Michael Sand

Summary

Country: Germany

Publications

  1. Sand M, Bechara F, Sand D, Mann B. Surgical and medical emergencies on board European aircraft: a retrospective study of 10189 cases. Crit Care. 2009;13:R3 pubmed publisher
    ..The study demonstrates that although aviation is regulated by a variety of national and international laws, standardised documentation of IMEs is inadequate and needs further development. ..
  2. Sand M, Bechara F, Sand D, Radenhausen M, Tomi N, Altmeyer P, et al. Extracorporeal photopheresis as a treatment for patients with severe, refractory atopic dermatitis. Dermatology. 2007;215:134-8 pubmed
    ..However, larger studies are needed to further evaluate its therapeutic potential. ..
  3. Sand M, Sand D, Brors D, Altmeyer P, Mann B, Bechara F. Cutaneous lesions of the external ear. Head Face Med. 2008;4:2 pubmed publisher
    ..This article will focus on those diseases wherefore surgery or laser therapy is considered as a possible treatment option or which are potentially subject to surgical evaluation. ..
  4. Sand M, Gambichler T, Sand D, Altmeyer P, Stuecker M, Bechara F. Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi. Eur J Dermatol. 2011;21:18-21 pubmed publisher
    ..This preliminary study indicates that alterations in the miRNA machinery could exist and should be subject of further investigation. ..
  5. Sand M, Hessam S, Sand D, Bechara F, Vorstius C, Bromba M, et al. Stress-coping styles of 459 emergency care physicians in Germany : A pilot study. Anaesthesist. 2016;65:841-846 pubmed
    ..For clinical practice and policy-making, structural changes in work patterns and psychological support should be considered, which may be of particular benefit for female ECPs. ..
  6. Sand M, Bechara F, Kopp J, Krins N, Behringer D, Mann B. Gallbladder metastasis from renal cell carcinoma mimicking acute cholecystitis. Eur J Med Res. 2009;14:90-2 pubmed
    ..In this case we present a patient who developed a gallbladder metastasis five years after a renal cell carcinoma mimicking acute cholecystitis. ..
  7. Sand M, Skrygan M, Sand D, Georgas D, Gambichler T, Hahn S, et al. Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases, and benign melanocytic nevi. Cell Tissue Res. 2013;351:85-98 pubmed publisher
    ..However, we report several novel miRNA candidates in CMM tumors; these miRNA sequences require further validation and functional analysis to evaluate whether they play a role in the pathogenesis of CMM. ..
  8. Sand M, Bechara F, Gambichler T, Sand D, Friedländer M, Bromba M, et al. Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study. Ann Oncol. 2016;27:332-8 pubmed publisher
    ..Thus, larger studies are necessary, but are not preferable at this time if other options are available. ..
  9. Sand M, Bechara F, Skrygan M, Sand D, Gambichler T, Bromba M, et al. Mutation Scanning of D1705 and D1709 in the RNAse IIIb Domain of MicroRNA Processing Enzyme Dicer in Cutaneous Melanoma. Pathol Oncol Res. 2016;22:639-41 pubmed publisher
    ..The miRNA processing enzyme Dicer of melanoma and melanoma metastasis does not appear to be affected by mutation in the metal-ion-binding sites D1709 and D1705 of its RNase IIIb domain. ..

More Information

Publications16

  1. Sand M, Bechara F, Sand D, Gambichler T, Hahn S, Bromba M, et al. Long-noncoding RNAs in basal cell carcinoma. Tumour Biol. 2016;37:10595-608 pubmed publisher
    ..BCC showed a significantly altered lncRNA and mRNA expression profile. Dysregulation of previously described lncRNAs may play a role in the molecular pathogenesis of BCC and should be subject of further analysis. ..
  2. Sand M, Bechara F, Gambichler T, Sand D, Bromba M, Hahn S, et al. Circular RNA expression in cutaneous squamous cell carcinoma. J Dermatol Sci. 2016;83:210-8 pubmed publisher
    ..This study showed that circRNAs are differentially expressed in cSCC and play an important role in tumor formation by interfering with cSCC relevant miRNAs through miRNA sequence complementary MREs participating in epigenetic control. ..
  3. Sand M, Hessam S, Amur S, Skrygan M, Bromba M, Stockfleth E, et al. Expression of oncogenic miR-17-92 and tumor suppressive miR-143-145 clusters in basal cell carcinoma and cutaneous squamous cell carcinoma. J Dermatol Sci. 2017;86:142-148 pubmed publisher
    ..This study marks the first evidence for the participation of members of the miR-17-92 cluster in cSCC and miR-143-145 cluster in BCC. ..
  4. Sand M, Sand D, Boorboor P, Mann B, Altmeyer P, Hoffmann K, et al. Combination of surgical excision and custom designed silicon pressure splint therapy for keloids on the helical rim. Head Face Med. 2007;3:14 pubmed
    ..We report a case of a large ear keloid on the helical rim which was successfully treated with surgery and a custom designed silicon pressure clip...
  5. Sand M, Boorboor P, Sand D, Altmeyer P, Mann B, Bechara F. Bilateral cheek-to-nose advancement flap: an alternative to the paramedian forehead flap for reconstruction of the nose. Acta Chir Plast. 2007;49:67-70 pubmed
    ..The bilateral cheek-to-nose advancement flap is a reliable tool in the interventional portfolio of the reconstructive surgeon...
  6. Sand M, Gambichler T, Skrygan M, Sand D, Scola N, Altmeyer P, et al. Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer. Cancer Invest. 2010;28:649-53 pubmed publisher
    ..05). We observed dysregulation of Drosha and Dicer expression in epithelial tumors when compared to healthy control samples. Therefore, we favor the hypothesis that miRNAs are involved in the carcinogenesis of epithelial skin cancer. ..
  7. Sand M, Skrygan M, Sand D, Georgas D, Hahn S, Gambichler T, et al. Expression of microRNAs in basal cell carcinoma. Br J Dermatol. 2012;167:847-55 pubmed publisher
    ..This study identified several miRNA candidates that may play a role in the molecular pathogenesis of BCC. ..