K Sotlar

Summary

Country: Germany

Publications

  1. pmc Acute myeloid leukaemia with t(8;21) associated with "occult" mastocytosis. Report of an unusual case and review of the literature
    H W Bernd
    Institute of Pathology, Medical University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    J Clin Pathol 57:324-8. 2004
  2. ncbi request reprint Splenic mastocytosis: report of two cases and detection of the transforming somatic C-KIT mutation D816V
    Friedrich Wimazal
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Leuk Lymphoma 45:723-9. 2004
  3. ncbi request reprint Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection
    Hans Neubauer
    University Women s Hospital, Tubingen, Germany
    Electrophoresis 27:1840-52. 2006
  4. ncbi request reprint [The interdisciplinary approach to improve treatment quality of prostate cancer. Optimized nerve sparing in radical prostatectomy]
    K D Sievert
    Universitatsklinik fur Urologie, Universitatsklinikum Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen
    Urologe A 46:1104-12. 2007
  5. pmc Simultaneous adrenal and extra-adrenal myelolipoma - an uncommon incident: case report and review of the literature
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    World J Surg Oncol 6:72. 2008
  6. pmc One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Pathol 162:737-46. 2003
  7. ncbi request reprint Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076, Tubingen, Germany
    Leuk Res 26:979-84. 2002
  8. pmc Detection and typing of human papillomavirus by e6 nested multiplex PCR
    K Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, 72076 Tubingen, Germany
    J Clin Microbiol 42:3176-84. 2004
  9. ncbi request reprint Detection of high-risk human papillomavirus E6 and E7 oncogene transcripts in cervical scrapes by nested RT-polymerase chain reaction
    Karl Sotlar
    Institute of Pathology, University of Tuebingen, Germany
    J Med Virol 74:107-16. 2004
  10. pmc Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD8
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    J Mol Diagn 10:58-66. 2008

Collaborators

Detail Information

Publications56

  1. pmc Acute myeloid leukaemia with t(8;21) associated with "occult" mastocytosis. Report of an unusual case and review of the literature
    H W Bernd
    Institute of Pathology, Medical University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    J Clin Pathol 57:324-8. 2004
    ....
  2. ncbi request reprint Splenic mastocytosis: report of two cases and detection of the transforming somatic C-KIT mutation D816V
    Friedrich Wimazal
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Leuk Lymphoma 45:723-9. 2004
    ..In summary, our data show that the spleen can be a primary site of disease in rare cases of SM. Mastocytosis should therefore be considered as a (rare) differential diagnosis in patients with splenomegaly of unknown etiology...
  3. ncbi request reprint Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection
    Hans Neubauer
    University Women s Hospital, Tubingen, Germany
    Electrophoresis 27:1840-52. 2006
    ..This study demonstrates the potential of ProteoTope and LCM to enable extremely sensitive and precise differential analyses from well-defined primary clinical specimen...
  4. ncbi request reprint [The interdisciplinary approach to improve treatment quality of prostate cancer. Optimized nerve sparing in radical prostatectomy]
    K D Sievert
    Universitatsklinik fur Urologie, Universitatsklinikum Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen
    Urologe A 46:1104-12. 2007
    ..After sufficient oncological treatment of prostate cancer the life quality becomes most important. A multi disciplinary research network aims to optimize the diagnostics and the resulting treatment of prostate cancer...
  5. pmc Simultaneous adrenal and extra-adrenal myelolipoma - an uncommon incident: case report and review of the literature
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    World J Surg Oncol 6:72. 2008
    ..Other soft tissue tumours such as well-differentiated liposarcomas appear morphological almost identical. Preoperative imaging and especially biopsy are important tools to diagnose these lesions...
  6. pmc One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Pathol 162:737-46. 2003
    ....
  7. ncbi request reprint Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076, Tubingen, Germany
    Leuk Res 26:979-84. 2002
    ....
  8. pmc Detection and typing of human papillomavirus by e6 nested multiplex PCR
    K Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, 72076 Tubingen, Germany
    J Clin Microbiol 42:3176-84. 2004
    ..9% (124 of 259) of the patients. In conclusion, the novel NMPCR method is a sensitive and useful tool for HPV DNA detection, especially when exact HPV genotyping and the identification of multiple HPV infections are required...
