Christoph Schindler

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. doi request reprint Characterization of local vascular effects of the nitric oxide inhibitor NG-monomethyl-L-arginine on dorsal hand veins
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Fiedlerstrasse 27, D 01307 Dresden, Germany
    J Clin Pharmacol 52:859-69. 2012
  2. doi request reprint [Benefits and risks of current pharmacotherapy in the treatment of type 2 diabetes]
    C Schindler
    Institut fur Klinische Pharmakologie, Medizinische Fakultat, TU Dresden
    Internist (Berl) 53:478, 480-5, 487. 2012
  3. ncbi request reprint Cardiovascular risk in obese hypertensive patients taking various antihypertensive drugs
    Christoph Schindler
    Institute of Clinical Pharmacology, Technical University, Dresden, Germany
    Clin Drug Investig 27:707-17. 2007
  4. pmc Role of the vasodilator peptide angiotensin-(1-7) in cardiovascular drug therapy
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
    Vasc Health Risk Manag 3:125-37. 2007
  5. ncbi request reprint Asymptomatic statin-induced rhabdomyolysis after long-term therapy with the hydrophilic drug pravastatin
    Christoph Schindler
    Institute of Clinical Pharmacology, Faculty of Medicine, Technical University of Dresden, Dresden, Germany
    Clin Ther 29:172-6. 2007
  6. ncbi request reprint Comparison of inhibitory effects of irbesartan and atorvastatin treatment on the renin angiotensin system (RAS) in veins: a randomized double-blind crossover trial in healthy subjects
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty of the University of Technology, Fiedlerstrasse 27, D 01307 Dresden, Germany
    J Clin Pharmacol 47:112-20. 2007
  7. ncbi request reprint Comparison of selective AT1-receptor blockade versus ACE inhibition for restenosis prophylaxis in patients with peripheral occlusive arterial disease after stent angioplasty: a randomized, controlled, proof-of-concept study
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Germany
    Angiology 58:710-6. 2007
  8. ncbi request reprint Characterization of vascular reactivity in dorsal hand veins after oral rosiglitazone treatment in healthy subjects
    C Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Dresden, Germany
    Int J Clin Pharmacol Ther 46:30-9. 2008
  9. doi request reprint Managing hypertension among nursing-home residents and community-dwelling elderly in Germany: a comparative pharmacoepidemiological study
    Sophie Lochner
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Fiedlerstrasse 27, D 01307 Dresden, Germany
    Eur J Clin Pharmacol 68:867-75. 2012
  10. doi request reprint Current pharmacotherapeutic concepts for the treatment of obesity in adults
    Evgeny Idelevich
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
    Ther Adv Cardiovasc Dis 3:75-90. 2009

Detail Information

Publications26

  1. doi request reprint Characterization of local vascular effects of the nitric oxide inhibitor NG-monomethyl-L-arginine on dorsal hand veins
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Fiedlerstrasse 27, D 01307 Dresden, Germany
    J Clin Pharmacol 52:859-69. 2012
    ..Venous reactivity to L-NMMA resulting in a phenotype as R or NR is most likely genetically predetermined, which requires further study...
  2. doi request reprint [Benefits and risks of current pharmacotherapy in the treatment of type 2 diabetes]
    C Schindler
    Institut fur Klinische Pharmakologie, Medizinische Fakultat, TU Dresden
    Internist (Berl) 53:478, 480-5, 487. 2012
    ..Furthermore, new and still experimental approaches for the treatment of T2DM, such as bardoxolone, salsalate and anakinra will be briefly reviewed...
  3. ncbi request reprint Cardiovascular risk in obese hypertensive patients taking various antihypertensive drugs
    Christoph Schindler
    Institute of Clinical Pharmacology, Technical University, Dresden, Germany
    Clin Drug Investig 27:707-17. 2007
    ..We aimed to assess the risk factor profiles of primary-care patients with obesity and hypertension in order to estimate their fatal CV risk in total and according to use of various antihypertensive drugs...
  4. pmc Role of the vasodilator peptide angiotensin-(1-7) in cardiovascular drug therapy
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
    Vasc Health Risk Manag 3:125-37. 2007
    ..In addition, the potential therapeutic impact of currently available RAS blocking agents (ACE-1 and ARBs) and new agents still under development (renin-inhibitors) on the RAS-effector peptides is highlighted...
