Arnulf Stenzl

Summary

Country: Germany

Publications

  1. ncbi request reprint Introducing a new sealant applicator for easy, safe, and quick closure of a mini-percutaneous nephrolitholapaxy access tract
    Udo Nagele
    Department of Urology, University of Tubingen, Tubingen, Germany
    J Endourol 21:393-6. 2007
  2. ncbi request reprint Immunoreactivity of p63 in monolayered and in vitro stratified human urothelial cell cultures compared with native urothelial tissue
    Gerhard Feil
    Department of Urology, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    Eur Urol 53:1066-72. 2008
  3. doi request reprint An update on the medical therapy of advanced metastatic renal cell carcinoma
    Stephan Kruck
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Scand J Urol Nephrol 42:501-6. 2008
  4. ncbi request reprint Decreased expression of galectin-3 predicts tumour recurrence in pTa bladder cancer
    Mario Wolfgang Kramer
    Department of Urology, Eberhard Karls University, D 72076 Tubingen, Germany
    Oncol Rep 20:1403-8. 2008
  5. pmc Fibronectin 1 mRNA expression correlates with advanced disease in renal cancer
    Sandra Waalkes
    Department of Urology, Hannover Medical School, Germany
    BMC Cancer 10:503. 2010
  6. pmc Reduced mRNA expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer
    Hossein Tezval
    Department of Urology and Urological Oncology, Hannover Medical School, Hannover, Germany
    BMC Cancer 13:199. 2013
  7. ncbi request reprint [Treatment of muscle-invasive and metastatic bladder cancer: update of the EAU guidelines]
    A Stenzl
    Servicio de Urologia, Universidad Eberhard KarlsTuebingen, Alemania
    Actas Urol Esp 36:449-60. 2012
  8. pmc Quantification of HLA class I molecules on renal cell carcinoma using Edman degradation
    Juliane S Stickel
    Department of Immunology, Institute for Cell Biology, University of Tubingen, Germany
    BMC Urol 11:1. 2011
  9. pmc Intensity modulated radiotherapy for high risk prostate cancer based on sentinel node SPECT imaging for target volume definition
    Ute Ganswindt
    Department of Radiation Oncology, University of Tubingen, Tubingen, Germany
    BMC Cancer 5:91. 2005
  10. ncbi request reprint Radical cystectomy with orthotopic neobladder for invasive bladder cancer: a critical analysis of long term oncological, functional and quality of life results
    Arnulf Stenzl
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Int Braz J Urol 36:537-47. 2010

Detail Information

Publications93

  1. ncbi request reprint Introducing a new sealant applicator for easy, safe, and quick closure of a mini-percutaneous nephrolitholapaxy access tract
    Udo Nagele
    Department of Urology, University of Tubingen, Tubingen, Germany
    J Endourol 21:393-6. 2007
    ..To achieve better hemostasis after mini-percutaneous nephrolitholapaxy (mini-PCNL), we developed a new application device that can be used to close the renal-access tract with gelatin matrix hemostatic sealant (GMHS)...
  2. ncbi request reprint Immunoreactivity of p63 in monolayered and in vitro stratified human urothelial cell cultures compared with native urothelial tissue
    Gerhard Feil
    Department of Urology, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    Eur Urol 53:1066-72. 2008
    ..To investigate the immunoreactivity of p63 in monolayered and stratified human urothelial cell cultures and in normal urothelial tissues to assess the differentiation status of in vitro stratified urothelial constructs...
  3. doi request reprint An update on the medical therapy of advanced metastatic renal cell carcinoma
    Stephan Kruck
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Scand J Urol Nephrol 42:501-6. 2008
    ..This review discusses the effectiveness of the most frequently used substances for systemically progressive RCC in consideration of the currently available clinical data...
  4. ncbi request reprint Decreased expression of galectin-3 predicts tumour recurrence in pTa bladder cancer
    Mario Wolfgang Kramer
    Department of Urology, Eberhard Karls University, D 72076 Tubingen, Germany
    Oncol Rep 20:1403-8. 2008
    ....
  5. pmc Fibronectin 1 mRNA expression correlates with advanced disease in renal cancer
    Sandra Waalkes
    Department of Urology, Hannover Medical School, Germany
    BMC Cancer 10:503. 2010
    ..The aim of this study was to elucidate the role of FN1 in development of renal cell cancer (RCC) and to determine a prognostic relevance for optimal clinical management...
  6. pmc Reduced mRNA expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer
    Hossein Tezval
    Department of Urology and Urological Oncology, Hannover Medical School, Hannover, Germany
    BMC Cancer 13:199. 2013
    ..The objective of our study was to assess the expression of the CRHBP mRNA and protein in renal cancer...
