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Genomes and Genes | Sonja StänderSummaryCountry: Germany Publications
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Publications
Medical treatment of pruritusSonja Ständer
Competence Center Chronic Pruritus, Department of Dermatology, University Hospital Munster, Germany
Expert Opin Emerg Drugs 17:335-45. 2012..Promising candidates are next to neurokinin receptor 1 antagonists, antagonists against the histamine 4 receptor, nerve growth factor receptor or gastrin-releasing peptide receptor...
[Assessment of pruritus - current standards and implications for clinical practice : consensus paper of the Action Group Pruritus Parameter of the International Working Group on Pruritus Research (AGP)]S Ständer
Klinik für Hautkrankheiten und Kompetenzzentrum Chronischer Pruritus, Universitatsklinikum Munster, Deutschland
Hautarzt 63:521-2, 524-31. 2012..Additional methodological developments and studies are required in order to define a robust set of instruments for measuring pruritus in daily practice and in clinical studies...
Chronic pruritusS Ständer
Department of Dermatology, Competence Center Chronic Pruritus, University Hospital Munster, Munster, Germany
G Ital Dermatol Venereol 147:161-9. 2012..The antipruritic therapy is still based on symptomatic regimens and target-specific therapies urgently needed...
[No recognizable dermatosis. What is the etiology of chronic pruritus?]Sonja Ständer
Klin Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
MMW Fortschr Med 150:40-1. 2008
[Diagnostic and therapeutic procedures in chronic pruritus]Sonja Ständer
Abteilung Klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
J Dtsch Dermatol Ges 4:350-70. 2006
[Rational symptomatic therapy for chronic pruritus]S Ständer
Abteilung für klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 57:403-10. 2006..The most effective approach is to gradually combine therapies, always considering both the medical and financial impacts...
[Clinical classification of chronic pruritus. Interdisciplinary consensus proposal for a diagnostic algorithm]S Ständer
Abteilung für klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 57:390-4. 2006..The proposed clinical classification is oriented at the clinical appearance of the patients and differentiates between disorders with or without primary or secondary skin lesions...
[Pruritus]S Ständer
Abteilung Klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 57:378. 2006
[Chronic itching. Etiology and therapeutic measures]Sonja Ständer
Abteilung für klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Med Monatsschr Pharm 29:51-5. 2006
Pathogenesis of pruritusSonja Ständer
Competence Center Chronic Pruritus, Department of Dermatology, University of Munster, Germany
J Dtsch Dermatol Ges 9:456-63. 2011..For example, kappa-opioid receptor agonists and neurokinin-1 antagonists have been found to relieve chronic pruritus...
Itch in atopic dermatitis - pathophysiology and treatmentSonja Ständer
Department of Dermatology, Competence Center Pruritus, University of Munster, Germany
Acta Dermatovenerol Croat 18:289-96. 2010..The new findings suggest that target-specific therapies are most likely to control atopic dermatitis itch. To date, only few therapies are available and controlled studies are pending...
Chronic itch and pain--similarities and differencesSonja Ständer
Clinical Neurodermatology, Department of Dermatology, University of Munster, Von Esmarch Strasse 58, D 48149 Munster, Germany
Eur J Pain 10:473-8. 2006..Finally, itch and pain exhibit corresponding patterns of central sensitization. The knowledge of antagonistic interaction, but also of similar sensitization processes has major implication for antipruritic therapeutic approaches...
[Topical cannabinoid agonists. An effective new possibility for treating chronic pruritus]S Ständer
Abteilung für klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster, Von Esmarchstrasse 58, 48149 Munster
Hautarzt 57:801-7. 2006..Recently, the expression of cannabinoid receptors on cutaneous sensory nerve fibers was described, so cannabinoid agonists seem a rational therapeutic option for pruritus...
