- Towards a general procedure for sequencing single DNA moleculesJ Stephan
Max Planck Institut fur biophysikalische Chemie, Abteilung Biochemische Kinetik, Am Fassberg 2, D 37077 Gottingen, Germany
J Biotechnol 86:255-67. 2001..Furthermore, the mathematical processing of the obtained raw data is described. A first complete experimental cycle is shown, combining all preparatory steps which are necessary for single molecule sequencing in microstructures...
- Highly efficient single molecule detection in microstructuresK Dörre
Max Planck Institut fur biophysikalische Chemie, Abteilung Biochemische Kinetik, Am Fassberg 11, D 37077 Gottingen, Germany
J Biotechnol 86:225-36. 2001..From these data the signal-to-noise ratio in microstructures is evaluated as well as the overall detection efficiency. So far, detection efficiencies of single molecule events of up to 60% have been shown in microstructures...