  9. ncbi request reprint Detection of high-risk human papillomavirus E6 and E7 oncogene transcripts in cervical scrapes by nested RT-polymerase chain reaction
    Karl Sotlar
    Institute of Pathology, University of Tuebingen, Germany
    J Med Virol 74:107-16. 2004
    ..Future applications of the assay described may include the monitoring of women in studies investigating antiviral treatment or vaccination...
  10. pmc Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD8
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    J Mol Diagn 10:58-66. 2008
    ..Altogether, these data suggest that KIT(D816V+) SM can co-exist with JAK2(V617F+) CIMF and that, in some of these SM-CIMF cases, the two mutations are present in the neoplastic cells of both disease components...
  11. pmc The tryptase positive compact round cell infiltrate of the bone marrow (TROCI-BM): a novel histopathological finding requiring the application of lineage specific markers
    H P Horny
    University of Lubeck, Institute of Pathology, Lubeck, Germany
    J Clin Pathol 59:298-302. 2006
    ....
  12. ncbi request reprint Detection of human papillomavirus type 16 E6/E7 oncogene transcripts in dysplastic and nondysplastic cervical scrapes by nested RT-PCR
    K Sotlar
    Institute for Pathology, University of Tubingen, Tubingen, Germany
    Gynecol Oncol 69:114-21. 1998
    ....
  13. doi request reprint Differential diagnoses of systemic mastocytosis in routinely processed bone marrow biopsy specimens: a review
    H P Horny
    Institute of Pathology, Ansbach, Germany
    Pathobiology 77:169-80. 2010
    ....
  14. pmc An unusual case of systemic mastocytosis associated with chronic lymphocytic leukaemia (SM-CLL)
    H P Horny
    Institute of Pathology, University of Lubeck, Germany
    J Clin Pathol 59:264-8. 2006
    ..This report contributes to the differential diagnosis of ISM by demonstrating that such lymphocytic aggregates may be neoplastic...
  15. pmc "Occult" mastocytosis with activating c-kit point mutation evolving into systemic mastocytosis associated with plasma cell myeloma and secondary amyloidosis
    K Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    J Clin Pathol 59:875-8. 2006
    ..This finding was preliminarily termed "occult" mastocytosis...
  16. pmc Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: a histopathological challenge
    H P Horny
    Institute of Pathology, University of Lubeck, D 23538 Lubeck, Germany
    J Clin Pathol 57:604-8. 2004
    ....
  17. ncbi request reprint Human papillomavirus type 16-associated primary squamous cell carcinoma of the rectum
    K Sotlar
    Institute of Pathology, University of Tubingen, Germany
    Gastroenterology 120:988-94. 2001
    ..In line with the well-established concept of HPV-associated anogenital carcinogenesis, our results strongly suggest an etiologic role of HPV-16 in the pathogenesis of the metaplasia-dysplasia-SCC sequence in the case described...
  18. ncbi request reprint Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease
    Burkhard D Bültmann
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Hum Pathol 34:92-5. 2003
    ..We speculate that, due to the high viral load in cardiac ECs, PVB19 infection of endothelial cells was sufficient to induce impaired coronary microcirculation with secondary cardiac myocyte necrosis...
  19. ncbi request reprint Does intensive histopathological workup by serial sectioning increase the detection of lymph node micrometastasis in patients with primary cutaneous melanoma?
    H J Blaheta
    Department of Dermatology, Skin Cancer Program, Eberhard Karls University, Tuebingen, Germany
    Melanoma Res 11:57-63. 2001
    ..Patients with melanoma cells detected exclusively by RT-PCR, however, were shown to be at increased risk for tumour recurrence...
  20. ncbi request reprint Influence of tumor biological factors on tumor cell dissemination in primary breast cancer
    T Fehm
    Department of Obstetrics and Gynecology University of Tuebingen, Calwerstrasse 7, D 72076 Tuebingen, Germany
    Anticancer Res 24:4211-6. 2004
    ..The aim of this study was to identify those features of the primary tumor related to the presence of disseminated tumor cells in the BM...
  21. ncbi request reprint Additional reverse transcription-polymerase chain reaction of peripheral slices is not superior to analysis of the central slice in sentinel lymph nodes from melanoma patients
    H J Blaheta
    Department of Dermatology, Skin Cancer Program, and Department of Pathology, Eberhard Karls University, Liebermeister Str 25, 72076 Tuebingen, Germany
    Br J Dermatol 150:477-83. 2004
    ..Reverse transcription-polymerase chain reaction (RT-PCR) has been used as a sensitive means of detecting tumour cells in SLNs...
