D Stengel

..More than 100 countries around the world will kick off the first global Decade of Action for Road Safety 2011-2020, a decade that we believe can make a change!..

..Finally, RCTs should be conducted, conditional to the presumed level of innovation of a new implant, and supplemented by data from registries to fully determine the utility, value, and safety of the intervention...

..We sought to determine the accuracy of this method, focusing on the reliability of negative results...

..Pedestrians are at a high risk for crash and injury. This study aims at comparing data from real world crashes with data gathered from experimental settings...

....

..The objective of this study is to determine whether pinning of ACL grafts reduces residual anterior laxity six months after surgery as compared to screw fixation...

..There are no evidence-based guidelines on this matter, and little is known on surgeons' practice and perceived effectiveness of implant removal in different clinical settings...

..There is, however, no systematic approach to the available scientific evidence allowing for a critical appraisal of their benefits and risks...

..49) and slight to fair in phase 3 (kappa=0.23). Retest reliability ranged from 51% to 91%. Doctors give priority to only a small part of the information available in deciding for or against a particular intervention...

..To study whether compliance with methodological standards affected the reported accuracy of screening ultrasonography (US) for trauma...

..In addition, triage criteria need to be refined to increase specificity and reduce the number of unnecessary scans...

..How precise and reliable is ultrasonography as a primary tool for injury assessment in blunt abdominal trauma?..

..Compared to literature data, robot-assisted ACL reconstruction with BTB grafts may lead to higher knee stability, but poorer functional outcomes. The immense additional efforts with the procedure did not pay off in a benefit to patients...

..The researcher's essential graphical toolbox should contain histograms, bar charts (always with measures of error), box-and-whiskers plots, scatter plots and forest plots...

..Individual studies have had conflicting results, however. We examined multiple studies in an attempt to determine whether early sCD62L concentrations are predictive of major complications after severe trauma...

..Considering important arguments raised by both conventional and laparoscopic surgeons, we set out to explore other sources of variability across individual studies...

..The objective of this study was to determine the robustness of soluble L-selectin, correcting for a broad spectrum of physiological variables...

..The observed heterogeneity among patient populations and medical and surgical treatment concepts preclude reliable inferences from the available data...

..It must be emphasized that these designs will require a similarly rigorous planning (i.e., study protocols, ethics, sample size considerations) and analysis of the results...

..To develop a clinically and methodologically sound approach to diagnostic meta-analysis...

..We hypothesized that a liberal pan-scan policy is mainly an indicator of enhanced process quality of emergency care that may lead to improved survival regardless of the actual use of the method...

..43). Thus, in case of a 35% prevalence, the post-test probability has to estimated at 19%. Emergency ultrasound provides high specificity but insufficient sensitivity to reliably rule out intraabdominal injury...

..The purpose of the present study was to determine whether the introduction of a handheld computer could improve both the quantitative and qualitative aspects of medical records...

..We found homogeneous results about hospital mortality. Between 2551 and 821 TKA must be performed by high-volume rather than by low-volume providers to prevent 1 extra death. Absolute event rates are notably small...

..Outcomes research investigates both the desirable and adverse effects of medical and surgical interventions under day-to-day conditions...

..There is evidence that dose reduction from 50 to 40 mg/m(2) reduces the incidence of PPE without compromising cytotoxic activity. We set out to investigate whether biweekly application further improves the therapeutic index of PLD...

..Furthermore, we investigated whether age itself or age-associated comorbidity causes an unfavorable prognostic effect...

..Therefore this article presents the"DocStop Initiative" for medical care on the road, an initiative that runs an international network of care providers (http://www.docstop-online.eu)...

..This article is considered a wake-up call for trauma, orthopaedic, and emergency surgeons in high-income countries to join the global community in fighting the neglected yet potentially curable epidemic named road traffic injuries...

..2%/14.6%). These results suggest that intraoperative 3D Iso-C(3D) imaging provides a high diagnostic reliability. By careful assessment of the images the surgeons receive information which could lead to a change of the operative strategy...

..The objective of this study was to determine the diagnostic value of different ultrasound transducers for the precise detection of visceral damage rather than its surrogates in case of splenic injury...

..To analyse the functional and radiological outcomes of the Bristow-Latarjet procedure in patients with recurrent anterior glenohumeral instability...

..To evaluate the diagnostic effectiveness of dynamic gadodiamide-enhanced MRI in discriminating reparative tissue formation from florid inflammation in patients with chronic osteomyelitis...

....

..We investigated the toxicity profile and therapeutic efficacy of a novel combination regimen, topotecan plus gemcitabine, in a clinical phase II study...

..The present data warrant a larger comparative trial to stabilize effect estimates...

..With further study, we could evaluate the assessment sheet and try to create a classification of the grade of severity as well as prognostic values like return to the former occupation and rehabilitation time...

..The presented trial is currently recruiting patients, with the first results predicted to be available in late 2008...

..Seven of them did not show signs of recurrent infection. CONCLUSION: Adhering to accepted standards of treating osteomyelitis, satisfactory control rates in carpal and metacarpal infection can be achieved while salvaging the hand...

..Accompanying abdominal injuries are frequent in multiply injured patients and are a common cause of death. A search of the literature was performed focusing on key aspects of initial surgical procedures in abdominal injury...

..In both groups of patients there was a significant worsening in the ability of walking after injury, leading to two or more new falls in 24% of DRF and 28% of PHF patients...