Sascha Kreuer

Summary

Affiliation: Saarland University
Country: Germany

Publications

  1. ncbi request reprint The Narcotrend monitor
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Best Pract Res Clin Anaesthesiol 20:111-9. 2006
  2. ncbi request reprint Comparison of BIS and AAI as measures of anaesthetic drug effect during desflurane-remifentanil anaesthesia
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Acta Anaesthesiol Scand 48:1168-73. 2004
  3. ncbi request reprint Narcotrend or bispectral index monitoring during desflurane-remifentanil anesthesia: a comparison with a standard practice protocol
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesth Analg 101:427-34, table of contents. 2005
  4. ncbi request reprint Application of Bispectral Index and Narcotrend index to the measurement of the electroencephalographic effects of isoflurane with and without burst suppression
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesthesiology 101:847-54. 2004
  5. ncbi request reprint A-line, bispectral index, and estimated effect-site concentrations: a prediction of clinical end-points of anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Anesth Analg 102:1141-6. 2006
  6. ncbi request reprint Comparability of Narcotrend index and bispectral index during propofol anaesthesia
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Br J Anaesth 93:235-40. 2004
  7. doi request reprint Failure of two commercial indexes and spectral parameters to reflect the pharmacodynamic effect of desflurane on EEG
    Sascha Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, 66421, Homburg Saar, Saarland, Germany
    J Clin Monit Comput 22:149-58. 2008
  8. doi request reprint Comparative pharmacodynamic modeling of desflurane, sevoflurane and isoflurane
    Sascha Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Saarland, Germany
    J Clin Monit Comput 23:299-305. 2009
  9. doi request reprint Comparative pharmacodynamic modeling using bispectral and narcotrend-index with and without a pharmacodynamic plateau during sevoflurane anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesth Analg 106:1171-81, table of contents. 2008
  10. ncbi request reprint [Narcotrend stages and end-tidal desflurane concentrations. An investigation during recovery from desflurane/remifentanil anaesthesia]
    S Kreuer
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, Homburg Saar, Germany
    Anaesthesist 51:800-4. 2002