  22. ncbi request reprint [Paraganglioma in the area of the head and neck. A review of molecular genetic research]
    S Braun
    HNO Universitätsklinik, Tubingen
    HNO 52:11-7. 2004
    ..Thus, SDHD is the first known tumor suppressor gene encoding a mitochondrial protein. In this article we summarize the current state of knowledge concerning the development of paragangliomas...
  23. ncbi request reprint Examination of regional lymph nodes by sentinel node biopsy and molecular analysis provides new staging facilities in primary cutaneous melanoma
    H J Blaheta
    Department of Dermatology, Skin Cancer Program, Eberhard Karls University, Tuebingen, Germany
    J Invest Dermatol 114:637-42. 2000
    ..These data may have an impact on future tumor classifications of primary cutaneous melanoma...
  24. ncbi request reprint Lymph node micrometastases of cutaneous melanoma: increased sensitivity of molecular diagnosis in comparison to immunohistochemistry
    H J Blaheta
    Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
    Int J Cancer 79:318-23. 1998
    ..0001). Patients with nodal micrometastases identified exclusively by RT-PCR had significantly higher tumor thickness as compared to patients with negative results by RT-PCR (p < 0.01)...
  25. ncbi request reprint Mastocytosis: state of the art
    Hans Peter Horny
    Institute of Pathology, Ansbach, Germany
    Pathobiology 74:121-32. 2007
    ....
  26. ncbi request reprint Parvovirus B19: a pathogen responsible for more than hematologic disorders
    Burkhard D Bültmann
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    Virchows Arch 442:8-17. 2003
    ..Because treatment of lytic PVB19 infection has been successfully applied, the pathologist should be alerted to include PVB19 into the diagnostic spectrum of viral disease, especially in immunocompromised patients...
  27. ncbi request reprint CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Surg Pathol 28:1319-25. 2004
    ..CD25 therefore appears to be a reliable immunohistochemical marker for the discrimination of neoplastic from normal/reactive MCs, with potential as a diagnostic tool in SM...
  28. ncbi request reprint Delineation of patterns of bone marrow mast cell infiltration in systemic mastocytosis: value of CD25, correlation with subvariants of the disease, and separation from mast cell hyperplasia
    Manuela Krokowski
    Institute of Pathology, University of Lubeck, Lubeck, Germany
    Am J Clin Pathol 124:560-8. 2005
    ..Our data show that the infiltration pattern in SM correlates with the disease subtype and should be recognized as an important aspect in the histomorphologic evaluation of the bone marrow...
  29. doi request reprint Metastasis of malignant melanoma in the ureter: possible algorithms for a therapeutic approach
    Georgios Gakis
    Department of Urology, University Hospital Tuebingen, Eberhard Karls University, Tuebingen, Germany
    Int J Urol 16:407-9. 2009
    ..Based on this case as well as on recent published reports, we propose a possible algorithm for the treatment of metastatic melanoma of the upper urinary tract...
  30. doi request reprint Quantification of tumor cell burden by analysis of single cell lymph node disaggregates in metastatic prostate cancer
    David Schilling
    Department of Urology, Eberhard Karls University, Tuebingen, Germany
    Prostate 70:1110-8. 2010
    ..We present a novel technique (1) to detect early tumor cell dissemination and (2) to quantify the true tumor burden...
  31. doi request reprint Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD)
    Karl Sotlar
    Institute of Pathology, University of Munich, Germany
    J Pathol 220:586-95. 2010
    ....
  32. doi request reprint Modified concept for radioisotope-guided sentinel lymph node dissection in prostate cancer
    David Schilling
    Department of Urology, Eberhard Karls University Tuebingen, Hoppe Seyler Str 3, 72076, Tuebingen, Germany
    World J Urol 28:715-20. 2010
    ..To present a modified concept for sentinel lymph node (SLN)-guided pelvic lymph node dissection in prostate cancer...
  33. doi request reprint Evaluation of mast cell activation syndromes: impact of pathology and immunohistology
    H P Horny
    Institute of Pathology, Ludwig Maximilians University, Munich, Germany
    Int Arch Allergy Immunol 159:1-5. 2012
    ..When the activating point mutant KIT D816V is detectable but criteria for diagnosis of mastocytosis are not completely met, a so-called (mono)clonal MCAS as a subvariant of primary MCAS should be diagnosed...
