Hans Ulrich Wittchen

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. ncbi request reprint [Anxiety disorders in DSM-5: an overview on changes in structure and content]
    H U Wittchen
    Institut für Klinische Psychologie und Psychotherapie and Center of Clinical Epidemiology and Longitudinal Studies, Technische Universitat Dresden, Chemnitzer Str 46, 01187, Dresden, Deutschland
    Nervenarzt 85:548-52. 2014
  2. pmc The MentDis_ICF65+ study protocol: prevalence, 1-year incidence and symptom severity of mental disorders in the elderly and their relationship to impairment, functioning (ICF) and service utilisation
    Sylke Andreas
    Department of Medical Psychology, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Martinistr, 52, Building W 26, Hamburg D 20246, Germany
    BMC Psychiatry 13:62. 2013
  3. pmc Traumatic experiences and posttraumatic stress disorder in soldiers following deployment abroad: how big is the hidden problem?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies, Technische Universitat Dresden, Dresden, Germany
    Dtsch Arztebl Int 109:559-68. 2012
  4. ncbi request reprint [Generalized anxiety disorder in primary care. Patterns of healthcare utilization in Germany]
    H U Wittchen
    Technische Universitat Dresden, Deutschland
    MMW Fortschr Med 154:77-84. 2012
  5. doi request reprint Omalizumab versus 'usual care': results from a naturalistic longitudinal study in routine care
    H U Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Int Arch Allergy Immunol 159:83-93. 2012
  6. doi request reprint Prevalence, incidence and determinants of PTSD and other mental disorders: design and methods of the PID-PTSD+3 study
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Int J Methods Psychiatr Res 21:98-116. 2012
  7. pmc Social Phobia in an Italian region: do Italian studies show lower frequencies than community surveys conducted in other European countries?
    Mauro Giovanni Carta
    Division of Psychiatry, Department of Public Health, University of Cagliari, Italy
    BMC Psychiatry 4:31. 2004
  8. doi request reprint Women-specific mental disorders in DSM-V: are we failing again?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    Arch Womens Ment Health 13:51-5. 2010
  9. ncbi request reprint Depressive episodes--evidence for a causal role of primary anxiety disorders?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Dresden University of Technology, Chemnitzerstrasse 46, 01187 Dresden, Germany
    Eur Psychiatry 18:384-93. 2003
  10. ncbi request reprint Cannabis use and cannabis use disorders and their relationship to mental disorders: a 10-year prospective-longitudinal community study in adolescents
    Hans Ulrich Wittchen
    Clinical Psychology and Psychotherapy, Technical University Dresden, D 01187 Dresden, Germany
    Drug Alcohol Depend 88:S60-70. 2007

Detail Information

Publications130 found, 100 shown here

  1. ncbi request reprint [Anxiety disorders in DSM-5: an overview on changes in structure and content]
    H U Wittchen
    Institut für Klinische Psychologie und Psychotherapie and Center of Clinical Epidemiology and Longitudinal Studies, Technische Universitat Dresden, Chemnitzer Str 46, 01187, Dresden, Deutschland
    Nervenarzt 85:548-52. 2014
    ..Furthermore, diagnosis-specific and cross-cutting dimensional anxiety scales have been developed to supplement categorical diagnosis which appears to facilitate assessment of severity and course of treatment...
  2. pmc The MentDis_ICF65+ study protocol: prevalence, 1-year incidence and symptom severity of mental disorders in the elderly and their relationship to impairment, functioning (ICF) and service utilisation
    Sylke Andreas
    Department of Medical Psychology, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Martinistr, 52, Building W 26, Hamburg D 20246, Germany
    BMC Psychiatry 13:62. 2013
    ..Therefore, the aims of the MentDis_ICF65+ study are (1) to adapt existing assessment instruments, and (2) to collect data on the prevalence, the incidence, and the natural course and prognosis of mental disorders in the elderly...
  3. pmc Traumatic experiences and posttraumatic stress disorder in soldiers following deployment abroad: how big is the hidden problem?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies, Technische Universitat Dresden, Dresden, Germany
    Dtsch Arztebl Int 109:559-68. 2012
    ..Little is known about the frequency of traumatic event exposure and the development of post-traumatic stress disorder (PTSD) among German soldiers serving in Afghanistan...
  4. ncbi request reprint [Generalized anxiety disorder in primary care. Patterns of healthcare utilization in Germany]
    H U Wittchen
    Technische Universitat Dresden, Deutschland
    MMW Fortschr Med 154:77-84. 2012
    ..Generalized Anxiety Disorder (GAD) has been described in community studies as a frequent and costly high utilizer group in the primary care sector. Administrative data supporting this observation are lacking so far...