Detail Information

Publications41

  1. ncbi request reprint The Narcotrend monitor
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Best Pract Res Clin Anaesthesiol 20:111-9. 2006
    ..Multiple clinical and validation studies are available for the Narcotrend monitor, including comparisons with the BIS monitor (Aspect Medical Systems, Natick, USA)...
  2. ncbi request reprint Comparison of BIS and AAI as measures of anaesthetic drug effect during desflurane-remifentanil anaesthesia
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Acta Anaesthesiol Scand 48:1168-73. 2004
    ..4) or the bispectral index (Aspect Medical Systems, Newton, MA, USA, version XP)...
  3. ncbi request reprint Narcotrend or bispectral index monitoring during desflurane-remifentanil anesthesia: a comparison with a standard practice protocol
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesth Analg 101:427-34, table of contents. 2005
    ....
  4. ncbi request reprint Application of Bispectral Index and Narcotrend index to the measurement of the electroencephalographic effects of isoflurane with and without burst suppression
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesthesiology 101:847-54. 2004
    ..0) to the Bispectral Index (BIS, version XP; Aspect Medical Systems, Natick, MA) as electroencephalographic measures of isoflurane drug effect during general anesthesia...
  5. ncbi request reprint A-line, bispectral index, and estimated effect-site concentrations: a prediction of clinical end-points of anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Anesth Analg 102:1141-6. 2006
    ..75 for AAI and r = 0.80 for BIS). The correlation between BIS and clinical end-points of anesthesia or the desflurane effect-compartment concentration is better than for the AAI...
  6. ncbi request reprint Comparability of Narcotrend index and bispectral index during propofol anaesthesia
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Br J Anaesth 93:235-40. 2004
    ..We compared the relationship between BIS and NCT values during propofol anaesthesia...
  7. doi request reprint Failure of two commercial indexes and spectral parameters to reflect the pharmacodynamic effect of desflurane on EEG
    Sascha Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, 66421, Homburg Saar, Saarland, Germany
    J Clin Monit Comput 22:149-58. 2008
    ..Bispectral (BIS, Aspect Medical Systems, Natick, MA, version XP) and Narcotrend (NCT, MonitorTechnik, Bad Bramstedt, Germany, Version 4.0) indices were used as an electroencephalographic measure of desflurane drug effect...
  8. doi request reprint Comparative pharmacodynamic modeling of desflurane, sevoflurane and isoflurane
    Sascha Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Saarland, Germany
    J Clin Monit Comput 23:299-305. 2009
    ..The EEG parameters Bispectral index (BIS, Aspect Medical Systems, Natick, MA, version XP) and Narcotrend index (MonitorTechnik, Bad Bramstedt, Germany, version 4.0) were used as measures of the pharmacodynamic effect...
  9. doi request reprint Comparative pharmacodynamic modeling using bispectral and narcotrend-index with and without a pharmacodynamic plateau during sevoflurane anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421 Homburg Saar, Germany
    Anesth Analg 106:1171-81, table of contents. 2008
    ..0) were used as an electroencephalographic measure of sevoflurane drug effect. In addition, we tried to analyze the origin of the plateau...
  10. ncbi request reprint [Narcotrend stages and end-tidal desflurane concentrations. An investigation during recovery from desflurane/remifentanil anaesthesia]
    S Kreuer
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, Homburg Saar, Germany
    Anaesthesist 51:800-4. 2002
    ..0 AF) and end-tidal desflurane concentrations and to identify the pattern of changes of the Narcotrend stages during recovery...
  11. ncbi request reprint Maximizing prediction probability PK as an alternative semiparametric approach to estimate the plasma effect-site equilibration rate constant ke0
    Richard K Ellerkmann
    Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
    Anesth Analg 109:1470-8. 2009
    ..In this study, we introduce a new semiparametric approach calculating k(e)(0) values for isoflurane, sevoflurane, and desflurane by maximizing the prediction probability P(K)...
  12. ncbi request reprint Spectral entropy and bispectral index as measures of the electroencephalographic effects of propofol
    Richard Klaus Ellerkmann
    Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Germany
    Anesth Analg 102:1456-62. 2006
    ..77 +/- 0.09, 0.76 +/- 0.10, and 0.84 +/- 0.06, respectively. BIS seems to show slight advantages in predicting propofol effect-site concentrations compared with SE and RE, as measured by P(K) but not as measured by R2...
  13. ncbi request reprint Narcotrend monitoring allows faster emergence and a reduction of drug consumption in propofol-remifentanil anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Anesthesiology 99:34-41. 2003
    ..This study was designed to investigate the impact of Narcotrend monitoring on recovery times and propofol consumption in comparison to Bispectral Index (BIS) monitoring or standard anesthetic practice...
  14. ncbi request reprint Narcotrend index versus bispectral index as electroencephalogram measures of anesthetic drug effect during propofol anesthesia
    Sascha Kreuer
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, Homburg Saar, Germany
    Anesth Analg 98:692-7, table of contents. 2004
    ..In terms of prediction probability, the performance of the Narcotrend index and the bispectral index to predict propofol effect site concentrations was comparable...