  34. ncbi request reprint Detection of melanoma cells in sentinel lymph nodes, bone marrow and peripheral blood by a reverse transcription-polymerase chain reaction assay in patients with primary cutaneous melanoma: association with Breslow's tumour thickness
    H J Blaheta
    Department of Dermatology, Skin Cancer Programme, Eberhard Karls University, Liebermeister Str 25, 72076 Tubingen, Germany
    Br J Dermatol 145:195-202. 2001
    ..Tyrosinase reverse transcription-polymerase chain reaction (RT-PCR) has been shown to be highly sensitive in detecting tumour cells in melanoma patients...
  35. ncbi request reprint Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis
    Christina S Schuetz
    Department of Obstetrics and Gynecology, Microarray Facility, Department of Medical Genetics, University of Tuebingen, Tuebingen, Germany
    Cancer Res 66:5278-86. 2006
    ....
  36. doi request reprint ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer--a comparative study of two monoclonal antibodies
    M Braun
    Institute of Pathology, University Hospital of Bonn, Bonn, Germany
    Prostate Cancer Prostatic Dis 15:165-9. 2012
    ..Furthermore, we assessed whether the ERG protein expression is conserved in lymph node and distant PCa metastases...
  37. pmc Simplified detection of microsatellite instability in colorectal cancer without the need for corresponding germline DNA analysis
    M Ebinger
    Department of Haematology and Oncology, Children s Hospital, University of Tubingen, Tubingen, Germany
    J Clin Pathol 59:1114-5. 2006
    ..Thus, the use of the five mononucleotide repeats in combination with the modified assessment technique simplifies the assessment of MSI, while retaining the sensitivity of the Bethesda panel for the detection of high-frequency MSI...
  38. ncbi request reprint Detection of melanoma cells displaying multiple genomic changes in histopathologically negative sentinel lymph nodes
    Anja Ulmer
    Universitäts Hautklinik, Eberhard Karls Universitat, Tubingen, Germany
    Clin Cancer Res 11:5425-32. 2005
    ..We present a novel strategy for detection of melanoma cells in sentinel lymph nodes and confirm their malignant descent by genomic characterization...
  39. ncbi request reprint Morphologic, functional, and metabolic magnetic resonance imaging-guided prostate biopsy in a patient with prior negative transrectal ultrasound-guided biopsies and persistently elevated prostate-specific antigen levels
    Matthias P Lichy
    Department of Urology, Comprehensive Cancer Center Tübingen, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Urology 69:1208.e5-8. 2007
    ..Magnetic resonance imaging-guided prostate biopsy was successfully performed. All specimens taken from the lesion showed a Gleason 5 tubular adenocarcinoma with low proliferative activity...
  40. pmc Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? Immunohistochemical and molecular findings on routinely processed bone marrow biopsy specimens
    H P Horny
    Institute of Pathology, University of Lubeck, D 23538 Lubeck, Germany
    J Clin Pathol 56:575-8. 2003
    ....
  41. ncbi request reprint Increased translocator protein (TSPO) mRNA levels in colon but not in rectum carcinoma
    I Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, Tubingen, Germany
    Eur Surg Res 39:359-63. 2007
    ..TSPO was shown to be overexpressed in malignant tumors and cancer cell lines, correlating with enhanced malignant behavior. The present study analyzed the role of TSPO in patients with colorectal carcinomas...
  42. ncbi request reprint Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma
    Stefan Kruger
    Institute of Pathology, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Oncology 68:269-75. 2005
    ..Our aim was to analyze KIT expression immunohistochemically in renal cell carcinomas (RCCs) and in oncocytomas...
  43. pmc Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1
    Hans Neubauer
    Department of Obstetrics and Gynecology, University of Tuebingen, Calwerstrasse, Germany
    Breast Cancer Res 10:R85. 2008
    ..Breast tumors lacking the estrogen receptor-alpha (ER-alpha) have increased incidence of resistance to therapy and poorer clinical prognosis...
  44. ncbi request reprint [Aleukemic mast cell leukemia (formerly: "malignant mastocytosis"): an extremely rare form of leukemia. A case report and simultaneously a contribution to revised classification of mastocytosis]
    Hans Peter Horny
    Institut fur Pathologie, Medizinische Universität zu Lübeck MUL, Lubeck
    Wien Klin Wochenschr 114:222-8. 2002
    ....
