S Thanos

Summary

Country: Germany

Publications

  1. pmc Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy
    Verena Prokosch
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Albert Schweitzer Campus 1, Munster, Germany
    PLoS ONE 8:e49730. 2013
  2. pmc Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat model
    Maurice Schallenberg
    Institute of Experimental Ophthalmology, School of Medicine, University Clinics Münster and Interdisciplinary Centre for Clinical Research IZKF, Munster, Germany
    PLoS ONE 7:e33593. 2012
  3. doi request reprint Clinical transplantation of individualized recipient serum-adapted cornea reduces the risk of graft rejection after keratoplasty
    Solon Thanos
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Munster, Germany
    Cell Transplant 22:477-91. 2013
  4. doi request reprint Traumatology of the optic nerve and contribution of crystallins to axonal regeneration
    Solon Thanos
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Albert Schweitzer Campus 1, D15, 48149 Munster, Germany
    Cell Tissue Res 349:49-69. 2012
  5. ncbi request reprint In vivo FM: using conventional fluorescence microscopy to monitor retinal neuronal death in vivo
    Solon Thanos
    Dept of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Trends Neurosci 25:441-4. 2002
  6. ncbi request reprint Correlation between retinal ganglion cell death and chronically developing inherited glaucoma in a new rat mutant
    Solon Thanos
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Exp Eye Res 79:119-29. 2004
  7. ncbi request reprint Implantable visual prostheses
    S Thanos
    Department of Experimental Ophthalmology, University Eye Hospital and Interdisciplinary Centre of Clinical Research IZKF, Munster, Germany
    Acta Neurochir Suppl 97:465-72. 2007
  8. ncbi request reprint Potential role of Pax-2 in retinal axon navigation through the chick optic nerve stalk and optic chiasm
    Solon Thanos
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, School of Medicine, Domagkstrasse 15, 48149 Munster, Germany
    J Neurobiol 59:8-23. 2004
  9. ncbi request reprint Development of the visual system of the chick. II. Mechanisms of axonal guidance
    S Thanos
    Department of Experimental Ophthalmology, School of Medicine, University of Munster, Domagkstr 15, 48149, Munster, Germany
    Brain Res Brain Res Rev 35:205-45. 2001
  10. ncbi request reprint Glioanatomy assessed by cell-cell interactions and phagocytotic labelling
    S Thanos
    Department of Experimental Ophthalmology, Medical School, University of Muenster, Domagkstrasse 15, D 48149, Muenster, Germany
    J Neurosci Methods 103:39-50. 2000

Collaborators

Detail Information

Publications64

  1. pmc Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy
    Verena Prokosch
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Albert Schweitzer Campus 1, Munster, Germany
    PLoS ONE 8:e49730. 2013
    ..Neuronal crystallins are thus suitable biomarkers for monitoring the progression of neuropathy and evaluating any neuroprotective effects...
  2. pmc Regulation of retinal proteome by topical antiglaucomatous eye drops in an inherited glaucoma rat model
    Maurice Schallenberg
    Institute of Experimental Ophthalmology, School of Medicine, University Clinics Münster and Interdisciplinary Centre for Clinical Research IZKF, Munster, Germany
    PLoS ONE 7:e33593. 2012
    ..The data may facilitate development of eye drops that exert neuroprotection through direct pharmacological effect...
  3. doi request reprint Clinical transplantation of individualized recipient serum-adapted cornea reduces the risk of graft rejection after keratoplasty
    Solon Thanos
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Munster, Germany
    Cell Transplant 22:477-91. 2013
    ..This new donor tissue treatment procedure offers incontrovertible advantages and could be adapted for low-risk eyes as well as other transplantable tissues...
  4. doi request reprint Traumatology of the optic nerve and contribution of crystallins to axonal regeneration
    Solon Thanos
    Institute of Experimental Ophthalmology, School of Medicine, University of Munster, Albert Schweitzer Campus 1, D15, 48149 Munster, Germany
    Cell Tissue Res 349:49-69. 2012
    ..Thus, the post-injury fate of neurons cannot be seen merely as inevitable but, instead, must be regarded as a challenge to shape conditions for initiating growth cone formation to repair the damaged optic nerve...
