Research Topics
| Hans Ulrich WittchenSummaryAffiliation: Technical University Country: Germany Publications
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Publications
Traumatic experiences and posttraumatic stress disorder in soldiers following deployment abroad: how big is the hidden problem?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies, Technische Universitat Dresden, Dresden, Germany
Dtsch Arztebl Int 109:559-68. 2012..Little is known about the frequency of traumatic event exposure and the development of post-traumatic stress disorder (PTSD) among German soldiers serving in Afghanistan...
[Generalized anxiety disorder in primary care. Patterns of healthcare utilization in Germany]H U Wittchen
Technische Universitat Dresden, Deutschland
MMW Fortschr Med 154:77-84. 2012..Generalized Anxiety Disorder (GAD) has been described in community studies as a frequent and costly high utilizer group in the primary care sector. Administrative data supporting this observation are lacking so far...
Omalizumab versus 'usual care': results from a naturalistic longitudinal study in routine careH U Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Int Arch Allergy Immunol 159:83-93. 2012..It is unclear how far the superior efficacy of omalizumab, established in randomized controlled clinical trials of patients with severe allergic asthma (SAA), translates into routine practice and when compared to matched controls...
Prevalence, incidence and determinants of PTSD and other mental disorders: design and methods of the PID-PTSD+3 studyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Int J Methods Psychiatr Res 21:98-116. 2012..We expect the findings to advance our understanding of a wide spectrum of adverse mental health outcomes beyond PTSD...
Social Phobia in an Italian region: do Italian studies show lower frequencies than community surveys conducted in other European countries?Mauro Giovanni Carta
Division of Psychiatry, Department of Public Health, University of Cagliari, Italy
BMC Psychiatry 4:31. 2004..5% to 16.0%. The aim of this study was to assess the frequency of SP in Sardinia (Italy) in order to verify the evidence of a lower frequency of SP in Italy observed in previous studies (from 1.0% to 3.1%)...
Depressive episodes--evidence for a causal role of primary anxiety disorders?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Dresden University of Technology, Chemnitzerstrasse 46, 01187 Dresden, Germany
Eur Psychiatry 18:384-93. 2003..The goal of this paper is to review recent literature, summarize implications of previous findings, and suggest directions for future research regarding preventive and intervention strategies...
The position of anxiety disorders in structural models of mental disordersHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universita t Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
Psychiatr Clin North Am 32:465-81. 2009..Extant results are not stable enough to form the basis of clinical diagnostic classification systems such as DSM and the International Classification of Diseases...
Developments in the treatment and diagnosis of anxiety disordersHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Strasse 46, D 01187 Dresden, Germany
Psychiatr Clin North Am 32:xiii-xix. 2009..This article reviews these critical issues and sets the stage for the other articles in this special issue...
Natural course and burden of bipolar disordersHans Ulrich Wittchen
Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy D 01062 Dresden, Germany
Int J Neuropsychopharmacol 6:145-54. 2003..iii) The value of both types of studies might be enhanced, if beyond the use of standardized diagnostic interview, special attempts are made to use prospective life- and episode-charting methods for bipolar illnesses...
Women-specific mental disorders in DSM-V: are we failing again?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
Arch Womens Ment Health 13:51-5. 2010....
Posttraumatic stress disorder: diagnostic and epidemiological perspectivesHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
CNS Spectr 14:5-12. 2009..A further exploitation of the existing data, and an improvement of existing epidemiological methods, strategies, and assessments are likely to substantially contribute to the clarification of unresolved diagnostic issues...
Agoraphobia: a review of the diagnostic classificatory position and criteriaHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, D 01187Dresden, Germany
Depress Anxiety 27:113-33. 2010....
Agoraphobia and panic. Prospective-longitudinal relations suggest a rethinking of diagnostic conceptsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychother Psychosom 77:147-57. 2008..The aim of the current study is to prospectively examine the 10-year natural course of PA, PD and AG in the first three decades of life, their stability and their reciprocal transitions...
