Clemens Kirschbaum

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. doi request reprint The role of the serotonin transporter polymorphism for the endocrine stress response in newborns
    Anett Mueller
    Department of Psychology, Technische Universitaet Dresden, Zellescher Weg 17, 01062 Dresden, Germany
    Psychoneuroendocrinology 35:289-96. 2010
  2. doi request reprint Hair as a retrospective calendar of cortisol production-Increased cortisol incorporation into hair in the third trimester of pregnancy
    Clemens Kirschbaum
    Department of Psychology, Technical University of Dresden, 01062 Dresden, Germany
    Psychoneuroendocrinology 34:32-7. 2009
  3. doi request reprint Better not to deal with two tasks at the same time when stressed? Acute psychosocial stress reduces task shielding in dual-task performance
    Franziska Plessow
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany
    Cogn Affect Behav Neurosci 12:557-70. 2012
  4. doi request reprint Children with high-functioning autism show a normal cortisol awakening response (CAR)
    Katharina Zinke
    Department of Psychology, Technical University Dresden, D 01062 Dresden, Germany
    Psychoneuroendocrinology 35:1578-82. 2010
  5. doi request reprint Salivary alpha-amylase stress reactivity across different age groups
    Jana Strahler
    Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Psychophysiology 47:587-95. 2010
  6. doi request reprint Comparison of salivary cortisol as measured by different immunoassays and tandem mass spectrometry
    Robert Miller
    Department of Psychology, Technische Universitat Dresden, Germany
    Psychoneuroendocrinology 38:50-7. 2013
  7. doi request reprint Cortisol in hair, body mass index and stress-related measures
    Tobias Stalder
    Technical University of Dresden, Department of Psychology, Germany
    Biol Psychol 90:218-23. 2012
  8. doi request reprint Introducing a novel method to assess cumulative steroid concentrations: increased hair cortisol concentrations over 6 months in medicated patients with depression
    Lucia Dettenborn
    Department of Psychology, Technical University of Dresden, Dresden, Germany
    Stress 15:348-53. 2012
  9. doi request reprint Cortisol in hair and the metabolic syndrome
    Tobias Stalder
    Technische Universitat Dresden, Department of Psychology, Andreas Schubert Bau, Zellescher Weg 19, 01069 Dresden, Germany
    J Clin Endocrinol Metab 98:2573-80. 2013
  10. doi request reprint Intraindividual stability of hair cortisol concentrations
    Tobias Stalder
    Technische Universitat Dresden, Department of Psychology, 01062 Dresden, Germany
    Psychoneuroendocrinology 37:602-10. 2012

Detail Information

Publications48

  1. doi request reprint The role of the serotonin transporter polymorphism for the endocrine stress response in newborns
    Anett Mueller
    Department of Psychology, Technische Universitaet Dresden, Zellescher Weg 17, 01062 Dresden, Germany
    Psychoneuroendocrinology 35:289-96. 2010
    ..In this sample of newborn babies, the 5-HTTLPR genotype affected the HPA stress response to painful stimulation irrespective of additional influence of pre- or perinatal environmental factors we measured...
  2. doi request reprint Hair as a retrospective calendar of cortisol production-Increased cortisol incorporation into hair in the third trimester of pregnancy
    Clemens Kirschbaum
    Department of Psychology, Technical University of Dresden, 01062 Dresden, Germany
    Psychoneuroendocrinology 34:32-7. 2009
    ..Due to a rapid decline of cortisol levels in human adult hair, a retrospective calendar of cortisol exposure may be limited to the past six months...
  3. doi request reprint Better not to deal with two tasks at the same time when stressed? Acute psychosocial stress reduces task shielding in dual-task performance
    Franziska Plessow
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany
    Cogn Affect Behav Neurosci 12:557-70. 2012
    ....
  4. doi request reprint Children with high-functioning autism show a normal cortisol awakening response (CAR)
    Katharina Zinke
    Department of Psychology, Technical University Dresden, D 01062 Dresden, Germany
    Psychoneuroendocrinology 35:1578-82. 2010
    ....
  5. doi request reprint Salivary alpha-amylase stress reactivity across different age groups
    Jana Strahler
    Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Psychophysiology 47:587-95. 2010
    ..No associations between the parameters were found. These results implicate sAA as an alternative or additional sympathetic stress marker throughout the life span, with marked and rapid stress responsiveness in three relevant age groups...
