A R Heller

Summary

Affiliation: Technical University
Country: Germany

Publications

  1. ncbi request reprint [Thoracotomy and scoliosis surgery in a patient with a univentricular heart]
    A R Heller
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Dresden
    Anaesthesist 52:218-23. 2003
  2. doi request reprint Precision of traditional approaches for lumbar plexus block: impact and management of interindividual anatomic variability
    Axel R Heller
    Clinic of Anesthesiology and Intensive Care Medicine, Carl Gustav Carus University Hospital, University of Technology, Dresden, Germany
    Anesthesiology 111:525-32. 2009
  3. ncbi request reprint [Rigor mortis -- a definite sign of death?]
    A R Heller
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Dresden
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:225-9. 2005
  4. ncbi request reprint Modifying the baricity of local anesthetics for spinal anesthesia by temperature adjustment: model calculations
    Axel R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Anesthesiology 105:346-53. 2006
  5. ncbi request reprint A fine balance--one-lung ventilation in a patient with Eisenmenger syndrome
    A R Heller
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Harvard Medical International Associated Institution, Fetscherstrasse 74, D 01307 Dresden, Germany
    Br J Anaesth 92:587-90. 2004
  6. ncbi request reprint Pharmaconutrition with omega-3 fatty acids: status quo and further perspectives
    Axel R Heller
    Klinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Fetscherstrasse 74, D 01309 Dresden, Germany
    Mini Rev Med Chem 8:107-15. 2008
  7. ncbi request reprint Modulation of host defense by hydrocortisone in stress doses during endotoxemia
    Axel R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Fetscherstrasse 74, 01309 Dresden, Germany
    Intensive Care Med 29:1456-63. 2003
  8. ncbi request reprint Clusterin protects the lung from leukocyte-induced injury
    Axel R Heller
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, D 01307 Dresden, Germany
    Shock 20:166-70. 2003
  9. ncbi request reprint Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung
    A R Heller
    University Hospital Carl Gustav Carus, Harvard Medical International Associated Institution, Department of Anesthesiology and Intensive Care Medicine, Dresden, Germany
    Eur J Anaesthesiol 24:258-66. 2007
  10. ncbi request reprint [Impact of thoracic epidural analgesia on revenue for G-DRG M01B, OPS-301 5-604.0 (radical retropubic prostatectomy)]
    A R Heller
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Technische Universitat, Dresden
    Anaesthesist 54:1176-85. 2005

