Enno Schmidt

Summary

Country: Germany

Publications

  1. doi request reprint Pemphigoid diseases
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Lancet 381:320-32. 2013
  2. doi request reprint Clinical features and practical diagnosis of bullous pemphigoid
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Immunol Allergy Clin North Am 32:217-32, v. 2012
  3. pmc Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
    Hans Peter Tony
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Wurzburg, Klinikstr 6 8, 97070 Wurzburg, Germany
    Arthritis Res Ther 13:R75. 2011
  4. doi request reprint Research in practice: diagnosis of subepidermal autoimmune bullous disorders
    Enno Schmidt
    Department of Dermatology, Allergy and Venereology, University of Lubeck, Germany
    J Dtsch Dermatol Ges 7:296-300. 2009
  5. doi request reprint [Optimizing therapy in patients with severe autoimmune blistering skin diseases]
    E Schmidt
    Klinik fur Dermatologie, Allergologie und Venerologie, Universitat zu Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Hautarzt 60:633-40. 2009
  6. doi request reprint Clinical features and practical diagnosis of bullous pemphigoid
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Dermatol Clin 29:427-38, viii-ix. 2011
  7. doi request reprint Apoptosis in pemphigus
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Autoimmun Rev 8:533-7. 2009
  8. doi request reprint Rituximab in severe pemphigus
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Ann N Y Acad Sci 1173:683-91. 2009
  9. doi request reprint Immunoadsorption in dermatology
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23560, Lubeck, Germany
    Arch Dermatol Res 302:241-53. 2010
  10. doi request reprint Modern diagnosis of autoimmune blistering skin diseases
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Autoimmun Rev 10:84-9. 2010

Detail Information

Publications55

  1. doi request reprint Pemphigoid diseases
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Lancet 381:320-32. 2013
    ..In this Seminar we discuss the clinical range, diagnostic criteria, diagnostic assay systems, and treatment options for this group of diseases...
  2. doi request reprint Clinical features and practical diagnosis of bullous pemphigoid
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Immunol Allergy Clin North Am 32:217-32, v. 2012
    ..Diagnosis of BP critically relies on immunopathologic examinations including direct immunofluorescence microscopy and detection of serum autoantibodies by indirect immunofluorescence microscopy or BP180-ELISA...
  3. pmc Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
    Hans Peter Tony
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Wurzburg, Klinikstr 6 8, 97070 Wurzburg, Germany
    Arthritis Res Ther 13:R75. 2011
    ....
  4. doi request reprint Research in practice: diagnosis of subepidermal autoimmune bullous disorders
    Enno Schmidt
    Department of Dermatology, Allergy and Venereology, University of Lubeck, Germany
    J Dtsch Dermatol Ges 7:296-300. 2009
    ....
  5. doi request reprint [Optimizing therapy in patients with severe autoimmune blistering skin diseases]
    E Schmidt
    Klinik fur Dermatologie, Allergologie und Venerologie, Universitat zu Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Hautarzt 60:633-40. 2009
    ..The present review focuses on efficacy, adverse events, treatment protocols, and mechanisms of action of IVIG, immunoadsorption, and rituximab in the treatment of severe and/or refractory patients with bullous autoimmune diseases...
  6. doi request reprint Clinical features and practical diagnosis of bullous pemphigoid
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Dermatol Clin 29:427-38, viii-ix. 2011
    ..Diagnosis of BP critically relies on immunopathologic examinations including direct immunofluorescence microscopy and detection of serum autoantibodies by indirect immunofluorescence microscopy or BP180-ELISA...
  7. doi request reprint Apoptosis in pemphigus
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Autoimmun Rev 8:533-7. 2009
    ..Taken together, signalling events leading to apoptosis including activation of executioner caspases are not required but may participate in the cellular response to pemphigus autoantibodies leading to acantholysis...
  8. doi request reprint Rituximab in severe pemphigus
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Ann N Y Acad Sci 1173:683-91. 2009
    ..Here, we review mechanisms of action, different treatment protocols, clinical responses, and the safety profile of rituximab...
