- Five-year outcomes of severe acute kidney injury requiring renal replacement therapyHelmut Schiffl
Department of Internal Medicine Campus Innenstadt, University of Munich, Munich, Germany
Nephrol Dial Transplant 23:2235-41. 2008..Severe acute kidney injury (AKI) is a common occurrence in intensive care. However, few studies have followed up these patients beyond 12 months after hospital discharge...
- Effects of high efficiency post-dilution on-line hemodiafiltration or conventional hemodialysis on residual renal function and left ventricular hypertrophyHelmut Schiffl
KfH Nierenzentrum München Laim, Elsenheimerstr 63, 80687, Munich, Germany
Int Urol Nephrol 45:1389-96. 2013..Our prospective investigation analyzed the effects of different dialytic therapies on RRF and left ventricular hypertrophy, which may be considered--at least in part--a surrogate marker of chronic fluid overload...
- Disease severity adversely affects delivery of dialysis in acute renal failureHelmut Schiffl
Department of Internal Medicine, University of Munich, Munich, Germany
Nephron Clin Pract 107:c163-9. 2007..This observational study was designed to evaluate the impact of disease activity on delivered single pool Kt/V(urea) in ARF patients...
- Severe acute hypophosphatemia during renal replacement therapy adversely affects outcome of critically ill patients with acute kidney injuryHelmut Schiffl
Department of Internal Medicine Campus Innenstadt, University of Munich, Ziemssenstr 1, 80336 Munich, Germany
Int Urol Nephrol 45:191-7. 2013..The purpose of this retrospective analysis of the Acute Renal Support Registry of the University of Munich was to examine the association between severe hypophosphatemia and severity of and recovery from AKI...
- Effects of dialysis purity on uremic dyslipidemiaHelmut Schiffl
KfH Renal Center Munich Laim, Munich, Germany
Ther Apher Dial 14:5-11. 2010..Ultrapure dialysis fluid improves potential parameters of cardiovascular risk by decreasing inflammatory reactions, improving uremic dyslipidemia and lowering oxidative stress...
- Erythropoiesis-stimulating agents, hypertension and left ventricular hypertrophy in the chronic kidney disease patientHolger Schmid
KfH Nierenzentrum Muenchen Laim, Department of Internal Medicine, University Hospital Munich, University of Munich, Munich, Germany
Curr Opin Nephrol Hypertens 20:465-70. 2011..Numerous noninterventional studies in patients with chronic kidney disease (CKD) revealed a consistent relationship of LVH with modifiable risk factors attributable to failing renal function, particularly anemia and hypertension...
- New strategies for managing anemia of chronic kidney diseaseHolger Schmid
KfH Nierenzentrum München Laim, Munich, Germany
Cardiovasc Hematol Agents Med Chem 10:339-51. 2012....
- Ultrapure dialysis fluid slows loss of residual renal function in new dialysis patientsHelmut Schiffl
KfH Dialysezentrum München Laim, Munich, Germany
Nephrol Dial Transplant 17:1814-8. 2002..Our prospective randomised investigation aimed to analyse the effects of the microbiological quality of dialysis fluid on the course of residual renal function after initiation of haemodialysis...
- Acute effects of hemodialysis on lung function in patients with end-stage renal diseaseSusanne M Lang
Division of Pneumology, Department of Medicine, Medizinische Klinik Innenstadt, University of Munich, Germany
Wien Klin Wochenschr 118:108-13. 2006..Regardless of the membrane used, the hemodialysis procedure does not acutely affect lung function in uremic patients on maintenance hemodialysis. Hemodialysis is a safe procedure even in uremic patients with pre-existing lung disease...
- Renal recovery from acute tubular necrosis requiring renal replacement therapy: a prospective study in critically ill patientsHelmut Schiffl
Department of Internal Medicine, University of Munich, Germany
Nephrol Dial Transplant 21:1248-52. 2006..This prospective cohort study was designed to assess the need for short- and long-term dialysis in critically ill patients with severe ATN and to define risk factors for lack of renal recovery...
- Differential diagnosis of bacterial infection and inflammatory response in kidney diseases using procalcitoninThomas Sitter
Department of Nephrology, Medizinische Klinik Innenstadt, Ludwig Maximilians University, Munich, Germany
J Nephrol 15:297-301. 2002....
- Stopping smoking slows accelerated progression of renal failure in primary renal diseaseHelmut Schiffl
Deaprtment of Internal Medicine, Innenstadt, University of Munich, Germany
J Nephrol 15:270-4. 2002..Cigarette smoking accelerates the progression of renal failure in primary kidney diseases. It is not known, however, whether stopping smoking slows this accelerated loss of renal function...
- Transient hyperthyroidism after total parathyroidectomy for tertiary hyperparathyroidism: a report of two casesStephan R Lederer
KfH Nierenzentrum München West and Nephrologisches Zentrum, Campus Innenstadt, Klinikum der Universitat Munchen, Germany
Wien Klin Wochenschr 120:432-4. 2008..These patients should be monitored with thyroid function tests and assessed for clinical signs attributable to thyrotoxicosis...