  7. ncbi request reprint [Treatment of muscle-invasive and metastatic bladder cancer: update of the EAU guidelines]
    A Stenzl
    Servicio de Urologia, Universidad Eberhard KarlsTuebingen, Alemania
    Actas Urol Esp 36:449-60. 2012
    ..New data regarding treatment of muscle-invasive and metastatic bladder cancer (MiM-BC) has emerged and led to an update of the European Association of Urology (EAU) guidelines for MiM-BC...
  8. pmc Quantification of HLA class I molecules on renal cell carcinoma using Edman degradation
    Juliane S Stickel
    Department of Immunology, Institute for Cell Biology, University of Tubingen, Germany
    BMC Urol 11:1. 2011
    ..HLA loss or down-regulation have often been reported and might interfere with immunotherapeutic approaches aimed at the recognition of HLA-presented peptides...
  9. pmc Intensity modulated radiotherapy for high risk prostate cancer based on sentinel node SPECT imaging for target volume definition
    Ute Ganswindt
    Department of Radiation Oncology, University of Tubingen, Tubingen, Germany
    BMC Cancer 5:91. 2005
    ..To overcome this limitation, we tested the feasibility of an intensity modulated radiation therapy (IMRT) protocol, taking under consideration the individual pelvic sentinel node drainage pattern by SPECT functional imaging...
  10. ncbi request reprint Radical cystectomy with orthotopic neobladder for invasive bladder cancer: a critical analysis of long term oncological, functional and quality of life results
    Arnulf Stenzl
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Int Braz J Urol 36:537-47. 2010
    ..Analyze current knowledge and practice regarding tumor-related cystectomy with subsequent orthotopic neobladder both in male and female patients...
  11. ncbi request reprint Can we still afford bladder cancer?
    Arnulf Stenzl
    Department of Urology, Eberhard Karls University Tuebingen, Tuebingen, Germany
    Curr Opin Urol 18:488-92. 2008
    ..Costs for follow-up (excluding costs for reinterventions) compared with transurethral resection and cystectomy account for a considerably lower portion of the overall costs...
  12. ncbi request reprint The updated EAU guidelines on muscle-invasive and metastatic bladder cancer
    Arnulf Stenzl
    Department of Urology, Eberhard Karls University Tuebingen, Tuebingen, Germany
    Eur Urol 55:815-25. 2009
    ..New data regarding diagnosis and treatment of muscle-invasive and metastatic bladder cancer (MiM-BC) has emerged and led to an update of the European Association of Urology (EAU) guidelines for MiM-BC...
  13. doi request reprint Detection and clinical outcome of urinary bladder cancer with 5-aminolevulinic acid-induced fluorescence cystoscopy : A multicenter randomized, double-blind, placebo-controlled trial
    Arnulf Stenzl
    Medical Center of Eberhard Karls University, Department of Urology, Tubingen, Germany
    Cancer 117:938-47. 2011
    ..The medical community lacks results from prospective controlled multicenter studies of the diagnostic efficacy of 5-aminolevulinic acid (5-ALA) cystoscopy on tumor recurrence in patients with superficial bladder tumors...
  14. doi request reprint Treatment of muscle-invasive and metastatic bladder cancer: update of the EAU guidelines
    Arnulf Stenzl
    Department of Urology, Eberhard Karls University Tuebingen, Tuebingen, Germany
    Eur Urol 59:1009-18. 2011
    ..New data regarding treatment of muscle-invasive and metastatic bladder cancer (MiM-BC) has emerged and led to an update of the European Association of Urology (EAU) guidelines for MiM-BC...
  15. ncbi request reprint [Photodynamic diagnostics in the urinary tract. Consensus paper of the Working Group for Oncology of the German Society for Urology]
    A Stenzl
    Universitatsklinik fur Urologie, Eberhard Karls Universitat Tubingen, Hoppe Seyler Str 3, 72076, Tubingen, Germany
    Urologe A 47:982-7. 2008
    ..A consensus with regards to the indications, contraindications, technique, pre-clinical data, comparison of HAL and 5-ALA, current results, costs and follow-up was reached and are presented in this paper...
  16. doi request reprint Activation of PI3K is associated with reduced survival in renal cell carcinoma
    Axel S Merseburger
    Department of Urology, Eberhard Karls University Tubingen, Tubingen, Germany
    Urol Int 80:372-7. 2008
    ..PTEN dephosphorylates the liquid product of PI3K...
  17. doi request reprint Individual risk assessment in bladder cancer patients based on a multi-marker panel
    Tilman Todenhöfer
    Department of Urology, University Hospital Tuebingen, Tuebingen, Germany
    J Cancer Res Clin Oncol 139:49-56. 2013
    ..To investigate whether a combined application of urine cytology (CYT) and molecular markers for bladder cancer (BC) can predict tumor aggressiveness...
  18. ncbi request reprint Altered expression of Akt signaling pathway parameters in prostate needle biopsies derived from benign, adjacent and cancerous tissue
    Sandra Waalkes
    Department of Urology, Hannover University Medical School, Hannover, Germany
    Oncol Rep 23:1257-60. 2010
    ..Molecular markers might further augment the histopathological diagnosis suggesting the need for earlier repeated prostate biopsy in case of microscopic malignancy...
