Research Topics
| M StorrSummaryCountry: Germany Publications
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Detail Information
Publications
Endogenous CCK depresses contractile activity within the ascending myenteric reflex pathway of rat ileumM Storr
Department of Internal Medicine II, Technical University of Munich, Ismaningerstrasse 22, 81675 Munich, Germany
Neuropharmacology 44:524-32. 2003..Thus in experiments investigating more complex neuronal circuits, experiments with antagonists should be regarded as more specific...- Characterization of vagal input to the rat esophageal muscleM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Auton Neurosci 91:1-9. 2001..Therefore, the physiological relevance of the immunohistochemical findings remain unclear... 
Cannabinoid 1 receptors modulate intestinal sensory and motor function in ratB Yuce
Department of Internal Medicine II, Ludwig Maximilians University, 81377 Munich, Germany
Neurogastroenterol Motil 22:672-e205. 2010..The underlying mechanisms are not well characterized. We aimed to determine whether the cannabinoid-1 (CB(1)) receptor modulates intestinal afferent nerve discharge and the peristaltic reflex...- Mechanisms of alpha,beta-methylene atp-induced inhibition in rat ileal smooth muscle: involvement of intracellular Ca2+ stores in purinergic inhibitionM Storr
Department of Internal Medicine, Technical University of Munich, Germany
Clin Exp Pharmacol Physiol 27:771-9. 2000.... - Melatonin reduces non-adrenergic, non-cholinergic relaxant neurotransmission by inhibition of nitric oxide synthase activity in the gastrointestinal tract of rodents in vitroM Storr
Department of Internal Medicine II, Technical University of Munich, Munich, Germany
J Pineal Res 33:101-8. 2002..The presence of mt1 receptor transcripts adds supportive evidence for a possible physiological role of melatonin within the enteric nervous system... - Pathophysiology and pharmacological treatment of gastroesophageal reflux diseaseM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Dig Dis 18:93-102. 2000..The following article gives an overview regarding current concepts of the pathophysiology and pharmacological treatment of GERD... - Inhibition of small conductance K+ -channels attenuated melatonin-induced relaxation of serotonin-contracted rat gastric fundusM Storr
Department of Internal Medicine II, Technical University of Munich, Munchen, Germany
Can J Physiol Pharmacol 78:799-806. 2000..This suggests that melatonin may be another transmitter candidate for the apamin sensitive responses within the gastrointestinal tract... - Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colonM Storr
Gap, Department of Internal Medicine II, Technical University of Munich, 81675 Munich, Germany
Am J Physiol Gastrointest Liver Physiol 286:G110-7. 2004..The significant increase in EJP in CB1-deficient mice strongly suggests a physiological involvement of CB1 in excitatory cholinergic neurotransmission... - Modulatory effect of endogenous and exogenous opioids on the excitatory reflex pathway of the rat ileumH D Allescher
Department of Internal Medicine II, Technical University of Munich, Munich, Germany
Neuropeptides 34:62-8. 2000..Thus, mu- and kappa-receptors seem to be involved in regulating the contraction strength of the ascending reflex, whereas both mu- and delta-receptors seem to be involved in the timing of the reflex response... - Okadaic acid inhibits relaxant neural transmission in rat gastric fundus in vitroM Storr
Gap, Department of Internal Medicine II, Technical University of Munich, Ismaningerstr. 22, Munich, Germany
Acta Physiol Scand 175:29-36. 2002..The potential roles of protein phosphatases on NANC neurotransmission remain to be clarified in detail, as this might offer a new pathway for modulating smooth-muscle function... - Treatment of achalasia: botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-UpH D Allescher
Department of Internal Medicine II, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munich, Germany
Endoscopy 33:1007-17. 2001..The aim of the present study was to test the effectiveness, the long-term outcome and the cumulative costs of BTX injection in consecutive patients with symptomatic achalasia in comparison with pneumatic balloon dilation... - Effect of opioid active therapeutics on the ascending reflex pathway in the rat ileumH D Allescher
Department of Internal Medicine II, Technical University of Munich, Ismaningerstr 22, 81675 Munich, Germany
Neuropeptides 34:181-6. 2000..Thus casomorphins could have a local effect on the gut wall with no need for systemic absorption. This might be used for a possible therapeutic application... - Endomorphins 1 and 2 reduce relaxant non-adrenergic, non-cholinergic neurotransmission in rat gastric fundusM Storr
Department of Internal Medicine II, Technical University of Munich, 81675 Munich, Germany
