U Schaeper

Summary

Country: Germany

Publications

  1. pmc Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
    U Schaeper
    Max Delbruck Center for Molecular Medicine, 13092 Berlin, Germany
    J Cell Biol 149:1419-32. 2000
  2. pmc Essential role of Gab1 for signaling by the c-Met receptor in vivo
    M Sachs
    Department of Growth and Differentiation, Max Delbrueck Center for Molecular Medicine, 13092 Berlin, Germany
    J Cell Biol 150:1375-84. 2000

Collaborators

Detail Information

Publications2

  1. pmc Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
    U Schaeper
    Max Delbruck Center for Molecular Medicine, 13092 Berlin, Germany
    J Cell Biol 149:1419-32. 2000
    ..Overexpression of a Gab1 mutant deficient in Shp2 interaction could also block HGF/SF-induced activation of the MAPK pathway, suggesting that Shp2 is critical for c-Met/Gab1-specific signaling...
  2. pmc Essential role of Gab1 for signaling by the c-Met receptor in vivo
    M Sachs
    Department of Growth and Differentiation, Max Delbrueck Center for Molecular Medicine, 13092 Berlin, Germany
    J Cell Biol 150:1375-84. 2000
    ..This is genetic evidence that Gab1 is essential for c-Met signaling in vivo. Analogy exists to signal transmission by insulin receptors, which require IRS1 and IRS2 as specific docking proteins...