M Abele

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. ncbi request reprint Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3
    K Burk
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    J Neurol 246:789-97. 1999
  2. ncbi request reprint In vivo voxel-based morphometry in multiple system atrophy of the cerebellar type
    Karsten Specht
    Medical Centre Bonn, University of Bonn, Bonn, Germany
    Arch Neurol 60:1431-5. 2003
  3. ncbi request reprint Cerebellar ataxia with glutamic acid decarboxylase autoantibodies
    M Abele
    Department of Neurology, University of Tubingen, Germany
    Neurology 52:857-9. 1999
  4. ncbi request reprint Olfactory dysfunction in cerebellar ataxia and multiple system atrophy
    Michael Abele
    Dept of Neurology, University Bonn, Germany
    J Neurol 250:1453-5. 2003
  5. ncbi request reprint Sporadic adult onset ataxia of unknown etiology : a clinical, electrophysiological and imaging study
    M Abele
    Dept of Neurology, University of Bonn, Sigmund Freud Str 25, 53105, Bonn, Germany
    J Neurol 254:1384-9. 2007
  6. ncbi request reprint Health-related quality of life in sporadic adult-onset ataxia
    Michael Abele
    Department of Neurology, University of Bonn, Germany
    Mov Disord 22:348-52. 2007
  7. ncbi request reprint Restless legs syndrome in spinocerebellar ataxia types 1, 2, and 3
    M Abele
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    J Neurol 248:311-4. 2001
  8. ncbi request reprint Nerve conduction studies in multiple system atrophy
    M Abele
    Department of Neurology, University of Tubingen, Germany
    Eur Neurol 43:221-3. 2000
  9. ncbi request reprint Voxel-based morphometry and voxel-based relaxometry in multiple system atrophy-a comparison between clinical subtypes and correlations with clinical parameters
    M Minnerop
    Department of Neurology, University Hospital of Bonn, Bonn, Germany
    Neuroimage 36:1086-95. 2007
  10. ncbi request reprint Cognitive deficits in spinocerebellar ataxia 2
    K Burk
    Department of Neurology, University of Tubingen, Germany
    Brain 122:769-77. 1999

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3
    K Burk
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    J Neurol 246:789-97. 1999
    ..The eye movement disorder of SCA1 patients, however, overlaps with both SCA2 and SCA3...
  2. ncbi request reprint In vivo voxel-based morphometry in multiple system atrophy of the cerebellar type
    Karsten Specht
    Medical Centre Bonn, University of Bonn, Bonn, Germany
    Arch Neurol 60:1431-5. 2003
    ..Multiple system atrophy (MSA) is a sporadic neurodegenerative disease. According to the clinical presentation a parkinsonian type and a cerebellar type (MSA-C) are distinguished...
  3. ncbi request reprint Cerebellar ataxia with glutamic acid decarboxylase autoantibodies
    M Abele
    Department of Neurology, University of Tubingen, Germany
    Neurology 52:857-9. 1999
    ..The authors report a patient with progressive cerebellar ataxia, insulin-dependent diabetes mellitus, and GAD antibodies who responded to i.v. immunoglobulins...
  4. ncbi request reprint Olfactory dysfunction in cerebellar ataxia and multiple system atrophy
    Michael Abele
    Dept of Neurology, University Bonn, Germany
    J Neurol 250:1453-5. 2003
    ..Olfactory dysfunction has been reported in Parkinson's (PD) and Alzheimer's disease (AD)...
  5. ncbi request reprint Sporadic adult onset ataxia of unknown etiology : a clinical, electrophysiological and imaging study
    M Abele
    Dept of Neurology, University of Bonn, Sigmund Freud Str 25, 53105, Bonn, Germany
    J Neurol 254:1384-9. 2007
    ..The sporadic adult onset ataxias of unknown etiology (SAOA) denote the non-hereditary degenerative adult onset ataxias that are distinct from multiple system atrophy (MSA)...
  6. ncbi request reprint Health-related quality of life in sporadic adult-onset ataxia
    Michael Abele
    Department of Neurology, University of Bonn, Germany
    Mov Disord 22:348-52. 2007
    ..The study demonstrates a great impact of SAOA on Hr-QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr-QoL in ataxic patients...
  7. ncbi request reprint Restless legs syndrome in spinocerebellar ataxia types 1, 2, and 3
    M Abele
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    J Neurol 248:311-4. 2001
    ..The probability of developing RLS is related principally to the period over which the CAG repeat mutation exerts its effect and not to CAG repeat length or age of ataxia onset...
  8. ncbi request reprint Nerve conduction studies in multiple system atrophy
    M Abele
    Department of Neurology, University of Tubingen, Germany
    Eur Neurol 43:221-3. 2000
    ..The data provide evidence that the peripheral nervous system is differentially affected in MSA-C and MSA-P...
  9. ncbi request reprint Voxel-based morphometry and voxel-based relaxometry in multiple system atrophy-a comparison between clinical subtypes and correlations with clinical parameters
    M Minnerop
    Department of Neurology, University Hospital of Bonn, Bonn, Germany
    Neuroimage 36:1086-95. 2007
    ..In MSA-C, there was a stronger reduction of gray matter in the basal parts of the cerebellum, of white matter in the brainstem and of the relaxation rate R2 in the cerebellum and brainstem...
