Axel Trautmann

Summary

Country: Germany

Publications

  1. pmc Allergic anaphylaxis due to subcutaneously injected heparin
    Diana Anders
    Department of Dermatology, Venereology, and Allergology, University Hospital of Wurzburg, Josef Schneider Str, 2, Wurzburg, 97080, Germany
    Allergy Asthma Clin Immunol 9:1. 2013
  2. ncbi request reprint [How does eczema arise?]
    Axel Trautmann
    Klinik und Poliklinik für Hautkrankheiten der Universität Würzburg
    J Dtsch Dermatol Ges 1:8-11. 2003
  3. ncbi request reprint Apoptosis and loss of adhesion of bronchial epithelial cells in asthma
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Int Arch Allergy Immunol 138:142-50. 2005
  4. doi request reprint Heparin allergy: delayed-type non-IgE-mediated allergic hypersensitivity to subcutaneous heparin injection
    Axel Trautmann
    Allergy Unit, Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Josef Schneider Strasse 2, Wurzburg 97080, Germany
    Immunol Allergy Clin North Am 29:469-80. 2009
  5. pmc Occupational allergy due to seafood delivery: Case report
    Cornelia S Seitz
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Wurzburg, Germany
    J Occup Med Toxicol 3:11. 2008
  6. doi request reprint The complex clinical picture of side effects to anticoagulation
    Axel Trautmann
    Allergy Unit, Department of Dermatology, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Med Clin North Am 94:821-34, xii-iii. 2010
  7. pmc Human CD8 T cells of the peripheral blood contain a low CD8 expressing cytotoxic/effector subpopulation
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Obere Strasse 22, CH 7270 Davos, Switzerland
    Immunology 108:305-12. 2003
  8. ncbi request reprint T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    J Allergy Clin Immunol 109:329-37. 2002
  9. ncbi request reprint A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epidermis in
    Sven Klunker
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Immunol 171:1078-84. 2003
  10. ncbi request reprint T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Obere Strasse 22, CH 7270 Davos, Switzerland
    FASEB J 17:1026-35. 2003