  15. ncbi request reprint The correlation of the bispectral index with propofol effect site concentrations is not altered by epochs indicated as artefact-loaded by narcotrend
    Richard K Ellerkmann
    Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
    J Clin Monit Comput 18:283-7. 2004
    ..0) excludes more EEG epochs because of artefacts than bispectral index monitoring (BIS, Aspect Medical Systems, Newton, MA, version XP). Whether this increased exclusion of epochs is justified has not been investigated yet...
  16. ncbi request reprint Spectral entropy and bispectral index as measures of the electroencephalographic effects of sevoflurane
    Richard Klaus Ellerkmann
    Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
    Anesthesiology 101:1275-82. 2004
    ..8-32 Hz and a response entropy (RE) computed over the frequency range of 0.8-47 Hz. The authors investigated the dose-response relation of SE and RE during sevoflurane anesthesia in comparison with the Bispectral Index (BIS)...
  17. ncbi request reprint Bispectral index and A-line AAI index as guidance for desflurane-remifentanil anaesthesia compared with a standard practice group: a multicentre study
    J Bruhn
    Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Germany
    Br J Anaesth 94:63-9. 2005
    ....
  18. ncbi request reprint Impact of patient age on propofol consumption during propofol-remifentanil anaesthesia
    S Kreuer
    University of Saarland, Department of Anaesthesiology and Intensive Care Medicine, Homburg Saar, Germany
    Eur J Anaesthesiol 22:123-8. 2005
    ..The Narcotrend is a monitor for measuring the depth of anaesthesia based upon a six-letter classification from A (awake) to F (increasing burst suppression) including 14 substages...
  19. ncbi request reprint Comparison of Alaris AEP index and bispectral index during propofol-remifentanil anaesthesia
    S Kreuer
    Department of Anaesthesiology and Intensive Care Medicine, University of Saarland, D 66421 Homburg Saar, Germany
    Br J Anaesth 91:336-40. 2003
    ..It generates an "Alaris AEP index" (AAI), which is a dimensionless number scaled from 100 (awake) to 0. This study was designed to compare AAI and BIS(TM) (Aspect, USA, version XP) values at different levels of anaesthesia...
  20. ncbi request reprint Impact of deep hypothermic circulatory arrest on the BIS index
    Stephan Ziegeler
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University of Saarland, 66421 Homburg Saar, Germany
    J Clin Anesth 22:340-5. 2010
    ..To investigate the influence of duration of deep hypothermic circulatory arrest (DHCA) on recovery of the bispectral index (BIS)...
  21. ncbi request reprint The Narcotrend--a new EEG monitor designed to measure the depth of anaesthesia. A comparison with bispectral index monitoring during propofol-remifentanil-anaesthesia
    S Kreuer
    , , 66421 Homburg/Saar
    Anaesthesist 50:921-5. 2001
    ..The Narcotrend stages D or E are assumed equivalent to BIS values between 64 and 40 indicating general anaesthesia...
  22. ncbi request reprint [Narcotrend EEG monitoring during total intravenous anaesthesia in 4.630 patients]
    W Wilhelm
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, Homburg Saar
    Anaesthesist 51:980-8. 2002
    ....
  23. doi request reprint Brain monitoring revisited: what is it all about?
    Richard K Ellerkmann
    Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
    Best Pract Res Clin Anaesthesiol 27:225-33. 2013
    ..However a study demonstrating both a reduced intraoperative drug consumption and at the same time a reduction of intraoperative awareness due to the use of brain-monitoring devices has not been published yet. ..
  24. ncbi request reprint The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy
    Ulrich Grundmann
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, D 66421 Homburg Saar, Germany
    Anesth Analg 103:217-22, table of contents. 2006
    ..These results suggest that in patients undergoing lumbar microdiscectomy, metamizol is superior to parecoxib, paracetamol, and placebo for immediate postoperative pain relief with minimal side effects...
  25. ncbi request reprint [Desflurane and isoflurane in minimal-flow anesthesia. Consumption and costs with forced fresh gas reduction]
    H Buchinger
    Klinik fur Anaesthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum des Saarlandes, 66421 Homburg Saar
    Anaesthesist 55:854-60. 2006
    ..In the present investigation we compared the consumption of desflurane (DES) and isoflurane (ISO) using a standardized minimal-flow protocol with a forced reduction of the fresh gas flow (FGF)...
  26. doi request reprint Patient state index vs bispectral index as measures of the electroencephalographic effects of propofol
    M Soehle
    Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Br J Anaesth 105:172-8. 2010
    ..The patient state index (PSI) and the bispectral index (BIS) quantify anaesthetic depth based on the EEG using different algorithms. We compared both indices with regard to the prediction of the depth of propofol anaesthesia...
  27. ncbi request reprint [Bispectral index and desflurane concentration below 1 MAC]
    M Wrobel
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes
    Anaesthesist 53:36-40. 2004
    ....
  28. ncbi request reprint [Remifentanil. An update]
    W Wilhelm
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, Homburg Saar
    Anaesthesist 52:473-94. 2003
    ..In addition, present data on the use of remifentanil for analgesia and sedation of the critically ill patient are summarized...
