M Tepel

Summary

Country: Germany

Publications

  1. ncbi request reprint Regulation of the Na+/H+ antiporter in patients with mild chronic renal failure: effect of glucose
    M Tepel
    Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    Kidney Int 56:172-80. 1999
  2. ncbi request reprint Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    N Engl J Med 343:180-4. 2000
  3. ncbi request reprint Increased intracellular reactive oxygen species in patients with end-stage renal failure: effect of hemodialysis
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    Kidney Int 58:867-72. 2000
  4. ncbi request reprint Increased sodium-proton antiporter activity in patients with obstructive sleep apnoea
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Germany
    J Sleep Res 9:285-91. 2000
  5. ncbi request reprint Efficacy and tolerability of angiotensin II type 1 receptor antagonists in dialysis patients using AN69 dialysis membranes
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Deutschland
    Kidney Blood Press Res 24:71-4. 2001
  6. ncbi request reprint Activation of Na+, H+ exchanger produces vasoconstriction of renal resistance vessels
    M Tepel
    , Medizinische Klinik I, , Herne, Germany
    Am J Hypertens 11:1214-21. 1998
  7. pmc Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney
    M van der Giet
    Ruhr Universitat Bochum, Marienhospital Herne, Med Klinik I, Germany
    Br J Pharmacol 127:1463-9. 1999
  8. ncbi request reprint Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates
    J Jankowski
    Medizinische Klinik I, , , Herne, Germany
    Kidney Int 59:1134-41. 2001
  9. ncbi request reprint Diadenosine polyphosphates' action on calcium and vessel contraction
    M Tepel
    , Medizinische Klinik I, , Herne, Germany
    Am J Hypertens 10:1404-10. 1997
  10. ncbi request reprint Characterization of p-hydroxy-hippuric acid as an inhibitor of Ca2+-ATPase in end-stage renal failure
    J Jankowski
    Medizinische Klinik I, , , Herne, Germany
    Kidney Int Suppl 78:S84-8. 2001

Detail Information

Publications14

  1. ncbi request reprint Regulation of the Na+/H+ antiporter in patients with mild chronic renal failure: effect of glucose
    M Tepel
    Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    Kidney Int 56:172-80. 1999
    ..The aim of this study was to determine the glucose-dependent regulation of the sodium-proton-antiporter (Na+/H+ antiporter) in patients with mild chronic renal failure (CRF)...
  2. ncbi request reprint Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    N Engl J Med 343:180-4. 2000
    ..Radiographic contrast agents can cause a reduction in renal function that may be due to reactive oxygen species. Whether the reduction can be prevented by the administration of antioxidants is unknown...
  3. ncbi request reprint Increased intracellular reactive oxygen species in patients with end-stage renal failure: effect of hemodialysis
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Herne, Germany
    Kidney Int 58:867-72. 2000
    ..Reactive oxygen species (ROS) have been implicated in various forms of cellular injury. ROS may cause cell damage and are involved in the pathophysiology of several diseases, including atherosclerosis and chronic inflammation...
  4. ncbi request reprint Increased sodium-proton antiporter activity in patients with obstructive sleep apnoea
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Germany
    J Sleep Res 9:285-91. 2000
    ..00 and 13.26 +/- 6.13 x 10(-3) pH(i)/s at 02.00. From the present results it is concluded that an increased cellular Na(+)/H(+) antiporter activity may be a genetic marker for patients who are predisposed to obstructive sleep apnoea...
  5. ncbi request reprint Efficacy and tolerability of angiotensin II type 1 receptor antagonists in dialysis patients using AN69 dialysis membranes
    M Tepel
    Medizinische Klinik I, Universitatsklinik Marienhospital, Ruhr Universitat Bochum, Deutschland
    Kidney Blood Press Res 24:71-4. 2001
    ..The patients (6 male, 5 female; mean age +/- SD 61+/-11 years) were on regular bicarbonate hemodialysis three times weekly for more than 3 months using acrylonitrile and sodium methallyl sulfonate copolymer (AN69) dialysis membranes...
  6. ncbi request reprint Activation of Na+, H+ exchanger produces vasoconstriction of renal resistance vessels
    M Tepel
    , Medizinische Klinik I, , Herne, Germany
    Am J Hypertens 11:1214-21. 1998
    ....
  7. pmc Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney
    M van der Giet
    Ruhr Universitat Bochum, Marienhospital Herne, Med Klinik I, Germany
    Br J Pharmacol 127:1463-9. 1999
    ....
  8. ncbi request reprint Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates
    J Jankowski
    Medizinische Klinik I, , , Herne, Germany
    Kidney Int 59:1134-41. 2001
    ..10 +/- 1; Ap(6)A, 141 +/- 45 vs. 4 +/- 1; each P < 0.01]. CONCLUSIONS: The increased amount of dinucleoside polyphosphate in platelets from hemodialysis patients may be an important additional atherogenic factor...
  9. ncbi request reprint Diadenosine polyphosphates' action on calcium and vessel contraction
    M Tepel
    , Medizinische Klinik I, , Herne, Germany
    Am J Hypertens 10:1404-10. 1997
    ..It is concluded that diadenosine polyphosphates increase [Ca2+]i and hence cause vessel constriction...
  10. ncbi request reprint Characterization of p-hydroxy-hippuric acid as an inhibitor of Ca2+-ATPase in end-stage renal failure
    J Jankowski
    Medizinische Klinik I, , , Herne, Germany
    Kidney Int Suppl 78:S84-8. 2001
    ..The EC50 (log mol/L; mean +/- SEM) for p-hydroxy-hippuric acid was calculated as 4.82 +/- 0.14. In conclusion, p-hydroxy-hippuric acid may play a role in disturbed Ca2+ metabolism in end-stage renal failure...
  11. ncbi request reprint CoenzymeA glutathione disulfide is a potent modulator of angiotensin II-induced vasoconstriction
    M van der Giet
    , , Medizinische Klinik I, Herne, Germany
    Am J Hypertens 14:164-8. 2001
    ..We conclude that CoASSG is able to potentiate the vasoactive properties of AngII, and that CoASSG might play an important role in BP regulation via modulating effects of AngII...
  12. ncbi request reprint Influence of treatment on leptin levels in patients with obstructive sleep apnoea
    B M Sanner
    Dept of Medicine I, Ruhr University Bochum, Marienhospital Herne, Bochum, Germany
    Eur Respir J 23:601-4. 2004
    ..Changes in leptin levels are related to changes in apnoea/hypopnoea index in obstructive sleep apnoea syndrome patients...
  13. ncbi request reprint [Medical treatment of hypertension--what treatment for what patients?]
    W Zidek
    Medizinischen Klinik IV Charité, Universitatsmedizin Berlin
    MMW Fortschr Med 146:31-4. 2004
    ..Resistance to therapy should prompt consideration of a number of causes, in particular noncompliance on the part of the patient...
  14. ncbi request reprint [Role of transient receptor potential channels in the cardiovascular system]
    M Tepel
    Medizinische Klinik Nephrologie, Charite Campus Benjamin Franklin, Berlin
    Dtsch Med Wochenschr 132:2442-4. 2007