Research Topics
| Wolfram BruggerSummaryAffiliation: Schwarzwald-Baar Klinikum Villingen-Schwenningen GmbH Country: Germany Publications
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Detail Information
Publications
EGFR-TKI resistant non-small cell lung cancer (NSCLC): new developments and implications for future treatmentWolfram Brugger
Medical Center II, Department of Hematology Oncology, Schwarzwald Baar Clinic, Academic Teaching Hospital University of Freiburg, Villingen Schwenningen, Germany
Lung Cancer 77:2-8. 2012..g. EGFR and MET) and vertical inhibition by combination of small molecules and antibodies, seem to be more promising and will be the prevailing concepts to overcome secondary EGFR-TKI resistance for the near future...
Neutrophil recovery in elderly breast cancer patients receiving adjuvant anthracycline-containing chemotherapy with pegfilgrastim supportW Brugger
Schwarzwald Baar Clinic Villingen Schwenningen, University of Freiburg, Germany
Crit Rev Oncol Hematol 72:265-9. 2009..0 x 10(9)/L versus approximately 25% of those receiving no pegfilgrastim. In conclusion, cycle 1 pegfilgrastim improved recovery from severe neutropenia in elderly breast cancer patients receiving adjuvant FEC100...
Successful treatment with the fully human antibody panitumumab after a severe infusion reaction with cetuximabWolfram Brugger
Schwarzwald Baar Clinic, Villingen Schwenningen, Teaching Hospital, University of Freiburg, Germany
Tumori 96:473-7. 2010..There are only limited data on the safety and efficacy of panitumumab in patients who experienced severe infusion reactions during cetuximab antibody therapy...
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancerWolfram Brugger
Schwarzwald Baar Klinikum, Academic Teaching Hospital, University of Freiburg, Voehrenbacher Str 23, Villingen Schwenningen, Germany 78050
J Clin Oncol 29:4113-20. 2011..This study included prospective analysis of the prognostic and predictive value of several biomarkers...
Severe idiopathic erythroblastic synartesis: successful treatment with the anti-CD20 monoclonal antibody rituximabGeorgios Papakonstantinou
Medical Center, Department of Hematology Oncology, Schwarzwald Baar Clinic, Academic Teaching Hospital, University of Freiburg, Villingen Schwenningen, Germany
Eur J Haematol 84:547-9. 2010..At a follow-up of 30 months after treatment, the patient is still in continuous complete remission without any further treatment, suggesting that rituximab may induce prolonged remissions and eventually cure in this rare disease...
