Research Topics
Genomes and Genes | B F M RomeikeSummaryAffiliation: Saarland University Country: Germany Publications
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Publications
Proximal chromosome 11p contiguous gene deletion syndrome phenotype: case report and review of the literatureB F M Romeike
Institute of Neuropathology, Saarland University, School of Medicine, 66421 Homburg Saar, Germany
Clin Neuropathol 26:1-11. 2007..To the best of our knowledge, the present patient is the oldest one so far described with PSS phenotype and the only case that has undergone detailed neuropathological investigation...- Diffuse high-grade gliomas as second malignant neoplasms after radio-chemotherapy for pediatric malignanciesBernd F M Romeike
Institut für Neuropathologie, Universitatsklinikum des Saarlandes, 66421, Homburg Saar, Germany
Childs Nerv Syst 23:185-93. 2007..Diffuse high-grade gliomas are known to develop in children after cranial irradiation for other malignancies. Here, clinicopathological characteristics are outlined... - Automated nuclear segmentation in the determination of the Ki-67 labeling index in meningiomasY J Kim
Institute of Neuropathology, University of the Saarland, School of Medicine, Homburg Saar, Germany
Clin Neuropathol 25:67-73. 2006..Therefore, an automated computer-based method was developed, which is able to identify and analyze immunolabeled and hematoxylin-stained nuclei in digital images of routine immunohistochemical slides... - Immunohistochemical detection of dUTPase in intracranial tumorsB F M Romeike
Institut für Neuropathologie, Geb 90 3, Universitatsklinikum des Saarlandes, D 66421 Homburg, Germany
Pathol Res Pract 201:727-32. 2005..In summary, dUTPase staining provides a useful measure of cell proliferation distinct from that offered by Ki-67 labeling. It proved particularly useful for the evaluation of diffuse astrocytomas... - Serological immune response to cancer testis antigens in patients with pancreatic cancerAndreas Wadle
Department of Internal Medicine I, University of Saarland Medical School, Homburg/Saar, Germany
Int J Cancer 119:117-25. 2006..These results indicate that identification of additional tumor antigens by serological screening of tumor cDNA expression libraries by RAYS is a promising goal in pancreatic cancer... - Assessment of tumor cell invasion factors in gliomatosis cerebriChristian Mawrin
Institut für Neuropathologie, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
J Neurooncol 73:109-15. 2005.... - Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECTDirk Hellwig
Department of Nuclear Medicine, Saarland University Medical Center, 66421 Homburg Saar, Germany
Eur J Nucl Med Mol Imaging 32:1041-9. 2005.... - Action and efficacy of p-[131I]iodo-L-phenylalanine on primary human glioma cell cultures and rats with C6-gliomasBernd F M Romeike
Institute for Neuropathology, University of the Saarland, School of Medicine, D 66421 Homburg, Germany
Anticancer Res 24:3971-6. 2004..Here we describe the potency of the iodine-131-labelled analogue p-[131I]iodo-L-phenylalanine (IPA-131) for experimental treatment of gliomas... - Expression of cancer testis antigens in pancreatic carcinoma cell lines, pancreatic adenocarcinoma and chronic pancreatitisBoris Kubuschok
Department of Internal Medicine I, University of Saarland Medical School, Homburg/Saar, Germany
Int J Cancer 109:568-75. 2004..SCP-1 and GAGE represent promising candidates for vaccine development in pancreatic carcinoma. Whether SCP-1 and GAGE expression identify cases of chronic pancreatitis with a high risk of malignant transformation remains to be shown... - The putative serine/threonine kinase gene STK15 on chromosome 20q13.2 is amplified in human gliomasWilfried Reichardt
Institute of Human Genetics, Saarland University, Saarland University Hospital, Homburg Saar, Germany
Oncol Rep 10:1275-9. 2003..We hypothesize that amplification of the STK15 gene may be a non-random genetic alteration in human gliomas playing a role in the genetic pathways of tumorigenesis... - Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomasRudolf Schmits
Department of Medicine, Saarland University Medical School, Homburg, Germany
Int J Cancer 98:73-7. 2002..We conclude that although astrocytomas express a broad spectrum of antigens, they elicit antibody responses only rarely, most likely because of their intrinsic immunosuppressive effects... - Clinical value of iodine-123-alpha-methyl-L-tyrosine single-photon emission tomography in the differential diagnosis of recurrent brain tumor in patients pretreated for glioma at follow-upSamuel Samnick
Department of Nuclear Medicine, Saarland University Medical Center, Homburg Saar, Germany
J Clin Oncol 20:396-404. 2002..To assess the clinical potential of iodine-123-alpha-methyl-L-tyrosine (IMT) and single-photon emission tomography (SPET) in the differential diagnosis of recurrences in patients pretreated for gliomas at follow-up...