E Schonherr

Summary

Country: Germany

Publications

  1. ncbi request reprint Decorin affects endothelial cells by Akt-dependent and -independent pathways
    E Schonherr
    Institute of Physiological Chemistry Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    Ann N Y Acad Sci 973:149-52. 2002
  2. ncbi request reprint Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1)
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, Munster, D 48149 Germany
    J Biol Chem 276:40687-92. 2001
  3. ncbi request reprint Matrix metalloproteinase expression by endothelial cells in collagen lattices changes during co-culture with fibroblasts and upon induction of decorin expression
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Waldeyerstrasse 15, D 48149 Munster, Germany
    J Cell Physiol 187:37-47. 2001
  4. pmc Extracellular matrix and cytokines: a functional unit
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistruy, University of Munster, Germany
    Dev Immunol 7:89-101. 2000
  5. ncbi request reprint Lipoprotein lipase-mediated interactions of small proteoglycans and low-density lipoproteins
    E Schonherr
    Institutes of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Eur J Cell Biol 79:689-96. 2000
  6. ncbi request reprint Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices
    E Schonherr
    Department of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Eur J Cell Biol 78:44-55. 1999
  7. ncbi request reprint Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Waldeyerstrasse 15, Munster, D 48149, Germany
    Arch Biochem Biophys 355:241-8. 1998
  8. ncbi request reprint Different usage of the glycosaminoglycan attachment sites of biglycan
    H Kresse
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    J Biol Chem 276:13411-6. 2001
  9. ncbi request reprint Critical role of glutamate in a central leucine-rich repeat of decorin for interaction with type I collagen
    H Kresse
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    J Biol Chem 272:18404-10. 1997
  10. pmc Modulation of collagen gel contraction by decorin
    K Bittner
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Biochem J 314:159-66. 1996

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Decorin affects endothelial cells by Akt-dependent and -independent pathways
    E Schonherr
    Institute of Physiological Chemistry Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    Ann N Y Acad Sci 973:149-52. 2002
    ..Thus, the matrix proteoglycan decorin is a signaling molecule in ECs that affects cell survival by Akt-dependent and -independent pathways...
  2. ncbi request reprint Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1)
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, Munster, D 48149 Germany
    J Biol Chem 276:40687-92. 2001
    ..These results show that decorin is a signaling molecule in sprouting endothelial cells where it acts via different pathways, one of them involving Akt/protein kinase B...
  3. ncbi request reprint Matrix metalloproteinase expression by endothelial cells in collagen lattices changes during co-culture with fibroblasts and upon induction of decorin expression
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Waldeyerstrasse 15, D 48149 Munster, Germany
    J Cell Physiol 187:37-47. 2001
    ..hy 926 cells for a finely tuned induction of selected MMPs which are involved in angiogenesis whereas the up-regulation of MMPs does not lead to the degradation of the responsible proteoglycan...
  4. pmc Extracellular matrix and cytokines: a functional unit
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistruy, University of Munster, Germany
    Dev Immunol 7:89-101. 2000
    ....
  5. ncbi request reprint Lipoprotein lipase-mediated interactions of small proteoglycans and low-density lipoproteins
    E Schonherr
    Institutes of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Eur J Cell Biol 79:689-96. 2000
    ..It could not be ruled out, however, that a small proportion of the complexes is also taken up by the small proteoglycan receptor...
  6. ncbi request reprint Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices
    E Schonherr
    Department of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Eur J Cell Biol 78:44-55. 1999
    ..Thus, decorin expression seems to be of special importance for the survival of EA.hy 926 cells as well as for cord and tube formation in this angiogenesis model...
  7. ncbi request reprint Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Waldeyerstrasse 15, Munster, D 48149, Germany
    Arch Biochem Biophys 355:241-8. 1998
    ..Thus, decorin may play a biological role in storing this cytokine temporarily in the extracellular matrix and in thereby modulating an interaction of TGF-beta with its signaling receptors...
  8. ncbi request reprint Different usage of the glycosaminoglycan attachment sites of biglycan
    H Kresse
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    J Biol Chem 276:13411-6. 2001
    ..It is shown additionally that biglycan expressed in 293 cells may still contain the propeptide sequence and may carry heparan sulfate chains as well as sulfated N-linked oligosaccharides...
  9. ncbi request reprint Critical role of glutamate in a central leucine-rich repeat of decorin for interaction with type I collagen
    H Kresse
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, D 48149 Munster, Germany
    J Biol Chem 272:18404-10. 1997
    ..These data suggest that a major collagen-binding site of decorin is located within the sixth leucine-rich repeat and that glutamate-180 within this repeat is of special importance for ionic interactions between the two matrix components...
  10. pmc Modulation of collagen gel contraction by decorin
    K Bittner
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Germany
    Biochem J 314:159-66. 1996
    ..It is therefore unlikely, that the effect of decorin on collagen-gel retraction is brought about solely by glycosaminoglycan-glycosaminoglycan interactions...
  11. pmc Differences in decorin expression by papillary and reticular fibroblasts in vivo and in vitro
    E Schonherr
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Federal Republic of Germany
    Biochem J 290:893-9. 1993
    ..These results further show that fibroblasts from different layers of the dermis have a specific pattern of synthesis of small chondroitin sulphate/dermatan sulphate proteoglycans, and they also maintain these patterns in cell culture...
  12. ncbi request reprint Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin
    L Schaefer
    Department of Internal Medicine, University of Munster, Munster, Germany
    FASEB J 15:559-61. 2001
    ..They could thereby counteract the vicious circle being characterized by increased TGF-b production and increased matrix deposition in diabetic nephropathy...
  13. ncbi request reprint Proteoglycans of the extracellular matrix and growth control
    H Kresse
    Institute of Physiological Chemistry and Pathobiochemistry, University of Munster, Munster, Germany
    J Cell Physiol 189:266-74. 2001
    ....