Klaus Tatsch

Summary

Country: Germany

Publications

  1. doi request reprint Positron emission tomography in diagnosis and differential diagnosis of Parkinson's disease
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe Inc, Karlsruhe, Germany
    Neurodegener Dis 7:330-40. 2010
  2. doi request reprint Nigrostriatal dopamine terminal imaging with dopamine transporter SPECT: an update
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe, Inc, Karlsruhe, Germany
    J Nucl Med 54:1331-8. 2013
  3. pmc No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT
    Gerda Thomsen
    Neurobiology Research Unit 9201, Rigshospitalet and Copenhagen University Hospital, Blegdamsvej 9, Copenhagen 2100, Denmark
    EJNMMI Res 3:39. 2013
  4. pmc Predictive and prognostic value of circulating nucleosomes and serum biomarkers in patients with metastasized colorectal cancer undergoing Selective Internal Radiation Therapy
    Yvonne Nadine Fahmueller
    Institute of Clinical Chemistry, University Hospital, Munich Grosshadern, Germany
    BMC Cancer 12:5. 2012
  5. ncbi request reprint Quantitative approaches to dopaminergic brain imaging
    K Tatsch
    Department of Nuclear Medicine, Municipal Hospital, Karlsruhe Inc, Karlsruhe, Germany
    Q J Nucl Med Mol Imaging 56:27-38. 2012
  6. doi request reprint Extrapyramidal syndromes: PET and SPECT
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe Inc, Karlsruhe, Germany
    Neuroimaging Clin N Am 20:57-68. 2010
  7. ncbi request reprint FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, Munich, Germany
    Eur J Nucl Med Mol Imaging 34:1933-42. 2007
  8. doi request reprint Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine D₂/₃ receptors in rats with prolonged [¹⁸F]-DMFP infusions
    Erik Mille
    Department of Nuclear Medicine, University Hospital of the Ludwig Maximilians University of Munich, Munich, Germany
    Synapse 66:705-13. 2012
  9. ncbi request reprint Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Munich, Germany
    J Nucl Med 47:393-403. 2006
  10. ncbi request reprint Presynaptic dopaminergic function in patients with restless legs syndrome: are there common features with early Parkinson's disease?
    Rainer Linke
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    Mov Disord 19:1158-62. 2004

