Research Topics
Species | E D SchomburgSummaryCountry: Germany Publications
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Detail Information
Publications
Bistable characteristics of motoneurone activity during DOPA induced fictive locomotion in spinal catsE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Neurosci Res 26:47-56. 1996..Motoneurones would not require sustained excitatory input from the rhythm generator during their active phase but a short-lasting initial excitation and a terminating inhibition...
Rhythmic phrenic, intercostal and sympathetic activity in relation to limb and trunk motor activity in spinal catsE D Schomburg
Institute of Physiology, University of Gottingen, Humboldtallee 23, Germany
Neurosci Res 46:229-40. 2003..The findings indicate that during fictive spinal locomotion the activity of spinal rhythm generators for locomotion also projects onto respiratory and sympathetic spinal neurones...
Only minor spinal motor reflex effects from feline group IV muscle nociceptorsEike D Schomburg
Institute of Physiology, University of Gottingen, Humboldtallee 23, D 37073 Gottingen, Germany
Neurosci Res 44:213-223. 2002..It is concluded that the main functional meaning of group IV muscle afferents, which respond preferentially with a higher threshold to mechanical stimuli, is probably less related to reflex motor control than that of group III afferents...
Nociceptive reflexes evoked by TTX-resistant C-fibre afferents and their sensitivity to opioids in the catE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Acta Physiol Pharmacol Bulg 26:193-6. 2001..A distinct part of the opioid action on nociceptive reflex pathways of the FRA-type and of the non-FRA-type was evidently exerted via C-fibres...
Phrenic, intercostal and sympathetic activity related to fictive locomotor activity of limb muscles in spinal catsE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Acta Physiol Pharmacol Bulg 26:151-4. 2001..The findings indicate that during fictive spinal locomotion the activity of spinal rhythm generators for locomotion irradiates onto respiratory and sympathetic spinal neurones...
Parallel nociceptive reflex pathways with negative and positive feedback functions to foot extensors in the catE D Schomburg
Institute of Physiology, University of Gottingen, D 37073 Gottingen, Germany
J Physiol 536:605-13. 2001..e. it mediates a positive feedback...
Nociceptive input to spinal interneurones in reflex pathways from group II muscle afferents in catsE D Schomburg
Department of Physiology, University of Gottingen, Humboldtallee 23, D 37073 Gottingen, Germany
Neurosci Res 38:447-50. 2000..The effects evoked by selective activation of C fibres, after A-delta fibres had been blocked by TTX, were similar to those obtained before TTX application...
Nociceptive input to ascending tract neurones forwarding information from low threshold cutaneous and muscle afferents in catsE D Schomburg
Department of Physiology, Goteborg University, Sweden
Neurosci Res 38:117-20. 2000..Similar effects were evoked by selective actions of C-fibres when A-delta fibres were blocked by TTX...
Contribution of TTX-resistant C-fibres and Adelta-fibres to nociceptive flexor-reflex and non-flexor-reflex pathways in catsE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Neurosci Res 37:277-87. 2000..The results revealed that both Adelta- and C-fibres contributed to nociceptive FRA and non-FRA reflex pathways...
Contribution of group III and IV muscle afferents to multisensorial spinal motor control in catsE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Neurosci Res 33:195-206. 1999..Pathophysiologically, the observed convergence may aggravate muscle weakness and atrophy of muscles induced by group III and IV muscle afferents...
Comparative analysis of L-DOPA actions on nociceptive and non-nociceptive spinal reflex pathways in the catE D Schomburg
Institute of Physiology, University of Gottingen, Germany
Neurosci Res 31:307-16. 1998..Thus, mainly excitatory FRA pathways, irrespective of a nociceptive or non-nociceptive origin, are under strong depressive dopaminergic influences. These effects are similar to those evoked by opioids...
A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neuronesE Jankowska
Department of Physiology, Goteborg University, Sweden
J Physiol 510:513-25. 1998....
Role of L-DOPA in spinal nociceptive reflex activity: higher sensitivity of Aδ versus C fibre-evoked nociceptive reflexes to L-DOPAE D Schomburg
Institute of Physiology, University of Gottingen, Gottingen, Germany
Physiol Res 60:701-3. 2011..Therefore, it can be assumed that L-DOPA, like opioids, preferentially blocks the transmission in nociceptive reflex pathways from Adelta-fibres...
Acute muscle inflammation enhances the monosynaptic reflexes and c-fos expression in the feline spinal cordEike D Schomburg
Zentrum Physiologie und Pathophysiologie, Universitat Gottingen, Humboldtallee 23, D 37073 Gottingen, Germany
Eur J Pain 11:579-86. 2007....
Dopamine and the spinal cord in restless legs syndrome: does spinal cord physiology reveal a basis for augmentation?Walter Paulus
Department of Clinical Neurophysiology, University of Gottingen, Robert Koch Str 40, 37075 Gottingen, Germany
Sleep Med Rev 10:185-96. 2006..In particular, we propose that the differential effects of l-DOPA and opioids on early and late flexor reflexes may be linked to the phenomenon of augmentation...
alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junctionM S Sons
Center for Physiology and Pathophysiology, Georg August University, Humboldtallee 23, 37073 Gottingen, Germany
Neuroscience 138:433-46. 2006..Our data suggest that alpha-neurexins are required for efficient neurotransmitter release at neuromuscular junctions, and that they may perform a role in the molecular mechanism of synaptic homeostasis at these peripheral synapses...
In vivo measurement of conduction velocities in afferent and efferent nerve fibre groups in miceH Steffens
Physiological Institute, University of Gottingen, Gottingen, Germany
Physiol Res 61:203-14. 2012..The results are useful as references for further electrophysiological investigations particularly in genetically modified mice with myelination changes...
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in micePetra May
Zentrum für Neurowissenschaften, University of Freiburg, Albertstrabetae 23, 79104 Freiburg, Germany
Mol Cell Biol 24:8872-83. 2004..Together, these findings suggest that LRP1, like other ApoE receptors, can modulate synaptic transmission in the brain...