  6. doi request reprint Comparison of salivary cortisol as measured by different immunoassays and tandem mass spectrometry
    Robert Miller
    Department of Psychology, Technische Universitat Dresden, Germany
    Psychoneuroendocrinology 38:50-7. 2013
    ..Finally guidelines for converting cortisol concentrations being obtained by these immunoassays into comparable reference values are proposed by providing conversion functions, a conversion table, and an online conversion tool...
  7. doi request reprint Cortisol in hair, body mass index and stress-related measures
    Tobias Stalder
    Technical University of Dresden, Department of Psychology, Germany
    Biol Psychol 90:218-23. 2012
    ..29, p=.03) but not with other stress-related measures...
  8. doi request reprint Introducing a novel method to assess cumulative steroid concentrations: increased hair cortisol concentrations over 6 months in medicated patients with depression
    Lucia Dettenborn
    Department of Psychology, Technical University of Dresden, Dresden, Germany
    Stress 15:348-53. 2012
    ....
  9. doi request reprint Cortisol in hair and the metabolic syndrome
    Tobias Stalder
    Technische Universitat Dresden, Department of Psychology, Andreas Schubert Bau, Zellescher Weg 19, 01069 Dresden, Germany
    J Clin Endocrinol Metab 98:2573-80. 2013
    ..This issue can be addressed by using hair cortisol analysis, which for the first time allows the assessment of long-term integrated hormone levels...
  10. doi request reprint Intraindividual stability of hair cortisol concentrations
    Tobias Stalder
    Technische Universitat Dresden, Department of Psychology, 01062 Dresden, Germany
    Psychoneuroendocrinology 37:602-10. 2012
    ....
  11. doi request reprint Association of blood pressure and antihypertensive drugs with diurnal alpha-amylase activity
    Jana Strahler
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany Department of Psychology, Philipps Universitat Marburg, 35032 Marburg, Germany
    Int J Psychophysiol 81:31-7. 2011
    ..Findings highlight the usefulness of sAA as an index of autonomic imbalance in disease, and indicate sAA as a promising candidate to non-invasively study therapeutic treatment effects...
  12. doi request reprint Human hypothalamus-pituitary-adrenal axis responses to acute psychosocial stress in laboratory settings
    Paul Foley
    Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Neurosci Biobehav Rev 35:91-6. 2010
    ..Characterization of the roles and interactions of these factors in generating a dysregulation of the neuroendocrine responses to acute psychosocial stress await longitudinal studies...
  13. doi request reprint The social dimension of stress reactivity: acute stress increases prosocial behavior in humans
    Bernadette von Dawans
    Department of Psychology, Laboratory for Biological and Personality Psychology, University of Freiburg, Germany
    Psychol Sci 23:651-60. 2012
    ..These results show that stress triggers social approach behavior, which operates as a potent stress-buffering strategy in humans, thereby providing evidence for the tend-and-befriend hypothesis...
  14. doi request reprint Elevated hair cortisol concentrations in endurance athletes
    Nadine Skoluda
    Department of Psychology, Technical University of Dresden, Dresden, Germany
    Psychoneuroendocrinology 37:611-7. 2012
    ..These findings may have important implications with regard to somatic and mental health of athletes which should be investigated in future research...
  15. doi request reprint Within and between session changes in subjective and neuroendocrine stress parameters during magnetic resonance imaging: A controlled scanner training study
    Ulrike Lueken
    Department of Psychology, Institute of Clinical Psychology and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Psychoneuroendocrinology 37:1299-308. 2012
    ..If replicated, present findings should be considered by researchers employing repeated measurement designs where subjects are exposed to a scanner more than once...
  16. doi request reprint Use of hair cortisol analysis to detect hypercortisolism during active drinking phases in alcohol-dependent individuals
    Tobias Stalder
    Technical University of Dresden, Department of Psychology, 01062 Dresden, Germany
    Biol Psychol 85:357-60. 2010
    ..The current hair cortisol findings closely mirror results of previous research using well-established measures of systemic cortisol secretion and thus provide further validation of this novel method...
  17. doi request reprint Aging diurnal rhythms and chronic stress: Distinct alteration of diurnal rhythmicity of salivary alpha-amylase and cortisol
    Jana Strahler
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany
    Biol Psychol 84:248-56. 2010
    ..Overall, our study does not support the AL hypothesis, but rather highlights the importance of regular physical activity and social environment in promoting health...
