Research Topics
Genomes and GenesSpecies | P E H SchwarzSummaryCountry: Germany Publications
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Publications
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analysesTakafumi Tsuchiya
Departments of Medicine and Human Genetics, The University of Chicago, 5841 S Maryland Ave, MC1027, Chicago, IL 60637, USA
Mol Genet Metab 89:174-84. 2006..68 (1.33-2.11), P=0.00001). The pooled and meta-analyses as well as the linkage disequilibrium and haplotype diversity studies suggest a role for genetic variation in CAPN10 affecting risk of T2D in Europeans...
Global Diabetes Survey-An annual report on quality of diabetes carePeter E H Schwarz
Technical University Dresden, Germany Electronic address
Diabetes Res Clin Pract 100:11-8. 2013....- Nonpharmacological interventions for the prevention of type 2 diabetes mellitusPeter E Schwarz
Department for Prevention and Care of Diabetes, Medical Clinic III, University Clinic Carl Gustav Carus at the Technical University Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
Nat Rev Endocrinol 8:363-73. 2012..In this Review, we will discuss these mechanisms and will consider the implications of diabetes prevention for public-health strategy and policy... 
Estimating the cost-effectiveness of lifestyle intervention programmes to prevent diabetes based on an example from Germany: Markov modellingAnne Neumann
Epidemiology and Global Health, Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden
Cost Eff Resour Alloc 9:17. 2011..abstract:..- Systematic review of reviews of intervention components associated with increased effectiveness in dietary and physical activity interventionsColin J Greaves
University of Exeter, Peninsula Medical School, Smeall Building, St Luke s Campus, Magdalen Road, Exeter EX1 2LU, UK
BMC Public Health 11:119. 2011..The aim of this systematic review of reviews was to identify intervention components that are associated with increased change in diet and/or physical activity in individuals at risk of type 2 diabetes... - [Prevention in occupational health care--a societal challenge]Peter E H Schwarz
Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Dresden
Med Klin (Munich) 103:210-6. 2008..This process will be challenging and must be sustainable requiring many partners but resulting in a profitable chance for occupational health care... - Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiativesP E H Schwarz
Division of Endocrinology, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technical University Dresden, Dresden, Germany
Pharmacogenomics J 9:42-8. 2009..Thus, to examine diabetes risk, a more global approach including the design of population-specific experimental strategies should be used, which will be crucial in developing health education and policies in a global health programme... - The European perspective on diabetes prevention: development and Implementation of A European Guideline and training standards for diabetes prevention (IMAGE)Peter E H Schwarz
Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany
Diab Vasc Dis Res 4:353-7. 2007.... - Prevention of type 2 diabetes--lessons we have learnt for implementationP E H Schwarz
IIIo Medical Clinic, Carl Gustav Carus Medical School, Dresden University of Technology, Dresden, Germany
Horm Metab Res 39:636-41. 2007..We focus on the development of a structured prevention management program which will enable implementation of diabetes prevention into clinical practice... - The European perspective of type 2 diabetes prevention: diabetes in Europe--prevention using lifestyle, physical activity and nutritional intervention (DE-PLAN) projectP E H Schwarz
Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
Exp Clin Endocrinol Diabetes 116:167-72. 2008..The DE-PLAN ("Diabetes in Europe - Prevention using Lifestyle, Physical Activity and Nutritional intervention") project, led by the University of Helsinki is currently addressing this major public health concern in Europe... - The European perspective of diabetes preventionP E H Schwarz
Department of Prevention on Care of Type 2 Diabetes, Clinic of Internal Medicine III, Medical Faculty Carl Gustav Carus, Technical University Dresden, Dresden, Germany
Horm Metab Res 40:511-4. 2008..The DPF is taking immediate action to co-ordinate and improve the information flow between all relevant stakeholders to enable more effective communication, so helping to improve the ability to prevent type 2 diabetes in Europe... - [Prevention of type 2 diabetes in Germany--a challenge for health professionals]Peter E H Schwarz
Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden
