Guido Melzer

Summary

Affiliation: Technical University of Braunschweig
Country: Germany

Publications

  1. pmc Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstr 17, 38106 Braunschweig, Germany
    BMC Syst Biol 3:120. 2009
  2. doi request reprint Characterization and control of fungal morphology for improved production performance in biotechnology
    Rainer Krull
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Germany
    J Biotechnol 163:112-23. 2013
  3. doi request reprint Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production
    Habib Driouch
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstra├če 17, 38106 Braunschweig, Germany
    Metab Eng 14:47-58. 2012
  4. ncbi request reprint Metabolic flux analysis using stoichiometric models for Aspergillus niger: comparison under glucoamylase-producing and non-producing conditions
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstr 17, 38106 Braunschweig, Germany
    J Biotechnol 132:405-17. 2007
  5. doi request reprint Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstrasse 17, 38106 Braunschweig, Germany
    J Ind Microbiol Biotechnol 35:485-93. 2008

Detail Information

Publications5

  1. pmc Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstr 17, 38106 Braunschweig, Germany
    BMC Syst Biol 3:120. 2009
    ..Efficient in silico methods for simultaneous genome-scale identification of targets to be amplified or deleted are still lacking...
  2. doi request reprint Characterization and control of fungal morphology for improved production performance in biotechnology
    Rainer Krull
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Germany
    J Biotechnol 163:112-23. 2013
    ..Based on the novel insights available from such studies, more recent studies have been aimed at the precise control of morphology, i.e., morphology engineering, to produce superior bio-processes with filamentous fungi...
  3. doi request reprint Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production
    Habib Driouch
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstra├če 17, 38106 Braunschweig, Germany
    Metab Eng 14:47-58. 2012
    ..niger. Selected fluxes, however, changed contrary to the predicted optimum and thus revealed novel targets-including reactions linked to NADPH metabolism and gluconate formation...
  4. ncbi request reprint Metabolic flux analysis using stoichiometric models for Aspergillus niger: comparison under glucoamylase-producing and non-producing conditions
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstr 17, 38106 Braunschweig, Germany
    J Biotechnol 132:405-17. 2007
    ..5, 56% at pH 3.7, respectively). Summarizing, the flux through the PPP under glucoamylase producing conditions was 30-90% higher than for non-producing conditions...
  5. doi request reprint Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina
    Guido Melzer
    Institute of Biochemical Engineering, Technische Universitat Braunschweig, Gaussstrasse 17, 38106 Braunschweig, Germany
    J Ind Microbiol Biotechnol 35:485-93. 2008
    ..4 times higher when using R-pNSO. A protein purification strategy leading to a 47-fold increase in specific activity (940 U/mgProtein) was developed as a first step to investigate molecular and structural characteristics of the EH...