Smoking cessation in primary care - a randomized controlled trial of bupropione, nicotine replacements, CBT and a minimal interventionHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Int J Methods Psychiatr Res 20:28-39. 2011..Smoking cessation has been shown to be effective in randomized controlled trials. It is unclear though, whether interventions also work in routine primary care...
The size and burden of mental disorders and other disorders of the brain in Europe 2010H U Wittchen
Institute of Clinical Psychology and Psychotherapy, Center of Epidemiology and Longitudinal Studies CELOS, Technische Universitat Dresden, Dresden, Germany
Eur Neuropsychopharmacol 21:655-79. 2011....
Buprenorphine and methadone in the treatment of opioid dependence: methods and design of the COBRA studyHans Ulrich Wittchen
Institut für Klinische Psychologie und Psychotherapie, TU Dresden, Germany
Int J Methods Psychiatr Res 14:14-28. 2005..The COBRA study provides a unique comprehensive database, informing about the natural allocation and intervention processes in routine care and about the course and outcome of patients treated with buprenorphine or methadone...
Met and unmet needs in the management of depressive disorder in the community and primary care: the size and breadth of the problemH U Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
J Clin Psychiatry 62:23-8. 2001..With this management strategy, access to care can be broadened to include not only the severely ill, but also patients in earlier stages of their depressive illness process who might profit most from modern treatment methods...
Cardiovascular risk factors in primary care: methods and baseline prevalence rates--the DETECT programH U Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
Curr Med Res Opin 21:619-30. 2005....
Cannabis use and cannabis use disorders and their relationship to mental disorders: a 10-year prospective-longitudinal community study in adolescentsHans Ulrich Wittchen
Clinical Psychology and Psychotherapy, Technical University Dresden, D 01187 Dresden, Germany
Drug Alcohol Depend 88:S60-70. 2007..Whereas the role of externalizing disorders is relatively well established in predicting the onset of cannabis use (CU) or cannabis use disorder (CUD), the status of anxiety and mood disorders in predicting CU and CUD remains controversial...
The structure of mental disorders re-examined: is it developmentally stable and robust against additions?Hans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Int J Methods Psychiatr Res 18:189-203. 2009..However, again, there is little consistency in findings when different age groups or different diagnoses are considered. Our findings suggest that psychopathology cannot be reduced to any simple structure...
Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of lifeKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Arch Gen Psychiatry 64:903-12. 2007....
Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination SurveyFrank Jacobi
Institute of Clinical Psychology and Psychotherapy, Unit, Technical University of Dresden, Germany
Int J Methods Psychiatr Res 11:1-18. 2002..Overall, the GHS core survey and its mental health supplement provide the mental health research community with complex data that allow for high-quality analysis of mental disorders and associations with somatic disorders...
The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disordersSilke Behrendt
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, D 01187 Dresden, Germany
Drug Alcohol Depend 123:48-56. 2012..However, the cross-substance relationship between a younger age at onset of alcohol use (AU) and nicotine use (NU) and the risk of cannabis use disorders (CUD) in adolescence and early adulthood remains unclear...
The structure of common mental disorders: a replication study in a community sample of adolescents and young adultsKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Int J Methods Psychiatr Res 18:204-20. 2009....
Pain associated with specific anxiety and depressive disorders in a nationally representative population sampleKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187, Dresden, Germany
Soc Psychiatry Psychiatr Epidemiol 45:89-104. 2010....
Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's diseaseOliver Riedel
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
J Neurol 257:1073-82. 2010..PD outpatients are at an increased risk for all neuropsychiatric conditions, increasing with PD severity but not with age or age of onset (except dementia), revealing challenging symptom patterns...
Incidence and risk patterns of anxiety and depressive disorders and categorization of generalized anxiety disorderKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer St 46, 01187 Dresden, Germany
Arch Gen Psychiatry 67:47-57. 2010..Controversy surrounds the diagnostic categorization of generalized anxiety disorder (GAD)...