  18. doi request reprint The cortisol awakening response (CAR): facts and future directions
    Eva Fries
    Technische Universitat Dresden, Faculty of Science, Department of Psychology, Dresden, Germany
    Int J Psychophysiol 72:67-73. 2009
    ..The present paper reviews the current knowledge on the neural regulation of the CAR and factors influencing this phenomenon and considerations are addressed concerning the exact function of the CAR...
  19. doi request reprint The cortisol awakening response in toddlers and young children
    Damaris Bäumler
    Technische Universitat Dresden, Department of Psychology, Dresden, Germany
    Psychoneuroendocrinology 38:2485-92. 2013
    ..17, p=.04). Overall, the current findings strongly suggest that, contrary to previous propositions, the CAR is maintained consistently throughout toddler- and childhood...
  20. doi request reprint The cortisol awakening response in infants: ontogeny and associations with development-related variables
    Tobias Stalder
    Technische Universitat Dresden, Department of Psychology, Dresden, Germany
    Psychoneuroendocrinology 38:552-9. 2013
    ..The data also suggest that post-awakening cortisol secretion may undergo considerable changes during the first year of life associated with different aspects of infant development...
  21. doi request reprint Lower stress system activity and higher peripheral inflammation in competitive ballroom dancers
    Christiane Berndt
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany
    Biol Psychol 91:357-64. 2012
    ..Therefore, competitive ballroom dancing represents a chronic stressor that can lead to important functional consequences. It remains to be investigated whether these alterations are causally related to health...
  22. doi request reprint The stressed prefrontal cortex and goal-directed behaviour: acute psychosocial stress impairs the flexible implementation of task goals
    Franziska Plessow
    Department of Psychology, Technische Universitat Dresden, 01062 Dresden, Germany
    Exp Brain Res 216:397-408. 2012
    ..These results indicate that acute psychosocial stress impairs cognitive control processes of flexible task-goal implementation essential for voluntary goal-directed behaviour...
  23. doi request reprint Increased cortisol concentrations in hair of severely traumatized Ugandan individuals with PTSD
    Susann Steudte
    Department of Psychology, Technical University of Dresden, Dresden, Germany
    Psychoneuroendocrinology 36:1193-200. 2011
    ..Future research examining participants after traumatic events at different follow-up periods is needed to determine the specific influence of time interval since traumatization...
  24. doi request reprint Serotonin transporter gene variation and stressful life events impact processing of fear and anxiety
    Diana Armbruster
    Institute of Psychology II, Dresden University of Technology, Dresden, Germany
    Int J Neuropsychopharmacol 12:393-401. 2009
    ..The results replicate and emphasize the role of 5-HTTLPR and stress on the overall startle response as a possible genetically driven endophenotype for anxiety-related behaviour...
  25. doi request reprint Predicting cortisol stress responses in older individuals: influence of serotonin receptor 1A gene (HTR1A) and stressful life events
    Diana Armbruster
    Institute of Psychology II, Dresden University of Technology, Dresden, Germany
    Horm Behav 60:105-11. 2011
    ..The results further underscore the crucial role of functional serotonergic genetic variation as well as stressful events during critical stages of development on the acute stress response later in life...
  26. ncbi request reprint Psychosocial stress-induced activation of salivary alpha-amylase: an indicator of sympathetic activity?
    Nicolas Rohleder
    Biopsychology, Technical University of Dresden, Zellescher Weg 17, D 01069 Dresden, Germany
    Ann N Y Acad Sci 1032:258-63. 2004
    ..However, some questions remain to be answered; for example, what impact does salivary flow rate exert on stress-induced sAA activity?..
  27. doi request reprint Inflexibly focused under stress: acute psychosocial stress increases shielding of action goals at the expense of reduced cognitive flexibility with increasing time lag to the stressor
    Franziska Plessow
    Technische Universitat Dresden, Dresden, Germany
    J Cogn Neurosci 23:3218-27. 2011
    ..Our study provides evidence for a stress-induced time-dependent decrease of cognitive flexibility that might be related to changes in cortisol levels...