Life Sci 71:383-9. 2002..The physiological relevance of these findings remains to be established, since the data presented suggest that the endomorphins act as neuromodulators within NANC relaxant neurotransmission... - Current concepts on pathophysiology, diagnosis and treatment of diffuse oesophageal spasmM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Drugs 61:579-91. 2001.... - STW 5 (Iberogast) and its individual herbal components modulate intestinal electrophysiology of miceA Sibaev
Department of Internal Medicine II, Ludwig-Maximilians University of Munich, Germany
Phytomedicine 13:80-9. 2006..These effects represent a summation effect of different constituents of this phytotherapeuticum and prove that STW 5 has characteristic effects on intestinal electrophysiology... - Pharmacoeconomic issues of the treatment of gastroesophageal reflux diseaseM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Expert Opin Pharmacother 2:1099-108. 2001.... - Simultaneous perforation of three major liver blood vessels by percutaneous transhepatic biliary drainageR Fritsch
Department of Internal Medicine II, Technical University of Munich, Germany
Endoscopy 34:844. 2002 - Effect of cannabinoids on neural transmission in rat gastric fundusM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Can J Physiol Pharmacol 80:67-76. 2002..The involved cannabinoid receptors are most likely located on neuronal structures. The present study also provides evidence that more than one receptor type is involved... - Treatment of symptomatic diffuse esophageal spasm by endoscopic injections of botulinum toxin: a prospective study with long-term follow-upM Storr
Department of Internal Medicine II, Technical University of Munich, Germany
Gastrointest Endosc 54:754-9. 2001..CONCLUSIONS: BTX injection at several levels of the tubular esophagus is an effective treatment for patients with symptoms caused by diffuse esophageal spasm. Symptom relapse can be effectively treated by repeated BTX injection... 
Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humansJ Schirra
Department of Internal Medicine II, Clinical Research Unit, Ludwig Maximilians University, Marchioninistr 15, Munich 81377, Germany
Gut 55:243-51. 2006..Exogenous use of the intestinal hormone glucagon-like peptide 1 (GLP-1) lowers glycaemia by stimulation of insulin, inhibition of glucagon, and delay of gastric emptying...- Endoscopic treatment of a Zenker's diverticulum using argon plasma coagulation in a patient with massive cachexia and esophageal obstruction: a case report and review of literatureF Geisler
Gap, Department of Internal Medicine II, Technical University of Munich, Munchen, Germany
Dis Esophagus 15:180-5. 2002.... - Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflexB Yuece
Department of Internal Medicine II and Institute of Surgical Research, Ludwig Maximilians University Munich, Munich, Germany
Neurogastroenterol Motil 19:744-53. 2007..Our data strongly suggest a physiological involvement of the CB-1 receptor in the regulation of small intestinal motility. Therefore, CB1 receptors are a promising target for the treatment of motility disorders... - Autoantibody profile in progressive systemic sclerosis as markers for esophageal involvementR Gonzalez
II. Medizinische und Poliklinik Klinikum rechts der Isar, Technical University, Munich, Germany
J Clin Gastroenterol 32:123-7. 2001..An involvement of esophageal motility was found in 100% of the patients with ACA. Our results suggest that esophageal involvement is more pronounced in patients with PSS with ACA as compared with patients with only Sc170 or ANA... - Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestineM Storr
Department of Internal Medicine II and Institute for Surgical Research, Ludwig Maximilian University of Munich, Germany
Digestion 70:257-64. 2004..STW 5 is a phytotherapeutic agent consisting of a fixed mixture of 9 individual plant extracts. The electrophysiological mechanisms of action of STW 5 remain obscure... - CB1 and TRPV1 receptors mediate protective effects on colonic electrophysiological properties in miceA Sibaev
Department of Internal Medicine II and Institute of Surgical Research, Ludwig Maximilians University Munich, Marchioninistr 15, 81377, Munich, Germany
J Mol Med (Berl) 84:513-20. 2006..In mutants, these electrophysiological changes display different patterns, suggesting the lack of protective properties for neuromuscular interactions and membrane stability... - Pharmacologic management and treatment of gastroesophageal reflux diseaseM Storr
Department of Internal Medicine II Standort Grosshadern, Ludwig Maximilians University, Munich, Germany
Dis Esophagus 17:197-204. 2004..This article gives an overview of the pharmacological management of GERD and focuses on the differential therapy of endoscopy-negative GERD, GERD with esophagitis and maintenance therapy...