Sabine Zitzmann

Summary

Affiliation: Schering AG
Country: Germany

Publications

  1. ncbi Identification and evaluation of a new tumor cell-binding peptide, FROP-1
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
    J Nucl Med 48:965-72. 2007
  2. ncbi Preclinical evaluation of the breast cancer cell-binding peptide, p160
    Vasileios Askoxylakis
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, University of Heidelberg, Germany
    Clin Cancer Res 11:6705-12. 2005
  3. ncbi Characterization and development of a peptide (p160) with affinity for neuroblastoma cells
    Vasileios Askoxylakis
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center DKFZ and University of Heidelberg, Heidelberg, Germany
    J Nucl Med 47:981-8. 2006
  4. ncbi Influence of chelate conjugation on a newly identified tumor-targeting peptide
    Walter Mier
    Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany
    J Nucl Med 48:1545-52. 2007
  5. ncbi Identification of a new prostate-specific cyclic peptide with the bacterial FliTrx system
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    J Nucl Med 46:782-5. 2005
  6. ncbi A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, University of Heidelberg, Heidelberg, Germany
    Clin Cancer Res 11:139-46. 2005
  7. ncbi Effects of Pax8 and TTF-1 thyroid transcription factor gene transfer in hepatoma cells: imaging of functional protein-protein interaction and iodide uptake
    Annette Altmann
    Clinical Cooperation Unit of Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    J Nucl Med 46:831-9. 2005
  8. ncbi Iodide kinetics and dosimetry in vivo after transfer of the human sodium iodide symporter gene in rat thyroid carcinoma cells
    Uwe Haberkorn
    Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany
    J Nucl Med 45:827-33. 2004
  9. ncbi Increased MIBG uptake after transfer of the human norepinephrine transporter gene in rat hepatoma
    Annette Altmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
    J Nucl Med 44:973-80. 2003
  10. ncbi Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo
    Sabine Zitzmann
    Department for Cytogenetics H0400, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Cancer Res 62:5139-43. 2002

Detail Information

Publications10

  1. ncbi Identification and evaluation of a new tumor cell-binding peptide, FROP-1
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
    J Nucl Med 48:965-72. 2007
    ....
  2. ncbi Preclinical evaluation of the breast cancer cell-binding peptide, p160
    Vasileios Askoxylakis
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, University of Heidelberg, Germany
    Clin Cancer Res 11:6705-12. 2005
    ..To develop a peptide-based radiopharmaceutical, we investigated the properties of a peptide with affinity for human breast cancer, which has been selected through phage display...
  3. ncbi Characterization and development of a peptide (p160) with affinity for neuroblastoma cells
    Vasileios Askoxylakis
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center DKFZ and University of Heidelberg, Heidelberg, Germany
    J Nucl Med 47:981-8. 2006
    ..To identify and characterize new carrier molecules, we evaluated a peptide that had been identified by phage display technology...
  4. ncbi Influence of chelate conjugation on a newly identified tumor-targeting peptide
    Walter Mier
    Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany
    J Nucl Med 48:1545-52. 2007
    ..This study investigated whether coupling of a new peptide, FROP-1, to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) resulted in structural restriction and, consequently, improved binding and stability...
  5. ncbi Identification of a new prostate-specific cyclic peptide with the bacterial FliTrx system
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    J Nucl Med 46:782-5. 2005
    ..Peptides are useful tools for directing radioisotopes into tumors. We evaluated the ability of a bacterial peptide display system to isolate new prostate tumor-specific peptides...
  6. ncbi A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy
    Sabine Zitzmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, University of Heidelberg, Heidelberg, Germany
    Clin Cancer Res 11:139-46. 2005
    ..Radiolabeled peptides with high sensitivity and specificity for prostate cancer would be a desirable tool for tumor diagnosis and treatment...
  7. ncbi Effects of Pax8 and TTF-1 thyroid transcription factor gene transfer in hepatoma cells: imaging of functional protein-protein interaction and iodide uptake
    Annette Altmann
    Clinical Cooperation Unit of Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    J Nucl Med 46:831-9. 2005
    ..The thyroid transcription factors TTF-1 and Pax8 cooperate in the transcriptional activation of thyroid-specific genes such as thyroglobulin (Tg), thyroperoxidase (TPO), and sodium/iodide symporter (NIS)...
  8. ncbi Iodide kinetics and dosimetry in vivo after transfer of the human sodium iodide symporter gene in rat thyroid carcinoma cells
    Uwe Haberkorn
    Department of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany
    J Nucl Med 45:827-33. 2004
    ..This study evaluates the iodide kinetics and dosimetry of iodide in hNIS-expressing thyroid carcinoma cells under optimized conditions...
  9. ncbi Increased MIBG uptake after transfer of the human norepinephrine transporter gene in rat hepatoma
    Annette Altmann
    Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
    J Nucl Med 44:973-80. 2003
    ..Therefore, we investigated whether the accumulation of MIBG may be induced by retroviral transfection of the hNET gene in Morris hepatoma cells...
  10. ncbi Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo
    Sabine Zitzmann
    Department for Cytogenetics H0400, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Cancer Res 62:5139-43. 2002
    ..This study suggests, that the RGD-4C-peptide can target tumor endothelial cells as well as tumor cells. Consequently, it should be possible to design a combination therapy approach against both targets...