  19. doi request reprint Novel multi-peptide vaccination in Hla-A2+ hormone sensitive patients with biochemical relapse of prostate cancer
    Susan Feyerabend
    Department of Urology, University of Tubingen, Germany
    Prostate 69:917-27. 2009
    ..A phase I/II trial was conducted to assess feasibility and tolerability of tumor associated antigen peptide vaccination in hormone sensitive prostate carcinoma (PC) patients with biochemical recurrence after primary surgical treatment...
  20. ncbi request reprint Optimized coverage of high-risk adjuvant lymph node areas in prostate cancer using a sentinel node-based, intensity-modulated radiation therapy technique
    Ute Ganswindt
    Department of Radiation Oncology, University of Tuebingen, Tuebingen, Germany
    Int J Radiat Oncol Biol Phys 67:347-55. 2007
    ..To account for the highly individual lymphatic drainage pattern we tested an intensity-modulated radiation therapy (IMRT) approach based on the determination of pelvic sentinel lymph nodes (SN)...
  21. ncbi request reprint Bilateral laparoscopic postchemotherapy retroperitoneal lymph-node dissection in nonseminomatous germ cell tumors--a comparison to template dissection
    Stefan Aufderklamm
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    J Endourol 27:856-61. 2013
    ..Ipsilateral template dissection is a compromise between morbidity and oncological efficacy. Here, we compare ipsilateral with primary bilateral laparoscopic (L)-RPLND after chemotherapy in terms of morbidity and oncological safety...
  22. doi request reprint Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?
    Tilman Todenhöfer
    Department of Urology, University Hospital Tubingen, Tubingen, Germany
    World J Urol 31:345-50. 2013
    ..The exact role of this pathway in prostate cancer (PC) has not been identified yet. Herein, we evaluate the expression of farnesyl pyrophosphate synthase (FPPS), the key enzyme of the mevalonate pathway, in PC...
  23. doi request reprint Anterior urethral reconstruction using the circular fasciocutaneous flap technique: long-term follow-up
    Christian Schwentner
    Department of Urology, Eberhard Karls University Tuebingen, University Hospital Tuebingen, Tuebingen, Germany
    World J Urol 29:115-20. 2011
    ..The circular fasciocutaneous skin flap technique (FCF) yields excellent short-term results for complex anterior urethral reconstruction. We performed an observational retrospective and descriptive study to report our long-term experience...
  24. ncbi request reprint Topographical sensitivity and specificity of endorectal coil magnetic resonance imaging for prostate cancer detection
    Daniela Colleselli
    Department of Urology, Eberhard Karls University Tubingen, Tubingen, Germany
    Urol Int 84:388-94. 2010
    ..Herein, we evaluate sensitivity and specificity of EC-MRI in different regions of the prostate by comparing the acquired images to whole-mount sections of the prostate after radical prostatectomy...
  25. ncbi request reprint Accuracy of preoperative endorectal MRI in predicting extracapsular extension and influence on neurovascular bundle sparing in radical prostatectomy
    Matthias C Roethke
    Department of Radiology, Comprehensive Cancer Center CCC Tübingen, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    World J Urol 31:1111-6. 2013
    ..To evaluate the accuracy of presurgical endorectal MRI (eMRI) for local staging before radical prostatectomy (RP) and its influence on neurovascular bundle (NVB) resection during radical prostatectomy...
  26. doi request reprint Impact of different grades of microscopic hematuria on the performance of urine-based markers for the detection of urothelial carcinoma
    Tilman Todenhöfer
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Urol Oncol 31:1148-54. 2013
    ....
  27. doi request reprint Exposed proliferation antigen 210 (XPA-210) in renal cell carcinoma (RCC) and oncocytoma: clinical utility and biological implications
    Stephan Kruck
    Departments of Urology Pathology, Eberhard Karls University, Tuebingen, Germany
    BJU Int 109:634-8. 2012
    ....
  28. ncbi request reprint A newly designed amplatz sheath decreases intrapelvic irrigation pressure during mini-percutaneous nephrolitholapaxy: an in-vitro pressure-measurement and microscopic study
    Udo Nagele
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    J Endourol 21:1113-6. 2007
    ..In addition, the hydrodynamic effects of this device can be used for suction and removal of the stone fragments, in contrast to a standard Amplatz sheath...
  29. doi request reprint Initial prostate biopsy: development and internal validation of a biopsy-specific nomogram based on the prostate cancer antigen 3 assay
    Jens Hansen
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 63:201-9. 2013
    ..Urinary prostate cancer antigen 3 (PCA3) assay in combination with established clinical risk factors improves the identification of men at risk of harboring prostate cancer (PCa) at initial biopsy (IBX)...
