Christoph Thorns

Summary

Country: Germany

Publications

  1. ncbi EMMPRIN (CD 174) is expressed in Hodgkin's lymphoma and anaplastic large cell lymphoma. An immunohistochemical study of 60 cases
    Christoph Thorns
    Institute of Pathology, Medical University of Luebeck, Germany
    Anticancer Res 22:1983-6. 2002
  2. ncbi cDNA arrays: gene expression profiles of Hodgkin's disease and anaplastic large cell lymphoma cell lines
    Christoph Thorns
    Department of Pathology, German Consultation and Reference Center for Lymphomas, Medical University of Luebeck, Luebeck, Germany
    Pathol Int 52:578-85. 2002
  3. ncbi Matrix-metalloproteinases in Hodgkin lymphoma
    C Thorns
    Institute of Pathology, University of Luebeck, German Consultation and Reference Centre for Lymphomas, Germany
    Anticancer Res 23:1555-8. 2003
  4. doi miRNA expression profiling in formalin-fixed and paraffin-embedded placental tissue samples from pregnancies with severe preeclampsia
    Frank Noack
    Institute of Pathology, University of Lubeck, Germany
    J Perinat Med 39:267-71. 2011
  5. doi Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
    German Ott
    Institute of Pathology, University of Wurzburg, Wurzburg, Germany
    Blood 116:4916-25. 2010
  6. doi MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas
    Anja Roehle
    Institute for Pathology, University Clinic Schleswig Holstein, Campus Luebeck, Luebeck, Germany
    Br J Haematol 142:732-44. 2008
  7. doi Sarcoma of follicular dendritic cells with features of sinus lining cells--a new subtype of reticulum cell sarcoma?
    Manuela Krokowski
    Department of Pathology, Reference Center for Lymph Node Pathology and Hematopathology, University Hospital of Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Virchows Arch 452:565-70. 2008
  8. ncbi BCL6-translocations affect the phenotype of follicular lymphomas only in the absence of t(14;18)IgH/BCL2
    Wiebke Gollub
    Department of Pathology, University Clinic Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, D 23538 Luebeck, Germany
    Anticancer Res 29:4649-55. 2009
  9. ncbi Gene profiling in anaplastic large-cell lymphoma-derived cell lines with cDNA expression arrays
    Timo Gaiser
    Department of Pathology, Medical University of Luebeck, 23538 Luebeck, Germany
    J Hematother Stem Cell Res 11:423-8. 2002
  10. pmc Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
    Heinz Wolfram Bernd
    Institute of Pathology, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160 D 23538 Lübeck, Germany
    Haematologica 94:1569-80. 2009