  28. doi request reprint Variation in genes involved in dopamine clearance influence the startle response in older adults
    Diana Armbruster
    Personality and Individual Differences, Institute of Psychology II, Dresden University of Technology, 01062, Dresden, Germany
    J Neural Transm 118:1281-92. 2011
    ..Although the functional significance of DAT1 VNTR is less defined, our results point to a potential influence of SLC6A3 on startle magnitude...
  29. doi request reprint Stathmin, a gene regulating neural plasticity, affects fear and anxiety processing in humans
    Burkhard Brocke
    Institute of Psychology II, Dresden University of Technology, Dresden, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:243-51. 2010
    ..We therefore conclude that STMN1 genotype has functional relevance for the acquisition and expression of basic fear and anxiety responses also in humans...
  30. doi request reprint Influence of functional tryptophan hydroxylase 2 gene variation and sex on the startle response in children, young adults, and older adults
    Diana Armbruster
    Institute of Psychology II, Dresden University of Technology, Dresden, Germany
    Biol Psychol 83:214-21. 2010
    ..The difference between TPH2 genotype groups also reached significance in the female subsample when including menstrual cycle phase. In contrast, there was no effect of TPH2 or a TPH2xsex interaction effect in children or in older adults...
  31. doi request reprint A striking pattern of cortisol non-responsiveness to psychosocial stress in patients with panic disorder with concurrent normal cortisol awakening responses
    Katja Petrowski
    Institute of Psychotherapy and Psychosomatic Medicine, School of Medicine, Technische Universitat Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Psychoneuroendocrinology 35:414-21. 2010
    ..While these patients show little or no alterations in basal ACTH and cortisol levels, it has been hypothesized that HPA hyperresponsivity was a trait in panic patients when exposed to novel and uncontrollable stimulation...
  32. ncbi request reprint The psychosocial stress-induced increase in salivary alpha-amylase is independent of saliva flow rate
    Nicolas Rohleder
    Department of Psychology, Dresden University of Technology, D 01069 Dresden, Germany
    Psychophysiology 43:645-52. 2006
    ..Results indicate that flow rate is not a confounder of stress-induced sAA activation and suggest that valid measurements of sAA can be obtained by salivettes without the need for assessment of flow rate...
  33. doi request reprint Chronic sleep curtailment impairs the flexible implementation of task goals in new parents
    Franziska Plessow
    Technische Universitat Dresden, Dresden, Germany Julius Maximilians Universität Würzburg, Wurzburg, Germany
    J Sleep Res 20:279-87. 2011
    ..With this study, we provide the first evidence for an impairment of the ability to flexibly implement task goals in chronically sleep-deprived new parents and, thus, for a link between chronic sleep curtailment and executive functions...
  34. ncbi request reprint No response of plasma substance P, but delayed increase of interleukin-1 receptor antagonist to acute psychosocial stress
    Nicolas Rohleder
    Department of Psychology, Dresden University of Technology, Zellescher Weg 17, D 01069 Dresden, Germany
    Life Sci 78:3082-9. 2006
    ..Further studies have to reveal the mechanisms involved in the stress-induced up regulation of IL-1ra...
  35. ncbi request reprint The hypothalamic-pituitary-adrenal (HPA) axis in habitual smokers
    Nicolas Rohleder
    Department of Psychology, Dresden University of Technology, Zellescher Weg 17, D 01069, Dresden, Germany
    Int J Psychophysiol 59:236-43. 2006
    ....
  36. doi request reprint Decreased hair cortisol concentrations in generalised anxiety disorder
    Susann Steudte
    Institute of Biological Psychology, Technische Universitaet Dresden, Dresden, Germany
    Psychiatry Res 186:310-4. 2011
    ....
  37. doi request reprint Classification criteria for distinguishing cortisol responders from nonresponders to psychosocial stress: evaluation of salivary cortisol pulse detection in panel designs
    Robert Miller
    Dr rer nat, Department of Psychology, Technische Universitat Dresden, D 01062 Dresden, Germany
    Psychosom Med 75:832-40. 2013
    ..For this, fixed threshold classification criteria, such as a 2.5-nmol/l baseline-to-peak increase, are frequently used. However, the performance of such criteria has not been systematically evaluated...
  38. pmc Intention retrieval and deactivation following an acute psychosocial stressor
    Moritz Walser
    Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    PLoS ONE 8:e85685. 2013
    ..Findings indicate that cognitive control processes subserving intention retrieval and deactivation after completion may be mostly preserved even under conditions of acute stress. ..
