A Stoykova

Summary

Country: Germany

Publications

  1. pmc Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain
    Andreas Zembrzycki
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, Am Fassberg, 37077 Goettingen, Germany
    Neural Dev 2:8. 2007
  2. pmc Er81 is a downstream target of Pax6 in cortical progenitors
    Tran Cong Tuoc
    Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    BMC Dev Biol 8:23. 2008
  3. ncbi request reprint Increase in reelin-positive cells in the marginal zone of Pax6 mutant mouse cortex
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, D 37077 Gottingen, Germany
    Cereb Cortex 13:560-71. 2003
  4. ncbi request reprint Pax6 modulates the dorsoventral patterning of the mammalian telencephalon
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, 37077 Gottingen, Germany
    J Neurosci 20:8042-50. 2000
  5. ncbi request reprint Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain
    A Stoykova
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Development 124:3765-77. 1997
  6. ncbi request reprint Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression
    V Tarabykin
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    Development 128:1983-93. 2001
  7. ncbi request reprint Forebrain patterning defects in Small eye mutant mice
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Gottingen, Germany
    Development 122:3453-65. 1996
  8. ncbi request reprint Pax6 controls radial glia differentiation in the cerebral cortex
    M Gotz
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, Federal Republic of Germany
    Neuron 21:1031-44. 1998
  9. ncbi request reprint Efficient gene trap screening for novel developmental genes using IRES beta geo vector and in vitro preselection
    P Bonaldo
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, 37077, Germany
    Exp Cell Res 244:125-36. 1998
  10. ncbi request reprint Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity
    B Kammandel
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg, Gottingen, D 37077, Germany
    Dev Biol 205:79-97. 1999