  5. doi request reprint Omalizumab versus 'usual care': results from a naturalistic longitudinal study in routine care
    H U Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Int Arch Allergy Immunol 159:83-93. 2012
    ..It is unclear how far the superior efficacy of omalizumab, established in randomized controlled clinical trials of patients with severe allergic asthma (SAA), translates into routine practice and when compared to matched controls...
  6. doi request reprint Prevalence, incidence and determinants of PTSD and other mental disorders: design and methods of the PID-PTSD+3 study
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Int J Methods Psychiatr Res 21:98-116. 2012
    ..We expect the findings to advance our understanding of a wide spectrum of adverse mental health outcomes beyond PTSD...
  7. pmc Social Phobia in an Italian region: do Italian studies show lower frequencies than community surveys conducted in other European countries?
    Mauro Giovanni Carta
    Division of Psychiatry, Department of Public Health, University of Cagliari, Italy
    BMC Psychiatry 4:31. 2004
    ..5% to 16.0%. The aim of this study was to assess the frequency of SP in Sardinia (Italy) in order to verify the evidence of a lower frequency of SP in Italy observed in previous studies (from 1.0% to 3.1%)...
  8. doi request reprint Women-specific mental disorders in DSM-V: are we failing again?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    Arch Womens Ment Health 13:51-5. 2010
    ....
  9. ncbi request reprint Depressive episodes--evidence for a causal role of primary anxiety disorders?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Dresden University of Technology, Chemnitzerstrasse 46, 01187 Dresden, Germany
    Eur Psychiatry 18:384-93. 2003
    ..The goal of this paper is to review recent literature, summarize implications of previous findings, and suggest directions for future research regarding preventive and intervention strategies...
  10. ncbi request reprint Cannabis use and cannabis use disorders and their relationship to mental disorders: a 10-year prospective-longitudinal community study in adolescents
    Hans Ulrich Wittchen
    Clinical Psychology and Psychotherapy, Technical University Dresden, D 01187 Dresden, Germany
    Drug Alcohol Depend 88:S60-70. 2007
    ..Whereas the role of externalizing disorders is relatively well established in predicting the onset of cannabis use (CU) or cannabis use disorder (CUD), the status of anxiety and mood disorders in predicting CU and CUD remains controversial...
  11. ncbi request reprint Posttraumatic stress disorder: diagnostic and epidemiological perspectives
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    CNS Spectr 14:5-12. 2009
    ..A further exploitation of the existing data, and an improvement of existing epidemiological methods, strategies, and assessments are likely to substantially contribute to the clarification of unresolved diagnostic issues...
  12. ncbi request reprint Buprenorphine and methadone in the treatment of opioid dependence: methods and design of the COBRA study
    Hans Ulrich Wittchen
    Institut für Klinische Psychologie und Psychotherapie, TU Dresden, Germany
    Int J Methods Psychiatr Res 14:14-28. 2005
    ..The COBRA study provides a unique comprehensive database, informing about the natural allocation and intervention processes in routine care and about the course and outcome of patients treated with buprenorphine or methadone...
  13. ncbi request reprint Cardiovascular risk factors in primary care: methods and baseline prevalence rates--the DETECT program
    H U Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    Curr Med Res Opin 21:619-30. 2005
    ....
  14. doi request reprint Agoraphobia and panic. Prospective-longitudinal relations suggest a rethinking of diagnostic concepts
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Psychother Psychosom 77:147-57. 2008
    ..The aim of the current study is to prospectively examine the 10-year natural course of PA, PD and AG in the first three decades of life, their stability and their reciprocal transitions...
  15. ncbi request reprint Natural course and burden of bipolar disorders
    Hans Ulrich Wittchen
    Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy D 01062 Dresden, Germany
    Int J Neuropsychopharmacol 6:145-54. 2003
    ..iii) The value of both types of studies might be enhanced, if beyond the use of standardized diagnostic interview, special attempts are made to use prospective life- and episode-charting methods for bipolar illnesses...
  16. doi request reprint Developments in the treatment and diagnosis of anxiety disorders
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
    Psychiatr Clin North Am 32:xiii-xix. 2009
    ..This article reviews these critical issues and sets the stage for the other articles in this special issue...
  17. doi request reprint The position of anxiety disorders in structural models of mental disorders
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universita t Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
    Psychiatr Clin North Am 32:465-81. 2009
    ..Extant results are not stable enough to form the basis of clinical diagnostic classification systems such as DSM and the International Classification of Diseases...
  18. doi request reprint The structure of mental disorders re-examined: is it developmentally stable and robust against additions?
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    Int J Methods Psychiatr Res 18:189-203. 2009
    ..However, again, there is little consistency in findings when different age groups or different diagnoses are considered. Our findings suggest that psychopathology cannot be reduced to any simple structure...