  30. doi request reprint Laparoscopic partial nephrectomy: risk stratification according to patient and tumor characteristics
    Stephan Kruck
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    World J Urol 30:639-46. 2012
    ..We aimed to evaluate differences in complication rates and outcome stratified by risk categories, depending on patient or tumor characteristics...
  31. doi request reprint XPA-210: a new proliferation marker determines locally advanced prostate cancer and is a predictor of biochemical recurrence
    Stefan Aufderklamm
    Department of Urology, Eberhard Karls University Tubingen, Hoppe Seyler Strasse 3, Tubingen, Germany
    World J Urol 30:547-52. 2012
    ..It is of clinical significance in kidney, breast, and bladder cancer. There are no data available for XPA-210 in prostate cancer (PC). Herein, we aim to determine the clinical usefulness of XPA-210 in PC...
  32. ncbi request reprint High cytoplasmic expression of p27(Kip1) is associated with a worse cancer-specific survival in clear cell renal cell carcinoma
    Stephan Kruck
    Department of Urology Pathology, Eberhard Karls University Tuebingen, Tuebingen, Germany
    BJU Int 109:1565-70. 2012
    ..We confirmed higher p27(Kip1) expression in the nucleus and cytoplasm of RCC and correlated high cytoplasmic p27(Kip1) with an unfavourable clinic and a reduced survival...
  33. ncbi request reprint Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression
    Stephan Kruck
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Oncol Rep 23:159-63. 2010
    ..These pilot study results may contribute to the clarification of mTOR-pathway regulation processes in RCC on the way to the protein profiling-predicted targeted therapy...
  34. doi request reprint Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival
    Axel S Merseburger
    Department of Urology, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
    World J Urol 26:637-42. 2008
    ..The aim of this study was to analyze the expression of galectin-3 in clear cell renal carcinoma and to assess its prognostic significance...
  35. doi request reprint GATA5 CpG island methylation in renal cell cancer: a potential biomarker for metastasis and disease progression
    Inga Peters
    Department of Urology, Medizinische Hochschule Hannover, Hannover, Germany
    BJU Int 110:E144-52. 2012
    ....
  36. doi request reprint XPA-210: a new proliferation marker to characterize tumor biology and progression of renal cell carcinoma
    Georgios Gakis
    Department of Urology, Eberhard Karls University, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    World J Urol 29:801-6. 2011
    ..Recent lung cancer data have shown an association of XPA-210, a key peptide of thymidine kinase, with advanced disease. We thus assessed its proliferation status in primary (M0) and metastatic (M1) renal cell carcinoma (RCC)...
  37. ncbi request reprint PTEN and p27Kip1 are not downregulated in the majority of renal cell carcinomas--implications for Akt activation
    Joerg Hennenlotter
    Department of Urology, Eberhard Karls University Tuebingen, 72076 Tuebingen, Germany
    Oncol Rep 19:1141-7. 2008
    ..Furthermore, Akt activation may not result in a decreased p27Kip1, the latter being retained and overexpressed in the majority of renal cell cancers when compared with the corresponding benign renal parenchyma...
  38. doi request reprint Urethral ultrasound as a screening tool for stricture recurrence after oral mucosa graft urethroplasty
    Joerg Seibold
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Urology 78:696-700. 2011
    ..OMG urethroplasty is a standard treatment for men with recurrent urethral stricture. Because of its performance, the optimum follow-up algorithm remains controversial...
  39. ncbi request reprint Laparoscopic sentinel lymph node dissection--a novel technique for the staging of prostate cancer
    Stefan Corvin
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Eur Urol 49:280-5. 2006
    ..The aim of this study was to evaluate the suitability of laparoscopic radioisotope guided sentinel lymph node (SLN) dissection in staging of prostate carcinoma...
  40. doi request reprint Modified concept for radioisotope-guided sentinel lymph node dissection in prostate cancer
    David Schilling
    Department of Urology, Eberhard Karls University Tuebingen, Hoppe Seyler Str 3, 72076, Tuebingen, Germany
    World J Urol 28:715-20. 2010
    ..To present a modified concept for sentinel lymph node (SLN)-guided pelvic lymph node dissection in prostate cancer...
  41. ncbi request reprint Prospective assessment of histological serial sectioning of pelvic lymph nodes in prostate cancer: a cost-benefit analysis
    David Schilling
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    BJU Int 110:E166-71. 2012
    ..However, the work-load and the expenses were significantly higher compared with routine evaluation...
  42. ncbi request reprint Membranous expression and prognostic implications of epidermal growth factor receptor protein in human renal cell cancer
    Axel S Merseburger
    Department of Urology, Eberhard Karls University Tuebingen, Hoppe Seyler Str 3, 72076, Tuebingen, Germany
    Anticancer Res 25:1901-7. 2005
    ..Therefore, the aim of the present study was to determine EGFR expression in clear cell renal cell carcinomas (RCC) to evaluate its prognostic relevance for the clinical course of the disease...