  5. ncbi request reprint Asymptomatic statin-induced rhabdomyolysis after long-term therapy with the hydrophilic drug pravastatin
    Christoph Schindler
    Institute of Clinical Pharmacology, Faculty of Medicine, Technical University of Dresden, Dresden, Germany
    Clin Ther 29:172-6. 2007
    ..The patient was diagnosed with acute rhabdomyolysis; a score of 6 on the Naranjo adverse drug reaction probability scale indicated that pravastatin was the probable cause...
  6. ncbi request reprint Comparison of inhibitory effects of irbesartan and atorvastatin treatment on the renin angiotensin system (RAS) in veins: a randomized double-blind crossover trial in healthy subjects
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty of the University of Technology, Fiedlerstrasse 27, D 01307 Dresden, Germany
    J Clin Pharmacol 47:112-20. 2007
    ..The data indicate that atorvastatin does not inhibit Ang II-induced venoconstriction in vivo and point toward a supportive role of Ang-(1-7) in contributing to the antihypertensive and beneficial vascular effects of irbesartan...
  7. ncbi request reprint Comparison of selective AT1-receptor blockade versus ACE inhibition for restenosis prophylaxis in patients with peripheral occlusive arterial disease after stent angioplasty: a randomized, controlled, proof-of-concept study
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Germany
    Angiology 58:710-6. 2007
    ..Further prospective studies in patients are required to confirm these results...
  8. ncbi request reprint Characterization of vascular reactivity in dorsal hand veins after oral rosiglitazone treatment in healthy subjects
    C Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Dresden, Germany
    Int J Clin Pharmacol Ther 46:30-9. 2008
    ..The present study was undertaken to investigate whether rosiglitazone modulates vascular responsiveness to different vasoactive agents and exerts renin-angiotensin-system (RAS)-inhibiting properties in healthy subjects in vivo...
  9. doi request reprint Managing hypertension among nursing-home residents and community-dwelling elderly in Germany: a comparative pharmacoepidemiological study
    Sophie Lochner
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Fiedlerstrasse 27, D 01307 Dresden, Germany
    Eur J Clin Pharmacol 68:867-75. 2012
    ..The purpose of this study was to investigate the adequacy of hypertension management in hypertensive elderly living in long-term-care facilities compared with home-living elderly...
  10. doi request reprint Current pharmacotherapeutic concepts for the treatment of obesity in adults
    Evgeny Idelevich
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany
    Ther Adv Cardiovasc Dis 3:75-90. 2009
    ..This review summarizes current pharmacotherapeutic concepts for the treatment of obesity in adults focusing on efficacy and safety of anti-obesity drugs...
  11. ncbi request reprint The metabolic syndrome as an endocrine disease: is there an effective pharmacotherapeutic strategy optimally targeting the pathogenesis?
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Fiedlerstrasse 27, 01307 Dresden, Germany christoph schindler tu dresden de
    Ther Adv Cardiovasc Dis 1:7-26. 2007
    ....
  12. ncbi request reprint Mechanisms of beta-adrenergic receptor-mediated venodilation in humans
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Dresden University of Technology, Germany
    Clin Pharmacol Ther 75:49-59. 2004
    ..This study was designed to elucidate the underlying mechanisms of isoproterenol (INN, isoprenaline)-induced venodilation by investigation of dorsal hand vein responses...
  13. ncbi request reprint First patient-centered drug information service in Germany--a descriptive study
    Ulf Maywald
    Institute of Clinical Pharmacology, Dresden University of Technology, Fiedlerstrasse 27, D 01307 Dresden, Germany
    Ann Pharmacother 38:2154-9. 2004
    ..The majority of patients have unmet drug information needs, and patients' knowledge of their own treatment is often poor. This is a major obstacle to a more patient-centered healthcare system...
  14. ncbi request reprint [Prevention of cardiovascular disease by blocking the endocannabinoid system]
    Peter Bramlage
    Institut fur Klinische Pharmakologie, Medizinische Fakultat, TU Dresden, Dresden
    Herz 32:560-7. 2007
    ....