  19. doi request reprint Agoraphobia: a review of the diagnostic classificatory position and criteria
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, D 01187Dresden, Germany
    Depress Anxiety 27:113-33. 2010
    ....
  20. doi request reprint Smoking cessation in primary care - a randomized controlled trial of bupropione, nicotine replacements, CBT and a minimal intervention
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Int J Methods Psychiatr Res 20:28-39. 2011
    ..Smoking cessation has been shown to be effective in randomized controlled trials. It is unclear though, whether interventions also work in routine primary care...
  21. doi request reprint The size and burden of mental disorders and other disorders of the brain in Europe 2010
    H U Wittchen
    Institute of Clinical Psychology and Psychotherapy, Center of Epidemiology and Longitudinal Studies CELOS, Technische Universitat Dresden, Dresden, Germany
    Eur Neuropsychopharmacol 21:655-79. 2011
    ....
  22. ncbi request reprint Met and unmet needs in the management of depressive disorder in the community and primary care: the size and breadth of the problem
    H U Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    J Clin Psychiatry 62:23-8. 2001
    ..With this management strategy, access to care can be broadened to include not only the severely ill, but also patients in earlier stages of their depressive illness process who might profit most from modern treatment methods...
  23. doi request reprint Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's disease
    Oliver Riedel
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
    J Neurol 257:1073-82. 2010
    ..PD outpatients are at an increased risk for all neuropsychiatric conditions, increasing with PD severity but not with age or age of onset (except dementia), revealing challenging symptom patterns...
  24. ncbi request reprint Risk factors for premenstrual dysphoric disorder in a community sample of young women: the role of traumatic events and posttraumatic stress disorder
    Axel Perkonigg
    Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    J Clin Psychiatry 65:1314-22. 2004
    ....
  25. doi request reprint The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disorders
    Silke Behrendt
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, D 01187 Dresden, Germany
    Drug Alcohol Depend 123:48-56. 2012
    ..However, the cross-substance relationship between a younger age at onset of alcohol use (AU) and nicotine use (NU) and the risk of cannabis use disorders (CUD) in adolescence and early adulthood remains unclear...
  26. doi request reprint Pain associated with specific anxiety and depressive disorders in a nationally representative population sample
    Katja Beesdo
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187, Dresden, Germany
    Soc Psychiatry Psychiatr Epidemiol 45:89-104. 2010
    ....
  27. doi request reprint The structure of common mental disorders: a replication study in a community sample of adolescents and young adults
    Katja Beesdo-Baum
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    Int J Methods Psychiatr Res 18:204-20. 2009
    ....
  28. ncbi request reprint Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of life
    Katja Beesdo
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Arch Gen Psychiatry 64:903-12. 2007
    ....
  29. ncbi request reprint Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination Survey
    Frank Jacobi
    Institute of Clinical Psychology and Psychotherapy, Unit, Technical University of Dresden, Germany
    Int J Methods Psychiatr Res 11:1-18. 2002
    ..Overall, the GHS core survey and its mental health supplement provide the mental health research community with complex data that allow for high-quality analysis of mental disorders and associations with somatic disorders...
  30. doi request reprint Incidence and risk patterns of anxiety and depressive disorders and categorization of generalized anxiety disorder
    Katja Beesdo
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer St 46, 01187 Dresden, Germany
    Arch Gen Psychiatry 67:47-57. 2010
    ..Controversy surrounds the diagnostic categorization of generalized anxiety disorder (GAD)...
  31. ncbi request reprint What characteristics of primary anxiety disorders predict subsequent major depressive disorder?
    Antje Bittner
    Department of Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany
    J Clin Psychiatry 65:618-26, quiz 730. 2004
    ....
  32. doi request reprint Occurrence risk and structure of depression in Parkinson disease with and without dementia: results from the GEPAD Study
    Oliver Riedel
    Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    J Geriatr Psychiatry Neurol 23:27-34. 2010
    ....
  33. ncbi request reprint Generalized anxiety and depression in primary care: prevalence, recognition, and management
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    J Clin Psychiatry 63:24-34. 2002
    ....
  34. doi request reprint Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patients
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzerstrasse 46, 01187 Dresden, Germany
    Drug Alcohol Depend 95:245-57. 2008
    ..Despite many short-term studies, little is known about the long-term (12-month) effects of these treatments in different settings, i.e. primary care-based (PMC) and specialized substitution centers (SSCs)...
  35. doi request reprint A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life: Evidence for heterogeneity and different treatment needs
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, D 01187 Dresden, Germany
    Drug Alcohol Depend 102:151-7. 2009
    ..Cannabis use (CU) and disorders (CUD) are highly prevalent among adolescents and young adults. We aim to identify clinically meaningful latent classes of users of cannabis and other illegal substances with distinct problem profiles...