  43. doi request reprint Upper urinary tract laparoendoscopic single-site surgery based on a novel cost-effective reusable platform
    Christian Schwentner
    Department of Urology, Eberhard Karls University Tuebingen, Germany
    J Endourol 27:202-7. 2013
    ..Besides technical issues, cost is one of the main limiting factors for their widespread use. We present our experience with LESS surgery for kidney pathologies using the first completely reusable LESS platform...
  44. ncbi request reprint Differential Akt signalling in non-seminomatous testicular germ cell tumors
    Joerg Hennenlotter
    Department of Urology, Eberhard Karls University, Tuebingen, Hoppe Seyler Str 3, 72076 Tuebingen, Germany
    Anticancer Res 31:3783-8. 2011
    ....
  45. doi request reprint The learning curve in minimally invasive percutaneous nephrolitholapaxy: a 1-year retrospective evaluation of a novice and an expert
    David Schilling
    Department of Urology, University Hospital Tuebingen, Hoppe Seyler Str 3, 72076, Tubingen, Germany
    World J Urol 29:749-53. 2011
    ..The aim of this study was to compare a novice surgeon with an expert surgeon independently performing minimally invasive percutaneous neprolitholapaxy (PCNL) excluding the influence of the expert in the learning curve...
  46. doi request reprint Can the burden of follow-up in low-grade noninvasive bladder cancer be reduced by photodynamic diagnosis, perioperative instillations, imaging, and urine markers?
    Georgios Gakis
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Curr Opin Urol 20:388-92. 2010
    ....
  47. doi request reprint Post-chemotherapy laparoscopic retroperitoneal lymph-node dissection in testis cancer patients
    Rafael Maldonado-Valadez
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    J Endourol 21:1501-4. 2007
    ..To reduce the morbidity and to improve the acceptance of RPLND, laparoscopy has been introduced. In this study, we describe our experiences with laparoscopic RPLND for stage II testicular carcinoma after chemotherapy...
  48. doi request reprint Comparison of the new American Joint Committee on Cancer substratification in node-negative pT2 urothelial carcinoma of the bladder: analysis of patient outcomes in a contemporary series
    Georgios Gakis
    Department of Urology, Eberhard Karls University, Tubingen, Germany
    BJU Int 107:919-23. 2011
    ....
  49. doi request reprint Essential differences in ligand presentation and T cell epitope recognition among HLA molecules of the HLA-B44 supertype
    Nina Hillen
    Department of Immunology, University of Tubingen, Tubingen, Germany
    Eur J Immunol 38:2993-3003. 2008
    ..Taken together, these results challenge the common paradigm of broadly presented epitopes within this supertype...
  50. doi request reprint Development of a new outcome prediction model in carcinoma invading the bladder based on preoperative serum C-reactive protein and standard pathological risk factors: the TNR-C score
    Georgios Gakis
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    BJU Int 108:1800-5. 2011
    ....
  51. ncbi request reprint Steerable antegrade stenting: a new trick of the trade
    Udo Nagele
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Int Braz J Urol 33:389-93; discussion 393-4. 2007
    ..In the present study, this simple technique is used to position a floppy guide wire through a modified needle directly through the renal pelvis into the ureter...
  52. ncbi request reprint Quantification of tumor cell burden by analysis of single cell lymph node disaggregates in metastatic prostate cancer
    David Schilling
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Prostate 70:1110-8. 2010
    ..We present a novel technique (1) to detect early tumor cell dissemination and (2) to quantify the true tumor burden...
  53. ncbi request reprint HLA ligand profiles of primary renal cell carcinoma maintained in metastases
    Juliane Sarah Stickel
    Department of Immunology, Institute for Cell Biology, University of Tubingen, Tubingen, Germany
    Cancer Immunol Immunother 58:1407-17. 2009
    ..Furthermore we were able to identify several peptides derived from tumor-associated antigens that are suitable for vaccination of metastatic RCC...
  54. doi request reprint Cystectomy in women
    David Schilling
    Department of Urology, University Hospital Tubingen, Tubingen, Germany
    BJU Int 102:1289-95. 2008
    ..However, the oncological result should never be endangered by organ preservation...
  55. doi request reprint Initial clinical experience with full-length metal ureteral stents for obstructive ureteral stenosis
    Udo Nagele
    Department of Urology, University of Tuebingen, Hoppe Seyler Str 3, 72076 Tuebingen, Germany
    World J Urol 26:257-62. 2008
    ..In this contribution, a long-term experience with a new full-length, metal indwelling stent is presented...
  56. ncbi request reprint Clinical experience with survivin as a biomarker for urothelial bladder cancer
    Marcus Horstmann
    Department of Urology, Eberhard Karls University Tuebingen, Hoppe Seyler Str 3, 72076, Tuebingen, Germany
    World J Urol 28:399-404. 2010
    ..Data were also analyzed for possible influences of secondary urological findings on survivin measurements...