  39. doi request reprint Analysis of cortisol in hair--state of the art and future directions
    Tobias Stalder
    Department of Psychology, Technical University of Dresden, 01069 Dresden, Germany
    Brain Behav Immun 26:1019-29. 2012
    ..Given its unique characteristics, the use of hair analysis holds great promise to significantly enhance current understanding on the role of steroid hormones in psychoimmunological research...
  40. pmc Enhanced sympathetic arousal in response to FMRI scanning correlates with task induced activations and deactivations
    Markus Muehlhan
    Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    PLoS ONE 8:e72576. 2013
    ..It is of particular importance for pharmacological investigations studying adrenergic agents and the comparison of groups with different stress vulnerabilities like patients and controls or adolescents and adults. ..
  41. doi request reprint Impact of antenatal synthetic glucocorticoid exposure on endocrine stress reactivity in term-born children
    Nina Alexander
    Department of Psychology, Faculty of Science, Technische Universitat Dresden, Germany
    J Clin Endocrinol Metab 97:3538-44. 2012
    ..So far, the assessment of HPA-axis activity in offspring of mothers treated with synthetic GC has been limited to a time period shortly after birth, with prematurity being an important confound in most prior studies...
  42. doi request reprint The Trier Social Stress Test for Groups (TSST-G): A new research tool for controlled simultaneous social stress exposure in a group format
    Bernadette von Dawans
    Department of Psychology, Laboratory for Biological and Personality Psychology, University of Freiburg, Stefan Meier Strasse 8, D 79104 Freiburg, Germany
    Psychoneuroendocrinology 36:514-22. 2011
    ..The TSST-G provides a novel, effective, and economical protocol for experimental paradigms requiring simultaneous stress induction in multiple participants...
  43. doi request reprint Stress reduces use of negative feedback in a feedback-based learning task
    Antje Petzold
    Department of Psychology, Technische Universitat Dresden, D 01062 Dresden, Germany
    Behav Neurosci 124:248-55. 2010
    ..An enhancing effect of stress on use of positive feedback failed to reach significance. These findings suggest that stress acts differentially on the use of positive and negative feedback during learning...
  44. doi request reprint Visuospatial short-term memory explains deficits in tower task planning in high-functioning children with autism spectrum disorder
    Katharina Zinke
    Department of Psychology, Technical University Dresden, Dresden, Germany
    Child Neuropsychol 16:229-41. 2010
    ..Findings suggest that particularly reduced efficiency in visuospatial short-term memory is associated with Tower task planning deficits in children with HFA...
  45. doi request reprint The scanner as a stressor: evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging session
    Markus Muehlhan
    Chair of Biopsychology, Department of Psychology, Technische Universitat Dresden, Dresden, Germany
    Int J Psychophysiol 79:118-26. 2011
    ..No significant correlation between cortisol and thalamic activity was observed. Results indicate that an fMRI experiment may elicit subjective and neuroendocrine stress reactions that can influence functional activation patterns...
  46. ncbi request reprint Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder
    Nicolas Rohleder
    Department of Psychology, Institute of Experimental Psychology II, University of Dusseldorf, Dusseldorf, Germany
    Biol Psychiatry 55:745-51. 2004
    ..Alterations include various responses to HPA axis stimulation, different basal hormone levels, and changes in glucocorticoid receptor (GR) numbers on lymphocytes. The functional significance of these latter changes remains elusive...
  47. ncbi request reprint No effects of repeated forced wakings during three consecutive nights on morning cortisol awakening responses (CAR): a preliminary study
    Lucia Dettenborn
    Department of Biopsychology, TU Dresden, 01062 Dresden, Germany
    Psychoneuroendocrinology 32:915-21. 2007
    ..We aimed to investigate whether three experimentally induced awakenings during three consecutive nights would be associated with HPA-axis stimulation and an altered morning CAR...
  48. ncbi request reprint Effects of nutrition on neuro-endocrine stress responses
    Nicolas Rohleder
    Department of Psychology, Dresden University of Technology, Dresden, Germany
    Curr Opin Clin Nutr Metab Care 10:504-10. 2007
    ..This contradicts the classical view of the proposed primary glucocorticoid function of providing the individual with energy in fight-or-flight situations...