What characteristics of primary anxiety disorders predict subsequent major depressive disorder?Antje Bittner
Department of Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany
J Clin Psychiatry 65:618-26, quiz 730. 2004....
Occurrence risk and structure of depression in Parkinson disease with and without dementia: results from the GEPAD StudyOliver Riedel
Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
J Geriatr Psychiatry Neurol 23:27-34. 2010....
Generalized anxiety and depression in primary care: prevalence, recognition, and managementHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
J Clin Psychiatry 63:24-34. 2002....
Social fear and social phobia types among community youth: differential clinical features and vulnerability factorsSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
J Psychiatr Res 45:111-20. 2011....
Size and burden of mental disorders in Europe--a critical review and appraisal of 27 studiesHans Ulrich Wittchen
Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Eur Neuropsychopharmacol 15:357-76. 2005..These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations...
A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life: Evidence for heterogeneity and different treatment needsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, D 01187 Dresden, Germany
Drug Alcohol Depend 102:151-7. 2009..Cannabis use (CU) and disorders (CUD) are highly prevalent among adolescents and young adults. We aim to identify clinically meaningful latent classes of users of cannabis and other illegal substances with distinct problem profiles...
Substance use and substance use disorders in a community sample of adolescents and young adults: incidence, age effects and patterns of useAxel Perkonigg
Department of Clinical Psychology and Psychotherapy, Dresden University of Technology, Dresden, Germany
Eur Addict Res 12:187-96. 2006..Patterns of onset, cohort trends, and use of various substance classes are also analyzed...
Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patientsHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzerstrasse 46, 01187 Dresden, Germany
Drug Alcohol Depend 95:245-57. 2008..Despite many short-term studies, little is known about the long-term (12-month) effects of these treatments in different settings, i.e. primary care-based (PMC) and specialized substitution centers (SSCs)...
[Prevalence, drug treatment and metabolic control of diabetes mellitus in primary care]David Pittrow
Institut fur Klinische Pharmakologie, Forschungsverbund Public Health, Technische Universitat Dresden, Dresden, Germany
Med Klin (Munich) 101:635-44. 2006....
The diagnostic threshold of generalized anxiety disorder in the community: a developmental perspectiveKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Street 46, 01187 Dresden, Germany
J Psychiatr Res 45:962-72. 2011..Developmental aspects require stronger consideration in future diagnostic systems...
Where have they been? Service use of regular substance users with and without abuse and dependenceAxel Perkonigg
Technische Universitat Dresden, Dresden, Germany
Soc Psychiatry Psychiatr Epidemiol 41:470-9. 2006..To present lifetime rates of service use for psychological and substance use related problems among regular substance users and to examine factors associated with service use...
DSM-IV pain disorder in the general population. An exploration of the structure and threshold of medically unexplained pain symptomsChristine Frohlich
Technische Universitat Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
Eur Arch Psychiatry Clin Neurosci 256:187-96. 2006..Despite an abundance of questionnaire data, the prevalence of clinically significant and medically unexplained pain syndromes in the general population has rarely been examined with a rigid personal-interview methodology...
The role of parental psychopathology and family environment for social phobia in the first three decades of lifeSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Depress Anxiety 26:363-70. 2009..To examine the role of parental psychopathology and family environment for the risk of social phobia (SP) in offspring from childhood to early adulthood, encompassing the high risk period for SP...
[Cardiovascular high-risk constellations in primary care. DETECT Study 2003]L Pieper
, , Germany
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 48:1374-82. 2005..The study describes for the first time in greater detail the prevalence of specific disorders and the frequency of high-risk constellations in primary care and allows for the evaluation of various risk scores...
Depression does not affect the treatment outcome of CBT for panic and agoraphobia: results from a multicenter randomized trialAngela Emmrich
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Psychother Psychosom 81:161-72. 2012....
Size and burden of social phobia in EuropeLydia Fehm
Department of Psychology, Humboldt University Berlin, Rudower Chaussee 18, D 12489 Berlin, Germany
Eur Neuropsychopharmacol 15:453-62. 2005..No data are available addressing met and unmet needs for intervention and costs, and data for vulnerability and risk factors of malignant course are scarce...