Med Monatsschr Pharm 30:289-96. 2007..This process will be challenging and time consuming, requiring many partners but resulting in a profitable "health" investment... - Public health implications: translation into diabetes prevention initiatives--four-level public health conceptPeter E H Schwarz
Department for Prevention and Care of Diabetes, Medical Clinic III, University Clinic Carl Gustav Carus at Technical University Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
Med Clin North Am 95:397-407, ix. 2011..A 4-level public health initiative has been initiated that provides guidance for establishing milestones and strategies for such a program... - Prevention of type 2 diabetes: the strategic approach for implementationP E H Schwarz
Division for Prevention and Care of Diabetes Mellitus, Technische Universitat Dresden, Germany
Horm Metab Res 43:907-10. 2011..The use of a global stakeholder network can help to share experiences and build on partner knowledge gained... - Tools for predicting the risk of type 2 diabetes in daily practiceP E H Schwarz
Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany
Horm Metab Res 41:86-97. 2009..We conclude that the FINDRISC tool is currently the best available tool for use in clinical practice in Caucasian populations, but modifications may be required if applied to other ethnic groups... - The Finnish Diabetes Risk Score is associated with insulin resistance and progression towards type 2 diabetesPeter E H Schwarz
Medical Faculty Carl Gustav Carus of Technical University Dresden, Medical Clinic III, Building 10, Room 108, Fetscherstrasse 74, 01309 Dresden, Germany
J Clin Endocrinol Metab 94:920-6. 2009..In this study we evaluated the usefulness of the FINDRISC to predict insulin resistance in a population at increased diabetes risk... - The A98V single nucleotide polymorphism (SNP) in hepatic nuclear factor 1 alpha (HNF-1alpha) is associated with insulin sensitivity and beta-cell functionA Bergmann
Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University, Dresden, Germany
Exp Clin Endocrinol Diabetes 116:S50-5. 2008..The aims of the study was to determine whether two single nucleotide polymorphisms (SNPs) ile27-to-leu and ala98-to-val in the HNF-1alpha gene associate with diabetes, insulin sensitivity as well as beta-cell function... - A more simplified Finnish diabetes risk score for opportunistic screening of undiagnosed type 2 diabetes in a German population with a family history of the metabolic syndromeJ Li
Department of Medicine, Carl Gustav Carus, Technical University Dresden, Dresden, Germany
Horm Metab Res 41:98-103. 2009..The FINDRISC questionnaire can be used to identify undetected diabetes in a German population. The simplified version, the categorical-model, may be a useful alternative for identifying asymptomatic type 2 diabetes... - Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetesA Bergmann
Health Care Centre of Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
Exp Clin Endocrinol Diabetes 116:S56-8. 2008..But some other studies showed that, this association was not significant in Chinese and French . The aim of the current study was to examine whether the associations manifested in a German population with high risk of type 2 diabetes... - Genetic variation of Neurogenin 3 is slightly associated with hyperproinsulinaemia and progression toward type 2 diabetesJ Li
Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
Exp Clin Endocrinol Diabetes 116:178-83. 2008..The aim of the current study was to investigate the relevance of NGN3 variants for the clinical spectrum of diabetes development and disease progressions... - Insulin resistance -- the role of ethnicity: evidence from Caucasian and African cohortsM Reimann
Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
Horm Metab Res 39:853-7. 2007..These factors may be influenced or modified by a central theme: visceral obesity. This mini review will elaborate on these issues illustrated by observations from Caucasian and African cohorts... - The Metabolic Syndrome - a global challenge for preventionP E H Schwarz
Department of Internal Medicine III, Clinic for Endocrinology, Diabetes and Metabolism, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
Horm Metab Res 39:777-80. 2007..A global health strategy has to take into account political, epidemiological, environmental, infrastructural and genetic aspects. The Metabolic Syndrome is not a mystery - it is a clinical paradigm and global challenge... - Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian populationP E H Schwarz
III Medical Clinic Department of Endocrinopathies and Metabolic Diseases, Dresden, Germany
Horm Metab Res 38:447-51. 2006..006) after correction for BMI and age. Our observations suggest that diploid combinations of haplotype in the adiponectin gene promoter region contribute to the genetic risk of T2D in individuals from a German Caucasian population... - The health status of Russian-speaking immigrants in GermanyS Tselmin
Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany
Horm Metab Res 39:858-61. 2007..Nevertheless relevant data concerning migration-related public health care are very scare... - [Prevention of diabetes mellitus: the future of German diabetology]P E H Schwarz
Medizinische Klinik III, Universitatsklinikum Carl Gustav Carus, der Technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
Hamostaseologie 27:13-21. 2007..This guideline also includes the structure of a national prevention program with a prevention manager having a central role in the concept and suggestions for evaluation and quality control... - A simplified Finnish diabetes risk score to predict type 2 diabetes risk and disease evolution in a German populationA Bergmann
Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
Horm Metab Res 39:677-82. 2007..We aimed to evaluate its performance to predict diabetes in a German population and to compare its predictive and detective ability in the same population... - Diabetes prevention--from physiology to implementationP E H Schwarz
Technical University of Dresden, Medical Faculty Carl Gustav Carus, Medical Clinic III, Department of Endocrinopathies and Metabolic Disease, Dresden, Germany
Horm Metab Res 38:460-4. 2006..This process will be challenging and time consuming, requiring many partners but resulting in a profitable "health" investment... - An update on preventive and regenerative therapies in diabetes mellitusM Reimann
Department of Internal Medicine III, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
Pharmacol Ther 121:317-31. 2009..Lastly, important efforts to halt disease progression with emphasis on beta-cell regeneration are presented... - [Prevention of type 2 diabetes in Germany. Ideas, evidence, implementation]Peter E H Schwarz
Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus der technischen Universität Dresden, Fetscherstrasse 74, 01307 Dresden
Med Klin (Munich) 101:730-6. 2006..This guideline also includes the structure of a national prevention program with a prevention manager having a central role in the concept and suggestions for evaluation and quality control... - Circulating very-low-density lipoprotein from subjects with impaired glucose tolerance accelerates adrenocortical cortisol and aldosterone synthesisS Saha
Department of Internal Medicine 3, Carl Gustav Carus Medical School, Technical University of Dresden, Dresden, Germany
Horm Metab Res 45:169-72. 2013..In summary, in vivo modified VLDL are able to promote prediabetic hormonal dysregulation by modulating adrenocortical steroidogenesis via Jak-2-ERK dependent pathway... - Mutations and intronic variants in the HNF-1 beta gene in a group of German and Czech Caucasians with type 2 diabetes mellitus and progressive diabetic nephropathyT Selisko
Department of Internal Medicine III, University Clinic Carl Gustav Carus of the Technical University Dresden, Germany
Exp Clin Endocrinol Diabetes 110:145-7. 2002..The results confirm that the genetic variations in the HNF-1 beta gene would be a very uncommon cause of progressive nephropathy in patients with type 2 diabetes mellitus... - High prevalence of dyslipidemia in the Dresden Jewish populationS Tselmin
Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
Horm Metab Res 39:700-1. 2007 - Development of a diabetes prevention management program for clinical practicePeter E H Schwarz
Department of Internal Medicine, Carl Gustav Carus Medical School, Dresden University of Technology, Germany
Public Health Rep 122:258-63. 2007 - Beyond lowering circulating LDL: apheresis-induced changes of systemic oxidative stress markers by four different techniquesSteffi Kopprasch
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Germany
Atheroscler Suppl 10:34-8. 2009.... - Single whole blood dextran sulfate adsorption favorably affects systemic oxidative balance in lipoprotein apheresis patientsS Kopprasch
Department of Internal Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany
Atheroscler Suppl 14:157-60. 2013..The acute changes of circulating oxidative stress parameters were compared in 16 patients undergoing two different apheresis techniques: plasma lipidfiltration (LF) or whole blood dextran sulfate adsorption (DSA)... - The importance and effect of dietary fiber in diabetes prevention with particular consideration of whole grain productsK Kaline
Medical Faculty Carl Gustav Carus at the Technical University of Dresden, Department of Medicine III, Genetics and Prevention of Diabetes, Dresden, Germany
Horm Metab Res 39:687-93. 2007..A high intake of fruits and vegetables as well as pulses also exerts health-promoting properties. A high-fiber diet also plays an important role in the prevention of obesity and coronary heart diseases... - Congress report from the American Diabetes Association 66th Annual Scientific Sessions in Washington, USAP E H Schwarz