Prevalence of chronic pruritus in Germany: results of a cross-sectional study in a sample working population of 11,730S Ständer
Department of Dermatology, Competence Center Pruritus, University Hospital Munster, Munster, Germany
Dermatology 221:229-35. 2010..Pruritus is a frequent symptom in many diseases; its prevalence in German adults is unknown...
Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skinS Ständer
Department of Dermatology and Boltzmann Institute for Immuno and Cell Biology of the Skin, University of Munster, Von Esmarch Strasse 58, Munster, Germany
Br J Dermatol 156:1020-6. 2007..The only clinically relevant side-effect reported is transient application site burning and stinging itch at the beginning of topical therapy...
Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategySonja Ständer
Department of Dermatology, Neurodermatology and Competence Center Pruritus, University of Munster, Munster, Germany
PLoS ONE 5:e10968. 2010..Substance P (SP) is a major mediator of pruritus. As it binds to the neurokinin receptor 1 (NKR1), we evaluated if the application of a NKR1 antagonist would significantly decrease chronic pruritus...
[Chronic pruritus: principals of diagnostics and therapy]S Ständer
Klinik und Poliklinik für Hautkrankheiten, Klinische Neurodermatologie, Universitatsklinikum Munster, Von Esmarchstrasse 58, 48149 Munster, Germany
Hautarzt 58:627-36; quiz 637. 2007..Next to conventional therapies such as antihistamines and corticosteroids, central effective substances can be applied preventing pruritus sensation on spinal or cerebral level...
Clinical classification of itch: a position paper of the International Forum for the Study of ItchSonja Ständer
Clinical Neurodermatology, Department of Dermatology, University of Munster, Von Esmarch Strasse 58, Munster, Germany
Acta Derm Venereol 87:291-4. 2007..It is intended to serve as a diagnostic route for better evaluation of patients with chronic pruritus and aims to improve patients' care...
Neurophysiological and neurochemical basis of modern pruritus treatmentSonja Ständer
Clinical Neurodermatology, Department of Dermatology, University of Muenster, Muenster, Germany
Exp Dermatol 17:161-9. 2008..In summary, these recent developments show that highlighting the basis of pruritus offers modern neurophysiological and neurochemical therapeutic models and the possibility to treat patients with refractory itching of different origin...
Putative neuronal mechanisms of sensitive skinSonja Ständer
Department of Dermatology, University of Munster, Munster, Germany
Exp Dermatol 18:417-23. 2009..Furthermore, we discuss the role of neurotrophins and the influence of stress on sensitive skin...
Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgiaNgoc Quan Phan
Competence Center for the Diagnosis and Treatment of Pruritus, Clinic and Polyclinic for Skin Diseases, University Hospital of Munster, Germany
J Dtsch Dermatol Ges 8:88-91. 2010..These nerves express cannabinoid receptors which exert a role in modulation of nociceptive symptoms. Therefore, topical therapy with cannabinoid receptor agonist seems likely to suppress local burning pain...
[Erythrokeratodermia variabilis (EKV)--a disorder due to altered epidermal expression of gap junction proteins]Sonja Ständer
Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
J Dtsch Dermatol Ges 3:354-8. 2005..The mutation in connexin 31 is regarded therefore as causal for the clinical picture of the EKV. The unique upregulation of connexin 43 may occur as a consequence of the Cx31 mutation and temporarily compensate for this defect...
[Pruritus--pathophysiology, clinical features and therapy--an overview]Sonja Ständer
Universitäts Hautklinik Münster
J Dtsch Dermatol Ges 1:105-18. 2003..These observations led to the development of new therapeutic modalities. This paper gives an overview of itch pathophysiology, clinical types and therapies...
Localization of mu-opioid receptor 1A on sensory nerve fibers in human skinSonja Ständer
Department of Dermatology, University of Munster, Munster, Germany
Regul Pept 110:75-83. 2002..Together, our findings contribute to the understanding of the high antipruritic potency of opioid receptor antagonists in various skin and systemic diseases...
