Neelam Shahani

Summary

Country: Germany

Publications

  1. ncbi Purification of MINUS: A negative regulator of microtubule nucleation in a variety of organisms
    Neelam Shahani
    Department of Neurobiology, University of Osnabruck, Barbarastrasse 11, D 49076 Osnabrück, Germany
    Int J Biol Macromol 39:15-22. 2006
  2. ncbi Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices
    Neelam Shahani
    Department of Neurobiology, University of Osnabruck, 49076 Osnabruck, Germany
    J Neurosci 26:6103-14. 2006
  3. ncbi Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
    Roland Brandt
    Department of Neurobiology, University of Osnabruck, Barbarastrasse 11, D 49076 Osnabrück, Germany
    Biochim Biophys Acta 1739:331-54. 2005
  4. ncbi Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway
    Srinivasa Subramaniam
    Neuroanatomy and Interdisciplinary Center for Neurosciences, University of Heidelberg, D 69120 Heidelberg, Germany
    J Neurosci 25:2838-52. 2005

Detail Information

Publications4

  1. ncbi Purification of MINUS: A negative regulator of microtubule nucleation in a variety of organisms
    Neelam Shahani
    Department of Neurobiology, University of Osnabruck, Barbarastrasse 11, D 49076 Osnabrück, Germany
    Int J Biol Macromol 39:15-22. 2006
    ..Collectively, the data suggest that MINUS belongs to a new class of MT assembly regulators. Sequence information and antibody development will be useful to examine its biological role in a definitive manner...
  2. ncbi Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices
    Neelam Shahani
    Department of Neurobiology, University of Osnabruck, 49076 Osnabruck, Germany
    J Neurosci 26:6103-14. 2006
    ..Furthermore, they demonstrate that targeted expression of tau in hippocampal slices provides a novel model to analyze tau modification and spatiotemporal dynamics of tau-dependent neurodegeneration in an authentic CNS environment...
  3. ncbi Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
    Roland Brandt
    Department of Neurobiology, University of Osnabruck, Barbarastrasse 11, D 49076 Osnabrück, Germany
    Biochim Biophys Acta 1739:331-54. 2005
    ..The review ends with concluding remarks about a general mechanistic model of the role of tau alteration and neuronal degeneration in tauopathies and future perspectives...
  4. ncbi Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway
    Srinivasa Subramaniam
    Neuroanatomy and Interdisciplinary Center for Neurosciences, University of Heidelberg, D 69120 Heidelberg, Germany
    J Neurosci 25:2838-52. 2005
    ..Together, these data demonstrate that IGF-1 can positively and negatively regulate the ERK pathway in the same neuronal cell, and provide new insights into the PI3K/Akt/PKA signaling pathways in IGF-1-mediated neuronal survival...