  9. doi request reprint Immunoadsorption in dermatology
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23560, Lubeck, Germany
    Arch Dermatol Res 302:241-53. 2010
    ..In addition, an overview of the available IA systems and treatment protocols is provided and guidelines of a recent consensus of German, Austrian, and Swiss experts for the use of IA in autoimmune bullous diseases are summarized...
  10. doi request reprint Modern diagnosis of autoimmune blistering skin diseases
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Autoimmun Rev 10:84-9. 2010
    ..The detection of serum autoantibodies during the course of the disease may thus be helpful in guiding treatment decisions in these patients...
  11. pmc The diagnosis and treatment of autoimmune blistering skin diseases
    Enno Schmidt
    Exzellenzzentrum für Entzündungsmedizin, Klinik fur Dermatologie, Allergologie und Venerologie, Universitat zu Lubeck
    Dtsch Arztebl Int 108:399-405, I-III. 2011
    ....
  12. doi request reprint Diagnosis and treatment of patients with autoimmune bullous disorders in Germany
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Dermatol Clin 29:663-71. 2011
    ..Treatment and diagnostic costs are covered by the health insurances when applied according to published expert recommendations...
  13. doi request reprint Novel ELISA systems for antibodies to desmoglein 1 and 3: correlation of disease activity with serum autoantibody levels in individual pemphigus patients
    Enno Schmidt
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Exp Dermatol 19:458-63. 2010
    ..In conclusion, the use of the ectodomains of Dsg 3 and 1 as target antigens expressed in a human cell line resulted in sensitive and specific ELISA systems for both diagnosis and monitoring of PV and PF...
  14. pmc Pathogenicity of autoantibodies in anti-p200 pemphigoid
    Katerina Vafia
    Department of Dermatology, University of Luebeck, Luebeck, Germany
    PLoS ONE 7:e41769. 2012
    ..Further studies are needed to identify the pathogenically relevant autoantigen in anti-p200 pemphigoid...
  15. ncbi request reprint Enzyme-linked immunosorbent assay using multimers of the 16th non-collagenous domain of the BP180 antigen for sensitive and specific detection of pemphigoid autoantibodies
    Cassian Sitaru
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    Exp Dermatol 16:770-7. 2007
    ..In conclusion, the use of tetrameric NC16A in ELISA results in a sensitive and specific tool for diagnosis and monitoring of BP and PG...
  16. doi request reprint Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen
    Misa Hirose
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, Lübeck D 23538, Germany
    J Autoimmun 39:304-14. 2012
    ..Of note, EndoS was shown to hydrolyze already in vivo-bound pathogenic autoantibodies. In addition, EndoS treatment decreased lesional expression of activating FcγRs while increasing FcγRIIB expression...
  17. ncbi request reprint Autoimmune subepidermal blistering diseases in Uganda: correlation of autoantibody class with age of patients
    Grace K Mulyowa
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Int J Dermatol 45:1047-52. 2006
    ..No data are available on the incidence and immunoreactivity of autoimmune subepidermal blistering skin diseases in East Africa...
  18. doi request reprint Transition from pemphigus foliaceus to bullous pemphigoid: intermolecular B-cell epitope spreading without IgG subclass shifting
    Andreas Recke
    Department of Dermatology at University of Lübeck, Ratzeburger Allee 160, Lubeck 23538, Germany
    J Am Acad Dermatol 61:333-6. 2009
    ..Of interest, although the autoimmune response clearly shifted with regard to the target antigens, the patient's autoantibodies against desmosomal and hemidesmosomal components showed the same IgG subclass distribution...
  19. doi request reprint Sensitive and specific assays for routine serological diagnosis of epidermolysis bullosa acquisita
    Lars Komorowski
    Institute of Experimental Immunology, EUROIMMUN AG, Luebeck, Germany
    J Am Acad Dermatol 68:e89-95. 2013
    ..Epidermolysis bullosa acquisita (EBA) is a severe autoimmune subepidermal blistering disease characterized by autoantibodies against the N-terminal collagenous domain (NC1) of type VII collagen (Col VII)...
