Friedrich P Thinnes

Summary

Country: Germany

Publications

  1. ncbi request reprint Opening up of plasmalemma type-1 VDAC to form apoptotic "find me signal" pathways is essential in early apoptosis - evidence from the pathogenesis of cystic fibrosis resulting from failure of apoptotic cell clearance followed by sterile inflammation
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 111:439-44. 2014
  2. doi request reprint New findings concerning vertebrate porin II--on the relevance of glycine motifs of type-1 VDAC
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany
    Mol Genet Metab 108:212-24. 2013
  3. doi request reprint Why cancer survivors have a lower risk of Alzheimer disease
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 107:630-1. 2012
  4. doi request reprint On a fully closed state of native human type-1 VDAC enriched in Nonidet P40
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 107:632-3. 2012
  5. doi request reprint Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathway
    Friedrich P Thinnes
    Mol Genet Metab 97:241-3. 2009
  6. doi request reprint Apoptogenic interactions of plasmalemmal type-1 VDAC and Aβ peptides via GxxxG motifs induce Alzheimer's disease - a basic model of apoptosis?
    Friedrich P Thinnes
    Wien Med Wochenschr 161:274-6. 2011

Detail Information

Publications6

  1. ncbi request reprint Opening up of plasmalemma type-1 VDAC to form apoptotic "find me signal" pathways is essential in early apoptosis - evidence from the pathogenesis of cystic fibrosis resulting from failure of apoptotic cell clearance followed by sterile inflammation
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 111:439-44. 2014
    ..Together, type-1 VDAC should be kept as a "find me signal" pathway, which may give way to several classes of such signals. ..
  2. doi request reprint New findings concerning vertebrate porin II--on the relevance of glycine motifs of type-1 VDAC
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany
    Mol Genet Metab 108:212-24. 2013
    ..While elaborating this concept, my focus was at first only on the GxxxG motif at the proximal end of the N-terminal voltage sensor of type-1 VDAC. Here, I include a corresponding sequence stretch on the channel's β-sheet 19, too...
  3. doi request reprint Why cancer survivors have a lower risk of Alzheimer disease
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 107:630-1. 2012
    ..The hypothesis presented can be read as a clue on what in recent literature is referred to as the inverse association of cancer and Alzheimer disease...
  4. doi request reprint On a fully closed state of native human type-1 VDAC enriched in Nonidet P40
    Friedrich P Thinnes
    Baumschulenweg 5, D 37083 Göttingen, Germany Electronic address
    Mol Genet Metab 107:632-3. 2012
    ....
  5. doi request reprint Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathway
    Friedrich P Thinnes
    Mol Genet Metab 97:241-3. 2009
    ..Finally, it is insinuated to search for natural antibodies against type-1 porin, what in combination with other established markers might help in early diagnosis of prostate cancer...
  6. doi request reprint Apoptogenic interactions of plasmalemmal type-1 VDAC and Aβ peptides via GxxxG motifs induce Alzheimer's disease - a basic model of apoptosis?
    Friedrich P Thinnes
    Wien Med Wochenschr 161:274-6. 2011
    ..Considering the ubiquitous expression modus of APP, beta- and gamma-secretases and type-1 VDAC/eukaryotic porin a basic model of apoptosis might be given...