  45. pmc Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers
    Kate Middleton
    National Institute for Medical Research, Mill Hill, London
    J Virol 77:10186-201. 2003
    ..It appears from our work that the presence of such proteins in cells at the epithelial surface allows the severity of the underlying disease to be predicted and that markers of viral gene expression may improve cervical screening...
  46. pmc Life cycle heterogeneity in animal models of human papillomavirus-associated disease
    Woei Ling Peh
    National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    J Virol 76:10401-16. 2002
    ..The persistence of abortive infections caused by CRPV offers advantages for the development of therapeutic vaccines...
  47. ncbi request reprint Aleukemic mast cell leukemia with abnormal immunophenotype and c-kit mutation D816V
    Frank Noack
    Department of Pathology, University of Luebeck, Luebeck, Germany
    Leuk Lymphoma 45:2295-302. 2004
    ..However, additional (but yet unknown) molecular (genetic) defects have to be considered to explain the extremely heterogenous clinical course in these patients...
  48. ncbi request reprint Ph-Chromosome-positive chronic myeloid leukemia with associated bone marrow mastocytosis
    Hermine Agis
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria
    Leuk Res 29:1227-32. 2005
    ..The exact knowledge of the pathology and target-profile of the associated leukemias in SM have important therapeutic implications...
  49. ncbi request reprint Inter-laboratory validation of PCR-based HPV detection in pathology specimens
    Iver Petersen
    Charite Campus Mitte, Institut fur Pathologie, Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Virchows Arch 451:701-16. 2007
    ..The initiative is intended to foster the quality assurance of molecular HPV analysis in pathology and its correlation with morphological changes...
  50. ncbi request reprint KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients
    Andres C Garcia-Montero
    Centro de Investigacion del Cancer, Campus Miguel de Unamuno, 37007 Salamanca, Spain
    Blood 108:2366-72. 2006
    ..These results would support the notion that KIT mutation is a hallmark of adult SM where it targets a pluripotent hematopoietic stem cell, and may contribute to explaining previously observed discrepancies in the literature...
  51. ncbi request reprint [Molecular pathological analysis of neoplastic mast cells with regard to the actual WHO classification of mast cell neoplasias]
    Karl Sotlar
    Institut fur Pathologie, Universitat Tubingen
    Verh Dtsch Ges Pathol 90:227-35. 2006
    ..By establishing methods for the detection of c-kit codon 816 mutations in paraffin-embedded tissues, the pathologist holds a central position in the diagnosis of systemic mastocytoses...
  52. ncbi request reprint Parvovirus B19
    Burkhard D Bültmann
    N Engl J Med 350:2006-7; author reply 2006-7. 2004
  53. ncbi request reprint The European Competence Network on Mastocytosis (ECNM)
    Peter Valent
    Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Austria
    Wien Klin Wochenschr 116:647-51. 2004
    ..In addition, the ECNM is dedicated to provide the best available information about the disease to patients and physicians...
  54. ncbi request reprint Effects of the CD33-targeted drug gemtuzumab ozogamicin (Mylotarg) on growth and mediator secretion in human mast cells and blood basophils
    Maria Theresa Krauth
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Vienna, Austria
    Exp Hematol 35:108-16. 2007
    ..We have recently shown that mast cells (MCs) and basophils (BAs) express CD33. In the present study, we investigated the effects of GO on growth and mediator secretion in MCs and BAs...
  55. ncbi request reprint Reorganization of nuclear domain 10 induced by papillomavirus capsid protein l2
    Luise Florin
    Institute for Medical Microbiology and Hygiene, University of Mainz, Mainz, 55101, Germany
    Virology 295:97-107. 2002
    ..The differential change in protein composition observed provides further evidence to suggest that the ND10-associated proteins are an important interface of viral life cycle and host cell...
  56. ncbi request reprint Mastocytosis: pathology, genetics, and current options for therapy
    Peter Valent
    Department of Internal Medicine I, Medical Univeristy of Vienna, Austria
    Leuk Lymphoma 46:35-48. 2005
    ..Examples include the use of STI571 in patients with SM plus hypereosinophilic syndrome (SM-HES) and the FIPL1/PDGFRA fusion gene target, or chemotherapy for eradication of AML in patients with SM-AML...