  20. doi request reprint Identification of quantitative trait loci in experimental epidermolysis bullosa acquisita
    Ralf J Ludwig
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Invest Dermatol 132:1409-15. 2012
    ..This more detailed insight into the pathogenesis of EBA may eventually lead to new treatment strategies for EBA and other autoantibody-mediated diseases...
  21. doi request reprint Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus
    Christian Probst
    Department of Immunobiochemical Research, Institute for Experimental Immunology affiliated to EUROIMMUN AG, Lubeck, Germany
    Clin Chim Acta 410:13-8. 2009
    ..A sensitive and specific detection system for envoplakin/periplakin-specific autoantibodies is not yet available...
  22. doi request reprint Repetitive immunization breaks tolerance to type XVII collagen and leads to bullous pemphigoid in mice
    Misa Hirose
    Department of Dermatology, University of Lubeck, Lübeck D 23538, Germany
    J Immunol 187:1176-83. 2011
    ....
  23. ncbi request reprint Scarring autoimmune bullous disease in a Ugandan patient with autoantibodies to BP180, BP230, and laminin 5
    Grace K Mulyowa
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    J Am Acad Dermatol 54:S43-6. 2006
    ..Here, we describe a scarring mucocutaneous variant of an autoimmune blistering skin disorder that extends the current clinical and immunopathologic spectrum of this group of diseases...
  24. ncbi request reprint Localisation of bullous pemphigoid antigen 180 (BP180) in cultured human keratinocytes: functionally relevant modification by calcium
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Josef Schneider Str 2, 97080 Wurzburg, Germany
    Arch Dermatol Res 298:283-90. 2006
    ..Our data indicate that the Ca(2+)-modulated expression of BP180 is functionally relevant. This finding sheds further light on the complex pathomechanism in blister formation of BP180-related autoimmune blistering skin diseases...
  25. doi request reprint Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction
    Unni Krishna S R L Samavedam
    Excellence Cluster Inflammation at Interfaces, Schleswig Holstein, Germany Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    J Autoimmun 40:74-85. 2013
    ..We here identified a novel anti-inflammatory pathway in an organ-specific autoimmune disease. Modulation of this IL-1ra pathway by classical IL-6 signalling demonstrates anti-inflammatory and protective activities of IL-6 in vivo...
  26. ncbi request reprint Treatment of bullous pemphigoid with dapsone, methylprednisolone, and topical clobetasol propionate: a retrospective study of 62 cases
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Germany
    Cutis 76:205-9. 2005
    ..Our data suggest that dapsone used in combination with systemic and topical corticosteroids may be a relatively safe and effective treatment option for BP...
  27. doi request reprint Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Germany
    J Pathol 228:8-19. 2012
    ..Our findings both genetically and functionally identify a novel disease-related molecule, FcγRIV, in an autoantibody-mediated disorder, which may be of importance for the development of novel targeted therapies...
  28. doi request reprint Rituximab in treatment-resistant autoimmune blistering skin disorders
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Josef Schneider Str 2, 97080, Wurzburg, Germany
    Clin Rev Allergy Immunol 34:56-64. 2008
    ....
  29. doi request reprint Methylprednisolone blocks autoantibody-induced tissue damage in experimental models of bullous pemphigoid and epidermolysis bullosa acquisita through inhibition of neutrophil activation
    Lars Hellberg
    Institute of Medical Microbiology and Hygiene, University of Lubeck, Lubeck, Germany
    J Invest Dermatol 133:2390-9. 2013
    ..We here identify the inhibition of Akt, ERK1/2, and p38 MAPK phosphorylation as molecular mechanisms to promote MP's therapeutic effects. ..
  30. ncbi request reprint Current treatment of autoimmune blistering diseases
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, D 23562 Lubeck, Germany
    Curr Drug Discov Technol 6:270-80. 2009
    ..Here, both conventional therapies and novel treatment regimens for autoimmune blistering diseases are discussed...
  31. ncbi request reprint Glucocorticosteroid-resistant pemphigoid gestationis: successful treatment with adjuvant immunoadsorption
    Lilia Westermann
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Dermatol 39:168-71. 2012
    ..5% allowing the reduction of prednisolone to 7.5 mg/day. We conclude that immunoadsorption is an effective and safe adjuvant therapeutic option for severe pemphigoid gestationis...