  36. doi request reprint Clock drawing test: is it useful for dementia screening in patients having Parkinson disease with and without depression?
    Oliver Riedel
    Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Germany
    J Geriatr Psychiatry Neurol 26:151-7. 2013
    ..Our results indicate that CDT is a suitable screening instrument in patients with PD, but test results from patients with depression warrant careful consideration. ..
  37. doi request reprint Social fear and social phobia types among community youth: differential clinical features and vulnerability factors
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    J Psychiatr Res 45:111-20. 2011
    ....
  38. ncbi request reprint Substance use and substance use disorders in a community sample of adolescents and young adults: incidence, age effects and patterns of use
    Axel Perkonigg
    Department of Clinical Psychology and Psychotherapy, Dresden University of Technology, Dresden, Germany
    Eur Addict Res 12:187-96. 2006
    ..Patterns of onset, cohort trends, and use of various substance classes are also analyzed...
  39. ncbi request reprint [Prevalence, drug treatment and metabolic control of diabetes mellitus in primary care]
    David Pittrow
    Institut fur Klinische Pharmakologie, Forschungsverbund Public Health, Technische Universitat Dresden, Dresden, Germany
    Med Klin (Munich) 101:635-44. 2006
    ....
  40. ncbi request reprint Size and burden of mental disorders in Europe--a critical review and appraisal of 27 studies
    Hans Ulrich Wittchen
    Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
    Eur Neuropsychopharmacol 15:357-76. 2005
    ..These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations...
  41. doi request reprint Psychometric properties of the dimensional anxiety scales for DSM-V in an unselected sample of German treatment seeking patients
    Katja Beesdo-Baum
    Institute of Clinical Psychology and Psychotherapy, Tech nische Universitaet Dresden, Germany
    Depress Anxiety 29:1014-24. 2012
    ..These scales use a common template to assess core constructs of fear and anxiety...
  42. doi request reprint The diagnostic threshold of generalized anxiety disorder in the community: a developmental perspective
    Katja Beesdo-Baum
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Street 46, 01187 Dresden, Germany
    J Psychiatr Res 45:962-72. 2011
    ..Developmental aspects require stronger consideration in future diagnostic systems...
  43. doi request reprint The role of parental psychopathology and family environment for social phobia in the first three decades of life
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    Depress Anxiety 26:363-70. 2009
    ..To examine the role of parental psychopathology and family environment for the risk of social phobia (SP) in offspring from childhood to early adulthood, encompassing the high risk period for SP...
  44. ncbi request reprint [Cardiovascular high-risk constellations in primary care. DETECT Study 2003]
    L Pieper
    Institut für Klinische Psychologie und Psychotherapie, Technische Universitat Dresden, Germany
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 48:1374-82. 2005
    ..The study describes for the first time in greater detail the prevalence of specific disorders and the frequency of high-risk constellations in primary care and allows for the evaluation of various risk scores...
  45. ncbi request reprint Aims, design and methods of the Smoking and Nicotine Dependence Awareness and Screening (SNICAS) study
    Stephan Muehlig
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
    Int J Methods Psychiatr Res 12:208-28. 2003
    ..This paper provides an overview of the design and methods of the study, informs about sampling and response rates, and examines whether the study sample could be considered representative of German primary care doctors...
  46. ncbi request reprint DSM-IV pain disorder in the general population. An exploration of the structure and threshold of medically unexplained pain symptoms
    Christine Frohlich
    Technische Universitat Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    Eur Arch Psychiatry Clin Neurosci 256:187-96. 2006
    ..Despite an abundance of questionnaire data, the prevalence of clinically significant and medically unexplained pain syndromes in the general population has rarely been examined with a rigid personal-interview methodology...
  47. ncbi request reprint Where have they been? Service use of regular substance users with and without abuse and dependence
    Axel Perkonigg
    Technische Universitat Dresden, Dresden, Germany
    Soc Psychiatry Psychiatr Epidemiol 41:470-9. 2006
    ..To present lifetime rates of service use for psychological and substance use related problems among regular substance users and to examine factors associated with service use...
  48. doi request reprint Depression does not affect the treatment outcome of CBT for panic and agoraphobia: results from a multicenter randomized trial
    Angela Emmrich
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Psychother Psychosom 81:161-72. 2012
    ....
  49. doi request reprint Maternal anxiety disorders prior to conception, psychopathology during pregnancy and early infants' development: a prospective-longitudinal study
    Julia Martini
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Straße 46, 01187, Dresden, Germany
    Arch Womens Ment Health 16:549-60. 2013
    ..Results are expected to provide new insights into mechanisms of familial transmission and clues for targeted prevention and early intervention. ..
