P E H Schwarz

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. ncbi request reprint Ethnic differences in C-peptide secretion but not in non-esterified fatty acid metabolism in pre-menopausal women with and without abdominal obesity
    Manja Reimann
    School for Physiology, Nutrition and Consumer Sciences, North West University Potchefstroom Campus, Potchefstroom, South Africa
    Diabetes Res Clin Pract 77:62-9. 2007
  2. ncbi request reprint [Prevention of type 2 diabetes in Germany. Ideas, evidence, implementation]
    Peter E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
    Med Klin (Munich) 101:730-6. 2006
  3. ncbi request reprint [Prevention of diabetes mellitus: the future of German diabetology]
    P E H Schwarz
    Medizinische Klinik III, Universitatsklinikum Carl Gustav Carus, der Technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
    Hamostaseologie 27:13-21. 2007
  4. ncbi request reprint Congress report from the American Diabetes Association 66th Annual Scientific Sessions in Washington, USA
    P E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Germany
    Exp Clin Endocrinol Diabetes 114:605-10. 2006
  5. ncbi request reprint Elevated fasting glucose levels predicts IGT and diabetes also in middle-age subjects
    Peter E H Schwarz
    Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Fetscherstrasse 74, Dresden, Germany
    Diabetes Res Clin Pract 77:148-50. 2007
  6. ncbi request reprint Diabetes prevention--from physiology to implementation
    P E H Schwarz
    Technical University of Dresden, Medical Faculty Carl Gustav Carus, Medical Clinic III, Department of Endocrinopathies and Metabolic Disease, Dresden, Germany
    Horm Metab Res 38:460-4. 2006
  7. ncbi request reprint Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population
    P E H Schwarz
    III Medical Clinic Department of Endocrinopathies and Metabolic Diseases, Dresden, Germany
    Horm Metab Res 38:447-51. 2006
  8. ncbi request reprint Hypoadiponectinemia is associated with progression toward type 2 diabetes and genetic variation in the ADIPOQ gene promoter
    Peter E H Schwarz
    Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Medical Clinic III, Building 46, Room 10, Fetscherstrasse 74, 01309, Dresden, Germany
    Diabetes Care 29:1645-50. 2006
  9. ncbi request reprint Report from the Congress of the American Diabetes Association (ADA): Orlando 2005 - 65th Annual Scientific Sessions in San Diego, CA, USA, June 10th-14th 2005
    P E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Germany
    Exp Clin Endocrinol Diabetes 113:475-9. 2005
  10. ncbi request reprint [Targeted diabetes prevention in high risk groups: pro]
    P Schwarz
    Bereich Endokrinopathien und Klinische Stoffwechselkrankheiten, Medizinische Fakultät Carl Gustav Carus der Technischen Universität Dresden
    Dtsch Med Wochenschr 130:1103. 2005

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Ethnic differences in C-peptide secretion but not in non-esterified fatty acid metabolism in pre-menopausal women with and without abdominal obesity
    Manja Reimann
    School for Physiology, Nutrition and Consumer Sciences, North West University Potchefstroom Campus, Potchefstroom, South Africa
    Diabetes Res Clin Pract 77:62-9. 2007
    ..This may be of importance for the development of hypertension in this population group...
  2. ncbi request reprint [Prevention of type 2 diabetes in Germany. Ideas, evidence, implementation]
    Peter E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
    Med Klin (Munich) 101:730-6. 2006
    ..This guideline also includes the structure of a national prevention program with a prevention manager having a central role in the concept and suggestions for evaluation and quality control...
  3. ncbi request reprint [Prevention of diabetes mellitus: the future of German diabetology]
    P E H Schwarz
    Medizinische Klinik III, Universitatsklinikum Carl Gustav Carus, der Technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
    Hamostaseologie 27:13-21. 2007
    ..This guideline also includes the structure of a national prevention program with a prevention manager having a central role in the concept and suggestions for evaluation and quality control...