  32. doi request reprint Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Blood 117:6135-42. 2011
    ..Our results suggest that Hsp90 blockade has no impact on normal or autoreactive plasma cells in vivo and indentify T cells as targets of anti-Hsp90 treatment in autoimmunity to type VII collagen...
  33. doi request reprint Linear IgA disease: successful application of immunoadsorption and review of the literature
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Lubeck, Germany michael kasperkiewicz uk sh de
    Dermatology 220:259-63. 2010
    ..Here, we report a patient with a severe generalized LAD in whom adjuvant tryptophan IA was associated with rapid healing of skin lesions. Our observation suggests that IA may also be a helpful adjuvant treatment option for severe LAD...
  34. doi request reprint Histopathology of anti-laminin 5 mucous membrane pemphigoid
    Christian Rose
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Am Acad Dermatol 61:433-40. 2009
    ..Anti-laminin 5 mucous membrane pemphigoid (MMP) is an autoimmune blistering disease characterized by autoantibodies against the major basement membrane component laminin 5 (laminin 332, epiligrin)...
  35. doi request reprint Generation of antibodies of distinct subclasses and specificity is linked to H2s in an active mouse model of epidermolysis bullosa acquisita
    Ralf J Ludwig
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Invest Dermatol 131:167-76. 2011
    ..Furthermore, our data are the basis for future studies with the goal of identifying non-MHC EBA susceptibility genes...
  36. doi request reprint Rituximab for treatment-refractory pemphigus and pemphigoid: a case series of 17 patients
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Am Acad Dermatol 65:552-8. 2011
    ..However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking...
  37. doi request reprint Immunogenicity of rituximab in patients with severe pemphigus
    Enno Schmidt
    Department of Dermatology, University of Luebeck, Luebeck, Germany
    Clin Immunol 132:334-41. 2009
    ..These observations show that antibodies to rituximab are generated in some patients during rituximab treatment and may be associated with a less favourable response to treatment...
  38. pmc Serological diagnosis of autoimmune bullous skin diseases: prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy
    Nina van Beek
    Department of Dermatology, University of Luebeck, Luebeck, Germany
    Orphanet J Rare Dis 7:49. 2012
    ..BIOCHIP mosaics consisting of different antigen substrates allow polyvalent immunofluorescence (IF) tests and provide antibody profiles in a single incubation...
  39. doi request reprint Immunoadsorption in dermatology
    Damian Meyersburg
    Departments of Dermatology Comprehensive Centre for Inflammation Medicine, University of Lubeck, Lubeck, Germany
    Ther Apher Dial 16:311-20. 2012
    ..Most recently, IA has been successfully applied in patients with severe atopic dermatitis and high total serum IgE levels. Here, the different treatment protocols, clinical efficacy, and adverse events are summarized...
  40. doi request reprint Current therapy of the pemphigus group
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Germany
    Clin Dermatol 30:84-94. 2012
    ..This contribution covers both conventional therapies and most current treatment strategies for pemphigus...
  41. doi request reprint GM-CSF modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita
    Unni Krishna S R L Samavedam
    Department of Dermatology, University of Lubeck, 23563 Lübeck, Germany
    J Immunol 192:559-71. 2014
    ..We demonstrate that GM-CSF modulates both autoantibody production and skin blistering in a prototypical organ-specific autoimmune disease. ..
  42. doi request reprint Efficacy and safety of rituximab in pemphigus: experience of the German Registry of Autoimmune Diseases
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    J Dtsch Dermatol Ges 10:727-32. 2012
    ..However, no systematic evaluation is available to corroborate this observation. The aim of this study was to systematically determine efficacy and safety of rituximab in treatment-resistant pemphigus...
  43. doi request reprint Mapping of B cell epitopes on desmoglein 3 in pemphigus vulgaris patients by the use of overlapping peptides
    Jenny Dworschak
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    J Dermatol Sci 65:102-9. 2012
    ..Previous studies mainly focused on the mapping of conformational epitopes of Dsg 3 using recombinant fragments of Dsg 3 and competition ELISA...