Hydroxyethyl starch does not cross the blood-brain or the placental barrier but the perineurium of peripheral nerves in infused animalsS Ständer
Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Germany
Cell Tissue Res 310:279-87. 2002..No HES storage was found in the central nervous system. Our findings clearly demonstrate that storage of HES is detectable only in small peripheral nerves, suggesting a cutaneous origin of the HES-induced pruritus...
Expression of melanocortin-1 receptor in normal, malformed and neoplastic skin glands and hair folliclesSonja Ständer
Department of Dermatology, Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Munster, Germany
Exp Dermatol 11:42-51. 2002..In conclusion, preserved MC-1R expression in adnexal epithelia suggests a functional role of proopiomelanocortin (POMC) in various malformations and neoplasms of the skin...
Pathophysiology of pruritus in atopic dermatitis: an overviewSonja Ständer
Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Munster, Germany
Exp Dermatol 11:12-24. 2002..This review highlights the recent knowledge of different mechanisms which may be involved in regulating pruritus in patients with AD potentially leading to new therapeutic applications for the treatment of itch in AD...
[Wax model collection of the Department of Dermatology, University of Münster]S Ständer
Universitäts Hautklinik, Westfälischen Wilhelms Universität Münster
Hautarzt 52:662-6. 2001..The Department of Dermatology in Münster is in the possession of 121 wax models, which are presented in this article...
[Familial dyskeratotic comedones. A rare entity]S Ständer
Universitäts Hautklinik der Westfälischen Wilhelms Universität Münster
Hautarzt 52:533-6. 2001..Familial dyskeratotic comedones are generally refractory to any therapy. We report on two sisters with familial dyskeratotic comedones successfully treated by CO2-laser therapy...
Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term studyS Ständer
Department of Dermatology, University of Munster, Germany
Cell Tissue Res 304:261-9. 2001..The condensation and final dissolution of the vacuoles may either indicate the release and subsequent redistribution of HES into the circulation or lysosomal degradation...
[Control of section margins without any gaps in paraffin sections of melanoma of the face]S Ständer
Universitäts Hautklinik der Westfälischen Wilhelms Universität Münster
Hautarzt 51:826-32. 2000..Malignant melanomas on sun-exposed skin are often poorly circumscribed and thus recur frequently. The aim of our clinical trial was to compare conventional to a modified micrographic surgery of primary melanoma...
[Antipruritic effects of pimecrolimus and tacrolimus]S Ständer
Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 54:413-7. 2003..Moreover, the antipruritic potency may be related to a direct effect on nerve fibers leading to suppression of itch mediated by unknown mechanisms...
[Squamous epithelial carcinomas of the face with neurotropic growth]S Ständer
Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 54:1087-94. 2003..Perineural outgrowth into cerebral nerves may result in severe pain or neurological disturbances. In addition, these carcinomas more often recur or metastasize and therefore are associated with a poor prognosis...
Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skinSonja Ständer
Department of Dermatology, University Hospital Munster, Germany
J Dermatol Sci 38:177-88. 2005..Cannabinoid receptors mediate the psychopharmacological action of marijuana and have been localized in the central and peripheral nervous system as well as on cells of the immune system...
Reduced intraepidermal nerve fibre density in lesional and nonlesional prurigo nodularis skin as a potential sign of subclinical cutaneous neuropathyB Schuhknecht
Departments of Dermatology Neurology, Competence Center Chronic Pruritus, University Hospital Munster, D 48149 Munster, Germany
Br J Dermatol 165:85-91. 2011..Prurigo nodularis (PN) is a highly pruritic condition characterized by multiple hyperkeratotic nodules. Previous immunohistochemical studies demonstrated increased numbers of dermal nerve fibres...
[Pruritus--symptom of both skin and systemic diseases]Sonja Ständer
Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
MMW Fortschr Med 147:44-6. 2005..Treatment is directed initially to the underlying illness, and both topical and systemic antipruritic medications are available as flanking measures...