  57. doi request reprint Hexyl aminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: a critical review of the current literature
    Michael Rink
    Department of Urology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 64:624-38. 2013
    ....
  58. doi request reprint Serum receptor activator of nuclear factor κB ligand (RANKL) levels predict biochemical recurrence in patients undergoing radical prostatectomy
    Tilman Todenhöfer
    Department of Urology, University Hospital Tubingen, Tubingen, Germany
    BJU Int 113:152-9. 2014
    ..Both high levels of RANKL and a higher RANKL/OPG ratio are independent predictors of early biochemical recurrence in these patients...
  59. doi request reprint Galectin-3 expression in prostate cancer and benign prostate tissues: correlation with biochemical recurrence
    Judith S Knapp
    Department of Urology, Diakonie Klinikum Stuttgart, Stuttgart, Germany
    World J Urol 31:351-8. 2013
    ..Our aim was to examine Gal-3 expression in tumor, benign tissue adjacent to the tumor (adjacent-benign) and benign prostate specimens and correlated it with biochemical recurrence...
  60. ncbi request reprint The rationale for radical cystectomy as primary therapy for T4 bladder cancer
    Udo Nagele
    Department of Urology, Eberhard Karls University Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    World J Urol 25:401-5. 2007
    ..Additionally, satisfying clinical outcome is observed even in a substantial number of elderly patients...
  61. doi request reprint Endoscopic inguinofemoral lymphadenectomy--extended follow-up
    Christian Schwentner
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    J Endourol 27:497-503. 2013
    ..Open lymphadenectomy (O-IFLA) exhibits complication rates of more than 50%. We are demonstrating our extended experience with a modified endoscopic approach (E-IFLA) for groin lymphadenectomy...
  62. ncbi request reprint Clinical outcome after cystectomy in patients with lymph node-positive bladder cancer
    Udo Nagele
    Department of Urology, University of Tuebingen, Hoppe Seyler Str 3, Tuebingen 72076, Germany
    Expert Rev Anticancer Ther 6:871-6. 2006
    ..Recognizing the inevitably poor clinical prognosis in cases with gross nodal involvement (N3), the clinical value of an extended lymph node dissection in these patients is very questionable...
  63. doi request reprint Influence of urinary tract instrumentation and inflammation on the performance of urine markers for the detection of bladder cancer
    Tilman Todenhöfer
    Department of Urology, University Hospital, Tuebingen, Germany
    Urology 79:620-4. 2012
    ..The specificity of urine markers for urothelial cancer is subject to exogenous factors. There is evidence that nuclear matrix protein 22 (NMP22) is influenced by urinary tract infection and instrumented urinary sampling (IUS)...
  64. ncbi request reprint MRI-guided biopsy of the prostate increases diagnostic performance in men with elevated or increasing PSA levels after previous negative TRUS biopsies
    Aristotelis G Anastasiadis
    Department of Urology, Comprehensive Cancer Center CCC Tübingen, Eberhard Karls Universitat Tubingen, Germany
    Eur Urol 50:738-48; discussion 748-9. 2006
    ....
  65. pmc Insulin receptor isoforms A and B as well as insulin receptor substrates-1 and -2 are differentially expressed in prostate cancer
    Martin Heni
    Department of Internal Medicine, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tubingen, Tubingen, Germany
    PLoS ONE 7:e50953. 2012
    ..Since this is yet unclear for prostate cancer, we investigated IR isoform composition and IRS balance in prostate cancer compared to benign and tumor adjacent benign prostate tissue and brought this into relation to cell proliferation...
  66. doi request reprint Inflammatory prognostic markers in clear cell renal cell carcinoma - preoperative C-reactive protein does not improve predictive accuracy
    Jens Bedke
    Department of Urology, Eberhard Karls University Tuebingen, Germany
    BJU Int 110:E771-7. 2012
    ..25 mg/dL to be best to stratify patients at risk of cancer-specific mortality. However, this CRP-based prediction added no additional information compared to a clinico-pathological based model...
  67. doi request reprint SFRP1 CpG island methylation locus is associated with renal cell cancer susceptibility and disease recurrence
    Faranaz Atschekzei
    Department of Urology, Medizinische Hochschule Hannover, Hannover, Germany
    Epigenetics 7:447-57. 2012
    ..Our data underline the need to further analyze the tissue specific risks conferred by methylated loci for the development of human cancers...
  68. doi request reprint Impact of clinical parameters on the diagnostic accuracy of endorectal coil MRI for the detection of prostate cancer
    Daniela Colleselli
    Department of Urology, Eberhard Karls University Tubingen, Tubingen, Germany
    Urol Int 86:393-8. 2011
    ..There is little evidence on patient characteristics affecting its diagnostic performance. We evaluate the influence of clinical and histological parameters on the accuracy of endoMRI...