  5. ncbi request reprint In vivo FM: using conventional fluorescence microscopy to monitor retinal neuronal death in vivo
    Solon Thanos
    Dept of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Trends Neurosci 25:441-4. 2002
    ..The method is a relatively new concept and has potential for the monitoring of retinal conditions, such as glaucoma or optic nerve transection, and for evaluation of neuroprotective strategies in the near future...
  6. ncbi request reprint Correlation between retinal ganglion cell death and chronically developing inherited glaucoma in a new rat mutant
    Solon Thanos
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Exp Eye Res 79:119-29. 2004
    ..This model may help to address several fundamental issues in the pathogenesis of glaucoma and aid in the development of neuroprotective strategies...
  7. ncbi request reprint Implantable visual prostheses
    S Thanos
    Department of Experimental Ophthalmology, University Eye Hospital and Interdisciplinary Centre of Clinical Research IZKF, Munster, Germany
    Acta Neurochir Suppl 97:465-72. 2007
    ..The review ends by pointing to future perspectives in the rapidly accelerating process of visual prosthetics and in the increasing hope that restoration of the visual system becomes reality...
  8. ncbi request reprint Potential role of Pax-2 in retinal axon navigation through the chick optic nerve stalk and optic chiasm
    Solon Thanos
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, School of Medicine, Domagkstrasse 15, 48149 Munster, Germany
    J Neurobiol 59:8-23. 2004
    ..These data suggest that balanced expression of Pax-2 results in the correct formation of the chick chiasm at early stages by imposing accurate pathfinding within the optic stalk and the midline...
  9. ncbi request reprint Development of the visual system of the chick. II. Mechanisms of axonal guidance
    S Thanos
    Department of Experimental Ophthalmology, School of Medicine, University of Munster, Domagkstr 15, 48149, Munster, Germany
    Brain Res Brain Res Rev 35:205-45. 2001
    ....
  10. ncbi request reprint Glioanatomy assessed by cell-cell interactions and phagocytotic labelling
    S Thanos
    Department of Experimental Ophthalmology, Medical School, University of Muenster, Domagkstrasse 15, D 48149, Muenster, Germany
    J Neurosci Methods 103:39-50. 2000
    ..In short, some glial-glial and neuroglial negotiations will be analysed in near future by developing new, or by modifying existing fluorescent probes...
  11. ncbi request reprint Neurobiology of the regenerating retina and its functional reconnection with the brain by means of peripheral nerve transplants in adult rats
    S Thanos
    Department of Experimental Ophthalmology, School of Medicine, University of Munster, Germany
    Surv Ophthalmol 42:S5-26. 1997
    ..Thus, animals could discriminate between simplified vertical versus horizontal stripes, and visual evoked potentials were positive after grafting. (ABSTRACT TRUNCATED)..
  12. ncbi request reprint Exposure to a solar eclipse causes neuronal death in the retina
    S Thanos
    Department of Experimental Ophthalmology, School of Medicine, University of Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 239:794-800. 2001
    ..We used an animal model to monitor the mechanisms of retinal damage following excessive light exposure, and in particular to study whether observation of the eclipse induces death of retinal cells...
  13. ncbi request reprint Restoration of the retinofugal pathway
    P Heiduschka
    Department of Experimental Ophthalmology, , Domagkstrasse 15, , Germany
    Prog Retin Eye Res 19:577-606. 2000
    ..Final elucidation of this delicate system will essentially lead to some revision of our knowledge concerning neurotraumatology and CNS-repair...