  50. doi request reprint Binary regression: total gain in positive and negative predictive values
    Jens Klotsche
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Strasse 46, 01187 Dresden, Germany
    Biom J 54:808-23. 2012
    ..Both measures provide a useful tool for assessing the performance or accuracy of a set of predictor variables for the prediction of a binary outcome. This concept is a tool for evaluating the optimal prediction model in future research...
  51. ncbi request reprint Size and burden of social phobia in Europe
    Lydia Fehm
    Department of Psychology, Humboldt University Berlin, Rudower Chaussee 18, D 12489 Berlin, Germany
    Eur Neuropsychopharmacol 15:453-62. 2005
    ..No data are available addressing met and unmet needs for intervention and costs, and data for vulnerability and risk factors of malignant course are scarce...
  52. doi request reprint Posttraumatic stress disorder and obesity: evidence for a risk association
    Axel Perkonigg
    Department of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
    Am J Prev Med 36:1-8. 2009
    ..The aim of this study was to examine prospective longitudinal associations between PTSD and obesity in a community sample...
  53. doi request reprint Long-term stability of cognitive behavioral therapy effects for panic disorder with agoraphobia: a two-year follow-up study
    Andrew T Gloster
    Technische Universitat Dresden, Institute of Clinical Psychology and Psychotherapy, Germany University of Basel, Department of Psychology, Division of Clinical Psychology and Epidemiology, Switzerland Electronic address
    Behav Res Ther 51:830-9. 2013
    ..Cognitive-behavioral therapy (CBT) aims to help patients establish new behaviors that will be maintained and adapted to the demands of new situations. The long-term outcomes are therefore crucial in testing the durability of CBT...
  54. ncbi request reprint Frequency of albuminuria in primary care: a cross-sectional study
    Peter Bramlage
    Institute for Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
    Eur J Cardiovasc Prev Rehabil 14:107-13. 2007
    ....
  55. ncbi request reprint Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled
    Peter Bramlage
    Institute of Clinical Pharmacology, Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden
    Am J Hypertens 17:904-10. 2004
    ..The objective of this study was to assess the prevalence of hypertension and the diagnosis, treatment status, and control rates of hypertension in obese patients as compared to patients with normal weight...
  56. doi request reprint Psychometric properties of the Retrospective Self Report of Inhibition (RSRI) in a representative German sample
    Heike Rohrbacher
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, Germany
    Int J Methods Psychiatr Res 17:80-8. 2008
    ..The psychometric properties of the German RSRI were found to be comparable to those of the English version. The applicability of this questionnaire in German-speaking countries is therefore recommended for adolescents and young adults...
  57. doi request reprint Re-examining the differential familial liability of agoraphobia and panic disorder
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Tech nische Universitaet, Dresden, Germany
    Depress Anxiety 29:931-8. 2012
    ..Convincing evidence for either position notably requires considering also other anxiety disorders to establish the position of AG relative to the panic/anxiety spectrum...
  58. doi request reprint Risk and speed of transitions to first alcohol dependence symptoms in adolescents: a 10-year longitudinal community study in Germany
    Silke Behrendt
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Addiction 103:1638-47. 2008
    ..It is unclear whether early onset of AU is associated with the speed of transition to first AD symptoms and whether specific first AD symptoms and their timing are associated with AD...
  59. doi request reprint Anxiety disorders before birth and self-perceived distress during pregnancy: associations with maternal depression and obstetric, neonatal and early childhood outcomes
    Julia Martini
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet, Dresden, Germany
    Early Hum Dev 86:305-10. 2010
    ..However, studies considering the effect of DSM-IV anxiety disorders beyond maternal self-perceived distress during pregnancy and its timing are lacking...
  60. doi request reprint Trajectory classes of decline in health-related quality of life in Parkinson's disease: a pilot study
    Jens Klotsche
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
    Value Health 14:329-38. 2011
    ..To analyze the change in health-related quality-of-life (HRQoL) in patients with Parkinson's disease (PD) and to identify different classes of HRQoL decline...
  61. doi request reprint Timing matters: change depends on the stage of treatment in cognitive behavioral therapy for panic disorder with agoraphobia
    Andrew T Gloster
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden
    J Consult Clin Psychol 82:141-53. 2014
    ..The relative importance of these process variables was examined across treatment phases: (a) psychoeducation/interoceptive exposure, (b) in situ exposure, and (c) generalization/follow-up...
  62. doi request reprint The design and methods of the mental health module in the German Health Interview and Examination Survey for Adults (DEGS1-MH)
    Frank Jacobi
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
    Int J Methods Psychiatr Res 22:83-99. 2013
    ....