  69. doi request reprint Prostate cancer gene 3 (PCA3): development and internal validation of a novel biopsy nomogram
    Felix K Chun
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 56:659-67. 2009
    ..Urinary prostate cancer gene 3 (PCA3) represents a promising novel marker of prostate cancer detection...
  70. doi request reprint Tumorsize dependent detection rate of endorectal MRI of prostate cancer--a histopathologic correlation with whole-mount sections in 70 patients with prostate cancer
    Matthias C Roethke
    Department of Diagnostic and Interventional Radiology, University of Tuebingen, Hoppe Seyler Str 3, 72076 Tuebingen, Germany
    Eur J Radiol 79:189-95. 2011
    ..To evaluate the value of T2w endorectal MRI (eMRI) for correct detection of tumor foci within the prostate regarding tumor size...
  71. ncbi request reprint Morphologic, functional, and metabolic magnetic resonance imaging-guided prostate biopsy in a patient with prior negative transrectal ultrasound-guided biopsies and persistently elevated prostate-specific antigen levels
    Matthias P Lichy
    Department of Urology, Comprehensive Cancer Center Tübingen, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Urology 69:1208.e5-8. 2007
    ..Magnetic resonance imaging-guided prostate biopsy was successfully performed. All specimens taken from the lesion showed a Gleason 5 tubular adenocarcinoma with low proliferative activity...
  72. doi request reprint Minimally invasive percutaneous nephrolithotomy: a comparative study of the management of small and large renal stones
    Mohamed F Abdelhafez
    Department of Urology, Eberhard Karls Universitat Tubingen, Germany
    Urology 81:241-5. 2013
    ....
  73. doi request reprint Biomechanical proof of barbed sutures for the efficacy of laparoscopic pyeloplasty
    Bastian Amend
    Department of Urology, Eberhard Karl University of Tuebingen, Tuebingen, Germany
    J Endourol 26:540-4. 2012
    ..We compared a self-retaining suture (SRS) Quill(®) (Angiotech, Canada) with a standard monofilament suture to further investigate their biomechanical and urodynamic aspects...
  74. doi request reprint Flow matters: irrigation flow differs in flexible ureteroscopes of the newest generation
    Stephan Kruck
    Department of Urology, University of Tuebingen, Germany
    Urol Res 39:483-6. 2011
    ..This study showed inter-manufactural differences in terms of irrigation flow rates with either empty or occupied working channels resulting in significant alterations in endoscopic view...
  75. ncbi request reprint Size does matter: 1.5 Fr. stone baskets almost double irrigation flow during flexible ureteroscopy compared to 1.9 Fr. stone baskets
    Udo Nagele
    Department of Urology, University of Tuebingen, Hoppe Seyler Str 3, Tuebingen 72076, Germany
    Urol Res 34:389-92. 2006
    ..This study confirmed the subjective impression of inadequate description of relevant basket diameters as well as that of a significant improvement of irrigation flow with the newest generation of stone baskets with smaller diameters...
  76. doi request reprint Caveolin 1 mRNA is overexpressed in malignant renal tissue and might serve as a novel diagnostic marker for renal cancer
    Sandra Waalkes
    Department of Urology, Hannover Medical School, Germany
    Biomark Med 5:219-25. 2011
    ..The aim of this study was to elucidate the expression of caveolin (CAV)1 in the development of renal cell cancer (RCC) and to determine a possible prognostic relevance for optimal clinical management...
  77. doi request reprint Single-stage dorsal inlay full-thickness genital skin grafts for hypospadias reoperations: extended follow up
    Christian Schwentner
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    J Pediatr Urol 7:65-71. 2011
    ..To report our extended experience with single-stage genital skin graft urethroplasty for complex hypospadias reoperations...
  78. doi request reprint Incidental prostate cancer at radical cystoprostatectomy: implications for apex-sparing surgery
    Georgios Gakis
    Department of Urology, Eberhard Karls University, Tubingen, Germany
    BJU Int 105:468-71. 2010
    ....
  79. doi request reprint The periprostatic autonomic nerves--bundle or layer?
    Karl Dietrich Sievert
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Eur Urol 54:1109-16. 2008
    ..The functional outcome of a nerve-sparing radical prostatectomy (RP) depends on the knowledge of autonomic nerve distribution in correlation to the prostate...
  80. doi request reprint In vitro investigations of tissue-engineered multilayered urothelium established from bladder washings
    Udo Nagele
    Department of Urology, University of Tubingen, Tubingen, Germany
    Eur Urol 54:1414-22. 2008
    ..The aim of this study was to raise primary monolayer cultures of HUCs from bladder washings, to generate multilayered urothelial sheets in vitro, to characterise the sheets immunologically, and to prove their viability...
  81. ncbi request reprint Cathepsin D serum levels are not a valid serum marker in renal cell carcinoma
    Axel S Merseburger
    Department of Urology, Eberhard Karls University Tuebingen, Tuebingen, Germany
    Urol Int 79:41-3. 2007
    ..It was the aim of this study to evaluate the serum levels of cathepsin D (Cath D) as a diagnostic tool in patients with renal cell carcinoma (RCC) in comparison with healthy volunteers...