Detail Information

Publications44

  1. ncbi request reprint [Thoracotomy and scoliosis surgery in a patient with a univentricular heart]
    A R Heller
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Dresden
    Anaesthesist 52:218-23. 2003
    ....
  2. doi request reprint Precision of traditional approaches for lumbar plexus block: impact and management of interindividual anatomic variability
    Axel R Heller
    Clinic of Anesthesiology and Intensive Care Medicine, Carl Gustav Carus University Hospital, University of Technology, Dresden, Germany
    Anesthesiology 111:525-32. 2009
    ..These methods may be inaccurate in many cases. The aim of this study was to determine the accuracy of these traditional approaches and determine if modifications could increase their accuracy...
  3. ncbi request reprint [Rigor mortis -- a definite sign of death?]
    A R Heller
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Dresden
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:225-9. 2005
    ..To what extent basic life support by paramedics should commence when rigor and livores are present until physician DNR order, deserves further discussion...
  4. ncbi request reprint Modifying the baricity of local anesthetics for spinal anesthesia by temperature adjustment: model calculations
    Axel R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Anesthesiology 105:346-53. 2006
    ....
  5. ncbi request reprint A fine balance--one-lung ventilation in a patient with Eisenmenger syndrome
    A R Heller
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Harvard Medical International Associated Institution, Fetscherstrasse 74, D 01307 Dresden, Germany
    Br J Anaesth 92:587-90. 2004
    ..The diagnostic value of lung biopsy must be weighed against the possibility of life-threatening haemorrhage...
  6. ncbi request reprint Pharmaconutrition with omega-3 fatty acids: status quo and further perspectives
    Axel R Heller
    Klinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Fetscherstrasse 74, D 01309 Dresden, Germany
    Mini Rev Med Chem 8:107-15. 2008
    ..Clinical impact of fish oil based pharmaconutrition during critical inflammation processes and immune response in humans is thoroughly discussed...
  7. ncbi request reprint Modulation of host defense by hydrocortisone in stress doses during endotoxemia
    Axel R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Fetscherstrasse 74, 01309 Dresden, Germany
    Intensive Care Med 29:1456-63. 2003
    ..coli from blood and tissue under endotoxemic and non-endotoxemic conditions. DESIGN. Randomized, controlled trial...
  8. ncbi request reprint Clusterin protects the lung from leukocyte-induced injury
    Axel R Heller
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, D 01307 Dresden, Germany
    Shock 20:166-70. 2003
    ..Elevated levels of CLU during inflammation could reflect a compensatory organ protective mechanism. Further studies are required to elucidate the clinical impact of the observed organ-protective properties of CLU...
  9. ncbi request reprint Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung
    A R Heller
    University Hospital Carl Gustav Carus, Harvard Medical International Associated Institution, Department of Anesthesiology and Intensive Care Medicine, Dresden, Germany
    Eur J Anaesthesiol 24:258-66. 2007
    ..Tissue depletion of adenosine during endotoxaemia has previously been described in the lung. Therapeutic approaches to prevent adenosine depletion and the role of A1 and A2 receptor agonists, however, have not been investigated until now...
  10. ncbi request reprint [Impact of thoracic epidural analgesia on revenue for G-DRG M01B, OPS-301 5-604.0 (radical retropubic prostatectomy)]
    A R Heller
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Technische Universitat, Dresden
    Anaesthesist 54:1176-85. 2005
    ..0 (radical retropubic prostatectomy) as an example, our study identifies revenue-relevant patient characteristics and describes the impact of the perioperative application of thoracic epidural analgesia (TEA)...
  11. doi request reprint Pretreatment with perfluorohexane vapor attenuates fMLP-induced lung injury in isolated perfused rabbit lungs
    Jörg U Bleyl
    Clinic for Anaesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
    Exp Lung Res 36:342-51. 2010
    ..Vaporization of perfluorocarbons (PFCs) offers new therapeutic options, making use of their protective and anti-inflammatory properties in prophylaxis or in early treatment of acute lung injury...
  12. ncbi request reprint N(omega)-nitro-L-arginine methyl ester effects on neutrophil function and bacterial clearance
    Sebastian N Stehr
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Shock 22:180-5. 2004
    ..Therefore, in this model, we find sufficient evidence pointing to a possible cause for the deleterious effect of early nonselective NOS inhibition in critically ill patients...
  13. ncbi request reprint Spatial pulmonary flow distribution in rabbit isolated lungs is a poor representation of the situation in vivo
    M Hubler
    Department of Anaesthesiology and Intensive Care Medicine, Technical University Dresden, Carl Gustav Carus University Hospital, Fetscherstrasse 74, 01307 Dresden, Germany
    Clin Exp Pharmacol Physiol 34:269-73. 2007
    ..4. The results obtained from studies investigating Q (rel) distributions in isolated lung models must be interpreted cautiously because the isolated lung set-up significantly affects the spatial distribution of pulmonary flow...
  14. ncbi request reprint [Combined anesthesia with epidural catheter. A retrospective analysis of the perioperative course in patients ungoing radical prostatectomy]