  14. ncbi request reprint Aurintricarboxylic acid promotes survival and regeneration of axotomised retinal ganglion cells in vivo
    P Heiduschka
    Department of Experimental Ophthalmology, University of Munster, Domagkstrasse 15, D 48149, Munster, Germany
    Neuropharmacology 39:889-902. 2000
    ..This number could be increased by a second injection of ATA 7 days after axotomy. These data show that ATA is not only able to delay post-traumatic neuronal death but also enhances the extent of axonal regeneration in vivo...
  15. ncbi request reprint Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats
    D Fischer
    Department of Experimental Ophthalmology, School of Medicine, , Domagkstrasse 15, , D-48149, Germany
    Exp Neurol 172:257-72. 2001
    ....
  16. ncbi request reprint Perforated microelectrode arrays implanted in the regenerating adult central nervous system
    P Heiduschka
    Department of Experimental Ophthalmology, , Domagkstrasse 15, , D-48149, Germany
    Exp Neurol 171:1-10. 2001
    ..This study reports for the first time that the optic nerve has unique properties, which aids in the realization of these goals...
  17. ncbi request reprint Retinal ganglion cells resistant to advanced glaucoma: a postmortem study of human retinas with the carbocyanine dye DiI
    Mitrofanis Pavlidis
    Department of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Invest Ophthalmol Vis Sci 44:5196-205. 2003
    ..Perikaryal, axonal, and dendritic alterations were monitored in glaucoma-resistant retinal ganglion cells by postvitam application of the fluorescent dye DiI...
  18. ncbi request reprint Specific transcellular staining of microglia in the adult rat after traumatic degeneration of carbocyanine-filled retinal ganglion cells
    S Thanos
    Department of Ophthalmology, University of Tubingen, School of Medicine, Germany
    Exp Eye Res 55:101-17. 1992
    ..The findings suggest that microglial cells play an important role in axotomy-induced wound healing and removal of cell debris...
  19. ncbi request reprint Cortisol promotes survival and regeneration of axotomised retinal ganglion cells and enhances effects of aurintricarboxylic acid
    Peter Heiduschka
    Department of Experimental Ophthalmology, University of Münster Eye Hospital, Domagkstrasse 15, 48149 Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 244:1512-21. 2006
    ..Due to the anti-inflammatory and microglia-inhibiting properties of glucocorticoids, we studied the neuroprotective effects of intravitreally administered cortisol after an optic nerve cut...
  20. ncbi request reprint Regeneration of retinal ganglion cell axons in organ culture is increased in rats with hereditary buphthalmos
    Julia Lasseck
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Muenster, Domagkstrasse 15, 48149 Muenster, Germany
    Exp Eye Res 85:90-104. 2007
    ..This model may help to elucidate the fundamental mechanisms of optic neuropathy at stages preceding death caused by chronic injury, and aid in the development of neuroprotective strategies...
  21. ncbi request reprint Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma
    Rita Naskar
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Munster, Germany
    Invest Ophthalmol Vis Sci 43:2962-8. 2002
    ..To characterize the early reaction of retinal ganglion cells (RGCs) in a rat model of glaucoma using in vivo imaging and to examine the involvement of retinal microglia in glaucomatous neuropathy...
  22. ncbi request reprint Regeneration of ganglion cell axons into a peripheral nerve graft alters retinal expression of glial markers and decreases vulnerability to re-axotomy
    Erik Schuetz
    Department of Experimental Ophthalmology, University Eye Hospital Munster, School of Medicine, Domagkstr 15, 48149 Munster, Germany
    Restor Neurol Neurosci 21:11-8. 2003
    ....
  23. ncbi request reprint Pathological changes in human retinal ganglion cells associated with diabetic and hypertensive retinopathy
    Birthe Meyer-Rüsenberg
    Department of Experimental Ophthalmology, School of Medicine, University of Munster, Domagkstrasse 15, 48149 Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 245:1009-18. 2007
    ..To examine whether systemic diseases like diabetes and arterial hypertension, which frequently cause retinopathies leading to blindness effect the morphology of retinal ganglion cells (RGC)...
