Lars Schwabe

Summary

Country: Germany

Publications

  1. doi request reprint Stress impairs spatial but not early stimulus-response learning
    Lars Schwabe
    Department of Clinical Physiology, Institute of Psychobiology, University of Trier, 54290 Trier, Germany
    Behav Brain Res 213:50-5. 2010
  2. doi request reprint Stress-induced enhancement of response inhibition depends on mineralocorticoid receptor activation
    Lars Schwabe
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany Electronic address
    Psychoneuroendocrinology 38:2319-26. 2013
  3. doi request reprint β-Adrenergic blockade during reactivation reduces the subjective feeling of remembering associated with emotional episodic memories
    Lars Schwabe
    Douglas Mental Health Institute and Department of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada
    Biol Psychol 92:227-32. 2013
  4. doi request reprint Stress modulates the engagement of multiple memory systems in classification learning
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 32:11042-9. 2012
  5. doi request reprint Preventing the stress-induced shift from goal-directed to habit action with a β-adrenergic antagonist
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 31:17317-25. 2011
  6. doi request reprint Prenatal stress changes learning strategies in adulthood
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Hippocampus 22:2136-43. 2012
  7. doi request reprint Stress effects on memory: an update and integration
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neurosci Biobehav Rev 36:1740-9. 2012
  8. doi request reprint Simultaneous glucocorticoid and noradrenergic activity disrupts the neural basis of goal-directed action in the human brain
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 32:10146-55. 2012
  9. doi request reprint Emotional modulation of the attentional blink: is there an effect of stress?
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Germany
    Emotion 10:283-8. 2010
  10. doi request reprint Stress impairs the reconsolidation of autobiographical memories
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum 44780, Germany
    Neurobiol Learn Mem 94:153-7. 2010

