T M Tzschentke

Summary

Country: Germany

Publications

  1. ncbi Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues
    T M Tzschentke
    Department of Neuropharmacology, University of Tubingen, Germany
    Prog Neurobiol 56:613-72. 1998
  2. ncbi Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Neurosci Lett 242:114-6. 1998
  3. ncbi The development of cocaine-induced behavioral sensitization is affected by discrete quinolinic acid lesions of the prelimbic medial prefrontal cortex
    T M Tzschentke
    Dept Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse 54 1, 72074 Tubingen, Germany
    Brain Res 795:71-6. 1998
  4. ncbi Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Behav Brain Res 97:115-27. 1998
  5. ncbi Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse 54 1, D 72074 Tubingen, Germany
    Eur J Neurosci 11:4099-109. 1999
  6. ncbi Interactions of MK-801 and GYKI 52466 with morphine and amphetamine in place preference conditioning and behavioural sensitization
    T M Tzschentke
    Zoological Institute, University of Tubingen, Department of Neuropharmacology, Germany
    Behav Brain Res 84:99-107. 1997
  7. ncbi Morphine-induced catalepsy is augmented by NMDA receptor antagonists, but is partially attenuated by an AMPA receptor antagonist
    T M Tzschentke
    Department of Neuropharmacology, University of Tubingen, Germany
    Eur J Pharmacol 295:137-46. 1996
  8. ncbi Effects of amphetamine, morphine and dizocilpine (MK-801) on spontaneous alternation in the 8-arm radial maze
    S M Hölter
    Department of Neuropharmacology, University of Tubingen, Germany
    Behav Brain Res 81:53-9. 1996
  9. ncbi Differential effects of quinolinic acid lesions of the medial prefrontal cortex on the expression of morphine- and dizocilpine- induced behavioural plasticity in the rat
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse, Germany
    Neurosci Lett 283:125-8. 2000
  10. ncbi Differential effects of discrete subarea-specific lesions of the rat medial prefrontal cortex on amphetamine- and cocaine-induced behavioural sensitization
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Cereb Cortex 10:488-98. 2000

Collaborators

Detail Information

Publications12

  1. ncbi Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues
    T M Tzschentke
    Department of Neuropharmacology, University of Tubingen, Germany
    Prog Neurobiol 56:613-72. 1998
    ....
  2. ncbi Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Neurosci Lett 242:114-6. 1998
    ..It is concluded that non-specific disruption of glutamatergic neurotransmission prevents the development of morphine- and amphetamine-induced CPP...
  3. ncbi The development of cocaine-induced behavioral sensitization is affected by discrete quinolinic acid lesions of the prelimbic medial prefrontal cortex
    T M Tzschentke
    Dept Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse 54 1, 72074 Tubingen, Germany
    Brain Res 795:71-6. 1998
    ..It is suggested that this effect might be mediated by the destruction of descending glutamatergic projections from the mPFC to the ventral tegmental area and/or nucleus accumbens...
  4. ncbi Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Behav Brain Res 97:115-27. 1998
    ..This suggests that the mPFC might have a special role in mediating cocaine and MK-801 effects...
  5. ncbi Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse 54 1, D 72074 Tubingen, Germany
    Eur J Neurosci 11:4099-109. 1999
    ..This heterogeneity should be taken into account in future studies addressing the role of the mPFC in drug reward and sensitization...
  6. ncbi Interactions of MK-801 and GYKI 52466 with morphine and amphetamine in place preference conditioning and behavioural sensitization
    T M Tzschentke
    Zoological Institute, University of Tubingen, Department of Neuropharmacology, Germany
    Behav Brain Res 84:99-107. 1997
    ..It can be concluded, that GYKI 52466, like MK-801, can block the expression of a conditioned response, and can also block the expression of sensitized behaviour...
  7. ncbi Morphine-induced catalepsy is augmented by NMDA receptor antagonists, but is partially attenuated by an AMPA receptor antagonist
    T M Tzschentke
    Department of Neuropharmacology, University of Tubingen, Germany
    Eur J Pharmacol 295:137-46. 1996
    ....
  8. ncbi Effects of amphetamine, morphine and dizocilpine (MK-801) on spontaneous alternation in the 8-arm radial maze
    S M Hölter
    Department of Neuropharmacology, University of Tubingen, Germany
    Behav Brain Res 81:53-9. 1996
    ..Analysis of the sequences of arm entries revealed that all drugs induced perseverative locomotor patterns, but the pattern induced by amphetamine and morphine differed qualitatively from the pattern induced by MK-801...
  9. ncbi Differential effects of quinolinic acid lesions of the medial prefrontal cortex on the expression of morphine- and dizocilpine- induced behavioural plasticity in the rat
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstrasse, Germany
    Neurosci Lett 283:125-8. 2000
    ..These results suggest that the expression of behavioural plasticity induced by different drugs is mediated at least in part by different neural substrates...
  10. ncbi Differential effects of discrete subarea-specific lesions of the rat medial prefrontal cortex on amphetamine- and cocaine-induced behavioural sensitization
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Germany
    Cereb Cortex 10:488-98. 2000
    ....
  11. ncbi State-dependent blockade of haloperidol-induced sensitization of catalepsy by MK-801
    W J Schmidt
    University of Tubingen, Department of Neuropharmacology, Zoological Institute, Germany
    Eur J Neurosci 11:3365-8. 1999
    ..These results may be explained in terms of state-dependency effects induced by MK-801. Implications of these findings for the clinical use of NMDA receptor antagonists in the treatment of Parkinson's disease are discussed...
  12. ncbi Memantine does not substantially affect brain stimulation reward: comparison with MK-801
    T M Tzschentke
    Department of Neuropharmacology, Zoological Institute, University of Tubingen, Mohlstr 54 1, 72074, Tubingen, Germany
    Brain Res 845:192-8. 1999
    ..This study shows that memantine failed to substantially influence BSR at low to intermediate doses, suggesting that this substance is likely to be largely devoid of rewarding effects in a therapeutic dose range...