  24. doi request reprint Cholinergic inhibition by botulinum toxin in a rat model of congenital glaucoma raises intraocular pressure
    Z Gatzioufas
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Muenster, Muenster, Germany
    Br J Ophthalmol 92:826-31. 2008
    ..Muscarinic agonists in the trabecular meshwork tissue increase aqueous humour outflow facility by a direct stimulation of ciliary muscle contraction. We investigated the contribution of cholinergic state to IOP regulation...
  25. doi request reprint [Concomitant cellular reactions in optic nerve siderosis existing for 30 years]
    V Prokosch
    Institut für Experimentelle Ophthalmologie, Westfalische Wilhelms Universitat Munster, Domagkstr 15, 48149, Munster, Deutschland
    Ophthalmologe 108:372-7. 2011
    ..These findings hold out hope and may serve as the starting point for regenerative medicine to potentially restore neuronal function...
  26. ncbi request reprint Positional determination of the naso-temporal retinal axis coincides with asymmetric expression of proteins along the anterior-posterior axis of the eye primordium
    S Thanos
    Department of Ophthalmology, University of Tubingen, School of Medicine, Germany
    Exp Eye Res 63:479-92. 1996
    ..The difference in the protein expression may explain that mixing the positionally specified cells of either origins results in projection mosaics...
  27. ncbi request reprint Can lenticular factors improve the posttrauma fate of neurons?
    T Stupp
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital of Münster and Interdisciplinary Clinical Research Center IZKF, Domagkstrasse 15, D 48149 Munster, Germany
    Prog Retin Eye Res 24:241-57. 2005
    ..It is concluded that survival factors supplied by the lens might be used to facilitate survival within neuronal tissue...
  28. ncbi request reprint AMOG/beta2 and glioma invasion: does loss of AMOG make tumour cells run amok?
    V Senner
    Institute of Neuropathology, University Hospital, Munster, Germany
    Neuropathol Appl Neurobiol 29:370-7. 2003
    ..We conclude that increasing loss of AMOG/beta2 during malignant progression parallels and may underlie the extensive invasion pattern of malignant gliomas...
  29. doi request reprint [Factors influencing the long-term success of lacrimal duct surgery and the prognostic value of dacryocystography]
    T Stupp
    Universitatsaugenklinik, Universitat Munster
    Klin Monbl Augenheilkd 227:43-6. 2010
    ....
  30. ncbi request reprint Systemic adverse events: a comparison between topical and peribulbar anaesthesia in cataract surgery
    Tobias Stupp
    University Eye Hospital, Munster, Germany
    Ophthalmologica 221:320-5. 2007
    ..To evaluate the safety of topical anaesthesia (TA) versus peribulbar anaesthesia (PBA) in patients undergoing routine cataract surgery on the basis of systemic adverse events...
  31. ncbi request reprint Ultrasonic visualization of the effect of blinking on the lacrimal pump mechanism
    Mitrofanis Pavlidis
    University Eye Hospital Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 243:228-34. 2005
    ..The role of the lacrimal sac (LS) and the medial canthal tendon in the lacrimal pump mechanism is controversial. This study used ultrasonic visualization to analyze this phenomenon...
  32. ncbi request reprint Morphometric examination of human and monkey retinal ganglion cells within the papillomacular area
    Mitrofanis Pavlidis
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse 15, D 48149 Munster, Germany
    Retina 26:445-53. 2006
    ..To examine the morphology of the retinal ganglion cells (RGCs) in the lesser characterized area lying between the optic disk and the macula that consists of the central papillomacular area (PMA) and the arcuate papillomacular bundle (PMB)...
  33. ncbi request reprint Multifocal electroretinography changes in the macula at high altitude: a report of three cases
    Mitrofanis Pavlidis
    University Eye Hospital Munster, Germany
    Ophthalmologica 219:404-12. 2005
    ....