  63. doi request reprint The natural course of cannabis use, abuse and dependence during the first decades of life
    Axel Perkonigg
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
    Addiction 103:439-49; discussion 450-1. 2008
    ..The current study estimated rates and risk factors associated with stability and variation in cannabis use patterns, cannabis abuse and cannabis dependence in a community sample over a 10-year period...
  64. ncbi request reprint Estimating causal effects from observational data with a model for multiple bias
    Michael Hofler
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46a, 01187 Dresden, Germany
    Int J Methods Psychiatr Res 16:77-87. 2007
    ..Multiple bias modelling, if properly used, reveals the necessity for a better understanding of bias, suggesting a need to conduct larger and more adequate validation studies on instruments that are used to diagnose mental disorders...
  65. doi request reprint Premenstrual symptoms are associated with psychological and physical symptoms in early pregnancy
    Susanne Winkel
    Technische Universitat Dresden, Institute for Clinical Psychology and Psychotherapy, Chemnitzer Str 46, 01178 Dresden, Germany
    Arch Womens Ment Health 16:109-15. 2013
    ..The findings further imply that the nature of symptoms might be rather consistent between different reproductive phases...
  66. doi request reprint Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)
    Oliver Riedel
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
    J Neurol 255:255-64. 2008
    ..Prevalence estimates of these complications are quite variable and are lacking for the outpatient care sector...
  67. doi request reprint Characterizing the association between parenting and adolescent social phobia
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
    J Anxiety Disord 26:608-16. 2012
    ..paternal contributions, putative predictors of unfavorable parenting behaviors and its specificity for SP are warranted to delineate targeted prevention and intervention strategies...
  68. doi request reprint (Don't) panic in the scanner! How panic patients with agoraphobia experience a functional magnetic resonance imaging session
    Ulrike Lueken
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Eur Neuropsychopharmacol 21:516-25. 2011
    ..Future studies are needed to investigate the relationship between self-reported distress and fMRI data in patient groups that are subject to neuroimaging research...
  69. ncbi request reprint Prevalence, recognition and management of depression in primary care in Germany: the Depression 2000 study
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy and Technical University of Dresden, Dresden, Germany
    Hum Psychopharmacol 17:S1-11. 2002
    ..It remains of continued prime importance to educate primary care doctors to better recognise depression in order to increase the patients' chances of receiving appropriate treatment...
  70. doi request reprint Association between generalized anxiety levels and pain in a community sample: evidence for diagnostic specificity
    Katja Beesdo
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    J Anxiety Disord 23:684-93. 2009
    ..It is unclear whether generalized anxiety disorder (GAD) has a specific relationship to pain syndromes, going beyond the established association of pain with anxiety syndromes in general...
  71. ncbi request reprint [Diagnosing mental disorders: gold or tin standard?--Critical comments on standardized diagnostic interviews and clinical routine diagnoses]
    Susanne Knappe
    Institut für Klinische Psychologie und Psychotherapie, Technische Universitat Dresden, Dresden
    Psychother Psychosom Med Psychol 58:72-5. 2008
    ..do not justify this conclusion. Aside from substantial methodological deficits, we question the authors' assumption that clinical diagnoses could be regarded as an appropriate "gold standard"...
  72. doi request reprint How specific is specific phobia? Different neural response patterns in two subtypes of specific phobia
    Ulrike Lueken
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, 01187 Dresden, Germany
    Neuroimage 56:363-72. 2011
    ..If replicated, results could contribute to a better understanding of underlying neurobiological mechanisms of specific phobia and their respective classification...
  73. pmc Associations of familial risk factors with social fears and social phobia: evidence for the continuum hypothesis in social anxiety disorder?
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    J Neural Transm 116:639-48. 2009
    ..Parental psychopathology and negative parental styles may be used defining high-risk groups to assign individuals with already subthreshold conditions of SAD to early intervention programs...
  74. doi request reprint The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trials
    Katja Beesdo
    Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    J Anxiety Disord 23:1064-71. 2009
    ..02). In conclusion, duloxetine was efficacious in the short- and long-term treatment of PPS, which are common in GAD patients...
  75. ncbi request reprint Association chain graphs: modelling etiological pathways
    Michael Hofler
    Technical University Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    Int J Methods Psychiatr Res 12:77-84. 2003
    ..With this new type of graph, more specific information can be displayed whenever the data are essentially described only with statistical main- and two-way interaction effects...
  76. ncbi request reprint The accuracy of prevalence estimations for suicide attempts. how reliably do adolescents and young adults report their suicide attempts?
    Bettina Christl
    Dresden University of Technology, Clinical Psychology and Psychotherapy
    Arch Suicide Res 10:253-63. 2006
    ..One-third of all baseline suicide attempters did not report their suicide attempt again at the four years later assessment. In particular, 80% of all nonreporters were female, and almost 60% were aged 14-17 at baseline...