  4. ncbi request reprint Congress report from the American Diabetes Association 66th Annual Scientific Sessions in Washington, USA
    P E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Germany
    Exp Clin Endocrinol Diabetes 114:605-10. 2006
  5. ncbi request reprint Elevated fasting glucose levels predicts IGT and diabetes also in middle-age subjects
    Peter E H Schwarz
    Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Fetscherstrasse 74, Dresden, Germany
    Diabetes Res Clin Pract 77:148-50. 2007
    ..We therefore conclude that elevated fasting glucose levels in the "IFG" category predict the development of IGT/diabetes in a middle-age population...
  6. ncbi request reprint Diabetes prevention--from physiology to implementation
    P E H Schwarz
    Technical University of Dresden, Medical Faculty Carl Gustav Carus, Medical Clinic III, Department of Endocrinopathies and Metabolic Disease, Dresden, Germany
    Horm Metab Res 38:460-4. 2006
    ..This process will be challenging and time consuming, requiring many partners but resulting in a profitable "health" investment...
  7. ncbi request reprint Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population
    P E H Schwarz
    III Medical Clinic Department of Endocrinopathies and Metabolic Diseases, Dresden, Germany
    Horm Metab Res 38:447-51. 2006
    ..006) after correction for BMI and age. Our observations suggest that diploid combinations of haplotype in the adiponectin gene promoter region contribute to the genetic risk of T2D in individuals from a German Caucasian population...
  8. ncbi request reprint Hypoadiponectinemia is associated with progression toward type 2 diabetes and genetic variation in the ADIPOQ gene promoter
    Peter E H Schwarz
    Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Medical Clinic III, Building 46, Room 10, Fetscherstrasse 74, 01309, Dresden, Germany
    Diabetes Care 29:1645-50. 2006
    ..The aim of the current study was to investigate whether ADIPOQ gene variants in the promoter region predict adiponectin levels and type 2 diabetes progression...
  9. ncbi request reprint Report from the Congress of the American Diabetes Association (ADA): Orlando 2005 - 65th Annual Scientific Sessions in San Diego, CA, USA, June 10th-14th 2005
    P E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Germany
    Exp Clin Endocrinol Diabetes 113:475-9. 2005
  10. ncbi request reprint [Targeted diabetes prevention in high risk groups: pro]
    P Schwarz
    Bereich Endokrinopathien und Klinische Stoffwechselkrankheiten, Medizinische Fakultät Carl Gustav Carus der Technischen Universität Dresden
    Dtsch Med Wochenschr 130:1103. 2005
  11. doi request reprint Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives
    P E H Schwarz
    Division of Endocrinology, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technical University Dresden, Dresden, Germany
    Pharmacogenomics J 9:42-8. 2009
    ..Thus, to examine diabetes risk, a more global approach including the design of population-specific experimental strategies should be used, which will be crucial in developing health education and policies in a global health programme...
  12. ncbi request reprint Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes
    A Bergmann
    Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S56-8. 2008
    ..But some other studies showed that, this association was not significant in Chinese and French . The aim of the current study was to examine whether the associations manifested in a German population with high risk of type 2 diabetes...
  13. doi request reprint A more simplified Finnish diabetes risk score for opportunistic screening of undiagnosed type 2 diabetes in a German population with a family history of the metabolic syndrome
    J Li
    Department of Medicine, Carl Gustav Carus, Technical University Dresden, Dresden, Germany
    Horm Metab Res 41:98-103. 2009
    ..The FINDRISC questionnaire can be used to identify undetected diabetes in a German population. The simplified version, the categorical-model, may be a useful alternative for identifying asymptomatic type 2 diabetes...
  14. ncbi request reprint The A98V single nucleotide polymorphism (SNP) in hepatic nuclear factor 1 alpha (HNF-1alpha) is associated with insulin sensitivity and beta-cell function
    A Bergmann
    Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:S50-5. 2008
    ..The aims of the study was to determine whether two single nucleotide polymorphisms (SNPs) ile27-to-leu and ala98-to-val in the HNF-1alpha gene associate with diabetes, insulin sensitivity as well as beta-cell function...
