Andre F Steinert

Summary

Country: Germany

Publications

  1. pmc Major biological obstacles for persistent cell-based regeneration of articular cartilage
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Arthritis Res Ther 9:213. 2007
  2. pmc Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, Orthopaedic Clinic, König Ludwig Haus, Julius Maximilians University, Brettreichstrasse 11, 97074 Wurzburg, Germany
    Arthritis Res Ther 11:R148. 2009
  3. doi Snapping elbow caused by hypertrophic synovial plica in the radiohumeral joint: a report of three cases and review of literature
    Andre F Steinert
    Division of Sports Medicine and Arthroscopy, Orthopaedic Clinic, König Ludwig Haus, Julius Maximilians University Würzburg, Brettreichstrasse 11, Wurzburg, Germany
    Arch Orthop Trauma Surg 130:347-51. 2010
  4. pmc Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells
    Andre F Steinert
    Department of Orthopaedic Surgery, König Ludwig Haus, Orthopaedic Center for Musculoskeletal Research, Julius Maximilians University, Wurzburg, Germany
    Tissue Eng Part A 17:1375-88. 2011
  5. pmc BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells
    Meike Haddad-Weber
    Orthopedic Center for Musculoskeletal Research, Department of Orthopedic Surgery, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Cytotherapy 12:505-13. 2010
  6. pmc Concepts in gene therapy for cartilage repair
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Injury 39:S97-113. 2008
  7. pmc Concise review: the clinical application of mesenchymal stem cells for musculoskeletal regeneration: current status and perspectives
    Andre F Steinert
    Department of Orthopaedic Surgery, König Ludwig Haus, Orthopaedic Center for Musculoskeletal Research, Julius Maximilians University, Wurzburg, Germany
    Stem Cells Transl Med 1:237-47. 2012
  8. doi Cell delivery therapeutics for musculoskeletal regeneration
    Ulrich Nöth
    Orthopaedic Center for Musculoskeletal Research, Department of Orthopaedic Surgery, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Adv Drug Deliv Rev 62:765-83. 2010
  9. ncbi In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament
    Andre F Steinert
    Division of Gene Therapy, Orthopedic Center for Musculoskeletal Research, Orthopedic Clinic, König Ludwig Haus, Julius Maximilians University, Brettreichstrasse 11, D 97074 Wurzburg, Germany
    Biomaterials 29:904-16. 2008
  10. pmc Reduced postoperative pain in total hip arthroplasty after minimal-invasive anterior approach
    Sascha Goebel
    Department of Orthopaedic Surgery, König Ludwig Haus, Julius Maximilians University, Brettreichstr 11, 97074, Wurzburg, Germany
    Int Orthop 36:491-8. 2012