Collaborators

Detail Information

Publications33

  1. doi request reprint Positron emission tomography in diagnosis and differential diagnosis of Parkinson's disease
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe Inc, Karlsruhe, Germany
    Neurodegener Dis 7:330-40. 2010
    ..This overview discusses the important PET applications in the field with a main emphasis on their clinical utilization but also highlights scientific applications which may grant further insights in the pathophysiology of PD and aPS...
  2. doi request reprint Nigrostriatal dopamine terminal imaging with dopamine transporter SPECT: an update
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe, Inc, Karlsruhe, Germany
    J Nucl Med 54:1331-8. 2013
    ..Finally, some remarks deal with the economic aspects of the use of these imaging techniques in the clinical setting. ..
  3. pmc No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT
    Gerda Thomsen
    Neurobiology Research Unit 9201, Rigshospitalet and Copenhagen University Hospital, Blegdamsvej 9, Copenhagen 2100, Denmark
    EJNMMI Res 3:39. 2013
    ..We used the database to test the hypothesis that striatal DAT availability is changed in active smokers compared to non-smokers and ex-smokers...
  4. pmc Predictive and prognostic value of circulating nucleosomes and serum biomarkers in patients with metastasized colorectal cancer undergoing Selective Internal Radiation Therapy
    Yvonne Nadine Fahmueller
    Institute of Clinical Chemistry, University Hospital, Munich Grosshadern, Germany
    BMC Cancer 12:5. 2012
    ..Markers for prediction of therapy response and prognosis are needed for the individual management of those patients undergoing SIRT...
  5. ncbi request reprint Quantitative approaches to dopaminergic brain imaging
    K Tatsch
    Department of Nuclear Medicine, Municipal Hospital, Karlsruhe Inc, Karlsruhe, Germany
    Q J Nucl Med Mol Imaging 56:27-38. 2012
    ..Finally, some thoughts regarding the impact of standardization and harmonization of protocols for imaging and processing will be discussed, including the use of normal data bases for reference...
  6. doi request reprint Extrapyramidal syndromes: PET and SPECT
    Klaus Tatsch
    Department of Nuclear Medicine, Municipal Hospital Karlsruhe Inc, Karlsruhe, Germany
    Neuroimaging Clin N Am 20:57-68. 2010
    ..This article gives an overview of the current positron emission tomography and single photon emission computed tomography applications for diagnosing ES and focuses on their use in clinical practice...
  7. ncbi request reprint FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, Munich, Germany
    Eur J Nucl Med Mol Imaging 34:1933-42. 2007
    ..Treatment and prognosis of gliomas depend on their histological tumour grade. The aim of the study was to evaluate the potential of [(18)F]fluoroethyltyrosine (FET) PET for non-invasive tumour grading in untreated patients...
  8. doi request reprint Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine D₂/₃ receptors in rats with prolonged [¹⁸F]-DMFP infusions
    Erik Mille
    Department of Nuclear Medicine, University Hospital of the Ludwig Maximilians University of Munich, Munich, Germany
    Synapse 66:705-13. 2012
    ..Based on this phenomenon, we developed an analytic method compensating for the effects of progressive cranial labeling on the estimation of specific binding in striatum...
  9. ncbi request reprint Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Munich, Germany
    J Nucl Med 47:393-403. 2006
    ....
  10. ncbi request reprint Presynaptic dopaminergic function in patients with restless legs syndrome: are there common features with early Parkinson's disease?
    Rainer Linke
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    Mov Disord 19:1158-62. 2004
    ..Our results do not strengthen an identical pathophysiologic pathway between RLS and PD on the level of nigrostriatal presynaptic terminal function...
  11. ncbi request reprint Is iterative reconstruction an alternative to filtered backprojection in routine processing of dopamine transporter SPECT studies?
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 46:1804-11. 2005
    ..The aim of this study was to investigate whether the use of an iterative reconstruction algorithm (ordered-subset expectation maximization [OSEM]) may provide results comparable to or even better than those obtained by standard FBP...
  12. doi request reprint The value of the dopamine D2/3 receptor ligand 18F-desmethoxyfallypride for the differentiation of idiopathic and nonidiopathic parkinsonian syndromes
    Christian la Fougere
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 51:581-7. 2010
    ..On the basis of the superior sensitivity of PET, we hypothesized that (18)F-DMFP should have properties for the differential diagnosis of these syndromes superior to what has been reported for the more conventional SPECT procedures...
  13. pmc Serial O-(2-[(18)F]fluoroethyl)-L: -tyrosine PET for monitoring the effects of intracavitary radioimmunotherapy in patients with malignant glioma
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 33:792-800. 2006
    ....
  14. ncbi request reprint Clinical testing of an optimized software solution for an automated, observer-independent evaluation of dopamine transporter SPECT studies
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 46:1109-18. 2005
    ....
  15. doi request reprint Implementation of the European multicentre database of healthy controls for [(123)I]FP-CIT SPECT increases diagnostic accuracy in patients with clinically uncertain parkinsonian syndromes
    Nathalie L Albert
    Department of Nuclear Medicine, University of Munich, Ziemssenstr 1, 80336, Munich, Germany
    Eur J Nucl Med Mol Imaging 43:1315-22. 2016
    ....
  16. ncbi request reprint Does combined imaging of the pre- and postsynaptic dopaminergic system increase the diagnostic accuracy in the differential diagnosis of parkinsonism?
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 34:1265-73. 2007
    ..Therefore, the aim of the study was to introduce new semi-quantitative parameters and evaluate their ability to discriminate between Parkinson's disease (IPS) and non-idiopathic parkinsonian syndromes (non-IPS)...
  17. ncbi request reprint Value of 99mTc-TRODAT-1 SPECT to predict clinical response to methylphenidate treatment in adults with attention deficit hyperactivity disorder
    Christian la Fougere
    Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
    Nucl Med Commun 27:733-7. 2006