Medizinische Klinik III, , Germany
Exp Clin Endocrinol Diabetes 114:605-10. 2006 - Hypoadiponectinemia is associated with progression toward type 2 diabetes and genetic variation in the ADIPOQ gene promoterPeter E H Schwarz
Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Medical Clinic III, Building 46, Room 10, Fetscherstrasse 74, 01309, Dresden, Germany
Diabetes Care 29:1645-50. 2006..The aim of the current study was to investigate whether ADIPOQ gene variants in the promoter region predict adiponectin levels and type 2 diabetes progression... - Report from the Congress of the American Diabetes Association (ADA): Orlando 2005 - 65th Annual Scientific Sessions in San Diego, CA, USA, June 10th-14th 2005P E H Schwarz
Medizinische Klinik III, , Germany
Exp Clin Endocrinol Diabetes 113:475-9. 2005 - Evaluation of a diabetes management system based on practice guidelines, integrated care, and continuous quality management in a Federal State of Germany: a population-based approach to health care researchUlrike Rothe
Institute for Medical Informatics and Biometrics, Medical Faculty Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
Diabetes Care 31:863-8. 2008..The SDMP was implemented into diabetes contracts between health insurance providers, general practitioners (GPs), and diabetes specialized practitioners (DSPs) unified in the Saxon association of Statutory Health Insurance Physicians... - Elevated fasting glucose levels predicts IGT and diabetes also in middle-age subjectsPeter E H Schwarz
Department of Endocrinopathies and Metabolic Diseases, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Fetscherstrasse 74, Dresden, Germany
Diabetes Res Clin Pract 77:148-50. 2007..We therefore conclude that elevated fasting glucose levels in the "IFG" category predict the development of IGT/diabetes in a middle-age population... - Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patientsJuergen Graessler
Department of Internal Medicine III, Carl Gustav Carus Medical School, Technical University Dresden, Dresden, Germany
PLoS ONE 4:e6261. 2009..The objective of this study was to determine whether hypertension specifically affects the plasma lipidome independently and differently from the effects induced by obesity and insulin resistance... - How should the clinician most effectively prevent type 2 diabetes in the obese person at high risk?Peter E H Schwarz
Department of Public Health, University of Helsinki, Mannerheimintie 172, 00300 Helsinki, Finland
Curr Diab Rep 7:353-62. 2007..The implementation of managed prevention concepts will realistically help to improve the ability to prevent T2D in the public health framework... - An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes: response to Schulze et alPeter E H Schwarz
Diabetes Care 30:e87; author reply e88. 2007 - Protective effect against type 2 diabetes mellitus identified within the ACDC gene in a black South African diabetic cohortAntonel Olckers
Centre for Genome Research, North West University Potchefstroom Campus, Persequor Park, Pretoria, South Africa
Metabolism 56:587-92. 2007..This investigation therefore underscores the genetic heterogeneity at T2D susceptibility loci within the black South African population... - Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibilityMichael N Weedon
Am J Hum Genet 73:1208-12. 2003 - Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjectsNaoko Iwasaki
Diabetes Center, Tokyo Women s Medical University, Tokyo, Japan
Diabetes 52:209-13. 2003..Thus, our results may replicate findings in other studies. They may also indicate new regions of the genome that are involved in the regulation of blood glucose levels or body weight... - Differences and similarities regarding adiponectin investigated in African and Caucasian womenAletta E Schutte
School for Physiology, Nutrition and Consumer Sciences, North West University Potchefstroom Campus, Private Bag X6001, Potchefstroom 2520, South Africa
Eur J Endocrinol 157:181-8. 2007..A second objective was to determine which components of the metabolic syndrome are more closely related to adiponectinemia in both groups... - Validation of a simple clinical diabetes prediction model in a middle-aged, white, German populationJiang Li
Arch Intern Med 167:2528-9. 2007 - Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndromeDavid A Ehrmann
Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
J Clin Endocrinol Metab 87:1669-73. 2002..In addition to its association with insulin levels in African-Americans, the 112/121-haplotype combination was associated with an approximate 2-fold increase in risk of PCOS in both African-Americans and whites...