P J Schuler
Schuler P, Trellakis S, Greve J, Bas M, Bergmann C, Bölke E, et al
. In vitro chemosensitivity of head and neck cancer cell lines. Eur J Med Res. 2010;15:337-44 pubmed
..Determined in vitro chemosensitivity serves as a baseline for further experimental approaches aiming to modulate chemoresistance in HNSCC with potential clinical significance. ..
Schuler P, Heikaus S, Friebe Hoffmann U, Hoffmann T, Greve J, Klenzner T, et al
. [Breast cancer metastases in the head and neck region]. HNO. 2010;58:859-65 pubmed publisher
..We believe that the loss of steroid receptor expression contributed to tumor resistance to endocrine therapy. Moreover, this receptor loss hindered the pathologist from confirming the diagnosis of metastases at very unusual sites...
Schuler P, Bendszus M, Kuehnel S, Wagner S, Hoffmann T, Goldbrunner R, et al
. Urokinase plasminogen activator, uPAR, MMP-2, and MMP-9 in the C6-glioblastoma rat model. In Vivo. 2012;26:571-6 pubmed
..The mean tumor volume 23 days after implantation was 3.2 mm3. uPA, uPAR, MMP-2 and MMP-9 play an important role in GBM growth. Blockade of uPA and interruption of the proteolytic cascade could become a useful tool in the therapy of GBM. ..