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is expressed in normal skin and cutaneous inflammatory diseases, but not in chronically UV-exposed skin and non-melanoma skin cancerSonja Ständer
Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University Clinics Münster, Munster, Germany
Am J Dermatopathol 27:116-21. 2005..Down-regulation of TRAIL might represent another example of a natural protection mechanism that is eliminated by chronic UV exposure...
Neurophysiology of pruritus: cutaneous elicitation of itchSonja Ständer
Department of Dermatology, University of Munster, Munster, Germany
Arch Dermatol 139:1463-70. 2003..This review focuses on the peripheral generation of itch, including neurotransmitters, neuropeptides, and inflammatory mediators...
Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structuresSonja Ständer
Department of Dermatology, University of Munster, Muenster, Germany
Exp Dermatol 13:129-39. 2004..After cessation of capsaicin therapy, neuropeptides re-accumulated in skin nerves. In conclusion, VR1 is widely distributed in the skin, suggesting a major role for this receptor, e.g. in nociception and neurogenic inflammation...
Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormoneMarkus Bohm
Department of Dermatology and the Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, 48149 Munster, Germany
J Biol Chem 279:6959-66. 2004..Melanocortins such as alpha-MSH may therefore represent a novel class of modulators with potential usefulness for the treatment of fibrotic disorders...
Chronic pruritus: targets, mechanisms and future therapiesEsther Pogatzki-Zahn
Department of Anesthesiology and Intensive Care, Competence Center for the Diagnostic and Therapy of Chronic Pruritus, University of Munster, Munster, Germany
Drug News Perspect 21:541-51. 2008..The present review aims to provide an overview of current neurophysiological and neurochemical therapeutic models in chronic pruritus...
Treatment of chronic pruritus with the selective serotonin re-uptake inhibitors paroxetine and fluvoxamine: results of an open-labelled, two-arm proof-of-concept studySonja Ständer
Department of Dermatology, Clinical Neurodermatology, University of Munster, Munster, Germany
Acta Derm Venereol 89:45-51. 2009..This should be confirmed in future double-blind studies...
Prurigo nodularis: systematic analysis of 58 histological criteria in 136 patientsNils Weigelt
Department of Dermatology, Neurodermatology and Competence Center Pruritus, University of Munster, Munster, Germany
J Cutan Pathol 37:578-86. 2010..To date, there has been no systematic investigation of the detailed histological features of prurigo nodularis (PN) in a large cohort of patients...
Underlying diseases and co-factors in patients with severe chronic pruritus: a 3-year retrospective studyFranz Sommer
Clinical Neurodermatology, Department of Dermatology, University of Munster, Germany
Acta Derm Venereol 87:510-6. 2007..In conclusion, patients with chronic pruritus present a inhomgeneous collective with different underlying diseases, including malignancy, necessitating thorough investigation...
Brachioradial pruritus as a result of cervical spine pathology: the results of a magnetic resonance tomography studyMartin Marziniak
Department of Neurology, University Hospital Munster, Munster, Germany
J Am Acad Dermatol 65:756-62. 2011..Brachioradial pruritus (BRP) describes a rare form of itching occurring at the dorsolateral part of the forearms. Recent case reports suggest that BRP may be attributed to cervical lesions or spine neoplasms...
Role of matriptase and proteinase-activated receptor-2 in nonmelanoma skin cancerGeorgeta Bocheva
University of Munster, Munster, Germany
J Invest Dermatol 129:1816-23. 2009..In conclusion, our results suggest that PAR(2) is a substrate for matriptase in human skin in vivo. Deregulation of these proteins delineates SCC progression...
Antipruritic treatment with systemic μ-opioid receptor antagonists: a reviewNgoc Quan Phan
Competence Center Pruritus, Department of Dermatology, University Hospital Munster, Munster, Germany
J Am Acad Dermatol 63:680-8. 2010..We will also evaluate recommendations for the use of MORA in daily medical practice...