  15. ncbi request reprint [Recent examples for drug (developments) in primary, secondary and tertiary prevention]
    P Bramlage
    Institut fur Klinische Pharmakologie, Medizinische Fakultät Carl Gustav Carus, Technische Universitat Dresden, Fiedlerstrasse 27, 01307 Dresden, Deutschland
    Dtsch Med Wochenschr 132:2212-6. 2007
    ....
  16. ncbi request reprint Reproducibility of dorsal hand vein responses to phenylephrine and prostaglandin F2 alpha using the dorsal hand vein compliance method
    C Schindler
    Institute of Clinical Pharmacology, Medical Faculty of the University of Technology Dresden, Fiedlerstrasse 27, D 01307 Dresden, Germany
    J Clin Pharmacol 43:228-36. 2003
    ..However, in such studies, phenylephrine appears to be a more reliable tool than PGF2 alpha...
  17. ncbi request reprint Smart textiles: a new drug delivery system for symptomatic treatment of a common cold
    F Wienforth
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Fiedlerstr 27, 01307 Dresden, Germany
    J Clin Pharmacol 47:653-9. 2007
    ..Slower liberation properties and a more convenient skin sensation in comparison to available pharmaceutical forms may provide advantages for the applicability in both children and adults...
  18. ncbi request reprint Pattern of prescriptions issued by nursing home-based physicians versus office-based physicians for frail elderly patients in German nursing homes
    David Pittrow
    Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Fiedlerstr 27, D 01307 Dresden, Germany
    Pharmacoepidemiol Drug Saf 12:595-9. 2003
    ....
  19. ncbi request reprint Severe temporomandibular dysfunction and joint destruction after intra-articular injection of triamcinolone
    C Schindler
    Institute of Clinical Pharmacology, Medical Faculty, University of Technology, Dresden, Germany
    J Oral Pathol Med 34:184-6. 2005
    ..Steroid injections into joints are frequently used to control symptomatic pain. Risks associated with intra-articular steroid injections are not well documented...
  20. ncbi request reprint [Gastrointestinal bleeding during low dose acetylsalicylic acid. Is Godamed-100 TAH an alternative to conventional ASS preparations?]
    U Maywald
    Institut fur Klinische Pharmakologie, Medizinische Fakultät der TU Dresden, Dresden
    Dtsch Med Wochenschr 130:1026-7. 2005
  21. ncbi request reprint [Drug information for patients -- unmet needs, evaluation and influence on the compliance]
    U Maywald
    Institut fur Klinische Pharmakologie, Technische Universitat Dresden
    Dtsch Med Wochenschr 130:1485-90. 2005
    ..We report the three-year experiences with the first drug information service for patients in Germany. We evaluate the impact of the advice on outcomes, patient sovereignty and Compliance...
  22. doi request reprint Evaluation of a program of integrated care to reduce recurrent osteoporotic fractures
    Lisa Goltz
    Institute of Clinical Pharmacology, Medical Faculty, Technical University Dresden, Fiedlerstrasse 27, D 01307, Dresden, Germany
    Pharmacoepidemiol Drug Saf 22:263-70. 2013
    ..To evaluate the outcomes of patients participating in a program of integrated care for osteoporosis in terms of medication supply, fracture incidence and expenses...
  23. ncbi request reprint Reoccurrence of levofloxacin-induced tendinitis by phenoxymethylpenicillin therapy after 6 months: a rare complication of fluoroquinolone therapy?
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty of the Dresden University of Technology, Dresden, Germany
    Chemotherapy 49:90-1. 2003
  24. ncbi request reprint Prescriptions of systemic antibiotics for children in Germany aged between 0 and 6 years
    Christoph Schindler
    Institute of Clinical Pharmacology, Medical Faculty, Technical University, Fiedlerstrasse 27, D 01307 Dresden, Germany
    Pharmacoepidemiol Drug Saf 12:113-20. 2003
    ..As such treatment may be associated with the development of bacterial resistance, improved guidelines for antibiotic treatment should be drawn up and enforced...
  25. ncbi request reprint The effects of bupropion on heart rate variability in healthy volunteers
    Martin Siepmann
    J Clin Psychopharmacol 25:283-5. 2005
  26. ncbi request reprint The effects of bupropion on cognitive functions in healthy subjects
    Martin Siepmann
    Psychopharmacology (Berl) 182:597-8. 2005