Posttraumatic stress disorder and obesity: evidence for a risk associationAxel Perkonigg
Department of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Am J Prev Med 36:1-8. 2009..The aim of this study was to examine prospective longitudinal associations between PTSD and obesity in a community sample...
Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlledPeter Bramlage
Institute of Clinical Pharmacology, Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden
Am J Hypertens 17:904-10. 2004..The objective of this study was to assess the prevalence of hypertension and the diagnosis, treatment status, and control rates of hypertension in obese patients as compared to patients with normal weight...
Frequency of albuminuria in primary care: a cross-sectional studyPeter Bramlage
Institute for Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
Eur J Cardiovasc Prev Rehabil 14:107-13. 2007....
Psychometric properties of the Retrospective Self Report of Inhibition (RSRI) in a representative German sampleHeike Rohrbacher
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, Germany
Int J Methods Psychiatr Res 17:80-8. 2008..The psychometric properties of the German RSRI were found to be comparable to those of the English version. The applicability of this questionnaire in German-speaking countries is therefore recommended for adolescents and young adults...
Prevalence, recognition and management of depression in primary care in Germany: the Depression 2000 studyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy and Technical University of Dresden, Dresden, Germany
Hum Psychopharmacol 17:S1-11. 2002..It remains of continued prime importance to educate primary care doctors to better recognise depression in order to increase the patients' chances of receiving appropriate treatment...
Estimating causal effects from observational data with a model for multiple biasMichael Hofler
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46a, 01187 Dresden, Germany
Int J Methods Psychiatr Res 16:77-87. 2007..Multiple bias modelling, if properly used, reveals the necessity for a better understanding of bias, suggesting a need to conduct larger and more adequate validation studies on instruments that are used to diagnose mental disorders...
Trajectory classes of decline in health-related quality of life in Parkinson's disease: a pilot studyJens Klotsche
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Dresden, Germany
Value Health 14:329-38. 2011..To analyze the change in health-related quality-of-life (HRQoL) in patients with Parkinson's disease (PD) and to identify different classes of HRQoL decline...
Anxiety disorders before birth and self-perceived distress during pregnancy: associations with maternal depression and obstetric, neonatal and early childhood outcomesJulia Martini
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet, Dresden, Germany
Early Hum Dev 86:305-10. 2010..However, studies considering the effect of DSM-IV anxiety disorders beyond maternal self-perceived distress during pregnancy and its timing are lacking...
The natural course of cannabis use, abuse and dependence during the first decades of lifeAxel Perkonigg
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
Addiction 103:439-49; discussion 450-1. 2008..The current study estimated rates and risk factors associated with stability and variation in cannabis use patterns, cannabis abuse and cannabis dependence in a community sample over a 10-year period...
Risk and speed of transitions to first alcohol dependence symptoms in adolescents: a 10-year longitudinal community study in GermanySilke Behrendt
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Germany
Addiction 103:1638-47. 2008..It is unclear whether early onset of AU is associated with the speed of transition to first AD symptoms and whether specific first AD symptoms and their timing are associated with AD...
Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD)Oliver Riedel
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Chemnitzer Strasse 46, Dresden, Germany
J Neurol 255:255-64. 2008..Prevalence estimates of these complications are quite variable and are lacking for the outpatient care sector...
Characterizing the association between parenting and adolescent social phobiaSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
J Anxiety Disord 26:608-16. 2012..paternal contributions, putative predictors of unfavorable parenting behaviors and its specificity for SP are warranted to delineate targeted prevention and intervention strategies...
(Don't) panic in the scanner! How panic patients with agoraphobia experience a functional magnetic resonance imaging sessionUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
Eur Neuropsychopharmacol 21:516-25. 2011..Future studies are needed to investigate the relationship between self-reported distress and fMRI data in patient groups that are subject to neuroimaging research...
