- Staphylococcus aureus host cell invasion and post-invasion eventsBhanu Sinha
Institute of Hygiene and Microbiology, University of Wurzburg, Josef Schneider Strasse 2, Bldg E1, D 97080 Wurzburg, Germany
Int J Med Microbiol 300:170-5. 2010..The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin...
- Intracellular Staphylococcus aureus: live-in and let dieMartin Fraunholz
Department of Microbiology, Biocenter, University of Wurzburg, Wurzburg, Germany
Front Cell Infect Microbiol 2:43. 2012..The focus of this review is to present a guide to recent research outlining the variety of intracellular fates of S. aureus...
- Ischemia-reperfusion injury-induced pulmonary mitochondrial damageSebastian Patrick Sommer
Department of Cardiothoracic and Thoracic Vascular Surgery, University Hospital Wurzburg, Wurzburg, Germany
J Heart Lung Transplant 30:811-8. 2011..Impaired mitochondrial integrity predisposes to cellular energy depletion, free radical generation, and cell death. This study analyzed mitochondrial damage induced by warm pulmonary IR...
- Phagolysosomal integrity is generally maintained after Staphylococcus aureus invasion of nonprofessional phagocytes but is modulated by strain 6850Thien Tri Lam
Institute of Hygiene and Microbiology, University of Wurzburg, Josef Schneider Str 2, Bldg E1, 97080 Wurzburg, Germany
Infect Immun 78:3392-403. 2010..Taken together, our data suggest that S. aureus-containing phagolysosomes generally remain functionally intact in nonprofessional phagocytes, thereby contrasting with transmission electron micrographic results...
- SDS interferes with SaeS signaling of Staphylococcus aureus independently of SaePQPhuti E Makgotlho
Institute for Hygiene and Microbiology, University of Wurzburg, Wurzburg, Germany
PLoS ONE 8:e71644. 2013..This suggests that SaeS activity might be directly modulated by structurally non-complex environmental signals, as SDS, which possibly altering its kinase/phosphatase activity. ..
- A point mutation in the sensor histidine kinase SaeS of Staphylococcus aureus strain Newman alters the response to biocide exposureDaniel Schafer
Institute of Hygiene and Microbiology, University of Wurzburg, Wurzburg, Germany
J Bacteriol 191:7306-14. 2009..This may be important for understanding the regulation of virulence in S. aureus...