Collaborators

Detail Information

Publications41

  1. pmc Allergic anaphylaxis due to subcutaneously injected heparin
    Diana Anders
    Department of Dermatology, Venereology, and Allergology, University Hospital of Wurzburg, Josef Schneider Str, 2, Wurzburg, 97080, Germany
    Allergy Asthma Clin Immunol 9:1. 2013
    ..Because these compounds have a completely different molecular structure compared with the heparin-polysaccharides...
  2. ncbi request reprint [How does eczema arise?]
    Axel Trautmann
    Klinik und Poliklinik für Hautkrankheiten der Universität Würzburg
    J Dtsch Dermatol Ges 1:8-11. 2003
    ..Cleavage of adhesion molecules on keratinocytes leads to spongiotic changes. Keratinocytes then activate repair mechanisms, which cause acanthosis and parakeratosis in chronic eczema...
  3. ncbi request reprint Apoptosis and loss of adhesion of bronchial epithelial cells in asthma
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Int Arch Allergy Immunol 138:142-50. 2005
    ..Since EC shedding is a histologic hallmark of asthma, the intercellular junction of EC may be a target of pro-inflammatory cytokines...
  4. doi request reprint Heparin allergy: delayed-type non-IgE-mediated allergic hypersensitivity to subcutaneous heparin injection
    Axel Trautmann
    Allergy Unit, Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Josef Schneider Strasse 2, Wurzburg 97080, Germany
    Immunol Allergy Clin North Am 29:469-80. 2009
    ..Moreover, in case of therapeutic necessity and DTH to heparins, the simple shift from subcutaneous to intravenous heparin administration without prior testing may be justified...
  5. pmc Occupational allergy due to seafood delivery: Case report
    Cornelia S Seitz
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Wurzburg, Germany
    J Occup Med Toxicol 3:11. 2008
    ..However, even in jobs with limited direct exposure, individuals with atopic disposition not using appropriate skin protection are at risk for developing occupational seafood allergy which requires termination of employment...
  6. doi request reprint The complex clinical picture of side effects to anticoagulation
    Axel Trautmann
    Allergy Unit, Department of Dermatology, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Med Clin North Am 94:821-34, xii-iii. 2010
    ..This is in contrast to coumarin-induced skin necrosis, where therapy may be continued or restarted at a lower dose...
  7. pmc Human CD8 T cells of the peripheral blood contain a low CD8 expressing cytotoxic/effector subpopulation
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Obere Strasse 22, CH 7270 Davos, Switzerland
    Immunology 108:305-12. 2003
    ..Therefore, the CD8low population represent a subset of activated CD8 effector T cells, resulting most probably from a continuous and/or balanced immune response to intracellular pathogens...
  8. ncbi request reprint T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    J Allergy Clin Immunol 109:329-37. 2002
    ..Asthma is an inflammatory airway disease associated with an infiltration of T cells and eosinophils, increased levels of pro-inflammatory cytokines, and shedding of bronchial epithelial cells (ECs)...
  9. ncbi request reprint A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epidermis in
    Sven Klunker
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Immunol 171:1078-84. 2003
    ..Keratinocytes undergoing apoptosis in acute eczematous lesions release chemokines that attract more T cells toward the epidermis, which may further augment the inflammation and keratinocyte apoptosis...
  10. ncbi request reprint T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Obere Strasse 22, CH 7270 Davos, Switzerland
    FASEB J 17:1026-35. 2003
    ..These results define a novel mechanism for peripheral Th2 response in atopic diseases...
  11. ncbi request reprint Aminopenicillin-induced exanthema allows treatment with certain cephalosporins or phenoxymethyl penicillin
    Jiri Trcka
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Wurzburg, Germany
    J Antimicrob Chemother 60:107-11. 2007
    ..The aim of the study is to demonstrate that patients with aminopenicillin-induced exanthema may receive specific beta-lactams for future antibiotic therapy...
  12. ncbi request reprint Tolerance to intravenous heparin in patients with delayed-type hypersensitivity to heparins: a prospective study
    Zeno Gaigl
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Br J Haematol 128:389-92. 2005
    ..Therefore, in case of therapeutic necessity, the shift from subcutaneous to intravenous heparin administration is justified...
  13. ncbi request reprint Management of allergy to heparins in postoperative care: subcutaneous allergy and intravenous tolerance
    Cornelia S Seitz
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Germany
    Dermatol Online J 14:4. 2008
    ..Therefore, in cases of delayed-type hypersensitivity to subcutaneously injected heparins, the switch from subcutaneous to intravenous heparin administration may be justified...
  14. doi request reprint Diagnosis of drug hypersensitivity in children and adolescents: discrepancy between physician-based assessment and results of testing
    Cornelia S Seitz
    Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Josef Schneider Strasse 2, Wurzburg, Germany
    Pediatr Allergy Immunol 22:405-10. 2011