Associations of familial risk factors with social fears and social phobia: evidence for the continuum hypothesis in social anxiety disorder?Susanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
J Neural Transm 116:639-48. 2009..Parental psychopathology and negative parental styles may be used defining high-risk groups to assign individuals with already subthreshold conditions of SAD to early intervention programs...
[Diagnosing mental disorders: gold or tin standard?--Critical comments on standardized diagnostic interviews and clinical routine diagnoses]Susanne Knappe
Institut für Klinische Psychologie und Psychotherapie, Technische Universitat Dresden, Dresden
Psychother Psychosom Med Psychol 58:72-5. 2008..do not justify this conclusion. Aside from substantial methodological deficits, we question the authors' assumption that clinical diagnoses could be regarded as an appropriate "gold standard"...
How specific is specific phobia? Different neural response patterns in two subtypes of specific phobiaUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, 01187 Dresden, Germany
Neuroimage 56:363-72. 2011..If replicated, results could contribute to a better understanding of underlying neurobiological mechanisms of specific phobia and their respective classification...
Association between generalized anxiety levels and pain in a community sample: evidence for diagnostic specificityKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
J Anxiety Disord 23:684-93. 2009..It is unclear whether generalized anxiety disorder (GAD) has a specific relationship to pain syndromes, going beyond the established association of pain with anxiety syndromes in general...
The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trialsKatja Beesdo
Technische Universitaet Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
J Anxiety Disord 23:1064-71. 2009..02). In conclusion, duloxetine was efficacious in the short- and long-term treatment of PPS, which are common in GAD patients...
Psychometric properties of the dimensional anxiety scales for DSM-V in an unselected sample of German treatment seeking patientsKatja Beesdo-Baum
Institute of Clinical Psychology and Psychotherapy, Tech nische Universitaet Dresden, Germany
Depress Anxiety 29:1014-24. 2012..These scales use a common template to assess core constructs of fear and anxiety...
Association chain graphs: modelling etiological pathwaysMichael Hofler
Technical University Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
Int J Methods Psychiatr Res 12:77-84. 2003..With this new type of graph, more specific information can be displayed whenever the data are essentially described only with statistical main- and two-way interaction effects...
The accuracy of prevalence estimations for suicide attempts. how reliably do adolescents and young adults report their suicide attempts?Bettina Christl
Dresden University of Technology, Clinical Psychology and Psychotherapy
Arch Suicide Res 10:253-63. 2006..One-third of all baseline suicide attempters did not report their suicide attempt again at the four years later assessment. In particular, 80% of all nonreporters were female, and almost 60% were aged 14-17 at baseline...
Accuracy of anthropometric indicators of obesity to predict cardiovascular riskHarald J Schneider
Institute of Clinical Psychology and Psychotherapy, Technical University, Dresden, Germany
J Clin Endocrinol Metab 92:589-94. 2007..However, more recently, waist to hip ratio (WHR) or waist circumference (WC) as more sensitive measures for visceral obesity have been proposed to be more indicative of cardiovascular risk...
Psychological treatment for panic disorder with agoraphobia: a randomized controlled trial to examine the role of therapist-guided exposure in situ in CBTAndrew T Gloster
Institute for Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, Germany
J Consult Clin Psychol 79:406-20. 2011..This study was aimed to evaluate whether therapist-guided exposure in situ is associated with more pervasive and long-lasting effects than therapist-prescribed exposure in situ...
A novel nonparametric approach for estimating cut-offs in continuous risk indicators with application to diabetes epidemiologyJens Klotsche
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
BMC Med Res Methodol 9:63. 2009..The cut-off corresponding to the Youden-Index is often applied in epidemiology and biomedical literature for dichotomizing a continuous risk indicator...
Do parental psychopathology and unfavorable family environment predict the persistence of social phobia?Susanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
J Anxiety Disord 23:986-94. 2009..Predictors for SP persistence differ from those predicting SP onset. Unfavorable family environment alone and in interaction with parental disorders predict higher SP persistence...