Collaborators

Detail Information

Publications15

  1. pmc Major biological obstacles for persistent cell-based regeneration of articular cartilage
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Arthritis Res Ther 9:213. 2007
    ..The current conceptual basis of the major biological obstacles for persistent cell-based regeneration of articular cartilage is discussed, as well as future trends to overcome these limitations...
  2. pmc Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, Orthopaedic Clinic, König Ludwig Haus, Julius Maximilians University, Brettreichstrasse 11, 97074 Wurzburg, Germany
    Arthritis Res Ther 11:R148. 2009
    ..The present study compares bone morphogenetic protein (BMP)-4 and BMP-2 gene transfer as agents of chondrogenesis and hypertrophy in human primary mesenchymal stem cells (MSCs) maintained as pellet cultures...
  3. doi Snapping elbow caused by hypertrophic synovial plica in the radiohumeral joint: a report of three cases and review of literature
    Andre F Steinert
    Division of Sports Medicine and Arthroscopy, Orthopaedic Clinic, König Ludwig Haus, Julius Maximilians University Würzburg, Brettreichstrasse 11, Wurzburg, Germany
    Arch Orthop Trauma Surg 130:347-51. 2010
    ..Surgical management in all three cases comprised arthroscopic diagnosis confirmation and removal of the synovial plicae, leading to excellent outcomes at 6-12 months follow-up...
  4. pmc Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells
    Andre F Steinert
    Department of Orthopaedic Surgery, König Ludwig Haus, Orthopaedic Center for Musculoskeletal Research, Julius Maximilians University, Wurzburg, Germany
    Tissue Eng Part A 17:1375-88. 2011
    ..We conclude that the cells that emigrate from damaged ACLs are MSCs and that they have the potential to provide the basis for a superior, biological repair of this ligament...
  5. pmc BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells
    Meike Haddad-Weber
    Orthopedic Center for Musculoskeletal Research, Department of Orthopedic Surgery, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Cytotherapy 12:505-13. 2010
    ..To date there are only very few data available on the ligamentogenic differentiation capacity of mesenchymal stromal/progenitor cells (MSC) and anterior cruciate ligament (ACL) fibroblasts...
  6. pmc Concepts in gene therapy for cartilage repair
    Andre F Steinert
    Orthopaedic Center for Musculoskeletal Research, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Injury 39:S97-113. 2008
    ..This review presents the current status of gene therapy for cartilage healing and highlights some of the remaining challenges...
  7. pmc Concise review: the clinical application of mesenchymal stem cells for musculoskeletal regeneration: current status and perspectives
    Andre F Steinert
    Department of Orthopaedic Surgery, König Ludwig Haus, Orthopaedic Center for Musculoskeletal Research, Julius Maximilians University, Wurzburg, Germany
    Stem Cells Transl Med 1:237-47. 2012
    ..In summary, this review presents the scientific background, current state, and implications of clinical mesenchymal stem cell application in the musculoskeletal system and provides perspectives for future developments...
  8. doi Cell delivery therapeutics for musculoskeletal regeneration
    Ulrich Nöth
    Orthopaedic Center for Musculoskeletal Research, Department of Orthopaedic Surgery, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Adv Drug Deliv Rev 62:765-83. 2010
    ..This review will focus on the functional approach of using biomaterial scaffold materials as cell carriers for musculoskeletal applications, as well as the use of cell-based gene therapy for tissue engineering and regeneration...
  9. ncbi In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament
    Andre F Steinert
    Division of Gene Therapy, Orthopedic Center for Musculoskeletal Research, Orthopedic Clinic, König Ludwig Haus, Julius Maximilians University, Brettreichstrasse 11, D 97074 Wurzburg, Germany
    Biomaterials 29:904-16. 2008
    ..These data confirm the promise of using vector-laden hydrogels for the in situ delivery of genes to cells within damaged ligaments and suggest novel possibilities for the biological repair of the ACL...
  10. pmc Reduced postoperative pain in total hip arthroplasty after minimal-invasive anterior approach
    Sascha Goebel
    Department of Orthopaedic Surgery, König Ludwig Haus, Julius Maximilians University, Brettreichstr 11, 97074, Wurzburg, Germany
    Int Orthop 36:491-8. 2012
    ....
  11. pmc Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer
    Andre F Steinert
    Harvard Medical School, Center for Molecular Orthopaedics, Boston, Massachusetts, USA
    Tissue Eng Part A 15:1127-39. 2009
    ....
  12. doi Surgical management of a double-layered patella: a case report
    Sascha Goebel
    Division of Sports Medicine and Arthroscopy, Orthopedic Clinic, König Ludwig Haus, University of Wurzburg, Brettreichstr 11, 97074, Wurzburg, Germany
    Arch Orthop Trauma Surg 129:1071-5. 2009
    ..Surgical management in this case of DLP comprised open debridement of the soft tissue interface and fusion of the two osseous layers using double-threaded screws leading to an excellent outcome at 12 months follow-up...
  13. doi Foamy virus-adenovirus hybrid vectors for gene therapy of the arthritides
    Conrad Weber
    University of Wurzburg, Department of Virology and Immunobiology, Wurzburg, Germany
    J Gene Med 15:155-67. 2013
    ..In the present study, we have generated and investigated the use of safe FAD vectors for direct gene delivery to joints...
  14. doi Technology insight: adult mesenchymal stem cells for osteoarthritis therapy
    Ulrich Nöth
    Division of Tissue Engineering at Orthopedic Center for Musculoskeletal Research, König Ludwig Haus, Julius Maximilians University, Wurzburg, Germany
    Nat Clin Pract Rheumatol 4:371-80. 2008
    ..Promising experimental and clinical data are beginning to emerge in support of the use of MSCs for regenerative applications...
  15. doi Generation of an improved foamy virus vector by dissection of cis-acting sequences
    Tatiana Wiktorowicz
    Universitat Wurzburg, Institut fur Virologie und Immunbiologie, Wurzburg, Germany
    J Gen Virol 90:481-7. 2009
    ..In essence, we designed a new FV vector that bears approximately 850 bp less of CAS than previously established vectors and is fully functional when analysed to transduce cell lines and primary human cells...