  29. ncbi request reprint Dobutamine improves liver function after hemorrhagic shock through induction of heme oxygenase-1
    Alexander Raddatz
    Klinik für Anaesthesiologie und Intensivmedizin, Universitat des Saarlandes, D 66421 Homburg Saar, Germany
    Am J Respir Crit Care Med 174:198-207. 2006
    ..Induction of heme oxygenase-1 (HO-1) protects the liver against reperfusion injury after hemorrhagic shock. Previous data suggest that the beta(1)-adrenoceptor agonist dobutamine induces HO-1 in hepatocytes...
  30. ncbi request reprint Hemodynamic response to exercise as measured by the solar IKG impedance cardiography module and correlation with metabolic variables
    Stephan Ziegeler
    Department of Anesthesiology and Intensive Care Medicine, University of Saarland, 66421, Homburg Saar, Germany
    J Clin Monit Comput 21:13-20. 2007
    ..Aim of this investigation was the correlation of hemodynamic variables under exercise as measured by a specific ICG-monitor (Solar IKG-Modul, Version 3.0, GE-Healthcare, Freiburg, Germany) with metabolic variables...
  31. doi request reprint The performance of six pulse oximeters in the environment of neuronavigation
    Alexander M Mathes
    Department of Anesthesiology, Critical Care and Pain Medicine, Saarland University Hospital, Homburg Saar, Germany
    Anesth Analg 107:541-4. 2008
    ..In this study, we evaluated the effect of a neurosurgical image guidance system on the performance of six different pulse oximeters. Two simple shielding methods were evaluated...
  32. pmc The place for short-acting opioids: special emphasis on remifentanil
    Wolfram Wilhelm
    Department of Anesthesiology and Intensive Care Medicine, Klinikum St, Marien Hospital Lünen, 44534 Lünen, Altstadtstrasse, Germany
    Crit Care 12:S5. 2008
    ..It summarizes the currently available study data regarding remifentanil and provides recommendations for clinical use of this agent...
  33. ncbi request reprint [Remifentanil-propofol versus fentanyl-midazolam combinations for intracranial surgery: influence of anaesthesia technique and intensive sedation on ventilation times and duration of stay in the ICU]
    C Bauer
    Klinik fur Anaesthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum des Saarlandes, 66421, Homburg Saar, Deutschland
    Anaesthesist 56:128-32. 2007
    ..In this retrospective study two different strategies of anaesthesia technique and ICU sedation (fentanyl-midazolam versus remifentanil-propofol) were compared...
  34. ncbi request reprint Comparison of the effects of remifentanil or fentanyl on anaesthetic induction characteristics of propofol, thiopental or etomidate
    W Wilhelm
    University of Saarland, Department of Anaesthesiology and Intensive Care Medicine, Homburg Saar, Germany
    Eur J Anaesthesiol 19:350-6. 2002
    ..This prospective, randomized, double-blinded study was designed to compare the effects of remifentanil or fentanyl on anaesthetic induction characteristics of propofol, thiopental or etomidate...
  35. ncbi request reprint Accuracy of portable quantitative capnometers and capnographs under prehospital conditions
    Andreas E Biedler
    Klinik für Anaesthesiologie und Intensivmedizin, Universitatskliniken des Saarlandes, 66421 Homburg Saar, Germany
    Am J Emerg Med 21:520-4. 2003
    ..Our results indicate that portable quantitative capnometers are able to fulfill accuracy requirements as requested by international standards but can be affected by changing ambient temperatures...
  36. ncbi request reprint [Influence of gender on propofol consumption and recovery times]
    W Wilhelm
    Klinik fur Anasthesiologie und Operative Intensivmedizin, St Marien Hospital, Lünen
    Anaesthesist 54:567-74. 2005
    ..We investigated gender differences of drug consumption and recovery times for propofol-remifentanil anaesthesia...
  37. doi request reprint [Target-controlled infusion (TCI) - a concept with a future?: state-of-the-art, treatment recommendations and a look into the future]
    S Schraag
    Department of Perioperative Medicine, Golden Jubilee National Hospital, Beardmore Street, Clydebank, Glasgow, Scotland, UK
    Anaesthesist 57:223-30. 2008
    ..The aim is to provide a comprehensive reference based on clinically proven evidence...
  38. ncbi request reprint [The Narcotrend monitor. Development and interpretation algorithms]
    B Schultz
    Klinikum Hannover Oststadt, Medizinische Hochschule Hannover
    Anaesthesist 52:1143-8. 2003
    ..The EEG can be recorded from a frontal channel using standard ECG electrodes, other electrode positions and types can be chosen. The device has been clinically and scientifically validated...
  39. ncbi request reprint The influence of the click stimulus of the Alaris AEP monitor on the depth of anesthesia
    S Kreuer
    Anesth Analg 97:604. 2003
  40. ncbi request reprint [Pharmacokinetic-pharmacodynamic models for inhaled anaesthetics]
    S Kreuer
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum des Saarlandes, 66421 Homburg Saar
    Anaesthesist 56:538-56. 2007
    ..However, there are relatively few investigations on the interactions between the clinically widely used combination of volatile anaesthetics, N(2)O and opioids...
  41. ncbi request reprint Reduction in anaesthetic drug consumption is correlated with mean titrated intra-operative Bispectral Index values
    R K Ellerkmann
    Department of Anaesthesiology, University of Bonn, Bonn, Germany
    Acta Anaesthesiol Scand 50:1244-9. 2006
    ..However, the amount of reduction varied widely between 1% and 40%. We investigated the correlation between reduction in anaesthetic drug consumption and mean titrated BIS values...