- Hemodiafiltration and survival of end-stage renal disease patients: the long journey goes onHolger Schmid
Department of Internal Medicine IV Campus Innenstadt, University of Munich, Munich, Germany
Int Urol Nephrol 44:1435-40. 2012..There is an urgent need for further randomized controlled trials to confirm previous findings and to identify those ESRD patients that are likely to benefit mostly from HDF...
- Assessment of dialysis dose in critically ill maintenance dialysis patientsHelmut Schiffl
Department of Internal Medicine IV, University Hospital Munich, Munich, Germany
Ther Apher Dial 18:468-72. 2014..Assessment of dialysis adequacy should be routinely performed in these patients and delivered dialysis should be tracked through the initial clinical course...
- The dark side of high-intensity renal replacement therapy of acute kidney injury in critically ill patientsHelmut Schiffl
KfH Nierenzentrum München Laim, Department of Internal Medicine Campus Innenstadt, University of Munich, Elsenheimerstr 63, 80687, Munchen, Germany
Int Urol Nephrol 42:435-40. 2010..One important area for future investigations is the need to characterize the potential harm of high-dose RRT for AKI in critically ill patients...
- Urinary biomarkers and acute kidney injury in children: the long road to clinical applicationHelmut Schiffl
Department of Internal Medicine IV, University Hospital, University of Munich, Munich, Germany
Pediatr Nephrol 28:837-42. 2013..Prospective randomized interventional trials using exclusively high biomarker levels to define acute kidney injury should demonstrate improved clinical outcomes...
- Update on biomarkers of acute kidney injury: moving closer to clinical impact?Helmut Schiffl
Department of Internal Medicine IV, University of Munich, Munich, Germany
Mol Diagn Ther 16:199-207. 2012..It needs to be shown whether assignment to earlier treatment for AKI on the basis of generally accepted biomarker cut-off levels results in a reduction in mortality and an improvement in recovery of renal function...
- Gadolinium as an alternative contrast agent for diagnostic and interventional angiographic procedures in patients with impaired renal functionJohannes Rieger
Department of Radiology, Medizinische Klinik Innenstadt, Ludwig Maximilians University, Munich, Germany
Nephrol Dial Transplant 17:824-8. 2002....
- Exit-site infections by non-diphtheria corynebacteria in CAPDHelmut Schiffl
KfH Nierenzentrum München Laim, Munich, Germany
Perit Dial Int 24:454-9. 2004..This study highlights the importance of non-diphtheria corynebacteria as emerging nosocomial pathogens in the population of end-stage renal disease patients on on continuous ambulatory peritoneal dialysis...
- Hypertension Secondary to PHPT: Cause or Coincidence?Helmut Schiffl
Department of Internal Medicine Campus Innenstadt, University Hospital, University of Munich, 80336 Munich, Germany
Int J Endocrinol 2011:974647. 2011....
- MELAS: a mitochondrial disorder in an adult patient with a renal transplantStephan R Lederer
KfH Nierenzentrum München West and Nephrologisches Zentrum, Klinikum der Universitat Munchen, Munich, Germany
Wien Klin Wochenschr 122:363-5. 2010..This case report describes a 58-year-old patient with a 40-year course of a multisystemic illness representing the diagnostic challenges of mitochondrial disease...
- Erythropoiesis stimulating agents and anaemia of end-stage renal diseaseHolger Schmid
KfH Nierenzentrum Muenchen Laim, Munich, Germany
Cardiovasc Hematol Agents Med Chem 8:164-72. 2010..The use of ESAs does carry risks such as hypertension, pure red cell aplasia, or cancer, and these agents need to be used judiciously...
- Daily hemodialysis and the outcome of acute renal failureHelmut Schiffl
Department of Nephrology, Medizinische Klinik and Medizinische Poliklinik Innenstadt, Universitat Munchen, Munich, Germany
N Engl J Med 346:305-10. 2002..We performed a prospective study to determine the effect of daily intermittent hemodialysis, as compared with conventional (alternate-day) intermittent hemodialysis, on survival among patients with acute renal failure...
- Folic acid deficiency modifies the haematopoietic response to recombinant human erythropoietin in maintenance dialysis patientsHelmut Schiffl
KfH Nierenzentrum München Laim, Elsenheimerstr 63, D80687 Munich, Germany
Nephrol Dial Transplant 21:133-7. 2006..While folic acid deficiency causes macrocytic anaemia in non-renal patients, the relevance of altered folate metabolism in anaemia of end-stage renal disease and its response to rHu-EPO is less clear...
- Intermittent hemodialysis and/or continuous renal replacement therapy: are they complementary or alternative therapies?Helmut Schiffl
Am J Kidney Dis 40:1097-9. 2002
- Daily haemodialysis for acute renal failureHelmut Schiffl
Department of Nephrology Innenstadt, Ludwig Maximilians University of Munich, Germany
Curr Opin Nephrol Hypertens 11:589-92. 2002..Recent data suggest that alternate day dialysis provides inadequate dialysis dosing in the majority of critically ill patients...
- Fluoridation of drinking water and chronic kidney disease: absence of evidence is not evidence of absenceHelmut Schiffl
Nephrol Dial Transplant 23:411. 2008