Generalized anxiety disorder: prevalence, burden, and cost to societyHans Ulrich Wittchen
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
Depress Anxiety 16:162-71. 2002....
Why people change? The role of cognitive-control processes in the onset and cessation of substance abuse disordersGerhard Buhringer
Chair of Addiction Research, Institute of Clinical, Diagnostic and Differential Psychology, Technische Universitaet Dresden, Germany
Int J Methods Psychiatr Res 17:S4-S15. 2008..Progress in understanding the processes related to the onset, course, and cessation of SUDs merits top priority, given the high prevalence and the severe negative consequences...
Familial risk factors in social anxiety disorder: calling for a family-oriented approach for targeted prevention and early interventionSusanne Knappe
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str 46, 01187 Dresden, Germany
Eur Child Adolesc Psychiatry 19:857-71. 2010..This review sets out to develop a more family-oriented approach for predicting the onset and maintenance of SAD that may be fruitful to derive targeted prevention and early intervention in SAD...
The scanner as a stressor: evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging sessionMarkus Muehlhan
Chair of Biopsychology, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
Int J Psychophysiol 79:118-26. 2011..No significant correlation between cortisol and thalamic activity was observed. Results indicate that an fMRI experiment may elicit subjective and neuroendocrine stress reactions that can influence functional activation patterns...
Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS)F Jacobi
Institute of Clinical Psychology and Psychotherapy, Unit: Epidemiology and Service Research, Technical University of Dresden, Germany
Psychol Med 34:597-611. 2004..e. somatoform disorders, all anxiety disorders (except PTSD), mental disorders due to substance or general medical factor, eating disorders]. Intervention rates were higher than in previous studies, yet still low overall...
Symptom provocation in dental anxiety using cross-phobic video stimulationUlrike Lueken
Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
Eur J Oral Sci 119:61-8. 2011..The validation of the paradigm may support and stimulate future research on the characterization of dental anxiety on different response systems, including its underlying neural substrates...
New women-specific diagnostic modules: the Composite International Diagnostic Interview for Women (CIDI-VENUS)Julia Martini
Technische Universitat Dresden, Dresden, Germany
Arch Womens Ment Health 12:281-9. 2009....
Common and distinct amygdala-function perturbations in depressed vs anxious adolescentsKatja Beesdo
Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Strasse 46, Dresden, Germany
Arch Gen Psychiatry 66:275-85. 2009..Few studies directly compare amygdala function in depressive and anxiety disorders. Data from longitudinal research emphasize the need for such studies in adolescents...
Effectiveness of day hospital treatment for anorexia nervosa and bulimia nervosaEike Fittig
Unit for Eating Disorders Research, Institute of Clinical Psychology, Technical University of Dresden, Germany
Eur Eat Disord Rev 16:341-51. 2008..The results demonstrate both the short-term effectiveness and long-term stability of day hospital treatment in a large sample of patients with anorexia and BN...
[The use of guidelines in the primary care management of hypertension and diabetes]Nicole Wagner
Institut für Klinische Pharmakologie und Forschungsverbund Public Health Sachsen und Sachsen Anhalt e V, TU Dresden
Soz Praventivmed 49:261-8. 2004..The paper examines to what degree German primary care physicians know and work along the rules established in guidelines for arterial hypertension and diabetes mellitus...
Patterns of antihypertensive drug utilization in primary careD Pittrow
Institute of Clinical Pharmacology, Technical University, Fiedlerstrasse 27, 01307 Dresden, Germany
Eur J Clin Pharmacol 60:135-42. 2004..Thus, current use of antihypertensive drugs in primary care was analyzed and the association with selected physician and patient characteristics was assessed...
[How do risk patients with overweight/obesity differ in their health knowledge and behaviour from patients with normal weight? A study in primary medical care]B Kupper
Institut für Klinische Psychologie und Psychotherapie, Technische Universitat Dresden
Gesundheitswesen 66:361-9. 2004..Therefore, we investigated whether these patients are more aware of health-related issues and problems than normal-weight patient with data from the HYDRA study on 45,000 subjects...