  34. ncbi request reprint Intraocular pressure changes during high-altitude acclimatization
    Mitrofanis Pavlidis
    Department of Experimental Ophthalmology, University Eye Hospital of Münster, Domagkstrasse 15, 48149, Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 244:298-304. 2006
    ..To evaluate the relationship between hypobaric hypoxia acclimatization and intraocular pressure (IOP) during ascent, acclimatization, and descent between 2286 m and 5050 m...
  35. ncbi request reprint Sodium dodecyl sulfate versus acid-labile surfactant gel electrophoresis: comparative proteomic studies on rat retina and mouse brain
    Simone König
    Integrated Functional Genomics, Interdisciplinary Clinical Research Center, University of Eye Hospital Münster, University of Munster, Munster, Germany
    Electrophoresis 24:751-6. 2003
    ..The promising results of the use of ALS in bioanalytics call for detailed physicochemical investigations of surfactant properties...
  36. ncbi request reprint Presurgical and postsurgical ultrasound assessment of lacrimal drainage dysfunction
    Tobias Stupp
    University Eye Hospital Munster, Munster, Germany
    Am J Ophthalmol 138:764-71. 2004
    ..The purpose of this study was to examine the usability and reliability of ultrasonography in the evaluation of the lacrimal drainage system...
  37. ncbi request reprint Lens epithelium supports axonal regeneration of retinal ganglion cells in a coculture model in vitro
    Tobias Stupp
    Department of Experimental Ophthalmology, Interdisciplinary Research Centre IZKF, School of Medicine, University Eye Hospital Munster, Domagkstr 15, 48149 Munster, Germany
    Exp Eye Res 81:530-8. 2005
    ..These findings indicate that the lens epithelium influences both the amount of axonal regeneration and the direction of growth without affecting the survival rate of retinal ganglion cells in vitro...
  38. ncbi request reprint Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure
    Rita Naskar
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Muenster, Muenster, Germany
    Mol Vis 12:1199-210. 2006
    ..To characterize the changes in retinal gene expression induced by elevated intraocular pressure (IOP) in a hereditary rodent model...
  39. ncbi request reprint Translin-associated factor-X (Trax) is a molecular switch of growth-associated protein (GAP)-43 that controls axonal regeneration
    Uwe Schröer
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse 15, 48149 Munster, Germany
    Eur J Neurosci 26:2169-78. 2007
    ..These data suggest that Trax regulates GAP-43 transcription and regeneration-promoting effects during the postnatal maturation period. Trax may represent a new potent therapeutic target gene for optic nerve and spinal cord injuries...
  40. doi request reprint A coculture assay to visualize and monitor interactions between migrating glioma cells and nerve fibers
    Patrick Oellers
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse, Munster, Germany
    Nat Protoc 4:923-7. 2009
    ....
  41. ncbi request reprint Neuro-glial interactions in the adult rat retina after reaxotomy of ganglion cells: examination of neuron survival and phagocytic microglia using fluorescent tracers
    Erik Schuetz
    Department of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstrasse 15, 48149 Munster, Germany
    Brain Res Bull 62:391-6. 2004
    ..The microglial capability to phagocytose dying neurons several fold emphasizes their function in permanent scavenging within the retina...
  42. doi request reprint ROCKs are expressed in brain tumors and are required for glioma-cell migration on myelinated axons
    Patrick Oellers
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Domagkstrasse 15, Munster, Germany
    Glia 57:499-509. 2009
    ..These data suggest that the mechanisms underlying the migration of glioma cells on myelinated axons differ from those underlying the migration on extracellular matrix molecules such as laminin-1...
  43. ncbi request reprint Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2)
    Thomas Liedtke
    Department of Experimental Ophthalmology, University of Munster, Germany
    Mol Cell Proteomics 6:895-907. 2007
    ..The results suggest that neuronal crystallins constitute a novel class of neurite-promoting factors that likely operate through an autocrine mechanism and that they could be used in neurodegenerative diseases...