Aquagenic pruritus: associated diseases and clinical pruritus characteristicsTina Heitkemper
Neurodermatology and Competence Center Pruritus, Clinic and Polyclinic for Dermatology, University Hospital of Munster, Germany
J Dtsch Dermatol Ges 8:797-804. 2010..This retrospective study aimed to determine the frequency and pruritus-specific parameter of systemic diseases in a series of patients...
Proteinase-activated receptor-2 (PAR2): a tumor suppressor in skin carcinogenesisAnke Rattenholl
Department of Dermatology and Interdisciplinary Center for Clinical Research IZKF Münster, University of Munster, Munster, Germany
J Invest Dermatol 127:2245-52. 2007..Thus, our results provide early experimental evidence for a tumor-protective role of PAR(2)...
Treatment of pustular psoriasis with infliximabCarsten Weishaupt
Clinic and Polyclinic for Skin Diseases, Munster University Hospital, Germany
J Dtsch Dermatol Ges 5:397-9. 2007..We suggest that infliximab is a therapeutic option for severe therapy-resistant pustular psoriasis because a single well-tolerated dose significantly ameliorates the patient's condition...
Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situMarkus Bohm
Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Munster, Germany
J Invest Dermatol 118:533-9. 2002..By modulating interleukin-8 secretion, alpha-melanocyte-stimulating hormone may act as a modulator of inflammatory responses in the pilosebaceous unit...
IL-18 reduces ultraviolet radiation-induced DNA damage and thereby affects photoimmunosuppressionAgatha Schwarz
Department of Dermatology, University Kiel, Kiel, Germany
J Immunol 176:2896-901. 2006..Though being primarily a proinflammatory cytokine through this capacity, IL-18 can also foster an immune response that is suppressed by UV radiation...
Cholestatic pruritus: a retrospective analysis on clinical characteristics and treatment responseMario Huesmann
Competence Center Chronic Pruritus and Department of Dermatology, University Hospital Munster, Germany Institute for Medical Informatics and Biomathematics, University Hospital Munster, Germany Medical Clinic 1, University of Erlangen, Germany
J Dtsch Dermatol Ges 11:158-68. 2013..Other underlying diseases were represented to a lower extent in the total study population. Overall, the collected clinical parameters in each group were comparable. Thus, it was difficult to draw conclusions on the pathogenesis...
CIS-based registration of quality of life in a single source approachFleur Fritz
Institute of Medical Informatics, University Munster, Domagkstrasse 9, 48149 Munster, Germany
BMC Med Inform Decis Mak 11:26. 2011..We therefore aimed at developing an efficient method to integrate quality of life information into the clinical information system (CIS) and thus make it available for clinical care and secondary use...
Enhanced contact hypersensitivity and antiviral immune responses in vivo by keratinocyte-targeted overexpression of IL-15Karin Loser
Department of Dermatology, University of Munster, Munster, Germany
Eur J Immunol 34:2022-31. 2004..Together, our results show that overexpression of IL-15 in the epidermis enhances both innate and adaptive cutaneous immunity...
Antipruritic effect of cyclosporine microemulsion in prurigo nodularis: results of a case seriesDorothee Siepmann
Clinical Neurodermatology, Department of Dermatology, University of Munster, Munster, Germany
J Dtsch Dermatol Ges 6:941-6. 2008..The aim of this investigation was to assess the antipruritic efficiency of cyclosporine ME in therapy of prurigo nodularis...
[Antipruritic efficacy of a high-dosage antihistamine therapy. Results of a retrospectively analysed case series]S Schulz
Kompetenzzentrum Pruritus, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
Hautarzt 60:564-8. 2009..The aim of this investigation was to describe the efficacy and safety of high-dosage antihistamine treatment in patients with chronic pruritus of different origin...