Recognition and management of overweight and obesity in primary care in GermanyP Bramlage
Institute of Clinical Psychology and Psychotherapy, Technical University, 01187 Dresden, Germany
Int J Obes Relat Metab Disord 28:1299-308. 2004....
Diabetes and cardiovascular risk evaluation and management in primary care: progress and unresolved issues - rationale for a nationwide primary care project in GermanyS Bohler
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Exp Clin Endocrinol Diabetes 112:157-70. 2004..Based on this, a large-scale epidemiological investigation focusing on CHD and diabetes in the primary care sector is suggested...
[Depression as a comorbid disorder in primary care]L Pieper
Technische Universitat Dresden, Chemnitzer Strasse 46, Dresden, BRD
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 51:411-21. 2008..It is concluded that the degree to which the frequency and the deleterious effects of comorbid depression is underestimated and unrecognized is alarming. The use of comorbidity indices might improve recognition...
[Mental disorders in the community: healthcare utilization and disability days]F Jacobi
Institut für Klinische Psychologie und Psychotherapie, AG, Technische Universitat Dresden, Dresden
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:736-44. 2004..The results are consistent with the episodic course of many mental disorders and furthermore might indicate that treatment of mental disorders might contribute to a substantial reduction of direct and indirect illness costs...
Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in GermanyS Bohler
Institute for Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
Atherosclerosis 190:397-407. 2007..4% of the patients treated with lipid-lowering drugs) achieved their LDL-C treatment goals. In conclusion, 80.3% of patients in the sample with dyslipidemia went undiagnosed, un-treated or under-treated...
A striking pattern of cortisol non-responsiveness to psychosocial stress in patients with panic disorder with concurrent normal cortisol awakening responsesKatja Petrowski
Institute of Psychotherapy and Psychosomatic Medicine, School of Medicine, Technische Universitat Dresden, Fetscherstr 74, 01307 Dresden, Germany
Psychoneuroendocrinology 35:414-21. 2010..While these patients show little or no alterations in basal ACTH and cortisol levels, it has been hypothesized that HPA hyperresponsivity was a trait in panic patients when exposed to novel and uncontrollable stimulation...
Trauma and PTSD - an overlooked pathogenic pathway for premenstrual dysphoric disorder?H U Wittchen
Technical University of Dresden, Institute of Clinical Psychology and Psychotherapy, Dresden, Germany
Arch Womens Ment Health 6:293-7. 2003..A recent epidemiological analysis on premenstrual dysphoric disorder (PMDD) in the community revealed increased rates of DSM-IV posttraumatic stress disorder (PTSD) among women suffering from PMDD...
Prevalence of psychiatric disorders in an onset cohort of adults with type 1 diabetesFrank Petrak
Department for Psychosomatic Medicine and Psychotherapy, Johannes Gutenberg University Mainz, Untere Zahlbacherstrasse 8, D 55131 Mainz, Germany
Diabetes Metab Res Rev 19:216-22. 2003..The aim of our study was to determine if newly diagnosed adults with type 1 diabetes already have an elevated rate of psychiatric disorders at the beginning of their physical illness...
Generalized anxiety disorder: comorbidity, comparative biology and treatmentDavid J Nutt
School of Medical Sciences, University of Bristol, UK
Int J Neuropsychopharmacol 5:315-25. 2002..Finally, current pharmacological and non-pharmacological treatment options for GAD are reviewed, with particular attention being paid to published clinical-trial data...
Smoking increases the risk of panic: findings from a prospective community studyBarbara Isensee
Clinical Psychology and Epidemiology Unit, Max-Planck-Institute of Psychiatry, Munich, Germany
Arch Gen Psychiatry 60:692-700. 2003..However, we could not exclude the existence of a second, less frequent, reverse pathway of prior panic and secondary nicotine dependence...