    A R Heller
    Klinik und Poliklinik für Anaesthesiologie und Intensivmedizin, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden
    Anaesthesist 49:949-59. 2000
    ..Combination of GA and EA, especially TEA, appears to improve perioperative care of patients undergoing rPE, in terms of patients safety and comfort...
  15. ncbi request reprint N-acetylcysteine reduces respiratory burst but augments neutrophil phagocytosis in intensive care unit patients
    A R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Crit Care Med 29:272-6. 2001
    ..To evaluate whether NAC affects host defense mechanisms in critically ill patients, thus predisposing to increased risk of infection, the current study focuses on neutrophil phagocytotic and burst activity after treatment with NAC...
  16. ncbi request reprint Effects of IGM-enriched solution on polymorphonuclear neutrophil function, bacterial clearance, and lung histology in endotoxemia
    Sebastian N Stehr
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Shock 29:167-72. 2008
    ..Short-term IgM-enriched solution intervention had an especially beneficial effect on LPS-induced pulmonary histological changes...
  17. ncbi request reprint Insulin effects on myocardial function and bioenergetics in L-bupivacaine toxicity in the isolated rat heart
    S N Stehr
    Medical Faculty Carl Gustav Carus, Department of Anaesthesiology and Intensive Care Medicine, Dresden, Germany
    Eur J Anaesthesiol 24:340-6. 2007
    ..Using an isolated heart model, we therefore sought to further elucidate insulin effects in l-bupivacaine-induced myocardial depression...
  18. doi request reprint Effects of perfluorohexane vapor in the treatment of experimental lung injury
    Jörg U Bleyl
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Pulm Pharmacol Ther 23:450-5. 2010
    ....
  19. ncbi request reprint Misplacement of a psoas compartment catheter in the subarachnoid space
    Rainer J Litz
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Reg Anesth Pain Med 29:60-4. 2004
    ..This case report describes an unusual cause of misplacement of an indwelling catheter in the subarachnoid space after primary psoas compartment block in a patient undergoing total knee arthroplasty...
  20. ncbi request reprint Perfluorohexane vapor has only minor effects on spatial pulmonary blood flow distribution in isolated rabbit lungs
    Matthias Hübler
    Department of Anesthesiology and Intensive Care Medicine, Technical University Dresden, Germany
    Anesth Analg 100:1122-8. 2005
    ..However, in the PFH group a tendency towards redistribution of (Qrel) to more ventral lung areas was noted. Our results suggest that PFH vapor has no significant effects on redistribution of (Qrel) in isolated rabbit lungs...
  21. ncbi request reprint Epidural abscess after epidural catheter for pain release during pancreatitis
    A R Heller
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Acta Anaesthesiol Scand 44:1024-7. 2000
    ..Despite knowledge about compromised host defence in the course of diabetes mellitus and pancreatitis, epidural analgesia (EA) is recommended for pain management during pancreatitis...
  22. doi request reprint Pressure support ventilation and biphasic positive airway pressure improve oxygenation by redistribution of pulmonary blood flow
    Alysson R Carvalho
    Clinic of Anesthesiology and Intensive Care Medicine, University Clinic Carl Gustav Carus, Dresden, Germany
    Anesth Analg 109:856-65. 2009
    ..We evaluated the mechanisms behind the improvement of gas exchange with PSV and BIPAP...
  23. doi request reprint Effects of awareness and nociception on heart rate variability during general anaesthesia
    R Huhle
    Institute of Biomedical Engineering, Dresden Technical University, Dresden, Germany
    Physiol Meas 33:207-17. 2012
    ..However, the lack of steady-state ventilation/breathing in this study needs to be considered in future research. To be used for clinical anaesthesia monitoring our results have to be prospectively validated in clinical studies...
  24. doi request reprint [Perioperative visual loss after nonocular surgery]
    S Shmygalev
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Dresden, Deutschland
    Ophthalmologe 108:1067-76; quiz 1077. 2011
    ..This review updates readers on the incidence, suspected risk factors, diagnosis and treatment of POVL in the setting of nonocular surgery...
  25. ncbi request reprint Impact of n-3 fatty acid supplemented parenteral nutrition on haemostasis patterns after major abdominal surgery
    A R Heller
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Dresden, Germany
    Br J Nutr 87:S95-101. 2002
    ..No clinically significant differences were observed between the SO- and SO + FO- group. These findings suggest that infusion of fish oil in doses up to 0.2 g/kgBW per day is safe regarding coagulation and platelet function...
  26. doi request reprint [Inhaled anesthetics]
    M Deile
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Dresden, Fetscherstr 74, 01307, Dresden, Deutschland
    Anaesthesist 62:493-504. 2013
    ..Another promising inhalative anesthetic is xenon which fulfils many aspects of an ideal inhalative anesthetic. ..
  27. doi request reprint [Cardioprotection]
    M Damm
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Fetscherstrasse 74, Dresden, Germany
    Anaesthesist 60:1065-80; quiz 1081-2. 2011
    ..Therefore regional anesthesia should be used as a part of multimodal therapy concepts to lower the risk of perioperative cardiovascular events...
  28. doi request reprint [The family-friendly hospital: (how) does it work?]