  82. ncbi request reprint Docetaxel, estramustine and prednisone for hormone-refractory prostate cancer: a single-center experience
    Angela Boehmer
    Department of Urology, University of Tuebingen Medical Center, Tuebingen, Germany
    Anticancer Res 25:4481-6. 2005
    ..We, therefore, wanted to evaluate a docetaxel-based regimen, with regard to efficacy and tolerability, in men with HRPC at our institution...
  83. doi request reprint Dorsal onlay skin graft urethroplasty in patients older than 65 years
    Christian Schwentner
    Department of Urology, Eberhard Karls University Tuebingen, Germany
    Urology 76:465-70. 2010
    ..Despite an aging population, the results of this technique in elderly patients have not yet been explicitly reported. We present our experience with dorsal onlay graft urethroplasty in this cohort...
  84. doi request reprint From tissue engineering to regenerative medicine in urology--the potential and the pitfalls
    Gerhard Feil
    Dept of Urology, University of Tuebingen, Hoppe Seyler Strasse 3, Tuebingen, Germany
    Adv Drug Deliv Rev 63:375-8. 2011
    ..Thus, other cell sources and harvesting techniques like placenta and adipose tissue for mesenchymal stem cells and bladder irrigation for urothelial cells require closer investigation...
  85. ncbi request reprint Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas
    Sebastian Attig
    Department of Immunology, Institute for Cell Biology, Eberhard Karls University, Tubingen, Germany
    Cancer Res 69:8412-9. 2009
    ..Additionally, several populations of CD4(+) and CD8(+) regulatory T cells were identified that may synergize to locally dampen antitumor T-cell responses...
  86. ncbi request reprint Laser fragmentation of foreign bodies in the urinary tract: an in vitro study and clinical application
    Jens Bedke
    Department of Urology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    World J Urol 28:177-80. 2010
    ..We postulated that foreign objects could be fragmented by Holmium:YAG laser and investigated its effect on objects of varying composition...
  87. ncbi request reprint Novel therapeutic options in metastatic renal cancer - review and post ASCO 2007 update
    Stephan Kruck
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Rev Recent Clin Trials 3:212-6. 2008
    ..This review presents and discusses the effectiveness of the most frequently used substances in mono- or combination regimes based on current data of the ASCO 2007...
  88. doi request reprint Interpretation of the prostate cancer gene 3 in reference to the individual clinical background: implications for daily practice
    David Schilling
    Department of Urology, University Hospital Tubingen, Tubingen, Germany
    Urol Int 85:159-65. 2010
    ..We report our experience with the test in a routine clinical setting and discuss the interpretation of the test results in the context of the individual patient history...
  89. ncbi request reprint Hexaminolevulinate is equal to 5-aminolevulinic acid concerning residual tumor and recurrence rate following photodynamic diagnostic assisted transurethral resection of bladder tumors
    Maximilian Burger
    Department of Urology, Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    Urology 74:1282-6. 2009
    ..Although numerous and specific data exist on the older substance ALA, considerably less are available on hex, the only agent approved however. To date no such report has been published...
  90. ncbi request reprint Radical cystectomy and orthotopic bladder replacement in females
    Udo Nagele
    Department of Urology, University of Tuebingen, Germany
    Eur Urol 50:249-57. 2006
    ..Several studies have been published, outlining both the anatomical and oncological aspects of such an approach...
  91. ncbi request reprint Closing the tract of mini-percutaneous nephrolithotomy with gelatine matrix hemostatic sealant can replace nephrostomy tube placement
    Udo Nagele
    Department of Urology, University of Tuebingen, Tuebingen, Germany
    Urology 68:489-93; discussion 493-4. 2006
    ..To investigate the outcomes using gelatine matrix hemostatic sealant to close the tract after mini-percutaneous nephrolithotomy (mini-PCNL), resulting in a tubeless setting...
  92. doi request reprint Virtual bladder tumor transurethral resection: an objective evaluation tool to overcome learning curves with and without photodynamic diagnostics
    Stephan Kruck
    Department of Urology, University of Tubingen, Tubingen, Germany
    Urol Int 87:138-42. 2011
    ..The aim of this research was to determine whether VR transurethral bladder tumor resection (TURBT) with and without photodynamic diagnostic (PDD) can improve endourological skills in novice and trained endoscopists...
  93. ncbi request reprint Disseminated and circulating tumor cells for monitoring chemotherapy in urological tumors
    Stephan Kruck
    Department of Urology, Eberhard Karls University Tuebingen, Hoppe Seyler Str 3, D 72076 Tuebingen, Germany
    Anticancer Res 31:2053-7. 2011
    ..Advanced technologies offer new options for estimating the risk of progression after curative-intended surgery and may allow a more effective monitoring of disease progression or response to therapy...