  15. ncbi request reprint Genetic variation of Neurogenin 3 is slightly associated with hyperproinsulinaemia and progression toward type 2 diabetes
    J Li
    Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:178-83. 2008
    ..The aim of the current study was to investigate the relevance of NGN3 variants for the clinical spectrum of diabetes development and disease progressions...
  16. doi request reprint Tools for predicting the risk of type 2 diabetes in daily practice
    P E H Schwarz
    Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany
    Horm Metab Res 41:86-97. 2009
    ..We conclude that the FINDRISC tool is currently the best available tool for use in clinical practice in Caucasian populations, but modifications may be required if applied to other ethnic groups...
  17. ncbi request reprint Circulating very-low-density lipoprotein from subjects with impaired glucose tolerance accelerates adrenocortical cortisol and aldosterone synthesis
    S Saha
    Department of Internal Medicine 3, Carl Gustav Carus Medical School, Technical University of Dresden, Dresden, Germany
    Horm Metab Res 45:169-72. 2013
    ..In summary, in vivo modified VLDL are able to promote prediabetic hormonal dysregulation by modulating adrenocortical steroidogenesis via Jak-2-ERK dependent pathway...
  18. ncbi request reprint The health status of Russian-speaking immigrants in Germany
    S Tselmin
    Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Horm Metab Res 39:858-61. 2007
    ..Nevertheless relevant data concerning migration-related public health care are very scare...
  19. ncbi request reprint A simplified Finnish diabetes risk score to predict type 2 diabetes risk and disease evolution in a German population
    A Bergmann
    Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
    Horm Metab Res 39:677-82. 2007
    ..We aimed to evaluate its performance to predict diabetes in a German population and to compare its predictive and detective ability in the same population...
  20. ncbi request reprint Insulin resistance -- the role of ethnicity: evidence from Caucasian and African cohorts
    M Reimann
    Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
    Horm Metab Res 39:853-7. 2007
    ..These factors may be influenced or modified by a central theme: visceral obesity. This mini review will elaborate on these issues illustrated by observations from Caucasian and African cohorts...
  21. ncbi request reprint An update on preventive and regenerative therapies in diabetes mellitus
    M Reimann
    Department of Internal Medicine III, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
    Pharmacol Ther 121:317-31. 2009
    ..Lastly, important efforts to halt disease progression with emphasis on beta-cell regeneration are presented...
  22. ncbi request reprint The Metabolic Syndrome - a global challenge for prevention
    P E H Schwarz
    Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
    Horm Metab Res 39:777-80. 2007
    ..A global health strategy has to take into account political, epidemiological, environmental, infrastructural and genetic aspects. The Metabolic Syndrome is not a mystery - it is a clinical paradigm and global challenge...
  23. doi request reprint The European perspective of type 2 diabetes prevention: diabetes in Europe--prevention using lifestyle, physical activity and nutritional intervention (DE-PLAN) project
    P E H Schwarz
    Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
    Exp Clin Endocrinol Diabetes 116:167-72. 2008
    ..The DE-PLAN ("Diabetes in Europe - Prevention using Lifestyle, Physical Activity and Nutritional intervention") project, led by the University of Helsinki is currently addressing this major public health concern in Europe...
  24. ncbi request reprint The importance and effect of dietary fiber in diabetes prevention with particular consideration of whole grain products
    K Kaline
    Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
    Horm Metab Res 39:687-93. 2007
    ..A high intake of fruits and vegetables as well as pulses also exerts health-promoting properties. A high-fiber diet also plays an important role in the prevention of obesity and coronary heart diseases...