Collaborators

Detail Information

Publications21

  1. pmc Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain
    Andreas Zembrzycki
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, Am Fassberg, 37077 Goettingen, Germany
    Neural Dev 2:8. 2007
    ..Furthermore, Sp8 is required during corticogenesis to sustain a normal progenitor pool, and to control preplate splitting, as well as the specification of cellular diversity within distinct cortical layers...
  2. pmc Er81 is a downstream target of Pax6 in cortical progenitors
    Tran Cong Tuoc
    Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    BMC Dev Biol 8:23. 2008
    ..In this study, we investigated the transcriptional regulation of Er81 and provide evidence that Er81 is a direct target of Pax6...
  3. ncbi request reprint Increase in reelin-positive cells in the marginal zone of Pax6 mutant mouse cortex
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, D 37077 Gottingen, Germany
    Cereb Cortex 13:560-71. 2003
    ..Taken together, these experiments further elucidate how patterning of the forebrain by the transcription factor Pax6 regulates the specification of distinct neuronal subtypes in the cortical MZ...
  4. ncbi request reprint Pax6 modulates the dorsoventral patterning of the mammalian telencephalon
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, 37077 Gottingen, Germany
    J Neurosci 20:8042-50. 2000
    ..Together the results demonstrate that Pax6 has an essential role for the modulation of the dorsoventral patterning of the embryonic telencephalon, influencing thereby the forebrain morphogenesis...
  5. ncbi request reprint Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain
    A Stoykova
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Development 124:3765-77. 1997
    ..These data suggest a link between the transcription factor, Pax6, R-cadherin expression, cellular adhesion and boundary formation between developing forebrain regions...
  6. ncbi request reprint Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression
    V Tarabykin
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    Development 128:1983-93. 2001
    ..Taken together our data suggest that while the specification of deep cortical layers occurs in the ventricular zone, the SVZ is important for the proper specification of upper layers...
  7. ncbi request reprint Forebrain patterning defects in Small eye mutant mice
    A Stoykova
    Max Planck Institute of Biophysical Chemistry, Gottingen, Germany
    Development 122:3453-65. 1996
    ..Our results are discussed in light of changes in adhesive properties in the Sey brain that might control segregation, assembly and cell migration of progenitors of specific forebrain regions...
  8. ncbi request reprint Pax6 controls radial glia differentiation in the cerebral cortex
    M Gotz
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, Federal Republic of Germany
    Neuron 21:1031-44. 1998
    ..Our results suggest that Pax6 plays an essential role in the differentiation of cortical radial glia. Thus, despite their widespread distribution, radial glia cells are regionally specified in the developing CNS...
  9. ncbi request reprint Efficient gene trap screening for novel developmental genes using IRES beta geo vector and in vitro preselection
    P Bonaldo
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, 37077, Germany
    Exp Cell Res 244:125-36. 1998
    ..These results suggest that a combination of IRESbetageo vector and in vitro preselection is more effective for the capture and mutation of a large number of developmental genes...
  10. ncbi request reprint Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity
    B Kammandel
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg, Gottingen, D 37077, Germany
    Dev Biol 205:79-97. 1999
    ..Corresponding regulatory elements from pufferfish are able to mimic the reporter expression in transgenic mice. Thus, the results indicate a structural and functional conservation of the Pax6 regulatory elements in the vertebrate genome...
  11. ncbi request reprint Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system
    A Stoykova
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, Germany
    Dev Dyn 212:198-213. 1998
    ....
  12. ncbi request reprint Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family
    A Bosse
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Gottingen, Germany
    Dev Dyn 218:160-74. 2000
    ..Together, with the data obtained from the chromosomal mapping analysis, the results indicate that these genes have appeared in vertebrates during evolution as a result of gene duplication...
  13. ncbi request reprint Roles of Pax-genes in developing and adult brain as suggested by expression patterns
    A Stoykova
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    J Neurosci 14:1395-412. 1994
    ....
  14. ncbi request reprint Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice
    A Mansouri
    Department of Molecular Cell Biology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Development 122:831-8. 1996
    ..No obvious phenotype could be detected in the central nervous system and skeletal muscle. Functional redundancy between Pax7 and Pax3 is discussed...
  15. ncbi request reprint Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities
    A Pires-daSilva
    Department of Molecular Cell Biology, Max Planck for Biophysical Chemistry, D 37077 Gottingen, Germany
    Dev Biol 233:319-28. 2001
    ..Our findings suggest that SPNR plays an important role in normal spermatogenesis and sperm function. Thus, the Spnr(GT/GT) mutant male mouse provides a unique model for some human male infertility cases...
  16. pmc Evidence for the stochastic integration of gene trap vectors into the mouse germline
    K Chowdhury
    Department of Molecular Cell Biology, Max Planck Institute of Biophysical Chemistry, Am Fassberg, D 37077 Gottingen, Germany
    Nucleic Acids Res 25:1531-6. 1997
    ..Using currently available methods or modifications of them, it should be feasible to do a large scale cloning of trapped genes from the mouse ES cell lines...
  17. ncbi request reprint Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels
    C Gonzalez-Billault
    Centro de Biologia Molecular, Universidad Autonoma de Madrid, Spain
    Mol Cell Neurosci 16:408-21. 2000
    ..Analyses of these mice indicate the presence of several neural defects and suggest the participation of MAP1B in neuronal migration...
  18. ncbi request reprint Pax: gene regulators in the developing nervous system
    G Chalepakis
    Max Planck Institut fur biophysikalische Chemie, Abteilung Molekulare Zellbiologie, Gottingen, Germany
    J Neurobiol 24:1367-84. 1993
    ..Pax proteins can transform cells in culture which then form tumours following injection in nude mice. Consistent with this activity, PAX3 has been recently implicated in the generation of the tumour alveolar rhabdomyosarcoma...
  19. pmc An alpha-E-catenin gene trap mutation defines its function in preimplantation development
    M Torres
    Abteilung Molekulare Zellbiologie, Max Planck Institut fur biophysikalische Chemie, Gottingen, Germany
    Proc Natl Acad Sci U S A 94:901-6. 1997
    ....
  20. ncbi request reprint The leukemic oncogene tal-2 is expressed in the developing mouse brain
    S Mori
    Department of Molecular Genetics, Kyoto University Graduate School of Medicine, Shogoin Kawahara cho 53, Kyoto 606 8507, Japan
    Brain Res Mol Brain Res 64:199-210. 1999
    ..The tal-2 messages were barely detectable in the brain at birth. These results suggest that tal-1 and tal-2 are involved in the development of specific areas of the central nervous system...
  21. ncbi request reprint Pax genes in development
    A Mansouri
    Max Plank Institut für biophysikalische Chemie, Abteilung Molekulare Zellbiologie, Gottingen, Germany
    J Cell Sci Suppl 18:35-42. 1994
    ..To date three Pax genes have been shown to be mutated in undulated, Splotch and small eye, respectively. In man, Pax-3 is mutated in the Waardenburg syndrome, while in aniridia Pax-6 is mutated...