Psychological factors in prurigo nodularis in comparison with psoriasis vulgaris: results of a case-control studyG Schneider
Department of Psychosomatics and Psychotherapy, University of Muenster, Germany
Br J Dermatol 154:61-6. 2006..Whether these issues are specific for PN or are also common in other chronic skin diseases, e.g. psoriasis, has not been investigated until now...
Psychosomatic cofactors and psychiatric comorbidity in patients with chronic itchG Schneider
Department of Psychosomatics and Psychotherapy, University of Muenster, Muenster, Germany
Clin Exp Dermatol 31:762-7. 2006..While psychosomatic factors may be involved in eliciting as well as coping with chronic itch, psychiatric comorbidity often goes unrecognized in dermatological patients...
Revised Cutaneous Lupus Erythematosus Disease Area and Severity Index (RCLASI): a modified outcome instrument for cutaneous lupus erythematosusA Kuhn
Department of Dermatology, University of Munster, Von Esmarch Strasse 58, D 48149 Munster, Germany
Br J Dermatol 163:83-92. 2010..However, the CLASI does not give an accurate assessment of the severity in all disease subtypes...
Assessment of pruritus intensity: prospective study on validity and reliability of the visual analogue scale, numerical rating scale and verbal rating scale in 471 patients with chronic pruritusNgoc Quan Phan
Competence Center for Chronic Pruritus, Department of Dermatology, University Hospital, Munster, Germany
Acta Derm Venereol 92:502-7. 2012..In conclusion, high reliability and concurrent validity was found for VAS, NRS and VRS. On re-test, higher correlation and less missing values were observed. A training session before starting a clinical trial is recommended...
Modulation of cutaneous inflammation by angiotensin-converting enzymeThomas E Scholzen
Ludwig Boltzmann Institute of Cell Biology and Immunobiology of the Skin, University of Munster, Munster, Germany
J Immunol 170:3866-73. 2003....
Keratoacanthoma with perineural invasion: an indicator for aggressive behavior?Yasmin Basoglu
Department of Dermatology, University of Munster, Munster, Germany
J Dtsch Dermatol Ges 6:952-5. 2008..Our case suggests that perineural invasion may be an indicator for aggressive growth of head-and-neck KAs so that histologically-controlled excision is recommended...
Notalgia Paraesthetica: A Descriptive Two-cohort Study of 65 Patients from Brazil and GermanyTimo Huesmann
Competence Center Chronic Pruritus, Department of Dermatology, University Hospital Munster, Munster, Germany
Acta Derm Venereol 92:535-40. 2012..7% of the involved areas. The significant reduction in intraepidermal nerve fiber density suggests that damage to the peripheral nerves is a more important aetiological factor than spinal changes in notalgia paraesthetica...
Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: a literature reviewNgoc Quan Phan
Competence Center for Chronic Pruritus, Department of Dermatology, University Hospital, Munster, Germany
Acta Derm Venereol 92:555-60. 2012..The aim of this review is to provide an overview of the promising role of kappa- opioid receptors and their agonist in the pathophysiology and treatment of pruritus...
Significant differences in central imaging of histamine-induced itch between atopic dermatitis and healthy subjectsGudrun Schneider
Department of Psychosomatics and Psychotherapy, University of Munster, Domagkstr 22, D 48149 Munster, Germany
Eur J Pain 12:834-41. 2008....
Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repairAgatha Schwarz
Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, Department of Dermatology, , Von-Esmarchstrasse 58, , Germany
Nat Cell Biol 4:26-31. 2002..Our results show that cytokines can protect cells from apoptosis induced by DNA-damaging UV radiation by inducing DNA repair, and that nucleotide-excision repair can be manipulated by cytokines...
Modern aspects of cutaneous neurogenic inflammationMartin Steinhoff
Department of Dermatology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Heidelberg, Germany
Arch Dermatol 139:1479-88. 2003..Understanding the mechanisms and the factors controlling neuromediators and their receptors and degrading enzymes will lead to the identification of novel therapeutic targets for the treatment of cutaneous diseases...