  25. ncbi request reprint High prevalence of dyslipidemia in the Dresden Jewish population
    S Tselmin
    Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
    Horm Metab Res 39:700-1. 2007
  26. ncbi request reprint Mutations and intronic variants in the HNF-1 beta gene in a group of German and Czech Caucasians with type 2 diabetes mellitus and progressive diabetic nephropathy
    T Selisko
    Department of Internal Medicine III, University Clinic Carl Gustav Carus of the Technical University Dresden, Germany
    Exp Clin Endocrinol Diabetes 110:145-7. 2002
    ..The results confirm that the genetic variations in the HNF-1 beta gene would be a very uncommon cause of progressive nephropathy in patients with type 2 diabetes mellitus...
  27. ncbi request reprint Lipidomic profiling before and after Roux-en-Y gastric bypass in obese patients with diabetes
    J Graessler
    Department of Medicine III, Carl Gustav Carus Medical School, TU Dresden, Dresden, Germany
    Pharmacogenomics J 14:201-7. 2014
    ..These striking changes in the human plasma lipidome may explain acute, weight independent and long-term effects of RYGB on the cardiovascular system, mental status and immune regulation. ..
  28. ncbi request reprint Assessment of small C-fiber status for screening of oxidative stress in patients at risk of diabetes
    E Parfentyeva
    University Clinic Carl Gustav Carus at the Technical University Dresden, Dresden, Germany
    Horm Metab Res 46:360-4. 2014
    ..Based on these results it may be concluded that Ezscan could be a useful screening tool in daily practice to assess alterations in oxidative stress parameters in individuals at risk of developing diabetes. ..
  29. doi request reprint Single whole blood dextran sulfate adsorption favorably affects systemic oxidative balance in lipoprotein apheresis patients
    S Kopprasch
    Department of Internal Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany
    Atheroscler Suppl 14:157-60. 2013
    ..The acute changes of circulating oxidative stress parameters were compared in 16 patients undergoing two different apheresis techniques: plasma lipidfiltration (LF) or whole blood dextran sulfate adsorption (DSA)...
  30. ncbi request reprint The European perspective of diabetes prevention
    P E H Schwarz
    Department of Prevention on Care of Type 2 Diabetes, Clinic of Internal Medicine III, Medical Faculty Carl Gustav Carus, Technical University Dresden, Dresden, Germany
    Horm Metab Res 40:511-4. 2008
    ..The DPF is taking immediate action to co-ordinate and improve the information flow between all relevant stakeholders to enable more effective communication, so helping to improve the ability to prevent type 2 diabetes in Europe...
  31. ncbi request reprint The European perspective of diabetes prevention: the need for individualization of diabetes prevention
    G Muller
    Technical University, Dresden, Germany
    J Endocrinol Invest 36:352-7. 2013
    ..In the current discussion about the management of health care resources it is important to have a strategic vision about a realistic future of innovative chronic care management...
  32. ncbi request reprint Prevention of type 2 diabetes--lessons we have learnt for implementation
    P E H Schwarz
    IIIo Medical Clinic, Carl Gustav Carus Medical School, Dresden University of Technology, Dresden, Germany
    Horm Metab Res 39:636-41. 2007
    ..We focus on the development of a structured prevention management program which will enable implementation of diabetes prevention into clinical practice...
  33. ncbi request reprint Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses
    Takafumi Tsuchiya
    Departments of Medicine and Human Genetics, The University of Chicago, 5841 S Maryland Ave, MC1027, Chicago, IL 60637, USA
    Mol Genet Metab 89:174-84. 2006
    ..68 (1.33-2.11), P=0.00001). The pooled and meta-analyses as well as the linkage disequilibrium and haplotype diversity studies suggest a role for genetic variation in CAPN10 affecting risk of T2D in Europeans...