The prevalence of treated and untreated mental disorders in five countriesRob V Bijl
Department of Crime Prevention and Sanctions, Research and Documentation Center, Ministry of Justice, The Netherlands
Health Aff (Millwood) 22:122-33. 2003..Undertreatment of serious cases is most pronounced among young poorly educated males. Outreach is needed to reduce barriers to care among serious cases and young people at risk of serious disorders...
Life events and changes in the course of depression in young adultsRobert H Friis
Department of Health Science, California State University, Long Beach, CA, USA
Eur Psychiatry 17:241-53. 2002..CONCLUSIONS: The association between life events and the course of depression appears to vary according to the outcome being examined, with different clusters of life events differentially predicting onset, improvement, and stability...
What predicts incident use of cannabis and progression to abuse and dependence? A 4-year prospective examination of risk factors in a community sample of adolescents and young adultsKirsten von Sydow
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstrasse 2, D 80804 Munich, Germany
Drug Alcohol Depend 68:49-64. 2002..To determine risk factors of incident onset of use, abuse and dependence of cannabis in a community sample of adolescents and young adults...
Test-retest reliability of self-reported age at onset of selected psychiatric diagnoses in general health careKatrin Barkow
Department of Psychiatry, University of Bonn, Germany
Acta Psychiatr Scand 106:117-25. 2002..CONCLUSION: Self-reported age at onset is reliable. Further research on factors associated with reliability should focus on interview conditions and subject parameters during interview...
Patterns and correlates of generalized anxiety disorder in community samplesRonald C Kessler
Department of Health Care Policy, Harvard Medical School, Boston, Mass 02115, USA
J Clin Psychiatry 63:4-10. 2002..Although generalized anxiety disorder (GAD) is at least twice as prevalent as panic disorder and is among the commonly occurring mental disorders, changing diagnostic criteria have hampered the cumulation of data on patterns and correlates...
Aims, design and methods of the Smoking and Nicotine Dependence Awareness and Screening (SNICAS) studyStephan Muehlig
Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Dresden, Germany
Int J Methods Psychiatr Res 12:208-28. 2003..This paper provides an overview of the design and methods of the study, informs about sampling and response rates, and examines whether the study sample could be considered representative of German primary care doctors...
Mixed anxiety-depression in a 1 year follow-up study: shift to other diagnoses or remission?Katrin Barkow
Department of Psychiatry, University of Bonn, Germany
J Affect Disord 79:235-9. 2004..However, a study examining the stability of this ICD-10-diagnosis is lacking. Our objective was to examine the 12 month outcome of MAD in comparison to the outcome of depression, anxiety, and comorbid depression and anxiety...
Broadening the definition of generalized anxiety disorder: effects on prevalence and associations with other disorders in the National Comorbidity Survey ReplicationAyelet Meron Ruscio
Department of Health Care Policy, Harvard Medical School, USA
J Anxiety Disord 21:662-76. 2007..Further research is needed to determine whether broadening the current diagnostic criteria results in a more valid characterization of GAD...
One-year mortality rates of patients receiving methadone and buprenorphine maintenance therapy: a nationally representative cohort study in 2694 patientsMichael Soyka
Psychiatric Hospital, University of Munich, Munich, Germany
J Clin Psychopharmacol 26:657-60. 2006..Taking into account the high comorbidity of opioid dependent patients and the severity of dependence, the mortality rate of approximately 1% confirms that maintenance treatment could be regarded as a fairly safe treatment...
Panic attack as a risk factor for severe psychopathologyRenee D Goodwin
Max Planck Institute of Psychiatry, Kraepelinstr. 2, 80804 Munich, Germany
Am J Psychiatry 161:2207-14. 2004..Investigation of key family, environmental, and individual factors associated with the onset of panic attacks, especially in youth, may be an important direction for future research...
Pathways into ecstasy use: the role of prior cannabis use and ecstasy availabilityPetra Zimmermann
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstrasse 2, 80804 Munich, Germany
Drug Alcohol Depend 79:331-41. 2005..To explore the role of cannabis use for the availability of ecstasy as a potential pathway to subsequent first ecstasy use...
