Janina Seznec

Summary

Affiliation: Hertie-Institute for Clinical Brain Research
Location: Tuebingen, Germany
URL: http://www.xing.com/profile/Janina_Seznec
Summary:
Biochemistry, Molecular Biology, Cell Biology, Oncology, Neuro-Oncology, Glioma, NF-kappaB, p53
Publications:
Seznec J, and Naumann U: Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Novel Signaling Pathways and Genes Controlling Resistance. Cancers 2011 [submitted].

Höring E, Harter PN, Seznec J, Schittenhelm J, Mittelbronn M, Naumann U: The neuropeptide processing enzyme carboxy-peptidase E holds anti-migratory capacity in glioma cells. 2011 [in preparation].

Naumann U, Holm PS, Mantwill K, Seznec J: YB-1 dependent oncolytic adenovirus as a strategy for the treatment of glioma cancer stem cells. DG-GT-Meeting, Munich 2010; Human Gene Therapy 2010; 21(9): 1180.

Seznec J, Silkenstedt B, and Naumann U: Therapeutic effects of the Sp1 inhibitor Mithamycin A in glioblastoma. J Neurooncol. 2011; 101(3): 365-77.

Seznec J, Weit S, Naumann U: Gene expression profile in a glioma cell line resistant to cell death induced by the chimeric tumor suppressor-1 (CTS-1), a dominant-positive variant of p53-the role of NFkappaB. Carcinogenesis. 2010 Mar; 31(3):411-8.

Wirth KG, Wutz G, Kudo NR, Desdouets C, Zetterberg A, Taghybeeglu S, Seznec J, Ducos GM, Ricci R, Firnberg N, Peters JM, Nasmyth K: Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol. 2006 Mar 13; 172(6):847-60.

Publications

  1. pmc Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression
    Karin G Wirth
    Research Institute of Molecular Pathology, A 1030 Vienna, Austria
    J Cell Biol 172:847-60. 2006
  2. doi Gene expression profile in a glioma cell line resistant to cell death induced by the chimeric tumor suppressor-1 (CTS-1), a dominant-positive variant of p53--the role of NFkappaB
    Janina Seznec
    Laboratory of Molecular Neuro Oncology, Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Otfried Muller Strasse 27, 72076 Tubingen, Germany
    Carcinogenesis 31:411-8. 2010

Collaborators

Detail Information

Publications2

  1. pmc Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression
    Karin G Wirth
    Research Institute of Molecular Pathology, A 1030 Vienna, Austria
    J Cell Biol 172:847-60. 2006
    ..Separase depletion in bone marrow causes aplasia and the presumed death of hematopoietic cells other than erythrocytes. Destruction of sister chromatid cohesion by Separase may be a universal feature of mitosis in eukaryotic cells...
  2. doi Gene expression profile in a glioma cell line resistant to cell death induced by the chimeric tumor suppressor-1 (CTS-1), a dominant-positive variant of p53--the role of NFkappaB
    Janina Seznec
    Laboratory of Molecular Neuro Oncology, Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Otfried Muller Strasse 27, 72076 Tubingen, Germany
    Carcinogenesis 31:411-8. 2010
    ....