    ..However, the diagnostic value of this complex and time-consuming allergologic work-up, especially in children, remains controversial...
  15. ncbi request reprint Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents
    Cornelia S Seitz
    Department of Dermatology, Venerology, and Allergology, University of Wurzburg, Wurzburg, Germany
    Ann Allergy Asthma Immunol 97:698-702. 2006
    ..Other anticonvulsant agents, such as valproic acid, benzodiazepines, and gabapentin, may be prescribed...
  16. ncbi request reprint T cells and effector mechanisms in the pathogenesis of atopic dermatitis
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research, Obere Strasse 22, CH 7270 Davos, Switzerland
    Curr Allergy Asthma Rep 2:1-3. 2002
  17. doi request reprint Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing
    Cornelia S Seitz
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Germany
    Allergol Immunopathol (Madr) 39:193-9. 2011
    ..The aim of this retrospective analysis was to demonstrate results of diagnostic testing in cases of clinically suspected immediate and delayed macrolide hypersensitivity...
  18. doi request reprint Suprabasal spongiosis in acute eczematous dermatitis: cFLIP maintains resistance of basal keratinocytes to T-cell-mediated apoptosis
    Nicole Armbruster
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Wurzburg, Germany
    J Invest Dermatol 129:1696-702. 2009
    ....
  19. doi request reprint Radiocontrast media-associated exanthema: identification of cross-reactivity and tolerability by allergologic testing
    Cornelia S Seitz
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Eur J Radiol 72:167-71. 2009
    ..Delayed-type hypersensitivity to RCM may pose a problem for future radiologic investigations because due to possible immunological cross-reactivity all iodinated RCM are usually avoided...
  20. ncbi request reprint Nonsteroidal anti-inflammatory drug hypersensitivity: fable or reality?
    Barbara Schubert
    Department of Dermatology, University of Wurzburg, Josef Schneider Strasse 2, D 97080 Wurzburg, Germany
    Eur J Dermatol 15:164-7. 2005
    ..Our study demonstrates that oral challenge tests are safe, practical and useful in ruling out NSAID hypersensitivity in approximately 50% of the patients who have previously been labelled as such...
  21. doi request reprint Over- and underestimated parameters in severe Hymenoptera venom-induced anaphylaxis: cardiovascular medication and absence of urticaria/angioedema
    Johanna Stoevesandt
    Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Wurzburg, Germany
    J Allergy Clin Immunol 130:698-704.e1. 2012
    ..Severe anaphylaxis in Hymenoptera venom allergy has been associated with a number of risk factors including elevation of baseline serum tryptase (BST), older age, concomitant diseases, and concurrent medication...
  22. doi request reprint Effector pathways during eczematous dermatitis: where inflammation meets cell death
    Andreas Kerstan
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Germany
    Exp Dermatol 18:893-9. 2009
    ..Further advances will come from identification of the immunoregulatory mechanisms involved in the pathogenesis of eczematous dermatitis. Potential therapeutic interventions are discussed...
  23. doi request reprint Allergy diagnostic testing in clindamycin-induced skin reactions
    Cornelia S Seitz
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Wurzburg, Germany
    Int Arch Allergy Immunol 149:246-50. 2009
    ..The aim of this retrospective analysis was to demonstrate the results of skin and challenge tests in cases of clinically suspected clindamycin allergy...
  24. doi request reprint Vaccination-associated anaphylaxis in adults: diagnostic testing ruling out IgE-mediated vaccine allergy
    Cornelia S Seitz
    Department of Dermatology, University of Wurzburg, Wurzburg, D 97080 Wurzburg, Germany
    Vaccine 27:3885-9. 2009
    ..Therefore, a history of anaphylaxis after vaccination may not be an absolute contraindication for re-vaccination...
  25. pmc Allergy evaluation after emergency treatment: anaphylaxis to the over-the-counter medication clobutinol
    Cornelia S Seitz
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Josef Schneider Strasse 2, D 97080 Wurzburg, Germany
    Emerg Med J 24:e19. 2007
    ....
  26. doi request reprint Wasp venom immunotherapy induces activation and homing of CD4(+)CD25(+) forkhead box protein 3-positive regulatory T cells controlling T(H)1 responses
    Andreas Kerstan
    Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Wurzburg, Germany
    J Allergy Clin Immunol 127:495-501.e1-6. 2011
    ..Despite a growing interest in CD4(+)CD25(+) forkhead box protein 3 (Foxp3)-positive regulatory T (Treg) cells, the fundamental parameters of the activation and homing of these cells during wasp venom immunotherapy (VIT) are largely unknown...
  27. ncbi request reprint Wine anaphylaxis in a German patient: IgE-mediated allergy against a lipid transfer protein of grapes
    Susanne G Schad
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Int Arch Allergy Immunol 136:159-64. 2005
    ..The purpose of this case study was to identify the allergens responsible for severe anaphylactic reactions after consumption of wine, fresh grapes and raisins in a German patient...