  44. ncbi request reprint Recommendations for the use of immunoapheresis in the treatment of autoimmune bullous diseases
    Detlef Zillikens
    Department of Dermatology, University of Lubeck, Germany
    J Dtsch Dermatol Ges 5:881-7. 2007
    ..A consensus meeting was held in mid-2005 in Hamburg, aiming at developing guidelines for the use of immunoapheresis in the treatment of autoimmune bullous diseases. This paper summarizes the experts' recommendations...
  45. doi request reprint Apoptosis is not required for acantholysis in pemphigus vulgaris
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Am J Physiol Cell Physiol 296:C162-72. 2009
    ..Taken together, we conclude that apoptosis is not a prerequisite for skin blistering in PV but may occur secondary to acantholysis...
  46. ncbi request reprint Serum levels of autoantibodies to desmoglein 3 in patients with therapy-resistant pemphigus vulgaris successfully treated with adjuvant intravenous immunoglobulins
    Susanne Herzog
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Acta Derm Venereol 84:48-52. 2004
    ..It is concluded that the administration of intravenous immunoglobulins was associated with a decrease in circulating autoantibodies and clinical improvement in our patients...
  47. ncbi request reprint Subacute prurigo variant of bullous pemphigoid: autoantibodies show the same specificity compared with classic bullous pemphigoid
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    J Am Acad Dermatol 47:133-6. 2002
    ..Our findings suggest that the subacute prurigo form of BP is a true variant of BP...
  48. pmc Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid
    Stefan Tukaj
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    PLoS ONE 8:e70496. 2013
    ..These findings suggest that Hsp90 may play a pathophysiological role and represent a novel potential treatment target in BP. ..
  49. doi request reprint Emerging treatments for pemphigoid diseases
    Ralf J Ludwig
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Trends Mol Med 19:501-12. 2013
    ..Interestingly, for some of these targets, lead compounds have been developed. Here, we review emerging therapeutic targets for pemphigoid diseases and discuss which compounds are likely be used in the future. ..
  50. doi request reprint Animal models for autoimmune bullous dermatoses
    Katja Bieber
    Institute of Anatomy, University of Lubeck, Lubeck, Germany
    Exp Dermatol 19:2-11. 2010
    ..We here review established and novel animal models of autoimmune skin blistering diseases and discuss their applications and limitations...
  51. ncbi request reprint Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin
    Cassian Sitaru
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    J Invest Dermatol 118:664-71. 2002
    ..Our in vitro results support the idea that autoantibodies to bullous pemphigoid 180 from patients with bullous pemphigoid are of pathogenic relevance...
  52. doi request reprint Diagnostics of autoimmune bullous diseases in German dermatology departments
    Nina van Beek
    Department of Dermatology, Allergology and Venereology, University of Lubeck, Germany
    J Dtsch Dermatol Ges 10:492-9. 2012
    ..The aim of this survey was to describe currently performed diagnostic methods for bullous autoimmune diseases in German dermatology departments...
  53. doi request reprint Concomitant bullous pemphigoid and dermatitis herpetiformis
    Franziska Schulze
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Dermatology 226:217-21. 2013
    ..Interestingly, in previous cases, tissue-bound and serum autoantibodies against the respective target antigens had not yet been completely characterized. ..
  54. doi request reprint Pemphigoid diseases: pathogenesis, diagnosis, and treatment
    Michael Kasperkiewicz
    Department of Dermatology, University of Lubeck, Lubeck, Germany
    Autoimmunity 45:55-70. 2012
    ..This review covers the most recent understanding of the pathophysiology, diagnosis, and treatment of this group of autoimmune diseases...
  55. ncbi request reprint Sun-induced life-threatening lupus nephritis
    Enno Schmidt
    Department of Dermatology, University of Wurzburg, Wurzburg, Germany
    Ann N Y Acad Sci 1108:35-40. 2007
    ..The patient highlights the impact of UV light not only on skin but also on internal organ involvement in LE...