  44. ncbi request reprint Axonal regeneration in the organotypically cultured monkey retina: biological aspects, dependence on substrates and age-related proteomic profiling
    Karin Rose
    Department of Experimental Ophthalmology, University Eye Hospital Munster, Munster, Germany
    Restor Neurol Neurosci 26:249-66. 2008
    ..To our knowledge these data are the first from subhuman animals to suggest that axonal regeneration of injured RGCs is correlated to expression of identifiable proteins within the retina...
  45. doi request reprint Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve
    Petar Charalambous
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Munster, Munster, Germany
    Invest Ophthalmol Vis Sci 49:3513-24. 2008
    ....
  46. ncbi request reprint [Sudden transient bilateral loss of sight]
    V Prokosch
    Universitätsaugenklinik Münster, Domagkstrasse 15, 48149 Munster, Deutschland
    Ophthalmologe 105:278-80. 2008
  47. doi request reprint Everolimus improves experimental autoimmune uveoretinitis
    M Hennig
    Ophtha Lab, Department of Ophthalmology, St Franziskus Hospital, Muenster, Germany
    Exp Eye Res 105:43-52. 2012
    ..These results indicate that the immunosuppressive effect of everolimus on EAU was associated with the suppression of pathogenic effector responses and induction of regulatory T cells...
  48. ncbi request reprint Acute keratoconus induced by hypothyroxinemia during pregnancy
    Z Gatzioufas
    Department of Experimental Ophthalmology, University Eye Hospital Muenster, Muenster, Germany
    J Endocrinol Invest 31:262-6. 2008
    ..This case report is the first to suggest that changes in maternal thyroid hormone levels during pregnancy can aggravate the progression of keratoconus...
  49. ncbi request reprint Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNA-deleted mice
    L Lewejohann
    Department of Behavioural Biology, University of Munster, D 48149 Munster, Germany
    Behav Brain Res 154:273-89. 2004
    ..In the outdoor pen, the survival rates of BC1-depleted mice were lower than in controls. Thus, we conclude that the neuron-specific non-messenger BC1 RNA contributes to the aptive modulation of behaviour...
  50. ncbi request reprint Transformation of adult retina from the regenerative to the axonogenesis state activates specific genes in various subsets of neurons and glial cells
    Thomas Liedtke
    Department of Experimental Ophthalmology, University Eye Hospital Münster Domagkstrasse, Muenster, Germany
    Glia 55:189-201. 2007
    ....
  51. ncbi request reprint Measurement of nitric oxide production by the lesioned rat retina with a sensitive nitric oxide electrode
    Markus Groppe
    Department of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstr 15, 48149, Munster, Germany
    Anal Bioanal Chem 376:797-807. 2003
    ..NO concentration is elevated after an axotomy reaching its highest value of up to 30 microM 5 days after the lesion. The NO concentration is decreased below the initial value after 9-14 days post axotomy...
  52. doi request reprint GM-CSF regulates the ERK1/2 pathways and protects injured retinal ganglion cells from induced death
    Maurice Schallenberg
    Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Münster and Interdisciplinary Centre for Clinical Research IZKF, Domagkstrasse 15, D 48149 Munster, Germany
    Exp Eye Res 89:665-77. 2009
    ..Like in vitro, GM-CSF counteracts the staurosporine-induced cell death in vivo and protects RGCs from axotomy-induced degeneration. Our data suggest that GM-CSF might be a novel therapeutic agent in neuropathic disease of the eye...
  53. ncbi request reprint Isolation of total-RNA from formalin-fixed rat retina
    S Stoll
    Department of Experimental Ophthalmology, University of Münster Eye Hospital, Domagkstrasse 15, 48149, Munster, Germany
    J Neurosci Methods 120:55-63. 2002
    ..This approach shows that tissue fixation prior to RNA-isolation facilitates the rapid isolation of undamaged RNAs in tissues such as the retina, which are known to yield low levels of RNA and are vulnerable to RNases...
  54. ncbi request reprint Growth-associated protein-43 expression in the lens of rats and primates
    Tobias Stupp
    Department of Experimental Ophthalmology, University Eye Hospital, Munster, Germany
    Neuroreport 18:7-11. 2007
    ..These results suggest that growth-associated protein-43 is involved in differentiation processes also outside the nervous system...