  10. ncbi request reprint Cognitive deficits in spinocerebellar ataxia 2
    K Burk
    Department of Neurology, University of Tubingen, Germany
    Brain 122:769-77. 1999
    ..Intellectual impairment should therefore not be interpreted as a secondary effect of progressive motor disability, but represents an important and independent part of the SCA2 phenotype...
  11. ncbi request reprint Prevalence of antigliadin antibodies in ataxia patients
    M Abele
    Department of Neurology, University of Bonn, Germany
    Neurology 60:1674-5. 2003
    ..Although we found a trend toward a higher prevalence of antigliadin antibodies in patients with sporadic ataxia and dominant ataxia, our data do not support an association of ataxia with antigliadin antibodies...
  12. ncbi request reprint The aetiology of sporadic adult-onset ataxia
    M Abele
    Department of Neurology, University of Bonn, Germany
    Brain 125:961-8. 2002
    ..Compared with MSA, disease progression was significantly slower...
  13. pmc Probable multiple system atrophy in a German family
    U Wullner
    Department of Neurology, UKB, Sigmund Freud Strasse, Bonn, Germany
    J Neurol Neurosurg Psychiatry 75:924-5. 2004
    ..The patients presented initially with either parkinsonian or cerebellar signs, and developed severe autonomic failure and typical atrophy of the brain stem and cerebellum in the course of the disease...
  14. ncbi request reprint L-carnitine and creatine in Friedreich's ataxia. A randomized, placebo-controlled crossover trial
    L Schols
    Centre of Neurology and Hertie Institute for Clinical Brain Research, University of Tubingen, Germany
    J Neural Transm 112:789-96. 2005
    ..06, F-test). Ataxia rating scale and echocardiographic parameters remained unchanged. Creatine had no effect in FA patients. L-carnitine is a promising substance for the treatment of FA patients, and larger trials are warranted...
  15. ncbi request reprint Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease
    U Wullner
    Department of Neurology, UKB, Bonn, Germany
    J Neural Transm 114:1161-5. 2007
    ..Thus asymmetry of symptoms, tremor at rest and a positive response to levodopa are not as specific for idiopathic PD as believed previously. Patients with SCA3 may present with the clinical features of MSA...
  16. ncbi request reprint Bright light therapy in Parkinson's disease: a pilot study
    Sebastian Paus
    Department of Neurology, University of Bonn, Bonn, Germany
    Mov Disord 22:1495-8. 2007
    ..It was very well tolerated. Follow up studies in more advanced patient populations employing longer treatment durations are warranted...
  17. ncbi request reprint Dopamine transporter positron emission tomography in spinocerebellar ataxias type 1, 2, 3, and 6
    Ullrich Wullner
    Department of Neurology, University of Bonn, Bonn, Germany
    Arch Neurol 62:1280-5. 2005
    ....
  18. ncbi request reprint REM sleep behavioral disorder in pure autonomic failure (PAF)
    Anja Weyer
    Department of Neurology, University Hospital Bonn, Germany
    Neurology 66:608-9. 2006
  19. ncbi request reprint Health-related quality of life in multiple system atrophy
    Anette Schrag
    Department of Clinical Neurosciences, Royal Free and University College Medical School, London, United Kingdom
    Mov Disord 21:809-15. 2006
    ....
  20. ncbi request reprint Progression of multiple system atrophy (MSA): a prospective natural history study by the European MSA Study Group (EMSA SG)
    Felix Geser
    Clinical Department of Neurology, Innsbruck Medical University, Austria
    Mov Disord 21:179-86. 2006
    ..Our data contribute to the ongoing validation process of UMSARS, and they facilitate the planning and implementation of future neuroprotective intervention trials...
  21. doi request reprint Red flags for multiple system atrophy
    Martin Köllensperger
    Section for Clinical Neurobiology, Department of Neurology, Innsbruck Medical University, Austria
    Mov Disord 23:1093-9. 2008
    ..9 (+/-7.0) months earlier than with the Consensus criteria alone. We propose a combination of two out of six red flag categories as additional diagnostic criteria for probable MSA-P...
  22. ncbi request reprint Saccade velocity is controlled by polyglutamine size in spinocerebellar ataxia 2
    Luis Velázquez-Perez
    Clínica para la Investigación y Rehabilitación de las Ataxias Hereditarias, Holguin, Cuba
    Ann Neurol 56:444-7. 2004
    ..Saccade velocity thus is a sensitive, quite specific, and objective endophenotype, useful to search polyglutamine modifier genes...
  23. ncbi request reprint New mutations in protein kinase Cgamma associated with spinocerebellar ataxia type 14
    Stephan Klebe
    Institut National de la Sante et de la Recherche Médicale U679 formerly U289 and Institut Fédératif de Recherche en Neurosciences, Paris, France
    Ann Neurol 58:720-9. 2005
    ..SCA14 represented only 1.5% (7/454) of French ADCA families but none of the German families. It should, however, be considered in patients with slowly progressive ADCA, particularly when myoclonus and cognitive impairment are present...
  24. ncbi request reprint Spectral analysis of heart rate variability in multiple system atrophy and unexplained sporadic ataxia
    Michael Abele
    J Neurol 251:894-5. 2004
  25. ncbi request reprint Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients
    Anja Weyer
    Department of Neurology, University Hospital of Bonn, Bonn, Germany
    Mov Disord 22:1633-7. 2007
    ..63, P<0.0001) and UHDRS-IV (r=-0.62, P<0.0001), but only weakly correlated with disease duration (r=0.44, P<0.001). The results suggest that SARA is a reliable and valid measure of ataxia in non-SCA ataxia patients...