  77. ncbi request reprint Accuracy of anthropometric indicators of obesity to predict cardiovascular risk
    Harald J Schneider
    Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden, Germany
    J Clin Endocrinol Metab 92:589-94. 2007
    ..However, more recently, waist to hip ratio (WHR) or waist circumference (WC) as more sensitive measures for visceral obesity have been proposed to be more indicative of cardiovascular risk...
  78. doi request reprint Psychological treatment for panic disorder with agoraphobia: a randomized controlled trial to examine the role of therapist-guided exposure in situ in CBT
    Andrew T Gloster
    Institute for Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, Germany
    J Consult Clin Psychol 79:406-20. 2011
    ..This study was aimed to evaluate whether therapist-guided exposure in situ is associated with more pervasive and long-lasting effects than therapist-prescribed exposure in situ...
  79. pmc A novel nonparametric approach for estimating cut-offs in continuous risk indicators with application to diabetes epidemiology
    Jens Klotsche
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
    BMC Med Res Methodol 9:63. 2009
    ..The cut-off corresponding to the Youden-Index is often applied in epidemiology and biomedical literature for dichotomizing a continuous risk indicator...
  80. doi request reprint Do parental psychopathology and unfavorable family environment predict the persistence of social phobia?
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    J Anxiety Disord 23:986-94. 2009
    ..Predictors for SP persistence differ from those predicting SP onset. Unfavorable family environment alone and in interaction with parental disorders predict higher SP persistence...
  81. ncbi request reprint Generalized anxiety disorder: prevalence, burden, and cost to society
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    Depress Anxiety 16:162-71. 2002
    ....
  82. doi request reprint The scanner as a stressor: evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging session
    Markus Muehlhan
    Chair of Biopsychology, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Int J Psychophysiol 79:118-26. 2011
    ..No significant correlation between cortisol and thalamic activity was observed. Results indicate that an fMRI experiment may elicit subjective and neuroendocrine stress reactions that can influence functional activation patterns...
  83. doi request reprint Familial risk factors in social anxiety disorder: calling for a family-oriented approach for targeted prevention and early intervention
    Susanne Knappe
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
    Eur Child Adolesc Psychiatry 19:857-71. 2010
    ..This review sets out to develop a more family-oriented approach for predicting the onset and maintenance of SAD that may be fruitful to derive targeted prevention and early intervention in SAD...
  84. doi request reprint Why people change? The role of cognitive-control processes in the onset and cessation of substance abuse disorders
    Gerhard Buhringer
    Chair of Addiction Research, Institute of Clinical, Diagnostic and Differential Psychology, Technische Universitaet Dresden, Germany
    Int J Methods Psychiatr Res 17:S4-S15. 2008
    ..Progress in understanding the processes related to the onset, course, and cessation of SUDs merits top priority, given the high prevalence and the severe negative consequences...
  85. ncbi request reprint Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS)
    F Jacobi
    Institute of Clinical Psychology and Psychotherapy, Unit Epidemiology and Service Research, Technical University of Dresden, Germany
    Psychol Med 34:597-611. 2004
    ..This paper reports results from its Mental Health Supplement (GHS-MHS) on 4-week 12-month, and selected lifetime prevalence of a broad range of DSM-IV mental disorders, their co-morbidity and correlates in the community...
  86. doi request reprint Symptom provocation in dental anxiety using cross-phobic video stimulation
    Ulrike Lueken
    Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Eur J Oral Sci 119:61-8. 2011
    ..The validation of the paradigm may support and stimulate future research on the characterization of dental anxiety on different response systems, including its underlying neural substrates...
  87. doi request reprint New women-specific diagnostic modules: the Composite International Diagnostic Interview for Women (CIDI-VENUS)
    Julia Martini
    Technische Universitat Dresden, Dresden, Germany
    Arch Womens Ment Health 12:281-9. 2009
    ....
  88. pmc Common and distinct amygdala-function perturbations in depressed vs anxious adolescents
    Katja Beesdo
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Strasse 46, Dresden, Germany
    Arch Gen Psychiatry 66:275-85. 2009
    ..Few studies directly compare amygdala function in depressive and anxiety disorders. Data from longitudinal research emphasize the need for such studies in adolescents...
  89. ncbi request reprint [The use of guidelines in the primary care management of hypertension and diabetes]
    Nicole Wagner
    Institut für Klinische Pharmakologie und Forschungsverbund Public Health Sachsen und Sachsen Anhalt e V, TU Dresden
    Soz Praventivmed 49:261-8. 2004
    ..The paper examines to what degree German primary care physicians know and work along the rules established in guidelines for arterial hypertension and diabetes mellitus...
