Research Topics
| Siegmund S WolfSummaryAffiliation: Schering AG Country: Germany Publications
| Collaborators
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Detail Information
Publications
A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the ARSiegmund S Wolf
Gynecology and Andrology, MHCII, Schering AG Jenapharm, Otto Schott Str 15, D 07745 Jena, Germany
Arch Biochem Biophys 460:56-66. 2007..As s-JMJD1C has putative demethylase activity, removal of methylation seems to be important for nuclear receptor-based gene regulation...
PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptorRene Meyer
Gynecology and Andrology, MHCII, Schering AG Jenapharm, Otto Schott Str 15, D 07745 Jena, Germany
J Steroid Biochem Mol Biol 107:1-14. 2007..Thus, it appears that the ligand-dependent AR conformation is essential for the recruitment and nuclear translocation of PMRT2 which acts as AR-coactivator, presumably by arginine methylation...
FoxG1, a member of the forkhead family, is a corepressor of the androgen receptorMaik Obendorf
Schering AG Jenapharm GmbH and Co KG, CRBA G and A, Otto Schott Str 15, D 07745 Jena, Germany
J Steroid Biochem Mol Biol 104:195-207. 2007..Taken together, the data presented suggest that, in addition to repression of transcription by direct binding to DNA, FoxG1 may interact with AR in vivo, thereby targeting its repressor function specifically to sex hormone signaling...