    A R Heller
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, 01307, Dresden, Deutschland
    Anaesthesist 58:571-81. 2009
    ..This article discusses the necessity, opportunities and threads of family-oriented hospital management and fields of action for anaesthesia departments...
  29. doi request reprint [Perioperative visual loss after nonocular surgery]
    S Shmygalev
    Klinik und Poliklinik für Anaesthesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, Dresden, Germany
    Anaesthesist 60:683-94. 2011
    ..This review updates readers on the incidence, suspected risk factors, diagnosis and treatment of POVL in the setting of nonocular surgery...
  30. ncbi request reprint Fish or chips?
    Axel R Heller
    Department of Anesthesiology and Intensive Care Medicine, University of Technology, D 01307 Dresden, Germany
    News Physiol Sci 18:50-4. 2003
    ..Encouraging improvements in critically ill patients were observed after nutritional replacement of long-chain omega-6 fatty acids with long-chain omega-3-fatty acids, contained in fish oil...
  31. ncbi request reprint High-resolution ultrasound-guided high interscalene plexus block for carotid endarterectomy
    Thomas Roessel
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany
    Reg Anesth Pain Med 32:247-53. 2007
    ....
  32. doi request reprint Epidural ropivacaine concentrations for intraoperative analgesia during major upper abdominal surgery: a prospective, randomized, double-blinded, placebo-controlled study
    Periklis Panousis
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Fetscherstr 74, 01307 Dresden, Germany
    Anesth Analg 108:1971-6. 2009
    ..We performed this study among patients undergoing major upper abdominal surgery under combined TEA and general anesthesia...
  33. ncbi request reprint Omega-3 fatty acid effects on biochemical indices following cancer surgery
    Sebastian N Stehr
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Fetscherstrasse 74, D 01309 Dresden, Germany
    Clin Chim Acta 373:1-8. 2006
    ..This paper is a review of recent developments in the field of nutrition in cancer patients with emphasis on the acute phase response following cancer surgery and the beneficial aspects of fish oil administration...
  34. doi request reprint Reversal of central nervous system and cardiac toxicity after local anesthetic intoxication by lipid emulsion injection
    Rainer J Litz
    Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, University of Technology, Fetscherstr 74, 01307 Dresden, Germany
    Anesth Analg 106:1575-7, table of contents. 2008
    ..Signs of toxicity resolved and the patient underwent the scheduled surgical procedure uneventfully under brachial plexus blockade...
  35. ncbi request reprint Anticancer actions of omega-3 fatty acids--current state and future perspectives
    Martina Wendel
    Department of Physiology, Medical Faculty Carl Gustav Carus, University of Technology, Dresden, Germany
    Anticancer Agents Med Chem 9:457-70. 2009
    ....
  36. doi request reprint [Standard operating procedures and operating room management: Improvement of patient safety and the efficiency of processes]
    Jörg U Bleyl
    Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitatsklinikum Carl Gustav Carus, Technische Universitat, Dresden, Deutschland
    Wien Med Wochenschr 158:595-602. 2008
    ..SOPs lead to a standardisation of workflow in the OR and in patient treatment modalities. This guaranties a high quality in patient care and more safety despite an increase in work-load...
  37. ncbi request reprint Omega-3 fatty acids improve the diagnosis-related clinical outcome
    Axel R Heller
    Department of Anesthesiology and Critical Care Medicine, The University Hospital Carl Gustav Carus, Dresden, Germany
    Crit Care Med 34:972-9. 2006
    ..The aim of this study was to evaluate dose-dependent effects of parenteral supplementation of a 10% fish oil emulsion (Omegaven, Fresenius-Kabi, Bad Homburg, Germany) on diagnosis- and organ failure-related outcome...
  38. ncbi request reprint Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients
    Axel R Heller
    Department of Anesthesiology and Critical Care Medicine, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany
    Int J Cancer 111:611-6. 2004
    ..1 +/- 2.2 kg was absent in the FO group. After major abdominal tumor surgery, FO supplementation improved liver and pancreas function, which might have contributed to the faster recovery of patients...
  39. ncbi request reprint Lipoproteins in inflammation and sepsis. II. Clinical aspects
    Martina Wendel
    Department of Anesthesiology and Critical Care Medicine, Carl Gustav Carus University Hospital, Fetscherstrasse 74, Dresden, Germany
    Intensive Care Med 33:25-35. 2007
    ....
  40. ncbi request reprint What is the definite merit of clonidine premedication in patients with sleep apnea?
    Carla B E S Hennig
    Anesth Analg 103:1590-1; author reply 1591. 2006
  41. ncbi request reprint Why do orthopedic patients have a higher incidence of serious complications after central neuraxial blockade?
    Axel R Heller
    Anesthesiology 102:1286; author reply 1287-8. 2005
  42. ncbi request reprint Omega-3 alpha linolenic acid does not reflect the entire omega-3 fatty acid family
    Axel R Heller
    Anesth Analg 102:1289; author reply 1289-90. 2006
  43. ncbi request reprint Comparing the steam engine with a horse-drawn carriage?
    Axel R Heller
    Anesth Analg 104:994-5. 2007
  44. ncbi request reprint The effects of electromyographic activity on the bispectral index during combined anesthesia
    Periklis Panousis
    Anesth Analg 103:1605. 2006