  55. ncbi request reprint Treatment of basal cell carcinoma of the eyelids with 5% topical imiquimod: a 3-year follow-up study
    Raveewan Choontanom
    University Eye Hospital, Domagkstr 15, 48149 Munster, Germany
    Graefes Arch Clin Exp Ophthalmol 245:1217-20. 2007
    ..The aim of this study was to determine the efficacy and safety of 5% topical imiquimod, and the long-term results following its use, in the treatment of nodular basal cell carcinoma (BCC) of the eyelid...
  56. ncbi request reprint Recovery of visual evoked potentials after regeneration of cut retinal ganglion cell axons within the ascending visual pathway in adult rats
    Peter Heiduschka
    Department of Experimental Ophthalmology, University Eye Hospital Munster, Domagkstr 15, D 48149 Munster, Germany
    Restor Neurol Neurosci 23:303-12. 2005
    ..In this study, we check time-dependence and extent of restoration of flash visual evoked potentials (FVEPs) to examine the functional relevance of the regenerated retinogeniculate pathway...
  57. ncbi request reprint Reciprocal transmission of herpes simplex virus type 1 (HSV-1) between corneal epithelium and trigeminal neurites in an embryonic chick organ culture
    Wali Hafezi
    Institut fur Medizinische Mikrobiologie, Abteilung Klinische Virologie, Universitat Munster, Munster, Germany
    FASEB J 16:878-80. 2002
    ....
  58. ncbi request reprint Distribution of scotoma pattern related to chiasmal lesions with special reference to anterior junction syndrome
    Ulrich Schiefer
    Department of Pathophysiology of Vision and Neuro ophthalmology, University Eye Hospital, Schleichstrasse 12 16, 72076 Tubingen, Germany
    Graefes Arch Clin Exp Ophthalmol 242:468-77. 2004
    ..Secondly, to reconsider the existence of "Wilbrand's knee" as far as referable to the anterior junction syndrome...
  59. ncbi request reprint UV irradiation causes multiple cellular changes in cultured human retinal pigment epithelium cells
    Karla S Tratsk
    University Hospital, University Federal of Santa Catarina, Campus Universitario, 88040 970 Florianópolis SC, Brazil
    Graefes Arch Clin Exp Ophthalmol 241:852-9. 2003
    ..The purpose of this study was to examine cellular changes in the retinal pigment epithelium induced by direct irradiation with UV light in culture...
  60. ncbi request reprint Benzodiazepine and kainate receptor binding sites in the RCS rat retina
    Kalliopi Stasi
    Department of Physiology, Faculty of Medicine, University of Patras, 26500, Patras, Greece
    Graefes Arch Clin Exp Ophthalmol 241:154-60. 2003
    ....
  61. ncbi request reprint Neuronal MAP2 mRNA: species-dependent differential dendritic targeting competence
    Massimiliano Cristofanilli
    Department of Physiology and Pharmacology, State University of New York, Health Science Center at Brooklyn, 11203, USA
    J Mol Biol 341:927-34. 2004
    ..The data thus suggest that the acquisition of such competence has likely been a relatively recent event in evolution...
  62. ncbi request reprint Ink-jet printing for micropattern generation of laminin for neuronal adhesion
    Florin Turcu
    Anal Chem Elektroanalytik and Sensorik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    J Neurosci Methods 131:141-8. 2003
    ..These findings open the route for the generation of complex small neuronal arrays and for the electrochemical investigation of the obtained neuronal matrix...
  63. ncbi request reprint Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation
    Dietmar Fischer
    Laboratories for Neuroscience Research in Neurosurgery, Children s Hospital, Boston, Massachusetts 02115, USA
    J Neurosci 24:8726-40. 2004
    ....
  64. ncbi request reprint The 'free-floating' retina epoch: new models for new scopes
    Solon Thanos
    Ophthalmic Res 38:261-2. 2006