Detail Information

Publications17

  1. ncbi EMMPRIN (CD 174) is expressed in Hodgkin's lymphoma and anaplastic large cell lymphoma. An immunohistochemical study of 60 cases
    Christoph Thorns
    Institute of Pathology, Medical University of Luebeck, Germany
    Anticancer Res 22:1983-6. 2002
    ..Whereas TIMP-1 expression is described for high-grade malignant lymphomas and seems to be correlated with unfavourable prognosis, there are no data on the expression of EMMPRIN in malignant lymphoma...
  2. ncbi cDNA arrays: gene expression profiles of Hodgkin's disease and anaplastic large cell lymphoma cell lines
    Christoph Thorns
    Department of Pathology, German Consultation and Reference Center for Lymphomas, Medical University of Luebeck, Luebeck, Germany
    Pathol Int 52:578-85. 2002
    ..Because the expression profiling was performed on cell lines, further studies are needed to clarify the biological significance of the differentially expressed genes...
  3. ncbi Matrix-metalloproteinases in Hodgkin lymphoma
    C Thorns
    Institute of Pathology, University of Luebeck, German Consultation and Reference Centre for Lymphomas, Germany
    Anticancer Res 23:1555-8. 2003
    ..These morphological peculiarities led to the idea that the interaction between tumour cells and bystander cells as well as the extracellular matrix may be important in Hodgkin lymphomas...
  4. doi miRNA expression profiling in formalin-fixed and paraffin-embedded placental tissue samples from pregnancies with severe preeclampsia
    Frank Noack
    Institute of Pathology, University of Lubeck, Germany
    J Perinat Med 39:267-71. 2011
    ..The placenta is considered to play a key role in pathogenesis of preeclampsia. The purpose of this study was to demonstrate deregulation of miRNAs in placentas with preeclampsia using formalin-fixed and paraffin-embedded (FFPE) tissues...
  5. doi Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
    German Ott
    Institute of Pathology, University of Wurzburg, Wurzburg, Germany
    Blood 116:4916-25. 2010
    ....
  6. doi MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas
    Anja Roehle
    Institute for Pathology, University Clinic Schleswig Holstein, Campus Luebeck, Luebeck, Germany
    Br J Haematol 142:732-44. 2008
    ..Finally, eight miRNAs were found to correlate with event-free and overall survival in DLBCL including known tumour suppressors (MIRN21, MIRN127 and MIRN34a) and oncogenes (MIRN195 and MIRNLET7G)...
  7. doi Sarcoma of follicular dendritic cells with features of sinus lining cells--a new subtype of reticulum cell sarcoma?
    Manuela Krokowski
    Department of Pathology, Reference Center for Lymph Node Pathology and Hematopathology, University Hospital of Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Virchows Arch 452:565-70. 2008
    ..Due to the assumed specificity of this antibody, we propose designation of this reticulum cell sarcoma as lymphatic sinus lining cell sarcoma which might finally represent another subtype of reticulum cell sarcomas...
  8. ncbi BCL6-translocations affect the phenotype of follicular lymphomas only in the absence of t(14;18)IgH/BCL2
    Wiebke Gollub
    Department of Pathology, University Clinic Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, D 23538 Luebeck, Germany
    Anticancer Res 29:4649-55. 2009
    ..This study aimed to determine the frequency of BCL2- and BCL6-translocations in FL and to identify morphological and immuno-histochemical features with respect to the presence of BCL2- and BCL6-translocations...
  9. ncbi Gene profiling in anaplastic large-cell lymphoma-derived cell lines with cDNA expression arrays
    Timo Gaiser
    Department of Pathology, Medical University of Luebeck, 23538 Luebeck, Germany
    J Hematother Stem Cell Res 11:423-8. 2002
    ....
  10. pmc Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials
    Heinz Wolfram Bernd
    Institute of Pathology, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160 D 23538 Lübeck, Germany
    Haematologica 94:1569-80. 2009
    ....
  11. ncbi Unlocking pathology archives for microRNA-profiling
    Kai P Hoefig
    Institute for Pathology, UKSH Campus Luebeck, Luebeck, Germany
    Anticancer Res 28:119-23. 2008
    ..A variety of high-throughput screening methods has been developed to identify dysregulated miRNA species in tumours. For retrospective clinical studies formalin-fixed, paraffin-embedded (FFPE) tissue is the most widely used material...
  12. ncbi Basal cell carcinoma with neuroendocrine differentiation arising in a scar: A case report
    Manuela Krokowski
    Department of Pathology, University Hospital of Schleswig Holstein, Campus Luebeck, Germany
    Dermatol Online J 15:4. 2009
    ..Neuroendocrine differentiation was proven by immunohistochemistry and electron microscopy. The simultaneous occurrence of BCC development in a scar and neuroendocrine differentiation is quite rare...
  13. ncbi Application of novel tissue microarrays to investigate expression of tryptase, chymase and KIT protein in placental mast cells
    Frank Noack
    Department of Pathology, University Hospital Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Arch Gynecol Obstet 272:223-8. 2005
    ..Because little is known about the role of mast cells in the placenta, we investigated the number and expression of chymase, tryptase, and KIT protein in placental mast cells using newly developed tissue microarrays...
  14. ncbi Prognostic value of MCM2 immunoreactivity in stage T1 transitional cell carcinoma of the bladder
    Stefan Kruger
    Institute of Pathology, University of Lubeck, Ratzeburger Allee 160, D 23538, Lubeck, Germany
    Eur Urol 43:138-45. 2003
    ..To our knowledge, there are no reports on studies investigating minichromosome maintenance protein 2 (MCM2) expression in bladder carcinomas. Thus, we investigated the prognostic value of MCM2 immunoreactivity in stage T1 bladder tumors...
  15. ncbi Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach
    Christoph Thorns
    Department of Pathology, German Consultation and Reference Center for Lymphomas, University Clinic Schleswig Holstein, Campus Luebeck, Luebeck, Germany
    Genes Chromosomes Cancer 46:37-44. 2007
    ..In conclusion, CGH revealed common genetic events in peripheral T-cell lymphomas as well as peculiar differences between AILT and PTCL-u...
  16. ncbi Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications--a study from the Lunenburg Lymphoma Biomarker Consortium
    Daphne de Jong
    Netherlands Cancer Institute, Amsterdam, The Netherlands
    J Clin Oncol 25:805-12. 2007
    ....
  17. doi Preservation of follicle mantle in follicular lymphoma
    Christoph Thorns
    Leuk Lymphoma 49:166-7. 2008