Research Topics
Species | Michael SeifertSummaryCountry: Germany Publications
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Publications
Parsimonious higher-order hidden Markov models for improved array-CGH analysis with applications to Arabidopsis thalianaMichael Seifert
Department of Molecular Genetics, Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Gatersleben, Germany
PLoS Comput Biol 8:e1002286. 2012..An implementation of parsimonious higher-order HMMs is available as part of the open source Java library Jstacs (www.jstacs.de/index.php/PHHMM)...
Utilizing gene pair orientations for HMM-based analysis of promoter array ChIP-chip dataMichael Seifert
Leibniz Institute of Plant Genetics and Crop Plant Research, Data Inspection Group, Corrensstrasse 3, 06466 Gatersleben, Germany
Bioinformatics 25:2118-25. 2009....
Exploiting prior knowledge and gene distances in the analysis of tumor expression profiles with extended Hidden Markov ModelsMichael Seifert
Department of Molecular Genetics, Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Gatersleben, Germany
Bioinformatics 27:1645-52. 2011..Additional information about the distribution of gene expression levels and distances between adjacent genes on chromosomes should be integrated into the analysis of tumor expression profiles...
Toward the identification and regulation of the Arabidopsis thaliana ABI3 regulonGudrun Mönke
Department of Molecular Genetics, Leibniz Institute of Plant Genetics and Crop Plant Research IPK Corrensstr 3, D 06466 Gatersleben, Germany
Nucleic Acids Res 40:8240-54. 2012..The data strengthen and extend the notion that ABI3 is essential for the protection of embryonic structures from desiccation and raise pertinent questions regarding the specificity of promoter recognition...
Elongation-related functions of LEAFY COTYLEDON1 during the development of Arabidopsis thalianaAstrid Junker
Leibniz Institute of Plant Genetics and Crop Plant Research, Corrensstraße 3, D 06466 Gatersleben, Germany
Plant J 71:427-42. 2012..Furthermore, the data suggest non-embryonic functions for LEC1 during post-germinative etiolation...
MeDIP-HMM: genome-wide identification of distinct DNA methylation states from high-density tiling arraysMichael Seifert
Department of Molecular Genetics, Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Gatersleben, Germany, Institut de Biologie de l Ecole Normale Supérieure, Centre National de la Recherche Scientifique CNRS, UMR8197, Paris, France, Cellular Networks and Systems Biology, Biotechnology Center of the Technical University Dresden, Dresden, Germany and Groningen Bioinformatics Centre, University of Groningen, Groningen, The Netherlands
Bioinformatics 28:2930-9. 2012..Therefore, a method for the identification of more than two methylation states is highly desirable...
Additive inheritance of histone modifications in Arabidopsis thaliana intra-specific hybridsAli M Banaei Moghaddam
Leibniz Institute of Plant Genetics and Crop Plant Research, Corrensstraße 3, 06466 Gatersleben, Germany
Plant J 67:691-700. 2011..In conclusion, intra-species hybridization does not result in gross changes to chromatin modifications...