    ..In a previous study, binding of Tc-TRODAT-1 to the dopamine transporter (DAT) was found to be higher in patients with attention deficit hyperactivity disorder (ADHD) as compared to healthy controls...
  18. ncbi request reprint Extended studies of the striatal uptake of 99mTc-NC100697 in healthy volunteers
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 48:27-34. 2007
    ..This study evaluates a new formulation of a (99m)Tc-labeled tropane derivate, (99m)Tc-NC100697, in a human volunteer study...
  19. doi request reprint Endogenous competition against binding of [(18)F]DMFP and [(18)F]fallypride to dopamine D(2/3) receptors in brain of living mouse
    Axel Rominger
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    Synapse 64:313-22. 2010
    ....
  20. ncbi request reprint Cross-camera comparison of SPECT measurements of a 3-D anthropomorphic basal ganglia phantom
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 33:495-502. 2006
    ..The latter may serve as a model for human studies of the dopaminergic system...
  21. ncbi request reprint Diagnostic performance of a 3-D automated quantification method of dopamine D2 receptor SPECT studies in the differential diagnosis of parkinsonism
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, Ludwig Maximilians University of Munich, Germany
    Nucl Med Commun 26:39-43. 2005
    ..Assessment of post-synaptic D2 receptors with 123I-IBZM SPECT is helpful in distinguishing idiopathic (IPS) from other parkinsonian syndromes (non-IPS)...
  22. pmc [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects
    Walter Koch
    Department of Nuclear Medicine, Ludwig Maximilians University, Munich, Germany
    J Psychiatry Neurosci 32:234-40. 2007
    ..The aim of this study was to investigate serotonin transporter availability in patients with BPD as a marker of the central serotonergic system...
  23. ncbi request reprint Influence of movement on FP-CIT SPECT quantification: a Monte Carlo based simulation
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Germany
    Nucl Med Commun 28:603-14. 2007
    ..The aim of this study was to obtain detailed insight into the effects of head motion on the specific striatal binding of I-FP-CIT based on Monte Carlo simulations...
  24. doi request reprint Imaging of the dopaminergic system in differential diagnosis of dementia
    Klaus Tatsch
    Department of Nuclear Medicine, University of Munich Hospital Campus Grosshadern, Marchioninistrasse 15, Munich, Germany
    Eur J Nucl Med Mol Imaging 35:S51-7. 2008
    ..This review discusses the findings of studies specifically dealing with imaging of the dopaminergic system in the differential diagnosis of dementia...
  25. ncbi request reprint D2 receptor occupancy during high- and low-dose therapy with the atypical antipsychotic amisulpride: a 123I-iodobenzamide SPECT study
    Christian la Fougere
    Department of Nuclear Medicine, Ludwig Maximillians University of Munich, Ziemssenstrasse 1, 80336 Munich, Germany
    J Nucl Med 46:1028-33. 2005
    ..The aim of this study was to assess striatal dopamine D(2) receptor availability by means of (123)I-iodobenzamide (IBZM) SPECT in patients treated with high and low doses of this atypical antipsychotic drug...
  26. doi request reprint Iterative reconstruction or filtered backprojection for semi-quantitative assessment of dopamine D₂ receptor SPECT studies?
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Marchioninistr 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 38:1095-103. 2011
    ....
  27. ncbi request reprint Selective internal radiation therapy with SIR-Spheres in patients with nonresectable liver tumors
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, 81377 Munich, Germany
    Cancer Biother Radiopharm 20:200-8. 2005
    ..The aim of this study was to evaluate the feasibility and efficacy of this selective internal radiation therapy (SIRT)...
  28. ncbi request reprint Value of O-(2-[18F]fluoroethyl)- L-tyrosine PET for the diagnosis of recurrent glioma
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Marchioninistr 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 31:1464-70. 2004
    ..The aim of this study was to establish the diagnostic value of O-(2-[18F]fluoroethyl)- L-tyrosine (FET) PET in recurrent gliomas...
  29. ncbi request reprint Cortical hypometabolism and crossed cerebellar diaschisis suggest subcortically induced disconnection in CADASIL: an 18F-FDG PET study
    Klaus Tatsch
    Department of Nuclear Medicine, Klinikum Grosshadern, Ludwig Maximilians University Munich, Munich, Germany
    J Nucl Med 44:862-9. 2003
    ..The purpose of this study was to evaluate with (18)F-FDG PET whether regional cerebral metabolic rate of glucose (rCMRglc) is altered in CADASIL patients and, if so, whether there is evidence of subcortically induced disconnection...
  30. doi request reprint Reduction in camera-specific variability in [(123)I]FP-CIT SPECT outcome measures by image reconstruction optimized for multisite settings: impact on age-dependence of the specific binding ratio in the ENC-DAT database of healthy controls
    Ralph Buchert
    Department of Nuclear Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur J Nucl Med Mol Imaging 43:1323-36. 2016
    ..The secondary aim was to evaluate binding in whole brain (excluding striatum) as a reference for quantitative analysis...
  31. doi request reprint Extrastriatal binding of [¹²³I]FP-CIT in the thalamus and pons: gender and age dependencies assessed in a European multicentre database of healthy controls
    Walter Koch
    Department of Nuclear Medicine, University of Munich, Marchioninistr 15, 81377, Munich, Germany
    Eur J Nucl Med Mol Imaging 41:1938-46. 2014
    ..The aim of this study was to systematically evaluate extrastriatal binding (predominantly due to SERT) and its age and gender dependencies in a large cohort of healthy controls...
  32. ncbi request reprint Prokinetic therapy: what can be measured by gastric scintigraphy?
    Rainer Linke
    Department of Nuclear Medicine, University of Munich, Germany
    Nucl Med Commun 26:527-33. 2005
    ..To evaluate whether gastric scintigraphy with quantitative analysis of gastric peristalsis may be a useful tool for documenting the effects of prokinetic therapy...
  33. ncbi request reprint Can SPET imaging of dopamine uptake sites replace PET imaging in Parkinson's disease? For
    Klaus Tatsch
    Department of Nuclear Medicine, Klinikum Grosshadern, Ludwig Maximilians University Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 29:711-4. 2002