Detail Information

Publications42

  1. doi request reprint Stress impairs spatial but not early stimulus-response learning
    Lars Schwabe
    Department of Clinical Physiology, Institute of Psychobiology, University of Trier, 54290 Trier, Germany
    Behav Brain Res 213:50-5. 2010
    ....
  2. doi request reprint Stress-induced enhancement of response inhibition depends on mineralocorticoid receptor activation
    Lars Schwabe
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany Electronic address
    Psychoneuroendocrinology 38:2319-26. 2013
    ..Our results show that stress may facilitate inhibitory control and that these effects depend on MR functioning. ..
  3. doi request reprint β-Adrenergic blockade during reactivation reduces the subjective feeling of remembering associated with emotional episodic memories
    Lars Schwabe
    Douglas Mental Health Institute and Department of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada
    Biol Psychol 92:227-32. 2013
    ....
  4. doi request reprint Stress modulates the engagement of multiple memory systems in classification learning
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 32:11042-9. 2012
    ..The shift toward "procedural" learning after stress appears to rescue task performance, whereas attempts to engage the "declarative" system disrupt performance...
  5. doi request reprint Preventing the stress-induced shift from goal-directed to habit action with a β-adrenergic antagonist
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 31:17317-25. 2011
    ..Our findings show that the shift from goal-directed to habitual control of instrumental action under stress necessitates noradrenergic activation and could have important clinical implications, particularly for addictive disorders...
  6. doi request reprint Prenatal stress changes learning strategies in adulthood
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Hippocampus 22:2136-43. 2012
    ..Individual differences in acute or chronic stress do not account for these findings. Our data suggest that the engagement of hippocampal and nonhippocampal learning strategies may be influenced by stress very early in life...
  7. doi request reprint Stress effects on memory: an update and integration
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neurosci Biobehav Rev 36:1740-9. 2012
    ....
  8. doi request reprint Simultaneous glucocorticoid and noradrenergic activity disrupts the neural basis of goal-directed action in the human brain
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 32:10146-55. 2012
    ..These findings suggest that concurrent glucocorticoid and noradrenergic activity disrupts the neural bases of goal-directed action and thus renders behavior habitual...
  9. doi request reprint Emotional modulation of the attentional blink: is there an effect of stress?
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Germany
    Emotion 10:283-8. 2010
    ..However, neither stress nor cortisol interacted with the emotionality of the target words. In summary, these findings point to a strong impact of emotional factors on early perceptual experiences...
  10. doi request reprint Stress impairs the reconsolidation of autobiographical memories
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum 44780, Germany
    Neurobiol Learn Mem 94:153-7. 2010
    ..These findings suggest that the effect of stress on memory reconsolidation is opposite to the stress effect on memory consolidation supporting the view that consolidation and reconsolidation are distinct processes...
  11. doi request reprint Concurrent glucocorticoid and noradrenergic activity shifts instrumental behavior from goal-directed to habitual control
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 30:8190-6. 2010
    ..e., habitual). These findings demonstrate that the concerted action of glucocorticoids and noradrenergic activity shifts instrumental behavior from goal-directed to habitual control...
  12. doi request reprint Stress prompts habit behavior in humans
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    J Neurosci 29:7191-8. 2009
    ..Moreover, stress reduced subjects' explicit knowledge of the action-outcome contingencies. These results demonstrate for the first time that stress promotes habits at the expense of goal-directed performance in humans...
  13. doi request reprint Stress, habits, and drug addiction: a psychoneuroendocrinological perspective
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Faculty of Psychology, Department of Cognitive Psychology, Universitaetsstrasse 150, 44780 Bochum, Germany
    Exp Clin Psychopharmacol 19:53-63. 2011
    ..The suggested mechanism encompasses cognitive processes that may contribute to the effects of stress on addictive behavior and could have important implications for the treatment of addiction and the prevention of relapse...
  14. doi request reprint Socially evaluated cold pressor stress after instrumental learning favors habits over goal-directed action
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Psychoneuroendocrinology 35:977-86. 2010
    ..These findings show that stress induced by the socially evaluated cold pressor test can make behavior habitual without affecting processes involved in learning...
  15. doi request reprint Memory formation under stress: quantity and quality
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neurosci Biobehav Rev 34:584-91. 2010
    ..Here, we review stress effects on both quantity and quality of memory and address possible implications of these effects for the understanding of stress-related psychiatric disorders...
