmed publisher
..The polyP particles are highlighted as genuine, smart, bioinspired nano/micro biomaterials. ..
Ackermann M, Kim Y, Wagner W, Schuppan D, Valenzuela C, Mentzer S, et al
. Effects of nintedanib on the microvascular architecture in a lung fibrosis model. Angiogenesis. 2017;20:359-372 pubmed publisher
..These findings uncover a potential new mode of action of nintedanib that may contribute to its efficacy in idiopathic pulmonary fibrosis. ..
Wang X, Ackermann M, Neufurth M, Wang S, Schröder H, Muller W. Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate. Mar Drugs. 2017;15: pubmed publisher
..Based on our results we propose that amorphous polyP, stabilized onto a collagen matrix, might be a promising component of functionally-active barrier membranes for guided tissue regeneration in medicine and dentistry. ..
Servais A, Valenzuela C, Kienzle A, Ysasi A, Wagner W, Tsuda A, et al
. Functional mechanics of a pectin-based pleural sealant after lung injury. Tissue Eng Part A. 2017;: pubmed
..We conclude that this pectin-based polymer is a strong and nontoxic bioadhesive with the potential for clinical application in the treatment of pleural injuries. ..
Muller W, Wang S, Ackermann M, Neufurth M, Steffen R, Mecja E, et al
. Rebalancing ?-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid ?-Protein Fragment 25-35. Int J Mol Sci. 2017;18: pubmed publisher
..This study contributes to a new routes for a potential therapeutic intervention in Alzheimer's disease pathophysiology. ..
Kristin F, René H, Boontida M, Buraphacheep J, Maximilian A, Johanna M, et al
. Dissolution and dissolution/permeation experiments for predicting systemic exposure following oral administration of the BCS class II drug clarithromycin. Eur J Pharm Sci. 2017;101:211-219 pubmed publisher
..This setup is proposed as best model to predict the in vivo formulation effect. Also, this is the first study to evaluate the impact of the nature of the permeation membrane in dissolution/permeation experiments. ..