  28. ncbi request reprint Eyelid dermatitis due to sodium metabisulfite
    Cornelia S Seitz
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Wurzburg, Germany
    Contact Dermatitis 55:249-50. 2006
  29. doi request reprint Painful wrinkles in the bathtub: association with hyperhidrosis and cystic fibrosis
    Cornelia S Seitz
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Wurzburg, Germany
    Dermatology 216:222-6. 2008
    ....
  30. ncbi request reprint [Granuloma after ear-piercing]
    Zeno Gaigl
    Klinik und Poliklinik für Haut und Geschlechtskrankheiten der Universität Wurzburg
    J Dtsch Dermatol Ges 2:707-9. 2004
  31. doi request reprint Do-it-yourself cement work: the main cause of severe irritant contact dermatitis requiring hospitalization
    Heiko Poppe
    Department of Dermatology, Venereology, and Allergology, University Hospital of Wurzburg, Wurzburg, Germany
    Contact Dermatitis 68:111-5. 2013
    ..In the large majority of cases, dermatitis is mild to moderate, and patients do not need hospitalization. However, some agents or special circumstances may cause severe dermatitis requiring more intensive therapy...
  32. pmc Wine allergy in a wine-growing district: tolerance induction in a patient with allergy to grape lipid-transfer protein
    Susanne G Schad
    From the 1Department of Dermatology and Venereology, University of Rostock, Rostock, Germany 2Division of Allergology, Paul Ehrlich Institut, Langen, Germany 3Department of Dermatology, Venereology, and Allergology, University of Wurzburg, Wurzburg, Germany
    World Allergy Organ J 3:1-5. 2010
    ..An IgE-mediated allergy against a lipid-transfer protein of grapes was the cause of repeated severe anaphylaxis in a patient after consumption of grapes, wine, and raisins...
  33. ncbi request reprint Bullous allergic hypersensitivity to bed bug bites mediated by IgE against salivary nitrophorin
    Martin Leverkus
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    J Invest Dermatol 126:91-6. 2006
    ..lectularius nitrophorin, but not to 37 kDa C. lectularius apyrase. Our data demonstrate that bullous cimicosis may be the late-phase response of an allergic IgE-mediated hypersensitivity to C. lectularius nitrophorin...
  34. doi request reprint Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature
    Cornelia S Seitz
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany cseitz med uni goettingen de
    Dermatology 220:268-73. 2010
    ..However, most RA patients develop leg ulcers due to other pathophysiological factors posing a diagnostic and therapeutic challenge and leading to considerable morbidity...
  35. doi request reprint Pitfall scarring alopecia: favus closely mimicking lichen planus
    Heiko Poppe
    Department of Dermatology, Venereology, and Allergology, University Hospital of Wurzburg, Wurzburg, Germany
    Mycoses 56:382-4. 2013
    ..But mycological investigations revealed that cicatricial alopecia was caused by a specific infection with Trichophyton schoenleinii running a chronic course with minimal skin inflammation...
  36. ncbi request reprint A pickled plum of a problem
    Axel Trautmann
    Department of Dermatology, Venerology and Allergology, University of Wurzburg, Wurzburg, Germany
    Am J Med 120:775-7. 2007
  37. doi request reprint The One-nail Brown Band: Macro- and Micro-morphology
    Lidia M Poppe
    Department of Dermatology, Venereology, and Allergology, University Hospital of Würzburg Josef Schneider Strasse 2, DE 97080 Würzburg, Germany
    Acta Derm Venereol 93:479-80. 2013
    ..Abstract is missing (Letter). ..
  38. pmc The concept of "compartment allergy": prilocaine injected into different skin layers
    Marion Wobser
    Department of Dermatology, Venereology, and Allergology, University of Wuerzburg, Germany
    Allergy Asthma Clin Immunol 7:7. 2011
    ..The term compartment allergy indicates that the route of allergen administration together with the targeted immunologic environment orchestrates on the immunologic outcome: overt T-cell mediated allergy or clinical tolerance...
  39. doi request reprint Uro-dermatological problems of a construction worker: paraaminobenzoic acid as a systemic photosensitizer
    Johanna Stoevesandt
    Department of Dermatology, Venereology and Allergology, University of Wurzburg, Josef Schneider Strasse 2, D 97080 Wurzburg, Germany
    Eur J Dermatol 20:217-9. 2010
    ..In sunscreens, PABA has mostly been abandoned due to its known topical photosensitization properties, but it has not yet been recognized as a systemic photosensitizer...
  40. ncbi request reprint IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis
    Peter Schmid-Grendelmeier
    Swiss Institute of Allergy and Asthma Research, Davos, Switherland
    J Allergy Clin Immunol 115:1068-75. 2005
    ..Autoreactivity of patients with atopic dermatitis (AD) to human proteins has been postulated as a decisive pathogenetic factor for AD...
  41. ncbi request reprint CD95-mediated signals in the skin: going out with an (inflammatory) bang?
    Martin Leverkus
    Laboratory for Experimental Dermatology, Department of Dermatology and Venerology, Otto von Guericke University of Magdeburg, Magdeburg, Germany
    J Invest Dermatol 126:2364-6. 2006
    ..This more pleiotropic function of CD95L as enhancer of inflammation may be equally important to apoptosis induction of keratinocytes, at least in eczema...