  16. pmc New episodic learning interferes with the reconsolidation of autobiographical memories
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    PLoS ONE 4:e7519. 2009
    ..These results suggest that new learning impedes the reconsolidation of neutral autobiographical memories...
  17. doi request reprint Emotional modulation of the attentional blink: the neural structures involved in capturing and holding attention
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neuropsychologia 49:416-25. 2011
    ....
  18. doi request reprint Stress disrupts context-dependent memory
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum 44780, Germany
    Learn Mem 16:110-3. 2009
    ..Stress administered prior to encoding abolished the context-dependent memory enhancement found in the control group. Thus, these findings represent the first demonstration of impaired context-dependent memory following stress...
  19. doi request reprint Stress increases behavioral resistance to extinction
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, 44780 Bochum, Germany
    Psychoneuroendocrinology 36:1287-93. 2011
    ..Overall learning curves remained unaffected. Thus, the present findings suggest that stress increases the resistance of behavior to extinction. The cause of the behavioral persistence after stress may be its habitual form...
  20. doi request reprint Corticosteroids operate as a switch between memory systems
    Lars Schwabe
    University of Trier, Germany
    J Cogn Neurosci 22:1362-72. 2010
    ....
  21. doi request reprint The context counts: congruent learning and testing environments prevent memory retrieval impairment following stress
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Cogn Affect Behav Neurosci 9:229-36. 2009
    ..These results suggest that the detrimental effects of stress on memory retrieval can be abolished when a distinct learning context is reinstated at test...
  22. doi request reprint Learning under stress impairs memory formation
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neurobiol Learn Mem 93:183-8. 2010
    ..These findings show a memory impairing effect of learning under stress in humans and challenge some assumptions of current theories about the impact of stress around the time of learning on memory formation...
  23. doi request reprint A combination of high stress-induced tense and energetic arousal compensates for impairing effects of stress on memory retrieval in men
    Andreas Boehringer
    Department of Clinical Physiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Stress 13:444-53. 2010
    ..This finding could help to explain some of the discrepancies in the literature on stress and memory...
  24. doi request reprint Opposite effects of noradrenergic arousal on amygdala processing of fearful faces in men and women
    Lars Schwabe
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Neuroimage 73:1-7. 2013
    ..These sex differences may represent a biological mechanism that contributes to the differential prevalence of fear-related disorders in men and women...
  25. doi request reprint Neural signature of reconsolidation impairments by propranolol in humans
    Lars Schwabe
    Douglas Mental Health Institute and Department of Psychiatry, McGill University, Montreal, QC, Canada
    Biol Psychiatry 71:380-6. 2012
    ..Here, we asked whether a β-adrenergic receptor antagonist might interfere with the reconsolidation of emotional episodic memories and what brain mechanisms are involved in these effects...
  26. doi request reprint Intranasal insulin attenuates the hypothalamic-pituitary-adrenal axis response to psychosocial stress
    Andreas Bohringer
    Department of Clinical Physiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Psychoneuroendocrinology 33:1394-400. 2008
    ..Our data show that a single intranasal insulin administration effectively lowers stress-induced HPA axis responsiveness. Intranasal insulin may offer a therapeutic potential to prevent hyperactivity of the HPA system...
  27. doi request reprint Chronic stress modulates the use of spatial and stimulus-response learning strategies in mice and man
    Lars Schwabe
    Division of Clinical Physiology, Institute of Psychobiology, University of Trier, Germany
    Neurobiol Learn Mem 90:495-503. 2008
    ..Learning performance was unaffected by the chronic stress level. We conclude that one consequence of chronic stress is the shift to more rigid stimulus-response learning, that is accompanied by changes in motivational factors in mice...
  28. doi request reprint Effects of pre-learning stress on memory for neutral, positive and negative words: Different roles of cortisol and autonomic arousal
    Lars Schwabe
    Department of Clinical Physiology, Institute of Psychobiology, University of Trier, Johanniterufer, 54294 Trier, Germany
    Neurobiol Learn Mem 90:44-53. 2008
    ..negative words...
  29. doi request reprint Modulation of spatial and stimulus-response learning strategies by exogenous cortisol in healthy young women
    Lars Schwabe
    Department of Clinical Physiology, Institute of Psychobiology, University of Trier, Johanniterstrasse 15, 52490 Trier, Germany
    Psychoneuroendocrinology 34:358-66. 2009
    ..Taking into account this dual action of GCs will contribute to a better understanding of stress (hormone) effects on learning and memory...
  30. doi request reprint Stress effects on declarative memory retrieval are blocked by a beta-adrenoceptor antagonist in humans
