Research Topics
Species | Y MehraeinSummaryAffiliation: Saarland University Country: Germany Publications
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Detail Information
Publications
Detection of parvovirus B19 capsid proteins in lymphocytic cells in synovial tissue of autoimmune chronic arthritisYasmin Mehraein
Department of Human Genetics, Saarland University, University Hospital, Homburg Saar, Germany
Mod Pathol 16:811-7. 2003..B19-positive cells in the synovia could be ascribed to CD20- or CD3-positive B- or T-lymphocytes by double immunostaining. Based on these results, B19 infection of lymphocytic cells also seems possible...- Latent Epstein-Barr virus (EBV) infection and cytomegalovirus (CMV) infection in synovial tissue of autoimmune chronic arthritis determined by RNA- and DNA-in situ hybridizationYasmin Mehraein
Department of Human Genetics, Saarland University, University Hospital, Homburg Saar, Germany
Mod Pathol 17:781-9. 2004..3% of cases. The evidence of increased synovial persistence of EBV, CMV, or B19 either alone or even more as coinciding infections may further reinforce the notion of a primary role of these viruses in autoimmune arthritis... 
Parvovirus B19 detected in Rosai-Dorfman disease in nodal and extranodal manifestationsY Mehraein
Institute of Human Genetics, Saarland University, University Hospital, Homburg Saar, Germany
J Clin Pathol 59:1320-6. 2006..This is the first report of B19 infection in RDD tissue, indicating that B19 may be associated with the pathogenesis of SHML...- Replicative multivirus infection with cytomegalovirus, herpes simplex virus 1, and parvovirus B19, and latent Epstein-Barr virus infection in the synovial tissue of a psoriatic arthritis patientYasmin Mehraein
Department of Human Genetics, Saarland University, University Hospital, Bldg 60, 66421 Homburg Saar, Germany
J Clin Virol 31:25-31. 2004..Psoriatic arthropathy occurs as complicating feature in about 5-7% of psoriasis patients. Infectious mechanisms including viral antigens have been suggested by serologic data as CD8 T cellular specifity towards viral epitopes... - Somatic mosaicism of chromosome 7 in a highly proliferating melanocytic congenital naevus in a ring chromosome 7 patientYasmin Mehraein
Department of Human Genetics, Saarland University, University Hospital, Homburg Saar, Germany
Am J Med Genet A 131:179-85. 2004.... - Human endogenous retrovirus HERV-K(HML-2) Rec expression and transcriptional activities in normal and rheumatoid arthritis synoviaSandra Ehlhardt
Department of Human Genetics and Department of Dermatology, Saarland University, University Hospital, Homburg/Saar, Germany
J Rheumatol 33:16-23. 2006..Differences in the expression of HERV-K env-derived transcripts in RA synovia may be caused by disease-specific changes in the general expression pattern... - Parvovirus B19-related chronic monoarthritis: immunohistochemical detection of virus-positive lymphocytes within the synovial tissue compartment: two reported casesCarsten Lennerz
Department of Human Genetics, , Saarland University, , 66421, Homburg/Saar, Germany
Clin Rheumatol 23:59-62. 2004..In conclusion, respective virus diagnostics should be considered even in chronic monosymptomatic arthritic lesions. The pathology of B19 arthropathy seems to be due to direct virus infection of cells within the synovia... - Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancerM Seifert
Department of Human Genetics, Saarland University, University Hospital, Homburg Saar, Germany
J Pathol 205:623-32. 2005..A contribution to tumour progression or metastasis could not, however, be proven. Elucidation of the specific mechanisms by which the nm23 homologues nm23-H4, -H6, and -H7 are involved in tumour development requires further studies... - Expression analysis of human intersectin 2 gene (ITSN2) minor splice variants showing differential expression in normal human brainMarkus Seifert
Department of Human Genetics, Saarland University Hospital, Homburg, Saar, Germany
Oncol Rep 17:1207-11. 2007..These results indicate that ITSN2C may be specifically expressed in neurons hinting to a physiologic role in neuronal cell function... - Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activityJens Mayer
Department of Human Genetics, Medical Faculty, University of Saarland, 66421 Homburg Saar, Germany
Virology 322:190-8. 2004..Extended studies will eventually yield a more complete image of HERV transcription, regulation, and biological significance in diverse human tissues... - PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformationMei Yu
Abteilung Biochemie und Molekularbiologie, Institut fur Biochemie, Klinikum der RWTH, Pauwelsstrasse 30, 52057 Aachen, Germany
Oncogene 24:1982-93. 2005..Together, our findings define a novel PARP enzyme involved in the control of cell proliferation... - Haematopoietic stem cells improve cardiac function after infarction without permanent cardiac engraftmentFlorian P Limbourg
Department of Cardiology and Angiology, Medizinische Hochschule Hannover, Germany
Eur J Heart Fail 7:722-9. 2005..However, the cell population mediating myocardial recovery and the fate of the transplanted cells are still controversial...