  34. ncbi request reprint An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes: response to Schulze et al
    Peter E H Schwarz
    Diabetes Care 30:e87; author reply e88. 2007
  35. pmc Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility
    Michael N Weedon
    Am J Hum Genet 73:1208-12. 2003
  36. pmc Development of a diabetes prevention management program for clinical practice
    Peter E H Schwarz
    Department of Internal Medicine, Carl Gustav Carus Medical School, Dresden University of Technology, Germany
    Public Health Rep 122:258-63. 2007
  37. doi request reprint [Prevention in occupational health care--a societal challenge]
    Peter E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Dresden
    Med Klin (Munich) 103:210-6. 2008
    ..This process will be challenging and must be sustainable requiring many partners but resulting in a profitable chance for occupational health care...
  38. ncbi request reprint [Prevention of type 2 diabetes in Germany--a challenge for health professionals]
    Peter E H Schwarz
    Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden
    Med Monatsschr Pharm 30:289-96. 2007
    ..This process will be challenging and time consuming, requiring many partners but resulting in a profitable "health" investment...
  39. ncbi request reprint How should the clinician most effectively prevent type 2 diabetes in the obese person at high risk?
    Peter E H Schwarz
    Department of Public Health, University of Helsinki, Mannerheimintie 172, 00300 Helsinki, Finland
    Curr Diab Rep 7:353-62. 2007
    ..The implementation of managed prevention concepts will realistically help to improve the ability to prevent T2D in the public health framework...
  40. ncbi request reprint Evaluation of a diabetes management system based on practice guidelines, integrated care, and continuous quality management in a Federal State of Germany: a population-based approach to health care research
    Ulrike Rothe
    Institute for Medical Informatics and Biometrics, Medical Faculty Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Diabetes Care 31:863-8. 2008
    ..The SDMP was implemented into diabetes contracts between health insurance providers, general practitioners (GPs), and diabetes specialized practitioners (DSPs) unified in the Saxon association of Statutory Health Insurance Physicians...
  41. ncbi request reprint Protective effect against type 2 diabetes mellitus identified within the ACDC gene in a black South African diabetic cohort
    Antonel Olckers
    Centre for Genome Research, North West University Potchefstroom Campus, Persequor Park, Pretoria, South Africa
    Metabolism 56:587-92. 2007
    ..This investigation therefore underscores the genetic heterogeneity at T2D susceptibility loci within the black South African population...
  42. ncbi request reprint Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome
    David A Ehrmann
    Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
    J Clin Endocrinol Metab 87:1669-73. 2002
    ..In addition to its association with insulin levels in African-Americans, the 112/121-haplotype combination was associated with an approximate 2-fold increase in risk of PCOS in both African-Americans and whites...
  43. ncbi request reprint The European perspective on diabetes prevention: development and Implementation of A European Guideline and training standards for diabetes prevention (IMAGE)
    Peter E H Schwarz
    Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany
    Diab Vasc Dis Res 4:353-7. 2007
    ....
  44. ncbi request reprint Differences and similarities regarding adiponectin investigated in African and Caucasian women
    Aletta E Schutte
    School for Physiology, Nutrition and Consumer Sciences, North West University Potchefstroom Campus, Private Bag X6001, Potchefstroom 2520, South Africa
    Eur J Endocrinol 157:181-8. 2007
    ..A second objective was to determine which components of the metabolic syndrome are more closely related to adiponectinemia in both groups...
  45. ncbi request reprint An inverse association between calcium and adiposity in women with high fat and calcium intakes
    H Salome Kruger
    School of Physiology, Nutrition and Consumer Science, North West University, Potchefstroom 2520, South Africa
    Ethn Dis 17:6-13. 2007
    ..To assess the association between calcium intake and body composition in African Black and White women...
  46. ncbi request reprint Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects
    Naoko Iwasaki
    Diabetes Center, Tokyo Women s Medical University, Tokyo, Japan
    Diabetes 52:209-13. 2003
    ..Thus, our results may replicate findings in other studies. They may also indicate new regions of the genome that are involved in the regulation of blood glucose levels or body weight...
  47. ncbi request reprint Validation of a simple clinical diabetes prediction model in a middle-aged, white, German population
    Jiang Li
    Arch Intern Med 167:2528-9. 2007