    Lars Schwabe
    Department of Clinical Physiology, University of Trier, Johanniterufer 15, 54294 Trier, Germany
    Psychoneuroendocrinology 34:446-54. 2009
    ..Procedural memory retrieval and the retrieval of neutral verbal material appear to be less susceptible to stress...
  31. ncbi request reprint Cardiovascular reactivity to mental stress is not affected by alpha2-adrenoreceptor activation or inhibition
    Christine Philippsen
    Division of Clinical Physiology, Graduate School of Psychobiology, University of Trier, Johanniterufer 15, 54290, Trier, Germany
    Psychopharmacology (Berl) 190:181-8. 2007
    ..It has been postulated that cardiovascular reactivity to mental stress varies with tonic central sympathetic nervous system activity, but pharmacological evidence is missing...
  32. doi request reprint Updating of episodic memories depends on the strength of new learning after memory reactivation
    Sonja Wichert
    Department of Cognitive Psychology, Institute of Cognitive Neuroscience, Ruhr University Bochum, Bochum, Germany
    Behav Neurosci 127:331-8. 2013
    ....
  33. doi request reprint Stress disrupts response memory retrieval
    Friederike M Guenzel
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany
    Psychoneuroendocrinology 38:1460-5. 2013
    ..Moreover, high cortisol concentrations were associated with reduced S-R memory. These findings indicate that stress may affect memory retrieval processes in humans beyond hippocampal 'declarative' memory...
  34. doi request reprint Stress-induced modulation of instrumental behavior: from goal-directed to habitual control of action
    Lars Schwabe
    Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Northrhine Westfalia, Germany
    Behav Brain Res 219:321-8. 2011
    ..Although generally adaptive, these changes in the control of instrumental action under stress may promote dysfunctional behaviors and the development of psychiatric disorders such as addiction...
  35. ncbi request reprint Dehydration does not influence cardiovascular reactivity to behavioural stress in young healthy humans
    Lars Schwabe
    Department of Clinical Physiology, Institute of Psychobiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Clin Physiol Funct Imaging 27:291-7. 2007
    ..The effects on heart rate reactivity are small. However, stress-induced parasympathetic withdrawal may be fortified during dehydration in females, which suggests controlling for water intake when studying such responses...
  36. doi request reprint HPA axis activation by a socially evaluated cold-pressor test
    Lars Schwabe
    Department of Clinical Physiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
    Psychoneuroendocrinology 33:890-5. 2008
    ..These findings indicate that the incorporation of social-evaluative elements increases HPA axis responses to the CPT. The SECPT can serve as a tool for future stress research...
  37. doi request reprint On the relationship between learning strategy and feedback processing in the weather prediction task--Evidence from event-related potentials
    Martina Rustemeier
    Institute of Cognitive Neuroscience, Dept of Neuropsychology, Ruhr University Bochum, Universitaetsstrasse 150, D 44801 Bochum, Germany
    Neuropsychologia 51:695-703. 2013
    ..Our findings provide evidence for different neural mechanisms of feedback processing in declarative and non-declarative learning. This difference emerges at later stages of feedback processing, after the typical time window of the FRN...
  38. doi request reprint Reactivation, interference, and reconsolidation: are recent and remote memories likewise susceptible?
    Sonja Wichert
    Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Behav Neurosci 125:699-704. 2011
    ..These findings show that retrieval and interference have opposite effects on memory that depend on the remoteness of the memories and raise the question under which conditions reconsolidation effects occur in human memory...
  39. doi request reprint Mineralocorticoid receptor blockade prevents stress-induced modulation of multiple memory systems in the human brain
    Lars Schwabe
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany Electronic address
    Biol Psychiatry 74:801-8. 2013
    ....
  40. doi request reprint Stress and multiple memory systems: from 'thinking' to 'doing'
    Lars Schwabe
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Bochum, Germany
    Trends Cogn Sci 17:60-8. 2013
    ..We argue that, despite being generally adaptive, this stress-induced shift towards 'habit' memory may, in vulnerable individuals, be a risk factor for psychopathology...
  41. doi request reprint Changing memories after reactivation: a one-time opportunity?
    Sonja Wichert
    Department of Cognitive Psychology, Ruhr University Bochum, Germany
    Neurobiol Learn Mem 99:38-49. 2013
    ..These findings may have important implications for novel treatment approaches that aim for modification of unwanted memories during reconsolidation...
  42. doi request reprint Sex differences in stress effects on response and spatial memory formation
    Friederike M Guenzel
    Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany International Graduate School of Neuroscience IGSN, Ruhr University Bochum, Universitaetsstrasse 150, 44801 Bochum, Germany
    Neurobiol Learn Mem 109:46-55. 2014
    ..Moreover, our data underline that participants' sex may play a critical role in the impact of stress on multiple memory systems. ..