  90. doi request reprint Effectiveness of day hospital treatment for anorexia nervosa and bulimia nervosa
    Eike Fittig
    Unit for Eating Disorders Research, Institute of Clinical Psychology, Technical University of Dresden, Germany
    Eur Eat Disord Rev 16:341-51. 2008
    ..The results demonstrate both the short-term effectiveness and long-term stability of day hospital treatment in a large sample of patients with anorexia and BN...
  91. ncbi request reprint Patterns of antihypertensive drug utilization in primary care
    D Pittrow
    Institute of Clinical Pharmacology, Technical University, Fiedlerstrasse 27, 01307 Dresden, Germany
    Eur J Clin Pharmacol 60:135-42. 2004
    ..Thus, current use of antihypertensive drugs in primary care was analyzed and the association with selected physician and patient characteristics was assessed...
  92. ncbi request reprint Diabetes and cardiovascular risk evaluation and management in primary care: progress and unresolved issues - rationale for a nationwide primary care project in Germany
    S Bohler
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 112:157-70. 2004
    ..Based on this, a large-scale epidemiological investigation focusing on CHD and diabetes in the primary care sector is suggested...
  93. ncbi request reprint Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in Germany
    S Bohler
    Institute for Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    Atherosclerosis 190:397-407. 2007
    ..Coronary artery disease (CAD), risk categories and LDL-C target achievement rates were determined in the subset of 6815 patients according to the National Cholesterol Education Program (NCEP) ATP III Guidelines...
  94. doi request reprint [Depression as a comorbid disorder in primary care]
    L Pieper
    Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 51:411-21. 2008
    ..Further the association with health related quality of life and disability is examined. Depression was assessed with the Depression Screening Questionnaire (DSQ) with an ICD-10 algorithm...
  95. ncbi request reprint [Mental disorders in the community: healthcare utilization and disability days]
    F Jacobi
    Institut für Klinische Psychologie und Psychotherapie, AG, Technische Universitat Dresden, Dresden
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:736-44. 2004
    ..The results are consistent with the episodic course of many mental disorders and furthermore might indicate that treatment of mental disorders might contribute to a substantial reduction of direct and indirect illness costs...
  96. ncbi request reprint Recognition and management of overweight and obesity in primary care in Germany
    P Bramlage
    Institute of Clinical Psychology and Psychotherapy, Technical University, 01187 Dresden, Germany
    Int J Obes Relat Metab Disord 28:1299-308. 2004
    ....
  97. ncbi request reprint [How do risk patients with overweight/obesity differ in their health knowledge and behaviour from patients with normal weight? A study in primary medical care]
    B Kupper
    Institut für Klinische Psychologie und Psychotherapie, Technische Universitat Dresden
    Gesundheitswesen 66:361-9. 2004
    ..Therefore, we investigated whether these patients are more aware of health-related issues and problems than normal-weight patient with data from the HYDRA study on 45,000 subjects...
  98. doi request reprint A striking pattern of cortisol non-responsiveness to psychosocial stress in patients with panic disorder with concurrent normal cortisol awakening responses
    Katja Petrowski
    Institute of Psychotherapy and Psychosomatic Medicine, School of Medicine, Technische Universitat Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Psychoneuroendocrinology 35:414-21. 2010
    ..While these patients show little or no alterations in basal ACTH and cortisol levels, it has been hypothesized that HPA hyperresponsivity was a trait in panic patients when exposed to novel and uncontrollable stimulation...
  99. ncbi request reprint Trauma and PTSD - an overlooked pathogenic pathway for premenstrual dysphoric disorder?
    H U Wittchen
    Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
    Arch Womens Ment Health 6:293-7. 2003
    ..A recent epidemiological analysis on premenstrual dysphoric disorder (PMDD) in the community revealed increased rates of DSM-IV posttraumatic stress disorder (PTSD) among women suffering from PMDD...
  100. ncbi request reprint Maternal suicidality and risk of suicidality in offspring: findings from a community study
    Roselind Lieb
    Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology Unit, Kraepelinstr 2, 80804 München, Germany
    Am J Psychiatry 162:1665-71. 2005
    ..This study evaluated the associations between suicidal ideation and suicide attempts in mothers and various aspects of suicidality in their offspring in a representative community sample...
  101. ncbi request reprint Life events and changes in the course of depression in young adults
    Robert H Friis
    Department of Health Science, California State University, Long Beach, CA, USA
    Eur Psychiatry 17:241-53. 2002
    ..Few community-based studies have examined the impact of life events, life conditions and life changes on the course of depression. This paper examines associations of life events on depressive symptom onset, improvement, and stability...